| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.198953 |
| RIGI | RNA sensor RIG-I | 0.0812109 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.079576 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0780026 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0758269 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0692477 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0656621 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0609097 |
| TXNIP | thioredoxin interacting protein | 0.0577004 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.052197 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0507719 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0503969 |
| TXNRD1 | thioredoxin reductase 1 | 0.0503717 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0471186 |
| CEP250 | centrosomal protein 250kDa | 0.0465933 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0433064 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0409851 |
| ZNF292 | zinc finger protein 292 | 0.0400609 |
| IL6ST | interleukin 6 signal transducer | 0.0397591 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0385451 |
| INTS6 | integrator complex subunit 6 | 0.0376922 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0374032 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0364162 |
| HDAC9 | histone deacetylase 9 | 0.0359821 |
| H1-0 | H1.0 linker histone | 0.0354854 |
| ADM | adrenomedullin | 0.0352378 |
| KLF10 | Kruppel-like factor 10 | 0.0346148 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0345026 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0341713 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0332858 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.032053 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0320315 |
| EZR | ezrin | 0.03165 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0316254 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.030752 |
| ZC3H6 | zinc finger CCCH-type containing 6 | 0.030561 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0303471 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0290578 |
| HOMER1 | homer scaffolding protein 1 | 0.0288357 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.028487 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0283418 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0281929 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0280181 |
| ARRDC3 | arrestin domain containing 3 | 0.0279904 |
| NOCT | nocturnin | 0.027678 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0263461 |
| WTAP | Wilms tumor 1 associated protein | 0.0260368 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0260072 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0256401 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0254695 |
| FRMD6 | FERM domain containing 6 | 0.0249373 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0239477 |
| CEP295 | centrosomal protein 295kDa | 0.0239202 |
| FNIP1 | folliculin interacting protein 1 | 0.023869 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0238392 |
| PGK1 | phosphoglycerate kinase 1 | 0.0237953 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0237706 |
| RSF1 | remodeling and spacing factor 1 | 0.0237166 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.023694 |
| ATF4 | activating transcription factor 4 | 0.0236466 |
| RPL23 | ribosomal protein L23 | 0.0230901 |
| AHI1 | Abelson helper integration site 1 | 0.0230424 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0226696 |
| PKM | pyruvate kinase, muscle | 0.0226627 |
| CCDC122 | coiled-coil domain containing 122 | 0.0222633 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0221216 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0220344 |
| ANXA5 | annexin A5 | 0.0220027 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0218946 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.021808 |
| AHR | aryl hydrocarbon receptor | 0.0217488 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0216504 |
| MED13 | mediator complex subunit 13 | 0.0215437 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0214159 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.0214051 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0212341 |
| WWC2 | WW and C2 domain containing 2 | 0.0208704 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0207831 |
| FOXO3 | forkhead box O3 | 0.0204076 |
| FAM53C | family with sequence similarity 53, member C | 0.0201935 |
| CREBBP | CREB binding protein | 0.0201355 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0200323 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0198335 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0197904 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0197573 |
| SP100 | SP100 nuclear antigen | 0.019658 |
| ATG10 | autophagy related 10 | 0.0195158 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0194412 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0192414 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0192027 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0191709 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0191469 |
| FAM162A | family with sequence similarity 162, member A | 0.0189499 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0189446 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0188268 |
| RSPH3 | radial spoke 3 homolog (Chlamydomonas) | 0.0186089 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0181159 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0179609 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0179171 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0178921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155025 |
| VIM | vimentin | -0.13483 |
| TMSB10 | thymosin beta 10 | -0.116275 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0961656 |
| CD44 | CD44 molecule (Indian blood group) | -0.0923507 |
| PTMA | prothymosin, alpha | -0.086259 |
| EGR1 | early growth response 1 | -0.0760885 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0691521 |
| POTEF | POTE ankyrin domain family, member F | -0.063821 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0609269 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0605208 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0586613 |
| MAP1B | microtubule-associated protein 1B | -0.0565665 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0541612 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0521396 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0518122 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0516847 |
| FLNB | filamin B, beta | -0.0513077 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0508751 |
| DNER | delta/notch-like EGF repeat containing | -0.0497765 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0489637 |
| HMGA2 | high mobility group AT-hook 2 | -0.0489409 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0471764 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0466656 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0464305 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0462739 |
| PRR16 | proline rich 16 | -0.0462316 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0452074 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0449393 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0440008 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0439943 |
| NALCN | sodium leak channel, non selective | -0.0433384 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0431225 |
| PDE8A | phosphodiesterase 8A | -0.0424124 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0419157 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0416269 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0415468 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0408291 |
| B2M | beta-2-microglobulin | -0.0407558 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0403103 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0397822 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.038555 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.038451 |
| NAV2 | neuron navigator 2 | -0.038337 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0376844 |
| JUN | jun proto-oncogene | -0.0371732 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0369243 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0363496 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0359072 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0357965 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0356057 |
| SPAG9 | sperm associated antigen 9 | -0.0350654 |
| PYGL | phosphorylase, glycogen, liver | -0.0342417 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0342086 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0340309 |
| GNAS | GNAS complex locus | -0.0339897 |
| ATM | ATM serine/threonine kinase | -0.0336418 |
| UTRN | utrophin | -0.0335683 |
| KIAA1328 | KIAA1328 | -0.0335327 |
| PRKCA | protein kinase C, alpha | -0.0334585 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.033118 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0327607 |
| FMNL2 | formin-like 2 | -0.0326981 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0323125 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0321622 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0320443 |
| FMN1 | formin 1 | -0.0312813 |
| DST | dystonin | -0.0311297 |
| GOLGA2 | golgin A2 | -0.0306442 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0302803 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.029734 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0296081 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0292574 |
| GPC6 | glypican 6 | -0.0290737 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0286347 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0286245 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0285324 |
| RBM39 | RNA binding motif protein 39 | -0.0284562 |
| ATXN1 | ataxin 1 | -0.0283696 |
| EFNA5 | ephrin-A5 | -0.0283678 |
| NKTR | natural killer cell triggering receptor | -0.0281961 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0280096 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0277784 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0274842 |
| NDRG1 | N-myc downstream regulated 1 | -0.0274609 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0274246 |
| CFH | complement factor H | -0.0273203 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0272247 |
| IGF2 | insulin-like growth factor 2 | -0.0270305 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0269897 |
| MATR3 | matrin 3 | -0.0268496 |
| CUL3 | cullin 3 | -0.0264606 |
| S100A6 | S100 calcium binding protein A6 | -0.026404 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0263458 |
| LMO7 | LIM domain 7 | -0.0263217 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0262308 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0261303 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0260955 |
| ANXA2 | annexin A2 | -0.0260479 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0259609 |
