| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC2 | stanniocalcin 2 | 0.146148 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.123553 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102005 |
| PLIN2 | perilipin 2 | 0.0775753 |
| FAT1 | FAT atypical cadherin 1 | 0.0646053 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.057325 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0539612 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0528208 |
| ENO1 | enolase 1, (alpha) | 0.0518307 |
| MYOF | myoferlin | 0.0464284 |
| AHNAK | AHNAK nucleoprotein | 0.0452978 |
| TXNRD1 | thioredoxin reductase 1 | 0.0408685 |
| FAM13A | family with sequence similarity 13, member A | 0.0402673 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0396084 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0390868 |
| H1-0 | H1.0 linker histone | 0.038077 |
| GPC5 | glypican 5 | 0.037814 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0376388 |
| AHR | aryl hydrocarbon receptor | 0.0352972 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0347828 |
| DST | dystonin | 0.0342102 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0336631 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0334686 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.033397 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.032593 |
| ANXA5 | annexin A5 | 0.0314122 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0300592 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0297742 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0296377 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0295844 |
| FBN1 | fibrillin 1 | 0.0282915 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0282615 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0281053 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0277562 |
| DUSP6 | dual specificity phosphatase 6 | 0.0268676 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0261351 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0249622 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0242203 |
| XPO1 | exportin 1 | 0.0236729 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0217356 |
| FRMD5 | FERM domain containing 5 | 0.0213148 |
| FOSL1 | FOS-like antigen 1 | 0.0211114 |
| FLNA | filamin A, alpha | 0.0210615 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0210605 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0210416 |
| S100A10 | S100 calcium binding protein A10 | 0.0204402 |
| LYST | lysosomal trafficking regulator | 0.0200942 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0200898 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0200346 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0197336 |
| FRMD6 | FERM domain containing 6 | 0.0195486 |
| CFB | complement factor B | 0.0185512 |
| PGK1 | phosphoglycerate kinase 1 | 0.0184337 |
| HMGA2 | high mobility group AT-hook 2 | 0.0184301 |
| PRKCA | protein kinase C, alpha | 0.0180071 |
| SIRT1 | sirtuin 1 | 0.0179681 |
| RASAL2 | RAS protein activator like 2 | 0.0178962 |
| ZNF160 | zinc finger protein 160 | 0.0178123 |
| SEPTIN7 | septin 7 | 0.0177533 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0175857 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0174217 |
| EGFR | epidermal growth factor receptor | 0.0173356 |
| FMNL2 | formin-like 2 | 0.0173333 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0172534 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0169147 |
| LAMC2 | laminin, gamma 2 | 0.0168363 |
| FHIT | fragile histidine triad | 0.0165864 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0164594 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.016427 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0164022 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0161001 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0159419 |
| NOCT | nocturnin | 0.0157342 |
| VEGFA | vascular endothelial growth factor A | 0.0156282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0154729 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.015303 |
| OGA | O-GlcNAcase | 0.0152863 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0152444 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151957 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0150314 |
| FLNB | filamin B, beta | 0.0149509 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0148372 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0148289 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0147688 |
| CEP250 | centrosomal protein 250kDa | 0.01466 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.014605 |
| FAM107B | family with sequence similarity 107, member B | 0.0144167 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0144153 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0142284 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0141374 |
| RSF1 | remodeling and spacing factor 1 | 0.0140718 |
| ZNF217 | zinc finger protein 217 | 0.0140236 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0139363 |
| DENND5B | DENN/MADD domain containing 5B | 0.0139199 |
| RND3 | Rho family GTPase 3 | 0.0139186 |
| CCNT2 | cyclin T2 | 0.0138546 |
| SERTAD2 | SERTA domain containing 2 | 0.0137319 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0137009 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0136004 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0135464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.381345 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.128818 |
| FN1 | fibronectin 1 | -0.125779 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.11124 |
| ITGA1 | integrin, alpha 1 | -0.109714 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104695 |
| ASPH | aspartate beta-hydroxylase | -0.0984853 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.095476 |
| VCL | vinculin | -0.086537 |
| GLIS3 | GLIS family zinc finger 3 | -0.0851241 |
| MT2A | metallothionein 2A | -0.0718438 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0683814 |
| SYT1 | synaptotagmin I | -0.0670094 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0664985 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0630326 |
| EGR1 | early growth response 1 | -0.0627954 |
| HLA-B | major histocompatibility complex, class I, B | -0.0626265 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0622959 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0590007 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0577881 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0567342 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0565982 |
| PELO | pelota homolog (Drosophila) | -0.0556953 |
| PTMA | prothymosin, alpha | -0.0550154 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0543777 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.054166 |
| NRP1 | neuropilin 1 | -0.05375 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0537234 |
| CALU | calumenin | -0.0532474 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0532472 |
| COPA | coatomer protein complex, subunit alpha | -0.0524735 |
| FTL | ferritin, light polypeptide | -0.0499008 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0498968 |
| NTN4 | netrin 4 | -0.0495509 |
| TMSB10 | thymosin beta 10 | -0.0490996 |
| RBM39 | RNA binding motif protein 39 | -0.048309 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0478982 |
| B2M | beta-2-microglobulin | -0.0478943 |
| TXNIP | thioredoxin interacting protein | -0.0471096 |
| TOP1 | topoisomerase (DNA) I | -0.0466387 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0464965 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.046098 |
| SFTPA2 | surfactant protein A2 | -0.0460161 |
| VIM | vimentin | -0.0458796 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0457237 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0453955 |
| GNAS | GNAS complex locus | -0.0442633 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0430482 |
| RRBP1 | ribosome binding protein 1 | -0.0427477 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0423238 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0413837 |
| VMP1 | vacuole membrane protein 1 | -0.0400916 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0390084 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0388435 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0388362 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0386578 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380317 |
| CUL3 | cullin 3 | -0.0371334 |
| IER3 | immediate early response 3 | -0.0368321 |
| FNBP1 | formin binding protein 1 | -0.0362904 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.035442 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0352031 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0347864 |
| YBX3 | Y box binding protein 3 | -0.0346183 |
| MKI67 | marker of proliferation Ki-67 | -0.0345265 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0342874 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0341103 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.033941 |
| SMOX | spermine oxidase | -0.0335772 |
| CLINT1 | clathrin interactor 1 | -0.0334138 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0333505 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0333013 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.033266 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0331558 |
| CANX | calnexin | -0.0331554 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0331441 |
| YME1L1 | YME1-like 1 ATPase | -0.0330559 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0329588 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0325084 |
| KSR1 | kinase suppressor of ras 1 | -0.0324529 |
| KLF10 | Kruppel-like factor 10 | -0.0320278 |
| ACTN4 | actinin, alpha 4 | -0.0319978 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0319505 |
| SETD5 | SET domain containing 5 | -0.0317307 |
| SUCO | SUN domain containing ossification factor | -0.0315254 |
| SEC24A | SEC24 family member A | -0.0308236 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0301674 |
| SSH1 | slingshot protein phosphatase 1 | -0.0300333 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0299742 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0297995 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0297887 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296547 |
| RAB7A | RAB7A, member RAS oncogene family | -0.029611 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0295534 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0295447 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0295095 |
| GOLGA4 | golgin A4 | -0.0294569 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0293 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0292108 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0287894 |
