Hormone signaling Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description (Kyoto Encyclopedia of Genes and Genomes, hsa04081)
External Link https://www.kegg.jp/entry/hsa04081
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Genes

218 proteins participating in the Hormone signaling pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ACVR1 activin A receptor, type I
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AGXT alanine-glyoxylate aminotransferase
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AVPR1A arginine vasopressin receptor 1A
AVPR1B arginine vasopressin receptor 1B
AVPR2 arginine vasopressin receptor 2
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
C1QTNF1 C1q and tumor necrosis factor related protein 1
CALCA calcitonin-related polypeptide alpha
CALCB calcitonin-related polypeptide beta
CALCR calcitonin receptor
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CD200R1 CD200 receptor 1
CHGA chromogranin A
CLSTN1 calsyntenin 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSH2 chorionic somatomammotropin hormone 2
CSHL1 chorionic somatomammotropin hormone-like 1
DIDO1 death inducer-obliterator 1
DIO2 deiodinase, iodothyronine, type II
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EPOR erythropoietin receptor
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
GAST gastrin
GCG glucagon
GCGR glucagon receptor
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIPR gastric inhibitory polypeptide receptor
GLP1R glucagon-like peptide 1 receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GNRHR gonadotropin-releasing hormone receptor
GPER1 G protein-coupled estrogen receptor 1
GUCA2A guanylate cyclase activator 2A (guanylin)
GUCA2B guanylate cyclase activator 2B (uroguanylin)
GUCY2C guanylate cyclase 2C
HAMP hepcidin antimicrobial peptide
HCRT hypocretin (orexin) neuropeptide precursor
HCRTR1 hypocretin (orexin) receptor 1
HEPH hephaestin
HEPHL1 hephaestin-like 1
IAPP islet amyloid polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
INS insulin
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
LEP leptin
LEPROT leptin receptor overlapping transcript
LHB luteinizing hormone beta polypeptide
LHCGR luteinizing hormone/choriogonadotropin receptor
LNCEGFL7OS lncRNA EGFL7 opposite strand
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MC5R melanocortin 5 receptor
MCHR1 melanin-concentrating hormone receptor 1
MCHR2 melanin-concentrating hormone receptor 2
MLNR motilin receptor
MPL MPL proto-oncogene, thrombopoietin receptor
MRLN myoregulin
NANOS1 nanos homolog 1 (Drosophila)
NLRP3 NLR family, pyrin domain containing 3
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR1 natriuretic peptide receptor 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PDYN prodynorphin
PENK proenkephalin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCB4 phospholipase C, beta 4
PMCH pro-melanin-concentrating hormone
PNOC prepronociceptin
POMC proopiomelanocortin
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PRL prolactin
PRLH prolactin releasing hormone
PRLHR prolactin releasing hormone receptor
PRLR prolactin receptor
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTRH2 peptidyl-tRNA hydrolase 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RHOA ras homolog family member A
RIPK2 receptor-interacting serine-threonine kinase 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD9 SMAD family member 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
THPO thrombopoietin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
TSHB thyroid stimulating hormone, beta
TSHR thyroid stimulating hormone receptor
UCN urocortin
UCN2 urocortin 2
UCN3 urocortin 3
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2