Hrd1p ubiquitin ligase complex Gene Set

Dataset	GO Cellular Component Annotations 2025
Category	structural or functional annotations
Type	cellular component
Description	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. (Gene Ontology, GO_0000836)
External Link	http://amigo.geneontology.org/amigo/term/GO:0000836
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Genes

6 proteins localized to the Hrd1p ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol	Name
FAM8A1	family with sequence similarity 8, member A1
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin
SEL1L	sel-1 suppressor of lin-12-like (C. elegans)
SYVN1	synovial apoptosis inhibitor 1, synoviolin
UBE2J1	ubiquitin-conjugating enzyme E2, J1