Hs-445 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Non-Cancerous Tumour (Cell Model Passports, SIDM00668)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00668
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Genes

199 proteins associated with the cell line Hs-445 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACTA1 actin, alpha 1, skeletal muscle
ACTBL2 actin, beta-like 2
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ANXA6 annexin A6
ARHGAP17 Rho GTPase activating protein 17
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
BAX BCL2-associated X protein
BMP2K BMP2 inducible kinase
CAB39 calcium binding protein 39
CCDC50 coiled-coil domain containing 50
CHDH choline dehydrogenase
CHMP4A charged multivesicular body protein 4A
CMTR1 cap methyltransferase 1
CNTRL centriolin
CRYZ crystallin, zeta (quinone reductase)
CSK c-src tyrosine kinase
CTBP1 C-terminal binding protein 1
EHD4 EH-domain containing 4
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ETV6 ets variant 6
FAM117B family with sequence similarity 117, member B
FDPS farnesyl diphosphate synthase
FKBP5 FK506 binding protein 5
FNBP1 formin binding protein 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRHPR glyoxylate reductase/hydroxypyruvate reductase
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HVCN1 hydrogen voltage gated channel 1
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL4I1 interleukin 4 induced 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
LAP3 leucine aminopeptidase 3
LNPEP leucyl/cystinyl aminopeptidase
LOC101928572 uncharacterized LOC101928572
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLAL1 lysophospholipase-like 1
M6PR mannose-6-phosphate receptor (cation dependent)
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MCM10 minichromosome maintenance complex component 10
MDH1 malate dehydrogenase 1, NAD (soluble)
METTL16 methyltransferase like 16
MIR6812 microRNA 6812
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MX1 MX dynamin-like GTPase 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NEK9 NIMA-related kinase 9
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIBAN2 niban apoptosis regulator 2
NIT2 nitrilase family, member 2
NMI N-myc (and STAT) interactor
NT5DC1 5'-nucleotidase domain containing 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLS1 plastin 1
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB28 RAB28, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAN RAN, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RGS10 regulator of G-protein signaling 10
RNF32 ring finger protein 32
RPA1 replication protein A1, 70kDa
SART3 squamous cell carcinoma antigen recognized by T cells 3
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFXN3 sideroflexin 3
SNRPE small nuclear ribonucleoprotein polypeptide E
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK38L serine/threonine kinase 38 like
STK4 serine/threonine kinase 4
STX7 syntaxin 7
SUB1 SUB1 homolog (S. cerevisiae)
THOP1 thimet oligopeptidase 1
TKFC triokinase/FMN cyclase
TMSB4X thymosin beta 4, X-linked
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TRAFD1 TRAF-type zinc finger domain containing 1
TREX1 three prime repair exonuclease 1
TRIM22 tripartite motif containing 22
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
WASF2 WAS protein family, member 2

Symbol Name
AAK1 AP2 associated kinase 1
ACP2 acid phosphatase 2, lysosomal
ACTG1P22 actin gamma 1 pseudogene 22
ACYP2 acylphosphatase 2, muscle type
AKAP9 A kinase (PRKA) anchor protein 9
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
BCL2L1 BCL2-like 1
BCL7C B-cell CLL/lymphoma 7C
BZW2 basic leucine zipper and W2 domains 2
CAPN2 calpain 2, (m/II) large subunit
CCDC127 coiled-coil domain containing 127
CCDC134 coiled-coil domain containing 134
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPP centromere protein P
CIP2A cellular inhibitor of PP2A
CKS1B CDC28 protein kinase regulatory subunit 1B
CTH cystathionine gamma-lyase
CUX1 cut-like homeobox 1
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DNAH6 dynein, axonemal, heavy chain 6
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
ERLIN1 ER lipid raft associated 1
EXD2 exonuclease 3'-5' domain containing 2
FAM184B family with sequence similarity 184, member B
FKBP9 FK506 binding protein 9, 63 kDa
FKBPL FK506 binding protein like
GBA glucosidase, beta, acid
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GK glycerol kinase
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2B integral membrane protein 2B
JAK1 Janus kinase 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF14 kinesin family member 14
KIF1BP KIF1 binding protein
KIF4A kinesin family member 4A
KMT2A lysine (K)-specific methyltransferase 2A
LARP4 La ribonucleoprotein domain family, member 4
LOC100131795 uncharacterized LOC100131795
LONP2 lon peptidase 2, peroxisomal
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC59 leucine rich repeat containing 59
LYN LYN proto-oncogene, Src family tyrosine kinase
MED13 mediator complex subunit 13
MFF mitochondrial fission factor
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGST2 microsomal glutathione S-transferase 2
MOCS1 molybdenum cofactor synthesis 1
MPRIP myosin phosphatase Rho interacting protein
MTFR1 mitochondrial fission regulator 1
MYH10 myosin, heavy chain 10, non-muscle
NBAS neuroblastoma amplified sequence
NCAPG2 non-SMC condensin II complex, subunit G2
NDC80 NDC80 kinetochore complex component
NFX1 nuclear transcription factor, X-box binding 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NPTN neuroplastin
NRP2 neuropilin 2
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PIR pirin (iron-binding nuclear protein)
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRRC2B proline-rich coiled-coil 2B
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
RAB22A RAB22A, member RAS oncogene family
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RNF25 ring finger protein 25
RRBP1 ribosome binding protein 1
RTN4 reticulon 4
SELENOS selenoprotein S
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35F6 solute carrier family 35, member F6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX29 sorting nexin 29
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPNS1 spinster homolog 1 (Drosophila)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TFB2M transcription factor B2, mitochondrial
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM201 transmembrane protein 201
TMEM63A transmembrane protein 63A
TMEM87A transmembrane protein 87A
TMOD2 tropomodulin 2 (neuronal)
TPPP tubulin polymerization promoting protein
TXN2 thioredoxin 2
TXNIP thioredoxin interacting protein
UBAP1 ubiquitin associated protein 1
UBE4B ubiquitination factor E4B
UTRN utrophin
YPEL5 yippee-like 5 (Drosophila)
ZNF106 zinc finger protein 106
ZNF148 zinc finger protein 148