Huntington's Disease_Brain_GSE3621 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3621
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Genes

600 genes differentially expressed during Huntington's Disease_Brain_GSE3621 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
FAHD2B fumarylacetoacetate hydrolase domain containing 2B 3.75344
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 3.67685
HACD1 3-hydroxyacyl-CoA dehydratase 1 3.20415
UBA2 ubiquitin-like modifier activating enzyme 2 3.14508
DCAF11 DDB1 and CUL4 associated factor 11 3.12767
SMAD1 SMAD family member 1 3.02587
SEPHS1 selenophosphate synthetase 1 2.93328
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.92273
ARMC8 armadillo repeat containing 8 2.90491
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 2.85389
FKBP9 FK506 binding protein 9, 63 kDa 2.84625
EPC2 enhancer of polycomb homolog 2 (Drosophila) 2.78583
MKRN2 makorin ring finger protein 2 2.70024
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 2.69633
TRNAU1AP tRNA selenocysteine 1 associated protein 1 2.67125
ANAPC5 anaphase promoting complex subunit 5 2.63613
CLCN3 chloride channel, voltage-sensitive 3 2.62458
CHM choroideremia (Rab escort protein 1) 2.57003
ATRAID all-trans retinoic acid-induced differentiation factor 2.56454
TMEM165 transmembrane protein 165 2.54834
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.54131
GTF2B general transcription factor IIB 2.51612
NGLY1 N-glycanase 1 2.49306
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.48343
COMMD3-BMI1 COMMD3-BMI1 readthrough 2.48041
C6ORF62 chromosome 6 open reading frame 62 2.47137
PEX11A peroxisomal biogenesis factor 11 alpha 2.46972
PPP6C protein phosphatase 6, catalytic subunit 2.45987
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 2.4525
H2AFY H2A histone family, member Y 2.42792
STX12 syntaxin 12 2.42035
SLC35E3 solute carrier family 35, member E3 2.41568
MRPL39 mitochondrial ribosomal protein L39 2.41173
HNRNPR heterogeneous nuclear ribonucleoprotein R 2.39715
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.37645
MORF4L2 mortality factor 4 like 2 2.37456
CHMP2B charged multivesicular body protein 2B 2.3498
ACAT1 acetyl-CoA acetyltransferase 1 2.34955
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.28505
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.27228
RBM22 RNA binding motif protein 22 2.27209
RP9 retinitis pigmentosa 9 (autosomal dominant) 2.2614
C8ORF59 chromosome 8 open reading frame 59 2.25825
LYRM2 LYR motif containing 2 2.24843
ZNF790 zinc finger protein 790 2.23939
TMX1 thioredoxin-related transmembrane protein 1 2.22241
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 2.20931
SRP72 signal recognition particle 72kDa 2.1947
KIAA0196 KIAA0196 2.19388
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 2.19363
SAP18 Sin3A-associated protein, 18kDa 2.18916
NRIP2 nuclear receptor interacting protein 2 2.18624
BSDC1 BSD domain containing 1 2.18314
PARP12 poly (ADP-ribose) polymerase family, member 12 2.18235
SMOC1 SPARC related modular calcium binding 1 2.17624
NECAP1 NECAP endocytosis associated 1 2.16992
OTUD7B OTU deubiquitinase 7B 2.16336
KIAA0368 KIAA0368 2.1486
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.14423
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.13021
PNMA2 paraneoplastic Ma antigen 2 2.12551
SLC30A7 solute carrier family 30 (zinc transporter), member 7 2.10448
EEF2 eukaryotic translation elongation factor 2 2.10153
EHBP1 EH domain binding protein 1 2.09905
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 2.09189
OAT ornithine aminotransferase 2.07094
HEXIM1 hexamethylene bis-acetamide inducible 1 2.0641
ELOVL2 ELOVL fatty acid elongase 2 2.05008
FLOT2 flotillin 2 2.04597
NALCN sodium leak channel, non selective 2.02885
MDP1 magnesium-dependent phosphatase 1 1.99312
RPL7L1 ribosomal protein L7-like 1 1.99178
SIN3B SIN3 transcription regulator family member B 1.97997
M6PR mannose-6-phosphate receptor (cation dependent) 1.97821
MCL1 myeloid cell leukemia 1 1.97541
UBXN4 UBX domain protein 4 1.96369
MSRB2 methionine sulfoxide reductase B2 1.96197
SNAPIN SNAP-associated protein 1.94647
IMPAD1 inositol monophosphatase domain containing 1 1.94266
NPAT nuclear protein, ataxia-telangiectasia locus 1.94145
TPRG1L tumor protein p63 regulated 1-like 1.93509
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.9323
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.92914
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 1.92501
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.91911
KIAA1551 KIAA1551 1.91795
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1.9165
ANAPC2 anaphase promoting complex subunit 2 1.91536
TCF25 transcription factor 25 (basic helix-loop-helix) 1.90796
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 1.89468
POLR1C polymerase (RNA) I polypeptide C, 30kDa 1.8866
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.87655
FTL ferritin, light polypeptide 1.87577
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.86783
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 1.86703
RAB1B RAB1B, member RAS oncogene family 1.86434
TRIM35 tripartite motif containing 35 1.86382
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.86139
ENSA endosulfine alpha 1.85369
NOP56 NOP56 ribonucleoprotein 1.84468
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.84434
ABT1 activator of basal transcription 1 1.84188
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.84065
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 1.83815
FAM98B family with sequence similarity 98, member B 1.83427
FBL fibrillarin 1.83305
OGFR opioid growth factor receptor 1.82547
SLC30A5 solute carrier family 30 (zinc transporter), member 5 1.82231
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.81896
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.81074
FXYD6 FXYD domain containing ion transport regulator 6 1.80925
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.80506
TOR1AIP2 torsin A interacting protein 2 1.80272
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 1.80241
SLC37A3 solute carrier family 37, member 3 1.79966
COMMD8 COMM domain containing 8 1.78537
ZMYM2 zinc finger, MYM-type 2 1.78344
UNC119 unc-119 homolog (C. elegans) 1.77575
ZNF878 zinc finger protein 878 1.77262
SRSF6 serine/arginine-rich splicing factor 6 1.77227
CTSZ cathepsin Z 1.77118
LMBRD1 LMBR1 domain containing 1 1.76745
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.75811
SNX24 sorting nexin 24 1.75235
ILK integrin-linked kinase 1.75084
C17ORF100 chromosome 17 open reading frame 100 1.75041
NPR2 natriuretic peptide receptor 2 1.7498
PDLIM5 PDZ and LIM domain 5 1.74966
SPTSSA serine palmitoyltransferase, small subunit A 1.74583
RSBN1 round spermatid basic protein 1 1.74516
SCRN1 secernin 1 1.74309
PCNP PEST proteolytic signal containing nuclear protein 1.73671
ZNF606 zinc finger protein 606 1.73118
ECI2 enoyl-CoA delta isomerase 2 1.73038
CHMP2A charged multivesicular body protein 2A 1.72795
MKRN1 makorin ring finger protein 1 1.72781
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 1.7239
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.71923
TRUB2 TruB pseudouridine (psi) synthase family member 2 1.71762
FAF1 Fas (TNFRSF6) associated factor 1 1.70824
FAM8A1 family with sequence similarity 8, member A1 1.70614
RGS19 regulator of G-protein signaling 19 1.69555
RNF26 ring finger protein 26 1.69464
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.69158
FAIM Fas apoptotic inhibitory molecule 1.68799
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 1.68651
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.68629
TMEM192 transmembrane protein 192 1.6825
TMEM183A transmembrane protein 183A 1.68179
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 1.68149
SKAP2 src kinase associated phosphoprotein 2 1.67908
PRDX1 peroxiredoxin 1 1.67731
SREBF1 sterol regulatory element binding transcription factor 1 1.67391
GUSB glucuronidase, beta 1.67291
CLCC1 chloride channel CLIC-like 1 1.67134
STX18 syntaxin 18 1.67104
TMEM185A transmembrane protein 185A 1.67003
TAPT1 transmembrane anterior posterior transformation 1 1.66408
GOLGA7 golgin A7 1.6636
FLYWCH2 FLYWCH family member 2 1.66215
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.65983
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 1.65823
GRN granulin 1.65611
SPAST spastin 1.65594
CETN2 centrin, EF-hand protein, 2 1.65568
ZNF250 zinc finger protein 250 1.65433
GLG1 golgi glycoprotein 1 1.65375
DGCR2 DiGeorge syndrome critical region gene 2 1.65328
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 1.65203
PEX6 peroxisomal biogenesis factor 6 1.6518
SEC23B Sec23 homolog B (S. cerevisiae) 1.65046
CSDE1 cold shock domain containing E1, RNA-binding 1.64844
USP34 ubiquitin specific peptidase 34 1.64155
SHARPIN SHANK-associated RH domain interactor 1.63808
STAU1 staufen double-stranded RNA binding protein 1 1.63807
C19ORF43 chromosome 19 open reading frame 43 1.63736
PPDPF pancreatic progenitor cell differentiation and proliferation factor 1.6336
RRAGC Ras-related GTP binding C 1.63225
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.62603
MANBA mannosidase, beta A, lysosomal 1.62411
RNF217 ring finger protein 217 1.62207
OSBPL11 oxysterol binding protein-like 11 1.62057
TIPRL TOR signaling pathway regulator 1.62037
DCTN2 dynactin 2 (p50) 1.61824
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.61709
HBP1 HMG-box transcription factor 1 1.61677
DBNL drebrin-like 1.61627
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.61089
NUP93 nucleoporin 93kDa 1.6087
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.60803
GRK6 G protein-coupled receptor kinase 6 1.60014
ING3 inhibitor of growth family, member 3 1.59985
RFWD3 ring finger and WD repeat domain 3 1.59685
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.59421
RAB2B RAB2B, member RAS oncogene family 1.58673
MACROD1 MACRO domain containing 1 1.58602
MTMR9 myotubularin related protein 9 1.58246
WIPF1 WAS/WASL interacting protein family, member 1 1.58193
INTS5 integrator complex subunit 5 1.57266
USP24 ubiquitin specific peptidase 24 1.57093
TMX3 thioredoxin-related transmembrane protein 3 1.5693
BCL10 B-cell CLL/lymphoma 10 1.56201
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.55928
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.55748
TJP2 tight junction protein 2 1.55713
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.55354
USP48 ubiquitin specific peptidase 48 1.55155
SH3GLB1 SH3-domain GRB2-like endophilin B1 1.55103
LARP4B La ribonucleoprotein domain family, member 4B 1.55079
GABPA GA binding protein transcription factor, alpha subunit 60kDa 1.54947
IWS1 IWS1 homolog (S. cerevisiae) 1.54733
RALBP1 ralA binding protein 1 1.54488
HAGH hydroxyacylglutathione hydrolase 1.54438
CBX4 chromobox homolog 4 1.54418
BAG2 BCL2-associated athanogene 2 1.54398
SRSF4 serine/arginine-rich splicing factor 4 1.54352
ORC3 origin recognition complex, subunit 3 1.5422
KLHL24 kelch-like family member 24 1.54156
BIRC2 baculoviral IAP repeat containing 2 1.54152
NEK9 NIMA-related kinase 9 1.5413
PCSK7 proprotein convertase subtilisin/kexin type 7 1.54099
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.54039
TSPAN3 tetraspanin 3 1.53917
FNTA farnesyltransferase, CAAX box, alpha 1.53903
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 1.53518
ACOT9 acyl-CoA thioesterase 9 1.53495
TCERG1 transcription elongation regulator 1 1.53463
TRAPPC8 trafficking protein particle complex 8 1.53451
ZSWIM7 zinc finger, SWIM-type containing 7 1.53393
BRD3 bromodomain containing 3 1.53368
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.53363
RNF113A ring finger protein 113A 1.53227
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.53184
RAP1A RAP1A, member of RAS oncogene family 1.53007
RPL27 ribosomal protein L27 1.52879
PDPN podoplanin 1.52875
ACBD3 acyl-CoA binding domain containing 3 1.52634
IER3IP1 immediate early response 3 interacting protein 1 1.52503
BAHCC1 BAH domain and coiled-coil containing 1 1.52419
NOL11 nucleolar protein 11 1.52391
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.52232
MRPS17 mitochondrial ribosomal protein S17 1.5192
CAPN2 calpain 2, (m/II) large subunit 1.51652
RDX radixin 1.51447
MIER3 mesoderm induction early response 1, family member 3 1.51429
FAM76B family with sequence similarity 76, member B 1.51418
ZNF22 zinc finger protein 22 1.51417
DENND5A DENN/MADD domain containing 5A 1.50882
NCOA2 nuclear receptor coactivator 2 1.50874
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 1.50713
TTC28 tetratricopeptide repeat domain 28 1.50407
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 1.50324
SUMF1 sulfatase modifying factor 1 1.50322
ZDHHC16 zinc finger, DHHC-type containing 16 1.50272
PRKCQ protein kinase C, theta 1.49559
BGN biglycan 1.49533
NCOA4 nuclear receptor coactivator 4 1.49309
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.49148
KLHL9 kelch-like family member 9 1.48906
ITM2A integral membrane protein 2A 1.48892
CARM1 coactivator-associated arginine methyltransferase 1 1.48697
NAMPT nicotinamide phosphoribosyltransferase 1.48585
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.48509
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.48472
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 1.48028
GSPT2 G1 to S phase transition 2 1.47857
USP11 ubiquitin specific peptidase 11 1.47819
PSAT1 phosphoserine aminotransferase 1 1.47553
RPS20 ribosomal protein S20 1.47545
CSNK1D casein kinase 1, delta 1.47469
C1QBP complement component 1, q subcomponent binding protein 1.47455
RGMB repulsive guidance molecule family member b 1.47365
ZNF655 zinc finger protein 655 1.47088
EI24 etoposide induced 2.4 1.46994
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 1.4691
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 1.46796
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 1.4678
PHYH phytanoyl-CoA 2-hydroxylase 1.46535
FBXO25 F-box protein 25 1.46186
SON SON DNA binding protein 1.46108
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 1.45957
PRRC2B proline-rich coiled-coil 2B 1.45936
HECA headcase homolog (Drosophila) 1.45923
FBXL2 F-box and leucine-rich repeat protein 2 1.45668
PQBP1 polyglutamine binding protein 1 1.45422
GPATCH8 G patch domain containing 8 1.45374
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.45214
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18 1.44778
TMEM126A transmembrane protein 126A 1.44644
GSPT1 G1 to S phase transition 1 1.44573
USP22 ubiquitin specific peptidase 22 1.44541
CSTB cystatin B (stefin B) 1.44454
GNG10 guanine nucleotide binding protein (G protein), gamma 10 1.44189
TMEM55A transmembrane protein 55A 1.44001
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 1.43964
KLHDC10 kelch domain containing 10 1.43842
MEGF8 multiple EGF-like-domains 8 1.43524
MTPAP mitochondrial poly(A) polymerase 1.43464
RUFY3 RUN and FYVE domain containing 3 1.43457
RNF25 ring finger protein 25 1.43327

decreased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II -3.7328
OSBPL1A oxysterol binding protein-like 1A -3.49891
PCP4 Purkinje cell protein 4 -3.22311
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.95757
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.92474
ASPA aspartoacylase -2.90995
NRN1 neuritin 1 -2.90577
FGF12 fibroblast growth factor 12 -2.8471
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -2.82891
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -2.82372
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.72085
TPPP tubulin polymerization promoting protein -2.71745
QDPR quinoid dihydropteridine reductase -2.70436
AHCYL1 adenosylhomocysteinase-like 1 -2.69971
BHLHE40 basic helix-loop-helix family, member e40 -2.67367
CSDC2 cold shock domain containing C2, RNA binding -2.66091
SEPT5 septin 5 -2.641
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -2.62405
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -2.59899
RGS4 regulator of G-protein signaling 4 -2.57569
DPY19L1 dpy-19-like 1 (C. elegans) -2.56597
ALDOC aldolase C, fructose-bisphosphate -2.50989
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha -2.4776
MAL mal, T-cell differentiation protein -2.47682
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -2.47355
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -2.45056
PENK proenkephalin -2.43448
PMM1 phosphomannomutase 1 -2.41288
DDIT4L DNA-damage-inducible transcript 4-like -2.38074
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -2.33811
RBBP7 retinoblastoma binding protein 7 -2.32313
TTYH1 tweety family member 1 -2.32048
LGI1 leucine-rich, glioma inactivated 1 -2.31598
LMO4 LIM domain only 4 -2.29377
TSPAN2 tetraspanin 2 -2.27654
NTM neurotrimin -2.27069
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 -2.26057
STMN4 stathmin-like 4 -2.25347
SPARCL1 SPARC-like 1 (hevin) -2.25067
PITPNA phosphatidylinositol transfer protein, alpha -2.23996
DESI1 desumoylating isopeptidase 1 -2.23834
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -2.22954
ORAI2 ORAI calcium release-activated calcium modulator 2 -2.22867
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -2.21978
SYNE1 spectrin repeat containing, nuclear envelope 1 -2.20991
MAP2K4 mitogen-activated protein kinase kinase 4 -2.20191
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -2.17908
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -2.17432
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -2.16366
GLUL glutamate-ammonia ligase -2.15992
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -2.15014
DCLK1 doublecortin-like kinase 1 -2.13574
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.13012
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.11899
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -2.10974
PRKCG protein kinase C, gamma -2.10058
NDRG2 NDRG family member 2 -2.09758
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -2.09584
CALR calreticulin -2.08697
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -2.07972
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -2.07466
HTRA1 HtrA serine peptidase 1 -2.0739
STARD10 StAR-related lipid transfer (START) domain containing 10 -2.07312
TMEM132A transmembrane protein 132A -2.07027
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B -2.07015
SEC14L1 SEC14-like 1 (S. cerevisiae) -2.06785
MFGE8 milk fat globule-EGF factor 8 protein -2.05059
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -2.0471
RHBDL3 rhomboid, veinlet-like 3 (Drosophila) -2.04367
RGS7 regulator of G-protein signaling 7 -2.0366
TPP1 tripeptidyl peptidase I -2.03414
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -2.03194
CCNI cyclin I -2.01254
FASN fatty acid synthase -2.00817
DIO2 deiodinase, iodothyronine, type II -2.00691
LINGO1 leucine rich repeat and Ig domain containing 1 -1.99941
SQLE squalene epoxidase -1.99923
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.99688
CLSTN2 calsyntenin 2 -1.99384
C9ORF16 chromosome 9 open reading frame 16 -1.99362
TSPAN13 tetraspanin 13 -1.98268
MYEOV2 myeloma overexpressed 2 -1.98248
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -1.97087
CA11 carbonic anhydrase XI -1.96577
CTXN1 cortexin 1 -1.9655
LYNX1 Ly6/neurotoxin 1 -1.96153
CHN1 chimerin 1 -1.95918
KRT222 keratin 222, type II -1.95825
HOMER1 homer scaffolding protein 1 -1.94335
NT5DC3 5'-nucleotidase domain containing 3 -1.93422
RTN4RL1 reticulon 4 receptor-like 1 -1.92857
ENO2 enolase 2 (gamma, neuronal) -1.92686
CKB creatine kinase, brain -1.92394
NAT8L N-acetyltransferase 8-like (GCN5-related, putative) -1.91836
SV2B synaptic vesicle glycoprotein 2B -1.91125
CADM4 cell adhesion molecule 4 -1.91051
ACSL3 acyl-CoA synthetase long-chain family member 3 -1.90631
KIF3C kinesin family member 3C -1.87364
DUSP14 dual specificity phosphatase 14 -1.87139
HLF hepatic leukemia factor -1.87115
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -1.8699
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.86864
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like -1.86666
SOCS5 suppressor of cytokine signaling 5 -1.86018
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -1.85653
VSNL1 visinin-like 1 -1.85516
MIEN1 migration and invasion enhancer 1 -1.84267
PPP1R3C protein phosphatase 1, regulatory subunit 3C -1.83805
GLUD1 glutamate dehydrogenase 1 -1.83493
VIP vasoactive intestinal peptide -1.83438
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -1.83047
CLDN10 claudin 10 -1.83021
SCN4B sodium channel, voltage gated, type IV beta subunit -1.829
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.8267
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -1.8234
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -1.82009
GRM3 glutamate receptor, metabotropic 3 -1.81001
IGFBP5 insulin-like growth factor binding protein 5 -1.80756
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -1.80382
SYT7 synaptotagmin VII -1.80381
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.80285
CHGB chromogranin B -1.79666
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -1.78804
NDRG3 NDRG family member 3 -1.771
IL33 interleukin 33 -1.76997
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -1.76836
RAP1GAP RAP1 GTPase activating protein -1.76811
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -1.76722
SYT1 synaptotagmin I -1.76413
ASRGL1 asparaginase like 1 -1.74642
ITPKA inositol-trisphosphate 3-kinase A -1.74158
IQSEC3 IQ motif and Sec7 domain 3 -1.7413
ARRB1 arrestin, beta 1 -1.72741
SEPT11 septin 11 -1.71997
PDE7B phosphodiesterase 7B -1.71279
KIAA1107 KIAA1107 -1.71023
CRHBP corticotropin releasing hormone binding protein -1.70739
C11ORF87 chromosome 11 open reading frame 87 -1.7035
RHOBTB2 Rho-related BTB domain containing 2 -1.70344
CLU clusterin -1.69298
EMC6 ER membrane protein complex subunit 6 -1.68501
PPAP2B phosphatidic acid phosphatase type 2B -1.67882
NPTX1 neuronal pentraxin I -1.67507
TYRO3 TYRO3 protein tyrosine kinase -1.66575
PMVK phosphomevalonate kinase -1.66296
B3GNT1 -1.65978
PMCH pro-melanin-concentrating hormone -1.65837
DUSP7 dual specificity phosphatase 7 -1.65387
BAIAP2 BAI1-associated protein 2 -1.64972
SCN2A sodium channel, voltage gated, type II alpha subunit -1.64644
YEATS2 YEATS domain containing 2 -1.64399
SNW1 SNW domain containing 1 -1.64058
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.63957
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 -1.6372
C1QL2 complement component 1, q subcomponent-like 2 -1.6365
DNM1 dynamin 1 -1.63587
SH3GLB2 SH3-domain GRB2-like endophilin B2 -1.63485
SHISA5 shisa family member 5 -1.63298
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -1.62954
SORT1 sortilin 1 -1.62807
CNTN4 contactin 4 -1.62083
RGS7BP regulator of G-protein signaling 7 binding protein -1.61966
MCTS1 malignant T cell amplified sequence 1 -1.61821
DLG4 discs, large homolog 4 (Drosophila) -1.61536
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 -1.61382
ISYNA1 inositol-3-phosphate synthase 1 -1.61328
STAU2 staufen double-stranded RNA binding protein 2 -1.60664
MBP myelin basic protein -1.60632
TBC1D30 TBC1 domain family, member 30 -1.60439
KCNIP4 Kv channel interacting protein 4 -1.60371
ABLIM2 actin binding LIM protein family, member 2 -1.60353
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 -1.60266
EMC3 ER membrane protein complex subunit 3 -1.60081
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) -1.59964
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -1.59917
TRIM37 tripartite motif containing 37 -1.59893
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -1.59528
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.59238
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.5866
AKT3 v-akt murine thymoma viral oncogene homolog 3 -1.58032
ODF2 outer dense fiber of sperm tails 2 -1.58016
ZMYND8 zinc finger, MYND-type containing 8 -1.57258
ROGDI rogdi homolog (Drosophila) -1.56827
DPCD deleted in primary ciliary dyskinesia homolog (mouse) -1.55764
C8ORF46 chromosome 8 open reading frame 46 -1.55716
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -1.55566
FAM101B family with sequence similarity 101, member B -1.55474
SUN1 Sad1 and UNC84 domain containing 1 -1.55466
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.5542
RPH3A rabphilin 3A -1.55127
YPEL3 yippee-like 3 (Drosophila) -1.54988
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -1.54794
CDK19 cyclin-dependent kinase 19 -1.53951
RASL10A RAS-like, family 10, member A -1.53776
PARM1 prostate androgen-regulated mucin-like protein 1 -1.53681
MED9 mediator complex subunit 9 -1.53633
PDE10A phosphodiesterase 10A -1.53528
RASGEF1A RasGEF domain family, member 1A -1.53277
CSRP1 cysteine and glycine-rich protein 1 -1.52785
SST somatostatin -1.5176
TSPAN5 tetraspanin 5 -1.51541
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.51242
RAP1GAP2 RAP1 GTPase activating protein 2 -1.51194
PFKM phosphofructokinase, muscle -1.50799
NRCAM neuronal cell adhesion molecule -1.5055
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.50519
GRAMD3 GRAM domain containing 3 -1.50447
FGFR3 fibroblast growth factor receptor 3 -1.49867
LIN7B lin-7 homolog B (C. elegans) -1.4955
TESC tescalcin -1.4951
RTN4R reticulon 4 receptor -1.49384
LDHA lactate dehydrogenase A -1.4924
MRPS33 mitochondrial ribosomal protein S33 -1.49147
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.48793
CCDC3 coiled-coil domain containing 3 -1.48767
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -1.48756
OLFM1 olfactomedin 1 -1.48269
CXCL14 chemokine (C-X-C motif) ligand 14 -1.47802
VSTM2L V-set and transmembrane domain containing 2 like -1.47666
ARFIP2 ADP-ribosylation factor interacting protein 2 -1.47664
SCD stearoyl-CoA desaturase (delta-9-desaturase) -1.47571
SERTM1 serine-rich and transmembrane domain containing 1 -1.47492
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.47171
DDN dendrin -1.47075
CYB5R4 cytochrome b5 reductase 4 -1.46708
GPR162 G protein-coupled receptor 162 -1.46439
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.45421
YPEL2 yippee-like 2 (Drosophila) -1.45015
SFSWAP splicing factor, suppressor of white-apricot family -1.44424
NFX1 nuclear transcription factor, X-box binding 1 -1.44389
RGS16 regulator of G-protein signaling 16 -1.44246
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -1.43801
FGF13 fibroblast growth factor 13 -1.43556
RAB27B RAB27B, member RAS oncogene family -1.43446
METTL17 methyltransferase like 17 -1.43419
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.43363
STAC2 SH3 and cysteine rich domain 2 -1.43179
LRRK2 leucine-rich repeat kinase 2 -1.42952
CPSF3L cleavage and polyadenylation specific factor 3-like -1.42937
FAM189B family with sequence similarity 189, member B -1.42806
C8ORF34 chromosome 8 open reading frame 34 -1.42563
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.4237
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -1.42297
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -1.42114
GJA1 gap junction protein, alpha 1, 43kDa -1.4198
CHGA chromogranin A -1.4161
THY1 Thy-1 cell surface antigen -1.41597
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -1.41549
PDE1B phosphodiesterase 1B, calmodulin-dependent -1.41541
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -1.41538
PDE8B phosphodiesterase 8B -1.41384
LYPD6B LY6/PLAUR domain containing 6B -1.41049
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -1.40774
PRADC1 protease-associated domain containing 1 -1.4055
DAAM2 dishevelled associated activator of morphogenesis 2 -1.40433
DVL1 dishevelled segment polarity protein 1 -1.40161
CLCN2 chloride channel, voltage-sensitive 2 -1.40149
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -1.40043
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta -1.3991
FADS2 fatty acid desaturase 2 -1.3969
RASD1 RAS, dexamethasone-induced 1 -1.395
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.39392
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.39268
LITAF lipopolysaccharide-induced TNF factor -1.38678
PSD pleckstrin and Sec7 domain containing -1.38545
ADORA2A adenosine A2a receptor -1.3854
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.38523
CA7 carbonic anhydrase VII -1.38265
COPS7B COP9 signalosome subunit 7B -1.37775
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.37753
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -1.37262
SEPT3 septin 3 -1.37103
CPEB4 cytoplasmic polyadenylation element binding protein 4 -1.37014
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -1.36959
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -1.36553
SYT13 synaptotagmin XIII -1.36489
KIAA1324 KIAA1324 -1.36394
KIAA1045 KIAA1045 -1.35944
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -1.35697
RASL10B RAS-like, family 10, member B -1.35308
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 -1.35042
SUGP2 SURP and G patch domain containing 2 -1.3472
BOK BCL2-related ovarian killer -1.34509
PGBD5 piggyBac transposable element derived 5 -1.3416
BTBD10 BTB (POZ) domain containing 10 -1.34035
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -1.33921
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -1.3389
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.33604
CARKD carbohydrate kinase domain containing -1.33487
MYO5A myosin VA (heavy chain 12, myoxin) -1.33436
NXPH1 neurexophilin 1 -1.33416
SYBU syntabulin (syntaxin-interacting) -1.32592
COASY CoA synthase -1.32541
KCTD12 potassium channel tetramerization domain containing 12 -1.32276
TCP1 t-complex 1 -1.32157
MCHR1 melanin-concentrating hormone receptor 1 -1.3207
PLXND1 plexin D1 -1.31972
RAB40C RAB40C, member RAS oncogene family -1.31668
DAAM1 dishevelled associated activator of morphogenesis 1 -1.31649
ADAP1 ArfGAP with dual PH domains 1 -1.31528