Huntington's Disease_CNS - Brain (MMHCC)_GSE857 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE857
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Genes

600 genes differentially expressed during Huntington's Disease_CNS - Brain (MMHCC)_GSE857 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 5.16887
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 4.45476
IFITM3 interferon induced transmembrane protein 3 4.42106
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.95095
TM7SF3 transmembrane 7 superfamily member 3 3.30987
COL1A1 collagen, type I, alpha 1 3.29975
PACRGL PARK2 co-regulated-like 3.26315
SF3B3 splicing factor 3b, subunit 3, 130kDa 3.25925
MED20 mediator complex subunit 20 3.07711
CCT2 chaperonin containing TCP1, subunit 2 (beta) 3.05394
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.99957
SLC25A39 solute carrier family 25, member 39 2.99771
C17ORF62 chromosome 17 open reading frame 62 2.95656
CBR1 carbonyl reductase 1 2.86945
ATAD2B ATPase family, AAA domain containing 2B 2.80724
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 2.71033
USP25 ubiquitin specific peptidase 25 2.70141
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.68339
FAM46A family with sequence similarity 46, member A 2.67355
MTCH2 mitochondrial carrier 2 2.6359
MXI1 MAX interactor 1, dimerization protein 2.59862
RPIA ribose 5-phosphate isomerase A 2.59318
HEMGN hemogen 2.52809
NFYA nuclear transcription factor Y, alpha 2.4684
GAS8 growth arrest-specific 8 2.46337
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 2.45523
PTPRO protein tyrosine phosphatase, receptor type, O 2.4504
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 2.39863
STX7 syntaxin 7 2.37458
CHMP7 charged multivesicular body protein 7 2.34258
NOP16 NOP16 nucleolar protein 2.32559
PCBP1 poly(rC) binding protein 1 2.31268
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 2.30371
SNX9 sorting nexin 9 2.29351
CETN2 centrin, EF-hand protein, 2 2.28182
MTM1 myotubularin 1 2.28131
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.27502
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.27446
UTF1 undifferentiated embryonic cell transcription factor 1 2.19191
FIGNL1 fidgetin-like 1 2.16575
MRPL33 mitochondrial ribosomal protein L33 2.15664
SNX1 sorting nexin 1 2.14358
CENPC centromere protein C 2.14134
ZNF322 zinc finger protein 322 2.11442
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.09914
INTS4 integrator complex subunit 4 2.07866
BCL3 B-cell CLL/lymphoma 3 2.07746
C2ORF49 chromosome 2 open reading frame 49 2.07362
GP9 glycoprotein IX (platelet) 2.06992
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.06382
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.05412
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.05236
KHDC1L KH homology domain containing 1-like 2.03646
ILK integrin-linked kinase 2.01942
SART1 squamous cell carcinoma antigen recognized by T cells 2.01651
GOLGA4 golgin A4 1.98844
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.98261
MPG N-methylpurine-DNA glycosylase 1.96402
SIX1 SIX homeobox 1 1.95793
ROMO1 reactive oxygen species modulator 1 1.90941
RAB31 RAB31, member RAS oncogene family 1.88964
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.87265
TMEM5 transmembrane protein 5 1.86611
CENPL centromere protein L 1.86255
HINT1 histidine triad nucleotide binding protein 1 1.85768
GBP7 guanylate binding protein 7 1.85048
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 1.84585
TM9SF3 transmembrane 9 superfamily member 3 1.83576
SUMF1 sulfatase modifying factor 1 1.83018
SFXN1 sideroflexin 1 1.82861
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.81721
CEP350 centrosomal protein 350kDa 1.80442
PELI1 pellino E3 ubiquitin protein ligase 1 1.79771
PRMT3 protein arginine methyltransferase 3 1.79357
GPI glucose-6-phosphate isomerase 1.78754
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.78474
ACLY ATP citrate lyase 1.77862
CAPRIN2 caprin family member 2 1.7561
C9ORF3 chromosome 9 open reading frame 3 1.75176
WAC WW domain containing adaptor with coiled-coil 1.74442
TMEM37 transmembrane protein 37 1.73614
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.73476
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.7227
CYFIP1 cytoplasmic FMR1 interacting protein 1 1.71634
ASF1A anti-silencing function 1A histone chaperone 1.71622
AHCY adenosylhomocysteinase 1.70752
ZNF35 zinc finger protein 35 1.69134
TXNDC9 thioredoxin domain containing 9 1.67639
FRYL FRY-like 1.67519
PLAA phospholipase A2-activating protein 1.67129
SIN3A SIN3 transcription regulator family member A 1.67069
PELO pelota homolog (Drosophila) 1.66036
SYF2 SYF2 pre-mRNA-splicing factor 1.65005
LYRM2 LYR motif containing 2 1.6461
CLDN4 claudin 4 1.6392
RPS29 ribosomal protein S29 1.63536
ZC3HC1 zinc finger, C3HC-type containing 1 1.63037
FBXL5 F-box and leucine-rich repeat protein 5 1.62951
POU2F3 POU class 2 homeobox 3 1.62359
RPL10A ribosomal protein L10a 1.62357
FXN frataxin 1.6235
KCMF1 potassium channel modulatory factor 1 1.62147
GRK5 G protein-coupled receptor kinase 5 1.61879
CSHL1 chorionic somatomammotropin hormone-like 1 1.61476
PGRMC2 progesterone receptor membrane component 2 1.60849
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.6031
EIF3K eukaryotic translation initiation factor 3, subunit K 1.59349
RPL10 ribosomal protein L10 1.58821
AK4 adenylate kinase 4 1.57551
RPL13A ribosomal protein L13a 1.57181
PFKP phosphofructokinase, platelet 1.57018
NT5DC3 5'-nucleotidase domain containing 3 1.56715
KDM3B lysine (K)-specific demethylase 3B 1.55739
RPP30 ribonuclease P/MRP 30kDa subunit 1.55063
DPY30 dpy-30 homolog (C. elegans) 1.54682
KCNK7 potassium channel, two pore domain subfamily K, member 7 1.54326
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.54223
CDC26 cell division cycle 26 1.54047
SELK selenoprotein K 1.53708
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.52711
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.52471
GTF2B general transcription factor IIB 1.51687
OSBPL11 oxysterol binding protein-like 11 1.51583
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.51349
HDGF hepatoma-derived growth factor 1.50924
FAM83H family with sequence similarity 83, member H 1.50823
DCAF11 DDB1 and CUL4 associated factor 11 1.50795
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.50471
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.49967
GOLGA5 golgin A5 1.49834
LRP10 low density lipoprotein receptor-related protein 10 1.49112
LUC7L3 LUC7-like 3 (S. cerevisiae) 1.48902
BAZ2A bromodomain adjacent to zinc finger domain, 2A 1.48886
EXOC4 exocyst complex component 4 1.48786
NADK NAD kinase 1.48478
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1.48404
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 1.48039
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.47788
TARDBP TAR DNA binding protein 1.4768
NFS1 NFS1 cysteine desulfurase 1.46411
ACTG1 actin gamma 1 1.45719
C7ORF55 chromosome 7 open reading frame 55 1.45515
CWC22 CWC22 spliceosome-associated protein 1.44911
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 1.4481
C6ORF89 chromosome 6 open reading frame 89 1.44414
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.43309
GATA1 GATA binding protein 1 (globin transcription factor 1) 1.43265
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.43116
THOC7 THO complex 7 1.42841
RBBP6 retinoblastoma binding protein 6 1.42102
MIPOL1 mirror-image polydactyly 1 1.41794
COMMD7 COMM domain containing 7 1.40965
STARD7 StAR-related lipid transfer (START) domain containing 7 1.40887
PDS5B PDS5 cohesin associated factor B 1.408
DNM2 dynamin 2 1.39814
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.39492
PDCL3 phosducin-like 3 1.39407
PPL periplakin 1.39067
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.38599
RAP2B RAP2B, member of RAS oncogene family 1.38536
DCTN3 dynactin 3 (p22) 1.38523
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 1.37919
COL9A2 collagen, type IX, alpha 2 1.37742
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.37311
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.36924
WSB1 WD repeat and SOCS box containing 1 1.36751
NXF1 nuclear RNA export factor 1 1.35969
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.3579
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 1.35209
PQLC3 PQ loop repeat containing 3 1.35141
UBXN6 UBX domain protein 6 1.34959
CISD1 CDGSH iron sulfur domain 1 1.34629
C18ORF8 chromosome 18 open reading frame 8 1.34406
PHGDH phosphoglycerate dehydrogenase 1.3383
ACOT9 acyl-CoA thioesterase 9 1.33717
PTPRE protein tyrosine phosphatase, receptor type, E 1.33216
USO1 USO1 vesicle transport factor 1.32271
SENP6 SUMO1/sentrin specific peptidase 6 1.31527
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.31101
RBMS1 RNA binding motif, single stranded interacting protein 1 1.30889
ITGAV integrin, alpha V 1.30393
HCCS holocytochrome c synthase 1.30307
F11R F11 receptor 1.30222
ATXN2 ataxin 2 1.30102
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.29862
KLHL7 kelch-like family member 7 1.29583
CD99L2 CD99 molecule-like 2 1.28974
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.28845
S100A10 S100 calcium binding protein A10 1.28691
ANAPC16 anaphase promoting complex subunit 16 1.27555
C9ORF64 chromosome 9 open reading frame 64 1.27105
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.26486
FXR1 fragile X mental retardation, autosomal homolog 1 1.26351
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 1.26204
RAB14 RAB14, member RAS oncogene family 1.26098
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.25922
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.25372
REEP5 receptor accessory protein 5 1.25104
GATA5 GATA binding protein 5 1.24914
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.24802
LAMA1 laminin, alpha 1 1.24759
WDR43 WD repeat domain 43 1.24548
CXCL12 chemokine (C-X-C motif) ligand 12 1.24423
FANCG Fanconi anemia, complementation group G 1.24403
MRPL39 mitochondrial ribosomal protein L39 1.24213
FAF1 Fas (TNFRSF6) associated factor 1 1.23928
RBM8A RNA binding motif protein 8A 1.23669
SPRED2 sprouty-related, EVH1 domain containing 2 1.23563
STRBP spermatid perinuclear RNA binding protein 1.22962
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 1.22794
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.22764
STXBP1 syntaxin binding protein 1 1.225
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 1.21824
CUL2 cullin 2 1.21485
HPCAL4 hippocalcin like 4 1.21332
TFPI2 tissue factor pathway inhibitor 2 1.21267
SUMO3 small ubiquitin-like modifier 3 1.21076
MAX MYC associated factor X 1.21002
SS18 synovial sarcoma translocation, chromosome 18 1.20927
IL10 interleukin 10 1.20924
CCDC117 coiled-coil domain containing 117 1.20902
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.20612
CASP8AP2 caspase 8 associated protein 2 1.20204
SORBS1 sorbin and SH3 domain containing 1 1.19815
FLOT1 flotillin 1 1.19589
ZSCAN12 zinc finger and SCAN domain containing 12 1.19534
IRF9 interferon regulatory factor 9 1.1936
USP34 ubiquitin specific peptidase 34 1.19337
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.18761
SNAPIN SNAP-associated protein 1.18689
C12ORF45 chromosome 12 open reading frame 45 1.18688
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 1.18618
NPHP1 nephronophthisis 1 (juvenile) 1.1836
MRPL17 mitochondrial ribosomal protein L17 1.18168
WBP5 WW domain binding protein 5 1.18104
LOX lysyl oxidase 1.17656
SNX6 sorting nexin 6 1.17456
ZNRF4 zinc and ring finger 4 1.16823
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 1.16718
GUK1 guanylate kinase 1 1.16428
CDAN1 codanin 1 1.16403
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.16341
CRTAP cartilage associated protein 1.16284
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.15944
MFN1 mitofusin 1 1.15832
ZFR2 zinc finger RNA binding protein 2 1.15644
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 1.15071
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 1.1504
SNX3 sorting nexin 3 1.14808
GCLC glutamate-cysteine ligase, catalytic subunit 1.1471
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 1.14657
BLM Bloom syndrome, RecQ helicase-like 1.14619
CSF1R colony stimulating factor 1 receptor 1.14601
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 1.1449
PDE4DIP phosphodiesterase 4D interacting protein 1.14347
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.13704
ECH1 enoyl CoA hydratase 1, peroxisomal 1.137
RDX radixin 1.13532
KRT31 keratin 31, type I 1.13465
CBFB core-binding factor, beta subunit 1.13328
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.13166
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.12716
ZNF274 zinc finger protein 274 1.12573
CANT1 calcium activated nucleotidase 1 1.12379
COMMD1 copper metabolism (Murr1) domain containing 1 1.12059
ERO1LB ERO1-like beta (S. cerevisiae) 1.12039
GYG1 glycogenin 1 1.11757
BAG2 BCL2-associated athanogene 2 1.11665
INPP1 inositol polyphosphate-1-phosphatase 1.11184
IKZF4 IKAROS family zinc finger 4 (Eos) 1.1112
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.11117
LDAH lipid droplet associated hydrolase 1.11009
FAM162A family with sequence similarity 162, member A 1.10963
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.10931
RPN1 ribophorin I 1.10928
NDEL1 nudE neurodevelopment protein 1-like 1 1.10808
PRUNE prune exopolyphosphatase 1.10443
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 1.10426
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 1.09883
CLGN calmegin 1.09659
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 1.09603
POLR1C polymerase (RNA) I polypeptide C, 30kDa 1.09318
CLP1 cleavage and polyadenylation factor I subunit 1 1.09233
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 1.09107
CDADC1 cytidine and dCMP deaminase domain containing 1 1.09056
MTX2 metaxin 2 1.08792
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.08727
CLCNKB chloride channel, voltage-sensitive Kb 1.08649
CNOT4 CCR4-NOT transcription complex, subunit 4 1.08609
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 1.08503
POT1 protection of telomeres 1 1.08401
KRT6B keratin 6B, type II 1.08351
EXOSC8 exosome component 8 1.08267
COPS4 COP9 signalosome subunit 4 1.0802
ICA1 islet cell autoantigen 1, 69kDa 1.07936
GPX1 glutathione peroxidase 1 1.07742
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.07651
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.07635
FBL fibrillarin 1.07594
TEX15 testis expressed 15 1.07565

decreased expression

Symbol Name Standardized Value
TSTA3 tissue specific transplantation antigen P35B -4.62435
MAST3 microtubule associated serine/threonine kinase 3 -3.92799
RGS16 regulator of G-protein signaling 16 -3.28314
PADI2 peptidyl arginine deiminase, type II -3.09643
KIF3C kinesin family member 3C -3.05615
MNT MAX network transcriptional repressor -2.95193
F3 coagulation factor III (thromboplastin, tissue factor) -2.79731
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -2.72092
OLFM1 olfactomedin 1 -2.65367
PRKCA protein kinase C, alpha -2.64429
PBX1 pre-B-cell leukemia homeobox 1 -2.61862
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.59318
BHLHE40 basic helix-loop-helix family, member e40 -2.47929
KALRN kalirin, RhoGEF kinase -2.46612
PRKCB protein kinase C, beta -2.42222
ACVRL1 activin A receptor type II-like 1 -2.38543
TENM2 teneurin transmembrane protein 2 -2.30197
DGUOK deoxyguanosine kinase -2.26705
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) -2.26642
LMO2 LIM domain only 2 (rhombotin-like 1) -2.2136
ZBED3 zinc finger, BED-type containing 3 -2.20714
PID1 phosphotyrosine interaction domain containing 1 -2.20679
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.15677
PHLDB1 pleckstrin homology-like domain, family B, member 1 -2.09363
RCSD1 RCSD domain containing 1 -2.09223
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.0865
ADCY9 adenylate cyclase 9 -2.07444
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -2.06216
IPO4 importin 4 -2.04019
VEGFB vascular endothelial growth factor B -2.03686
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta -2.02716
FADS1 fatty acid desaturase 1 -2.02287
C20ORF24 chromosome 20 open reading frame 24 -2.01909
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.00072
ADCY2 adenylate cyclase 2 (brain) -1.95914
EPN1 epsin 1 -1.95577
SYN2 synapsin II -1.9277
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -1.92237
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -1.88219
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -1.88166
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -1.88094
SRM spermidine synthase -1.86163
PHB2 prohibitin 2 -1.86147
MERTK MER proto-oncogene, tyrosine kinase -1.8607
ZSWIM7 zinc finger, SWIM-type containing 7 -1.85145
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.84379
SEC23A Sec23 homolog A (S. cerevisiae) -1.83822
STX8 syntaxin 8 -1.83666
TSC22D1 TSC22 domain family, member 1 -1.8349
SUSD6 sushi domain containing 6 -1.82985
MAPK6 mitogen-activated protein kinase 6 -1.82591
ARHGAP39 Rho GTPase activating protein 39 -1.81254
FAM110A family with sequence similarity 110, member A -1.79204
TRIO trio Rho guanine nucleotide exchange factor -1.78921
PRKCD protein kinase C, delta -1.78594
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -1.77528
TSPAN7 tetraspanin 7 -1.75587
CS citrate synthase -1.75127
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit -1.74979
EIF6 eukaryotic translation initiation factor 6 -1.7409
GLG1 golgi glycoprotein 1 -1.72911
FJX1 four jointed box 1 (Drosophila) -1.72761
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.69265
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -1.69252
PTPRG protein tyrosine phosphatase, receptor type, G -1.69081
GTPBP4 GTP binding protein 4 -1.68759
RGS6 regulator of G-protein signaling 6 -1.67962
FKBP1A FK506 binding protein 1A, 12kDa -1.67376
PBX2 pre-B-cell leukemia homeobox 2 -1.65088
KIFC2 kinesin family member C2 -1.64753
ACYP1 acylphosphatase 1, erythrocyte (common) type -1.633
CHRAC1 chromatin accessibility complex 1 -1.62462
GPR12 G protein-coupled receptor 12 -1.61336
ADORA1 adenosine A1 receptor -1.60678
TMEM97 transmembrane protein 97 -1.59813
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -1.58696
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -1.58443
BAG1 BCL2-associated athanogene -1.57707
HOMER2 homer scaffolding protein 2 -1.56981
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.56879
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -1.56777
RGS14 regulator of G-protein signaling 14 -1.55106
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.55033
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.54534
WFS1 Wolfram syndrome 1 (wolframin) -1.54279
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.5385
NR4A1 nuclear receptor subfamily 4, group A, member 1 -1.51823
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) -1.51567
DCTN2 dynactin 2 (p50) -1.51522
AVP arginine vasopressin -1.51334
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -1.51254
REPIN1 replication initiator 1 -1.51185
GAB1 GRB2-associated binding protein 1 -1.50638
ADGRL2 adhesion G protein-coupled receptor L2 -1.4932
ATP13A3 ATPase type 13A3 -1.49127
OR13J1 olfactory receptor, family 13, subfamily J, member 1 -1.48168
MIEN1 migration and invasion enhancer 1 -1.47824
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -1.47476
CTGF connective tissue growth factor -1.46403
RECQL5 RecQ protein-like 5 -1.45862
ADGRL1 adhesion G protein-coupled receptor L1 -1.44766
AMH anti-Mullerian hormone -1.43672
RELL1 RELT-like 1 -1.43273
DUSP1 dual specificity phosphatase 1 -1.43081
ZFPM1 zinc finger protein, FOG family member 1 -1.42851
ZNF706 zinc finger protein 706 -1.40905
NRD1 nardilysin (N-arginine dibasic convertase) -1.4006
PNKP polynucleotide kinase 3'-phosphatase -1.39013
QDPR quinoid dihydropteridine reductase -1.37199
EGR2 early growth response 2 -1.36616
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -1.36389
PGAM2 phosphoglycerate mutase 2 (muscle) -1.36102
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.35578
MYL4 myosin, light chain 4, alkali; atrial, embryonic -1.3486
MOBP myelin-associated oligodendrocyte basic protein -1.34177
SSTR2 somatostatin receptor 2 -1.33911
CMIP c-Maf inducing protein -1.33804
RGS8 regulator of G-protein signaling 8 -1.31122
DHCR7 7-dehydrocholesterol reductase -1.31098
IGF2R insulin-like growth factor 2 receptor -1.30964
KCNK4 potassium channel, two pore domain subfamily K, member 4 -1.30911
CD63 CD63 molecule -1.30841
PGAM1 phosphoglycerate mutase 1 (brain) -1.30582
SGK1 serum/glucocorticoid regulated kinase 1 -1.30576
FBXW2 F-box and WD repeat domain containing 2 -1.30459
RASD1 RAS, dexamethasone-induced 1 -1.29273
PKN2 protein kinase N2 -1.29249
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -1.28889
CRCP CGRP receptor component -1.28831
ZBTB46 zinc finger and BTB domain containing 46 -1.28436
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -1.27889
HTRA1 HtrA serine peptidase 1 -1.27736
ADRA2C adrenoceptor alpha 2C -1.27426
RPS5 ribosomal protein S5 -1.27321
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.26117
GSTK1 glutathione S-transferase kappa 1 -1.25288
TBL2 transducin (beta)-like 2 -1.24137
ADGRD1 adhesion G protein-coupled receptor D1 -1.24007
HPCA hippocalcin -1.23957
EFNB3 ephrin-B3 -1.23889
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.23627
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -1.23571
HLA-DMA major histocompatibility complex, class II, DM alpha -1.23316
HPCAL1 hippocalcin-like 1 -1.22989
JAGN1 jagunal homolog 1 (Drosophila) -1.22867
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -1.22749
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -1.22321
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -1.22271
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.22023
TIMELESS timeless circadian clock -1.21668
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -1.2153
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -1.20827
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -1.20827
CDH13 cadherin 13 -1.20579
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -1.19394
MRPL16 mitochondrial ribosomal protein L16 -1.18666
NPY neuropeptide Y -1.18407
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.18152
DBP D site of albumin promoter (albumin D-box) binding protein -1.18068
FEN1 flap structure-specific endonuclease 1 -1.1741
CRYM crystallin, mu -1.17171
ZDHHC3 zinc finger, DHHC-type containing 3 -1.17142
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.1705
SEZ6L seizure related 6 homolog (mouse)-like -1.16767
EBP emopamil binding protein (sterol isomerase) -1.16605
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.16222
HS1BP3 HCLS1 binding protein 3 -1.15319
CD68 CD68 molecule -1.14641
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -1.14513
NHP2 NHP2 ribonucleoprotein -1.14419
TBC1D21 TBC1 domain family, member 21 -1.14169
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 -1.13726
ALDOC aldolase C, fructose-bisphosphate -1.13299
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.13065
ZDHHC14 zinc finger, DHHC-type containing 14 -1.1296
PLXNA2 plexin A2 -1.12908
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 -1.12443
GHITM growth hormone inducible transmembrane protein -1.12027
CCK cholecystokinin -1.11271
MEF2B myocyte enhancer factor 2B -1.10275
PARM1 prostate androgen-regulated mucin-like protein 1 -1.09687
KCTD17 potassium channel tetramerization domain containing 17 -1.09364
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.09228
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -1.08775
SEC16A SEC16 homolog A (S. cerevisiae) -1.08305
GNMT glycine N-methyltransferase -1.08169
PPIF peptidylprolyl isomerase F -1.08006
DDIT3 DNA-damage-inducible transcript 3 -1.07776
NDRG2 NDRG family member 2 -1.07627
RPL6 ribosomal protein L6 -1.07423
NPTX2 neuronal pentraxin II -1.07369
NAP1L1 nucleosome assembly protein 1-like 1 -1.07359
CYC1 cytochrome c-1 -1.0681
EFTUD2 elongation factor Tu GTP binding domain containing 2 -1.0648
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -1.06262
USP2 ubiquitin specific peptidase 2 -1.06095
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -1.06077
RPS7 ribosomal protein S7 -1.05869
NRIP1 nuclear receptor interacting protein 1 -1.0534
ARHGAP1 Rho GTPase activating protein 1 -1.0511
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.05021
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -1.04842
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -1.04619
SCARB2 scavenger receptor class B, member 2 -1.04273
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.04222
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -1.04215
AQP4 aquaporin 4 -1.04112
LDLR low density lipoprotein receptor -1.04006
SPAG7 sperm associated antigen 7 -1.03466
UFD1L ubiquitin fusion degradation 1 like (yeast) -1.03377
ANKRD33B ankyrin repeat domain 33B -1.03251
AMZ2 archaelysin family metallopeptidase 2 -1.02861
TRAPPC5 trafficking protein particle complex 5 -1.02854
TTC7B tetratricopeptide repeat domain 7B -1.0263
RBP4 retinol binding protein 4, plasma -1.02176
KLF9 Kruppel-like factor 9 -1.02133
NFYB nuclear transcription factor Y, beta -1.01938
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -1.01915
ALCAM activated leukocyte cell adhesion molecule -1.01118
GRIK2 glutamate receptor, ionotropic, kainate 2 -1.0096
PER1 period circadian clock 1 -1.00766
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.00707
WNT4 wingless-type MMTV integration site family, member 4 -1.00116
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -0.992856
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -0.98887
RXRG retinoid X receptor, gamma -0.986923
TMEM169 transmembrane protein 169 -0.985254
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.984966
IER2 immediate early response 2 -0.983984
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.980958
FOXO3 forkhead box O3 -0.978824
PLD2 phospholipase D2 -0.977691
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.967934
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -0.966945
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.966869
VIP vasoactive intestinal peptide -0.964845
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.964018
ZNF703 zinc finger protein 703 -0.961057
MAPK14 mitogen-activated protein kinase 14 -0.96093
JARID2 jumonji, AT rich interactive domain 2 -0.958596
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -0.95678
TMEM205 transmembrane protein 205 -0.954579
KCNK2 potassium channel, two pore domain subfamily K, member 2 -0.952971
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -0.952316
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -0.951717
P4HB prolyl 4-hydroxylase, beta polypeptide -0.951306
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -0.944328
OXT oxytocin/neurophysin I prepropeptide -0.943616
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -0.94016
PEX14 peroxisomal biogenesis factor 14 -0.93976
EMD emerin -0.939475
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.937816
KRT12 keratin 12, type I -0.936847
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -0.936114
THY1 Thy-1 cell surface antigen -0.934231
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.93269
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -0.932253
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -0.930323
JKAMP JNK1/MAPK8-associated membrane protein -0.92951
BTF3L4 basic transcription factor 3-like 4 -0.92647
UBL4A ubiquitin-like 4A -0.925841
MCAM melanoma cell adhesion molecule -0.925827
CBX6 chromobox homolog 6 -0.925479
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.925471
INHBA inhibin, beta A -0.924671
COCH cochlin -0.924304
FGF11 fibroblast growth factor 11 -0.922364
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -0.915802
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 -0.910291
ATG13 autophagy related 13 -0.906037
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -0.905797
SAC3D1 SAC3 domain containing 1 -0.901098
OVGP1 oviductal glycoprotein 1, 120kDa -0.898623
ENO2 enolase 2 (gamma, neuronal) -0.898413
NGEF neuronal guanine nucleotide exchange factor -0.898379
C9ORF114 chromosome 9 open reading frame 114 -0.89825
RAB34 RAB34, member RAS oncogene family -0.89555
SCP2 sterol carrier protein 2 -0.895069
SERTAD1 SERTA domain containing 1 -0.8949
INTS7 integrator complex subunit 7 -0.888046
GLO1 glyoxalase I -0.886248
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.880854
CAMK4 calcium/calmodulin-dependent protein kinase IV -0.88003
QKI QKI, KH domain containing, RNA binding -0.878093
UGCG UDP-glucose ceramide glucosyltransferase -0.876651
KIAA0100 KIAA0100 -0.875294
PRDX6 peroxiredoxin 6 -0.869065
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.868065
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -0.859206
ITGB7 integrin, beta 7 -0.855559
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -0.85177
IPO11 importin 11 -0.847887
FTH1 ferritin, heavy polypeptide 1 -0.847707
SRPK1 SRSF protein kinase 1 -0.846914
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.846665
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.846392
PRSS1 protease, serine, 1 (trypsin 1) -0.845206
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 -0.842839
PSAPL1 prosaposin-like 1 (gene/pseudogene) -0.841858
ADRB1 adrenoceptor beta 1 -0.840039
Funding