Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3583
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Genes

600 genes differentially expressed during Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 5.34167
CXCL2 chemokine (C-X-C motif) ligand 2 3.74177
PPIE peptidylprolyl isomerase E (cyclophilin E) 3.42751
GJA1 gap junction protein, alpha 1, 43kDa 3.39251
RPL13 ribosomal protein L13 3.38884
RPS10 ribosomal protein S10 3.35048
C20ORF194 chromosome 20 open reading frame 194 3.28558
RPL8 ribosomal protein L8 3.28264
ADORA2B adenosine A2b receptor 3.24155
PARK7 parkinson protein 7 3.07723
SOX5 SRY (sex determining region Y)-box 5 3.07507
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 3.03249
AARSD1 alanyl-tRNA synthetase domain containing 1 2.94165
VAMP8 vesicle-associated membrane protein 8 2.94043
TMCO4 transmembrane and coiled-coil domains 4 2.87431
LPAR2 lysophosphatidic acid receptor 2 2.86461
DDR2 discoidin domain receptor tyrosine kinase 2 2.83159
SCX scleraxis basic helix-loop-helix transcription factor 2.7676
THBS2 thrombospondin 2 2.70555
PRR12 proline rich 12 2.70465
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.67966
COL6A2 collagen, type VI, alpha 2 2.55475
EIF3I eukaryotic translation initiation factor 3, subunit I 2.40141
CTSZ cathepsin Z 2.3799
TNS1 tensin 1 2.3406
CDC26 cell division cycle 26 2.33936
NME1 NME/NM23 nucleoside diphosphate kinase 1 2.32618
TBRG1 transforming growth factor beta regulator 1 2.32508
C7ORF57 chromosome 7 open reading frame 57 2.31213
CTGF connective tissue growth factor 2.2874
COL3A1 collagen, type III, alpha 1 2.26809
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.2442
SOCS3 suppressor of cytokine signaling 3 2.21861
FKBP5 FK506 binding protein 5 2.21222
FAM45A family with sequence similarity 45, member A 2.1701
TMEM176B transmembrane protein 176B 2.14236
IL1RN interleukin 1 receptor antagonist 2.10646
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.07634
ACO1 aconitase 1, soluble 2.07579
RPL13A ribosomal protein L13a 2.07412
GRSF1 G-rich RNA sequence binding factor 1 2.05665
KLHL13 kelch-like family member 13 2.04849
METAP1D methionyl aminopeptidase type 1D (mitochondrial) 2.03893
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.00679
COPS4 COP9 signalosome subunit 4 2.00297
NOV nephroblastoma overexpressed 1.99048
HOPX HOP homeobox 1.98514
IGFBP7 insulin-like growth factor binding protein 7 1.97867
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 1.97416
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.95664
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.95276
CRLF1 cytokine receptor-like factor 1 1.94079
COL5A2 collagen, type V, alpha 2 1.93729
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.91899
ADHFE1 alcohol dehydrogenase, iron containing, 1 1.8812
RNF114 ring finger protein 114 1.85788
STAU1 staufen double-stranded RNA binding protein 1 1.84745
PRDX1 peroxiredoxin 1 1.8393
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.83895
PLAGL1 pleiomorphic adenoma gene-like 1 1.82884
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 1.8219
RPS6 ribosomal protein S6 1.78408
BAG3 BCL2-associated athanogene 3 1.78211
TMEM242 transmembrane protein 242 1.77572
SERF2 small EDRK-rich factor 2 1.73619
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.71911
ANAPC7 anaphase promoting complex subunit 7 1.71316
RPL7A ribosomal protein L7a 1.70325
RGMB repulsive guidance molecule family member b 1.70129
COL1A1 collagen, type I, alpha 1 1.69704
NINJ1 ninjurin 1 1.68758
FAM13C family with sequence similarity 13, member C 1.68187
HTRA1 HtrA serine peptidase 1 1.67578
FOXO3 forkhead box O3 1.67192
BGN biglycan 1.66725
HIST1H1C histone cluster 1, H1c 1.65986
PLCD1 phospholipase C, delta 1 1.61252
PEAR1 platelet endothelial aggregation receptor 1 1.60784
ZNF469 zinc finger protein 469 1.607
IGFBP6 insulin-like growth factor binding protein 6 1.60208
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.5832
GIGYF2 GRB10 interacting GYF protein 2 1.57331
FBLN2 fibulin 2 1.558
PSD3 pleckstrin and Sec7 domain containing 3 1.55034
TPPP3 tubulin polymerization-promoting protein family member 3 1.54995
RFTN2 raftlin family member 2 1.54759
FAM132A family with sequence similarity 132, member A 1.54367
TMEM214 transmembrane protein 214 1.53462
SIM2 single-minded family bHLH transcription factor 2 1.53081
RPS2 ribosomal protein S2 1.52916
PFDN1 prefoldin subunit 1 1.52211
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 1.52044
FBN1 fibrillin 1 1.50492
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.50305
BRD1 bromodomain containing 1 1.5007
TUBA4A tubulin, alpha 4a 1.49992
COL1A2 collagen, type I, alpha 2 1.49625
PEG3 paternally expressed 3 1.49279
GAS1 growth arrest-specific 1 1.47487
SQRDL sulfide quinone reductase-like (yeast) 1.46875
C9ORF156 chromosome 9 open reading frame 156 1.46858
TCF25 transcription factor 25 (basic helix-loop-helix) 1.46336
COL6A1 collagen, type VI, alpha 1 1.46122
TGFBI transforming growth factor, beta-induced, 68kDa 1.46008
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.45835
MECOM MDS1 and EVI1 complex locus 1.45816
SCRIB scribbled planar cell polarity protein 1.44618
APRT adenine phosphoribosyltransferase 1.44378
H2AFZ H2A histone family, member Z 1.4354
OSMR oncostatin M receptor 1.43182
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.42601
FGD4 FYVE, RhoGEF and PH domain containing 4 1.42501
BCOR BCL6 corepressor 1.42253
FAM114A1 family with sequence similarity 114, member A1 1.41603
LY6E lymphocyte antigen 6 complex, locus E 1.40264
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.3936
FAM101B family with sequence similarity 101, member B 1.39248
CTC1 CTS telomere maintenance complex component 1 1.38983
RPS19 ribosomal protein S19 1.35881
KANSL1L KAT8 regulatory NSL complex subunit 1-like 1.35865
KEL Kell blood group, metallo-endopeptidase 1.35268
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 1.34936
WASH1 WAS protein family homolog 1 1.33804
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.32504
DIEXF digestive organ expansion factor homolog (zebrafish) 1.32283
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like 1.32041
NEURL1 neuralized E3 ubiquitin protein ligase 1 1.31856
HORMAD1 HORMA domain containing 1 1.31667
RPL5 ribosomal protein L5 1.31249
PRKCA protein kinase C, alpha 1.31235
FGF7 fibroblast growth factor 7 1.30969
PDLIM1 PDZ and LIM domain 1 1.30837
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 1.30166
C5ORF42 chromosome 5 open reading frame 42 1.29991
WLS wntless Wnt ligand secretion mediator 1.29856
CST3 cystatin C 1.29628
RPL6 ribosomal protein L6 1.28782
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.28511
DLK1 delta-like 1 homolog (Drosophila) 1.2807
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.27715
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.27434
NOP10 NOP10 ribonucleoprotein 1.2731
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 1.26867
TRAF1 TNF receptor-associated factor 1 1.26688
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.26526
AKT1S1 AKT1 substrate 1 (proline-rich) 1.26401
MPP1 membrane protein, palmitoylated 1, 55kDa 1.26344
ANTXR1 anthrax toxin receptor 1 1.24437
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1.24259
MGST2 microsomal glutathione S-transferase 2 1.24125
SOX4 SRY (sex determining region Y)-box 4 1.23819
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.2271
GTF2A2 general transcription factor IIA, 2, 12kDa 1.22356
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 1.2123
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 1.21028
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.20832
RPS27L ribosomal protein S27-like 1.19867
AKAP8L A kinase (PRKA) anchor protein 8-like 1.19233
MGP matrix Gla protein 1.1917
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.1911
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.18914
ANKRD12 ankyrin repeat domain 12 1.18549
DCN decorin 1.18438
CCL13 chemokine (C-C motif) ligand 13 1.18044
CCL5 chemokine (C-C motif) ligand 5 1.17835
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.17494
HSPG2 heparan sulfate proteoglycan 2 1.17413
SCP2 sterol carrier protein 2 1.16985
RPL18 ribosomal protein L18 1.1666
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.16636
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 1.16553
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.16358
TSACC TSSK6 activating co-chaperone 1.15467
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.15209
TRAM1 translocation associated membrane protein 1 1.13464
UBFD1 ubiquitin family domain containing 1 1.13296
S100A16 S100 calcium binding protein A16 1.13033
LDLRAP1 low density lipoprotein receptor adaptor protein 1 1.1254
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.12312
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.12199
GPN3 GPN-loop GTPase 3 1.12095
TMED2 transmembrane emp24 domain trafficking protein 2 1.1176
GSTO1 glutathione S-transferase omega 1 1.1174
UNC13C unc-13 homolog C (C. elegans) 1.11521
FLRT3 fibronectin leucine rich transmembrane protein 3 1.10822
RPS28 ribosomal protein S28 1.1069
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.10484
SH3BP1 SH3-domain binding protein 1 1.10172
GTF3A general transcription factor IIIA 1.09956
S100A6 S100 calcium binding protein A6 1.09874
HINT2 histidine triad nucleotide binding protein 2 1.08834
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.08777
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.07436
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.07019
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.07018
CLCC1 chloride channel CLIC-like 1 1.06594
IGFBP4 insulin-like growth factor binding protein 4 1.06298
HOXA11 homeobox A11 1.05891
CAV1 caveolin 1, caveolae protein, 22kDa 1.05451
LRP5 low density lipoprotein receptor-related protein 5 1.05402
DNM2 dynamin 2 1.0537
TMEM37 transmembrane protein 37 1.05239
CTH cystathionine gamma-lyase 1.0441
RECQL RecQ helicase-like 1.04343
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 1.03791
MRPS31 mitochondrial ribosomal protein S31 1.03301
RPL4 ribosomal protein L4 1.03157
LY75 lymphocyte antigen 75 1.0271
NAGK N-acetylglucosamine kinase 1.02668
FBLN5 fibulin 5 1.02616
IGFBP5 insulin-like growth factor binding protein 5 1.02535
EIF3L eukaryotic translation initiation factor 3, subunit L 1.02523
TBC1D16 TBC1 domain family, member 16 1.02181
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.02176
LHFPL2 lipoma HMGIC fusion partner-like 2 1.01373
PGM3 phosphoglucomutase 3 1.00809
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.00619
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 1.00579
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.00401
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 1.00263
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.999485
DNPEP aspartyl aminopeptidase 0.998818
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.995608
WDFY3 WD repeat and FYVE domain containing 3 0.992254
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 0.992102
STBD1 starch binding domain 1 0.990593
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.989928
RPLP0 ribosomal protein, large, P0 0.986328
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.985994
ATOX1 antioxidant 1 copper chaperone 0.983217
MYH10 myosin, heavy chain 10, non-muscle 0.981923
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.981177
TRAPPC2L trafficking protein particle complex 2-like 0.978176
GP2 glycoprotein 2 (zymogen granule membrane) 0.977789
HNF1B HNF1 homeobox B 0.976917
PTX3 pentraxin 3, long 0.971234
FIG4 FIG4 phosphoinositide 5-phosphatase 0.970289
RPL11 ribosomal protein L11 0.966646
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.965059
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.964523
POU2F1 POU class 2 homeobox 1 0.962758
GLO1 glyoxalase I 0.961584
MATN2 matrilin 2 0.959089
AEBP1 AE binding protein 1 0.95866
FN1 fibronectin 1 0.954698
DENR density-regulated protein 0.953658
LOXL1 lysyl oxidase-like 1 0.953044
FKBP7 FK506 binding protein 7 0.950804
HOXC5 homeobox C5 0.95079
RNASE4 ribonuclease, RNase A family, 4 0.950431
AMDHD2 amidohydrolase domain containing 2 0.948812
GADD45A growth arrest and DNA-damage-inducible, alpha 0.946562
KITLG KIT ligand 0.944154
FAM3C family with sequence similarity 3, member C 0.943898
MMP2 matrix metallopeptidase 2 0.942755
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.941024
PAX9 paired box 9 0.94006
FHL2 four and a half LIM domains 2 0.939906
FNDC3A fibronectin type III domain containing 3A 0.935975
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.933635
TMED3 transmembrane emp24 protein transport domain containing 3 0.931169
ANXA13 annexin A13 0.929861
RSPO2 R-spondin 2 0.929237
MFAP5 microfibrillar associated protein 5 0.928587
PAX8 paired box 8 0.922727
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.922058
DDB2 damage-specific DNA binding protein 2, 48kDa 0.919192
ZCCHC5 zinc finger, CCHC domain containing 5 0.918329
ZNF622 zinc finger protein 622 0.917652
H2AFX H2A histone family, member X 0.914289
MPG N-methylpurine-DNA glycosylase 0.909047
MAGED2 melanoma antigen family D2 0.908546
MAU2 MAU2 sister chromatid cohesion factor 0.908544
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.908278
CCDC53 coiled-coil domain containing 53 0.905156
SH3PXD2A SH3 and PX domains 2A 0.904547
ZNF318 zinc finger protein 318 0.900787
STAP2 signal transducing adaptor family member 2 0.899643
TPD52L2 tumor protein D52-like 2 0.898631
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.897938
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.897362
SPIRE2 spire-type actin nucleation factor 2 0.896889
PDGFRL platelet-derived growth factor receptor-like 0.892024
COL9A3 collagen, type IX, alpha 3 0.890745
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.890361
DAP death-associated protein 0.889404
CREB3 cAMP responsive element binding protein 3 0.886519
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.883871
ADM adrenomedullin 0.883141
RPL37A ribosomal protein L37a 0.882558
RPL3 ribosomal protein L3 0.88238
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.881777
SNX1 sorting nexin 1 0.881303
F11R F11 receptor 0.880863
PLEKHN1 pleckstrin homology domain containing, family N member 1 0.880723
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.879062
TSC22D4 TSC22 domain family, member 4 0.8766
GMDS GDP-mannose 4,6-dehydratase 0.876217
UBL5 ubiquitin-like 5 0.873251
PLA2G16 phospholipase A2, group XVI 0.872297

decreased expression

Symbol Name Standardized Value
ADAMTSL3 ADAMTS-like 3 -4.72639
RORB RAR-related orphan receptor B -4.27204
TNNT2 troponin T type 2 (cardiac) -3.96452
IL1RAP interleukin 1 receptor accessory protein -3.73146
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -3.35257
LGALS1 lectin, galactoside-binding, soluble, 1 -3.27136
SOX11 SRY (sex determining region Y)-box 11 -3.22584
PLXNA2 plexin A2 -3.03974
PHB2 prohibitin 2 -3.01398
KIAA1217 KIAA1217 -3.0056
OPHN1 oligophrenin 1 -2.99749
HLA-A major histocompatibility complex, class I, A -2.81008
PGAM1 phosphoglycerate mutase 1 (brain) -2.80133
NOP2 NOP2 nucleolar protein -2.73
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.72014
ECE1 endothelin converting enzyme 1 -2.66808
PHGDH phosphoglycerate dehydrogenase -2.62841
RIMS2 regulating synaptic membrane exocytosis 2 -2.61397
TCP1 t-complex 1 -2.52881
OSBPL1A oxysterol binding protein-like 1A -2.43532
MARK4 MAP/microtubule affinity-regulating kinase 4 -2.42685
SVIL supervillin -2.39041
PRUNE2 prune homolog 2 (Drosophila) -2.38851
MVK mevalonate kinase -2.38024
AIF1L allograft inflammatory factor 1-like -2.35871
MGST1 microsomal glutathione S-transferase 1 -2.32477
ZNRF3 zinc and ring finger 3 -2.27813
ARHGAP6 Rho GTPase activating protein 6 -2.26635
F2RL1 coagulation factor II (thrombin) receptor-like 1 -2.26465
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -2.2467
PLTP phospholipid transfer protein -2.23703
ZNF697 zinc finger protein 697 -2.23681
PDZRN3 PDZ domain containing ring finger 3 -2.18455
IL4R interleukin 4 receptor -2.16793
SCN7A sodium channel, voltage gated, type VII alpha subunit -2.15466
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -2.14147
CFL1 cofilin 1 (non-muscle) -2.05944
EXT1 exostosin glycosyltransferase 1 -2.04887
NOTCH2 notch 2 -1.99744
ZDHHC6 zinc finger, DHHC-type containing 6 -1.98674
ZUFSP zinc finger with UFM1-specific peptidase domain -1.95872
S100A4 S100 calcium binding protein A4 -1.95303
PTGR1 prostaglandin reductase 1 -1.95246
MRPL55 mitochondrial ribosomal protein L55 -1.93912
C3ORF70 chromosome 3 open reading frame 70 -1.92286
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B -1.91861
LHX2 LIM homeobox 2 -1.91825
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.89629
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.89444
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -1.8924
LXN latexin -1.83605
G6PD glucose-6-phosphate dehydrogenase -1.83154
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 -1.8027
SORBS2 sorbin and SH3 domain containing 2 -1.79687
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -1.783
TENM3 teneurin transmembrane protein 3 -1.76686
FBXO16 F-box protein 16 -1.74616
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -1.72857
GAPDH glyceraldehyde-3-phosphate dehydrogenase -1.71513
TSPAN15 tetraspanin 15 -1.6966
ARHGAP24 Rho GTPase activating protein 24 -1.69065
FLNA filamin A, alpha -1.6906
DYSF dysferlin -1.6869
RPS14 ribosomal protein S14 -1.63748
BMPER BMP binding endothelial regulator -1.63501
POU3F4 POU class 3 homeobox 4 -1.63052
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -1.61071
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.60536
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -1.60475
HAS2 hyaluronan synthase 2 -1.58774
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -1.58277
COMTD1 catechol-O-methyltransferase domain containing 1 -1.5673
SCRN1 secernin 1 -1.56094
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -1.55933
VCAM1 vascular cell adhesion molecule 1 -1.55917
CLCN5 chloride channel, voltage-sensitive 5 -1.53145
TUBA1A tubulin, alpha 1a -1.52652
ANGPTL4 angiopoietin-like 4 -1.52399
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -1.52117
ELK1 ELK1, member of ETS oncogene family -1.50721
BTBD11 BTB (POZ) domain containing 11 -1.50458
TMEM171 transmembrane protein 171 -1.4932
CCDC151 coiled-coil domain containing 151 -1.46858
KIAA1524 KIAA1524 -1.44895
INTS9 integrator complex subunit 9 -1.44098
GSTM1 glutathione S-transferase mu 1 -1.43912
ZBTB7B zinc finger and BTB domain containing 7B -1.43437
SIPA1L1 signal-induced proliferation-associated 1 like 1 -1.41147
TRAP1 TNF receptor-associated protein 1 -1.41124
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -1.40987
DCAF5 DDB1 and CUL4 associated factor 5 -1.40983
E2F5 E2F transcription factor 5, p130-binding -1.40721
RAB7B RAB7B, member RAS oncogene family -1.4031
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.40276
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -1.39805
TUBB2B tubulin, beta 2B class IIb -1.39598
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -1.39585
C14ORF2 chromosome 14 open reading frame 2 -1.38973
C9ORF3 chromosome 9 open reading frame 3 -1.38721
ALDOA aldolase A, fructose-bisphosphate -1.37511
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -1.36113
LPCAT1 lysophosphatidylcholine acyltransferase 1 -1.35574
ACAA2 acetyl-CoA acyltransferase 2 -1.3555
MINK1 misshapen-like kinase 1 -1.35003
RPL26 ribosomal protein L26 -1.34154
COMMD9 COMM domain containing 9 -1.34108
FHL1 four and a half LIM domains 1 -1.33992
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -1.32457
FBXO7 F-box protein 7 -1.3243
KIF22 kinesin family member 22 -1.32357
HTT huntingtin -1.32132
SLC22A23 solute carrier family 22, member 23 -1.30979
GRAMD1B GRAM domain containing 1B -1.2986
HN1 hematological and neurological expressed 1 -1.2881
LYN LYN proto-oncogene, Src family tyrosine kinase -1.28524
FIGNL1 fidgetin-like 1 -1.28456
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.27571
CELF2 CUGBP, Elav-like family member 2 -1.27353
CDCA4 cell division cycle associated 4 -1.26609
COTL1 coactosin-like F-actin binding protein 1 -1.26445
CDC34 cell division cycle 34 -1.26356
C7ORF55 chromosome 7 open reading frame 55 -1.26226
CACYBP calcyclin binding protein -1.26134
ITGA7 integrin, alpha 7 -1.25869
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.25826
PRSS23 protease, serine, 23 -1.25618
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.24987
ATXN7L1 ataxin 7-like 1 -1.24922
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -1.24904
JAM3 junctional adhesion molecule 3 -1.24886
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.24796
TMCO6 transmembrane and coiled-coil domains 6 -1.24627
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -1.24627
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -1.24381
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.23906
RAP1GAP2 RAP1 GTPase activating protein 2 -1.23789
FDPS farnesyl diphosphate synthase -1.23092
PPARG peroxisome proliferator-activated receptor gamma -1.22934
EBP emopamil binding protein (sterol isomerase) -1.22452
NUF2 NUF2, NDC80 kinetochore complex component -1.22295
PGK1 phosphoglycerate kinase 1 -1.21493
PTN pleiotrophin -1.21477
ITM2B integral membrane protein 2B -1.21272
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -1.20906
FTL ferritin, light polypeptide -1.20089
TSC22D1 TSC22 domain family, member 1 -1.18503
SNRPF small nuclear ribonucleoprotein polypeptide F -1.18025
C21ORF59 chromosome 21 open reading frame 59 -1.17692
CR1L complement component (3b/4b) receptor 1-like -1.16743
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -1.16459
PTPRK protein tyrosine phosphatase, receptor type, K -1.16428
RANBP1 RAN binding protein 1 -1.16304
PKP2 plakophilin 2 -1.14712
COL7A1 collagen, type VII, alpha 1 -1.14312
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -1.13668
IDI1 isopentenyl-diphosphate delta isomerase 1 -1.13572
SNN stannin -1.1345
F2R coagulation factor II (thrombin) receptor -1.1343
MFGE8 milk fat globule-EGF factor 8 protein -1.12892
GPATCH2 G patch domain containing 2 -1.12116
SLC38A1 solute carrier family 38, member 1 -1.11931
CNST consortin, connexin sorting protein -1.11815
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.10699
SEPT9 septin 9 -1.1062
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -1.10232
MEIS2 Meis homeobox 2 -1.09221
CRYAB crystallin, alpha B -1.09113
GANC glucosidase, alpha; neutral C -1.0898
LTBP1 latent transforming growth factor beta binding protein 1 -1.08818
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.08749
CHERP calcium homeostasis endoplasmic reticulum protein -1.08742
CHML choroideremia-like (Rab escort protein 2) -1.08704
PNKP polynucleotide kinase 3'-phosphatase -1.08358
PARP9 poly (ADP-ribose) polymerase family, member 9 -1.08273
RBBP7 retinoblastoma binding protein 7 -1.08066
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -1.07953
TLR3 toll-like receptor 3 -1.07948
INHBB inhibin, beta B -1.07562
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.07537
TUFM Tu translation elongation factor, mitochondrial -1.0698
CD151 CD151 molecule (Raph blood group) -1.06918
SOX6 SRY (sex determining region Y)-box 6 -1.06704
DDR1 discoidin domain receptor tyrosine kinase 1 -1.06596
BOLA3 bolA family member 3 -1.0621
COCH cochlin -1.06195
PNP purine nucleoside phosphorylase -1.0619
SYTL2 synaptotagmin-like 2 -1.06023
ARMC1 armadillo repeat containing 1 -1.05968
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 -1.05673
DONSON downstream neighbor of SON -1.05527
AFTPH aftiphilin -1.05469
PRC1 protein regulator of cytokinesis 1 -1.05094
B3GNT1 -1.04952
FTH1 ferritin, heavy polypeptide 1 -1.04715
LHX1 LIM homeobox 1 -1.04706
KLF5 Kruppel-like factor 5 (intestinal) -1.04571
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.03743
KLHL25 kelch-like family member 25 -1.0331
VLDLR very low density lipoprotein receptor -1.03054
ACTG1 actin gamma 1 -1.02912
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -1.02668
EFTUD2 elongation factor Tu GTP binding domain containing 2 -1.02418
COL12A1 collagen, type XII, alpha 1 -1.02238
PLVAP plasmalemma vesicle associated protein -1.01938
DCBLD1 discoidin, CUB and LCCL domain containing 1 -1.01195
IL17RD interleukin 17 receptor D -1.01115
TEX261 testis expressed 261 -1.01076
PROK2 prokineticin 2 -1.01073
MRPL38 mitochondrial ribosomal protein L38 -1.01013
MDH1 malate dehydrogenase 1, NAD (soluble) -1.00986
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -1.00813
TPI1 triosephosphate isomerase 1 -1.00754
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 -1.00381
TEAD2 TEA domain family member 2 -1.00237
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -0.99517
AURKAIP1 aurora kinase A interacting protein 1 -0.981877
CTSD cathepsin D -0.980637
ANKRD44 ankyrin repeat domain 44 -0.979991
TALDO1 transaldolase 1 -0.978424
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.978391
CHMP4C charged multivesicular body protein 4C -0.973206
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -0.973101
PTCHD3 patched domain containing 3 -0.972446
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -0.972101
AVPI1 arginine vasopressin-induced 1 -0.971993
TPM3 tropomyosin 3 -0.969804
TSPAN7 tetraspanin 7 -0.968225
DGKH diacylglycerol kinase, eta -0.966696
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -0.963619
TWIST2 twist family bHLH transcription factor 2 -0.962893
STOM stomatin -0.954384
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -0.951236
EPDR1 ependymin related 1 -0.944328
KSR1 kinase suppressor of ras 1 -0.944262
CPXM2 carboxypeptidase X (M14 family), member 2 -0.942554
SLC38A7 solute carrier family 38, member 7 -0.941708
TSPYL2 TSPY-like 2 -0.940927
NT5C 5', 3'-nucleotidase, cytosolic -0.938445
SALL3 spalt-like transcription factor 3 -0.937704
ZNF329 zinc finger protein 329 -0.937427
DENND1A DENN/MADD domain containing 1A -0.933896
SF3B4 splicing factor 3b, subunit 4, 49kDa -0.933234
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -0.932473
IVD isovaleryl-CoA dehydrogenase -0.930297
LRP2 low density lipoprotein receptor-related protein 2 -0.930106
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -0.928303
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -0.924688
DDHD1 DDHD domain containing 1 -0.924436
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -0.921913
ZC3H14 zinc finger CCCH-type containing 14 -0.918414
MTUS2 microtubule associated tumor suppressor candidate 2 -0.915472
SYT11 synaptotagmin XI -0.915198
TIMP1 TIMP metallopeptidase inhibitor 1 -0.91138
HPS5 Hermansky-Pudlak syndrome 5 -0.908728
FBF1 Fas (TNFRSF6) binding factor 1 -0.906111
RPN1 ribophorin I -0.906032
FAM73A family with sequence similarity 73, member A -0.905722
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.903299
KRTDAP keratinocyte differentiation-associated protein -0.895632
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.893658
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -0.893505
ENO3 enolase 3 (beta, muscle) -0.885464
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.884465
WISP1 WNT1 inducible signaling pathway protein 1 -0.884166
EFNB2 ephrin-B2 -0.882357
SLC25A39 solute carrier family 25, member 39 -0.881426
PALLD palladin, cytoskeletal associated protein -0.880759
EHD3 EH-domain containing 3 -0.879178
AHR aryl hydrocarbon receptor -0.877134
TPST2 tyrosylprotein sulfotransferase 2 -0.877118
HPCAL1 hippocalcin-like 1 -0.876554
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.875608
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -0.872153
ATF7IP activating transcription factor 7 interacting protein -0.870625
LASP1 LIM and SH3 protein 1 -0.86974
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.869184
RAB27B RAB27B, member RAS oncogene family -0.867087
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.862586
LRRC58 leucine rich repeat containing 58 -0.855331
CLHC1 clathrin heavy chain linker domain containing 1 -0.848687
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -0.847375
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -0.84677
CCDC63 coiled-coil domain containing 63 -0.845299
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.844219
AQP5 aquaporin 5 -0.843253
LDHA lactate dehydrogenase A -0.842716
PDE4B phosphodiesterase 4B, cAMP-specific -0.842615
CDKL3 cyclin-dependent kinase-like 3 -0.84257
BDNF brain-derived neurotrophic factor -0.841912
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.841753
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.841223
ATG3 autophagy related 3 -0.838454
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.833994
SYNGR1 synaptogyrin 1 -0.832947
SDCBP syndecan binding protein (syntenin) -0.83253
RGS16 regulator of G-protein signaling 16 -0.831777
PBX1 pre-B-cell leukemia homeobox 1 -0.831658
NIN ninein (GSK3B interacting protein) -0.829532
RPL35A ribosomal protein L35a -0.829103
ATOH8 atonal homolog 8 (Drosophila) -0.828192