Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9375
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
LPIN2 lipin 2 5.01768
TMEM62 transmembrane protein 62 3.79152
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.74078
SARS2 seryl-tRNA synthetase 2, mitochondrial 3.73102
LIG1 ligase I, DNA, ATP-dependent 3.68521
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 3.66593
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 3.49868
NEK2 NIMA-related kinase 2 3.37892
SNX27 sorting nexin family member 27 3.28846
FAM63A family with sequence similarity 63, member A 3.17851
CXCL2 chemokine (C-X-C motif) ligand 2 3.13499
IRF2BP1 interferon regulatory factor 2 binding protein 1 3.03071
SLC38A5 solute carrier family 38, member 5 2.94975
PDCD6IP programmed cell death 6 interacting protein 2.92256
FXN frataxin 2.85592
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.84216
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.81725
SCG3 secretogranin III 2.76911
TNPO1 transportin 1 2.75071
SAR1B secretion associated, Ras related GTPase 1B 2.73705
MTTP microsomal triglyceride transfer protein 2.69364
IL2RG interleukin 2 receptor, gamma 2.6288
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.6271
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 2.60358
OTUD7B OTU deubiquitinase 7B 2.534
KLF17 Kruppel-like factor 17 2.52152
PRODH2 proline dehydrogenase (oxidase) 2 2.51202
FERMT3 fermitin family member 3 2.49088
KIF22 kinesin family member 22 2.47795
SLC22A18 solute carrier family 22, member 18 2.45116
TMPRSS2 transmembrane protease, serine 2 2.44954
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 2.44112
IHH indian hedgehog 2.42804
TM4SF5 transmembrane 4 L six family member 5 2.39763
IFI16 interferon, gamma-inducible protein 16 2.35712
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.33874
ARG2 arginase 2 2.3167
LY75 lymphocyte antigen 75 2.30199
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.29173
PARN poly(A)-specific ribonuclease 2.26585
TTC14 tetratricopeptide repeat domain 14 2.24975
SFT2D1 SFT2 domain containing 1 2.24003
LMOD2 leiomodin 2 (cardiac) 2.23728
PCTP phosphatidylcholine transfer protein 2.23656
ITGB5 integrin, beta 5 2.22432
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.19691
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 2.16743
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2.15498
UEVLD UEV and lactate/malate dehyrogenase domains 2.15367
CDC25C cell division cycle 25C 2.14462
CD36 CD36 molecule (thrombospondin receptor) 2.13194
MAOA monoamine oxidase A 2.10567
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.10389
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.09929
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.09264
NEO1 neogenin 1 2.08928
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.07579
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.03795
LGALS2 lectin, galactoside-binding, soluble, 2 2.03281
PRRX2 paired related homeobox 2 2.0175
LIFR leukemia inhibitory factor receptor alpha 2.01116
HMX1 H6 family homeobox 1 2.00653
BDKRB2 bradykinin receptor B2 1.99434
TARBP2 TAR (HIV-1) RNA binding protein 2 1.991
MYB v-myb avian myeloblastosis viral oncogene homolog 1.98623
GGPS1 geranylgeranyl diphosphate synthase 1 1.98299
NAT6 N-acetyltransferase 6 (GCN5-related) 1.9822
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.96201
IL18R1 interleukin 18 receptor 1 1.95151
DRD4 dopamine receptor D4 1.94593
USP1 ubiquitin specific peptidase 1 1.93877
HBG2 hemoglobin, gamma G 1.93414
ADGRE1 adhesion G protein-coupled receptor E1 1.90999
GATA6 GATA binding protein 6 1.89114
OCA2 oculocutaneous albinism II 1.88957
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.88454
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 1.87721
SLC44A4 solute carrier family 44, member 4 1.87437
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.87311
H19 H19, imprinted maternally expressed transcript (non-protein coding) 1.86554
AREG amphiregulin 1.81922
TBRG4 transforming growth factor beta regulator 4 1.81018
ZNF322 zinc finger protein 322 1.80508
ALAD aminolevulinate dehydratase 1.80056
SIX2 SIX homeobox 2 1.79824
TULP3 tubby like protein 3 1.78064
SEC11C SEC11 homolog C (S. cerevisiae) 1.7788
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.77585
KRTAP13-2 keratin associated protein 13-2 1.76344
C11ORF54 chromosome 11 open reading frame 54 1.76164
CENPE centromere protein E, 312kDa 1.76108
S100A5 S100 calcium binding protein A5 1.75935
PDCD7 programmed cell death 7 1.75281
ANGPT1 angiopoietin 1 1.74444
GATAD2A GATA zinc finger domain containing 2A 1.7417
RHOG ras homolog family member G 1.73846
STK24 serine/threonine kinase 24 1.7285
LIN7C lin-7 homolog C (C. elegans) 1.72446
STBD1 starch binding domain 1 1.72228
KLC4 kinesin light chain 4 1.71407
UTS2R urotensin 2 receptor 1.70893
GDF9 growth differentiation factor 9 1.70781
COL6A1 collagen, type VI, alpha 1 1.70071
PLIN1 perilipin 1 1.70049
UHMK1 U2AF homology motif (UHM) kinase 1 1.69141
BLNK B-cell linker 1.6881
PCDHA13 protocadherin alpha 13 1.68296
HAS3 hyaluronan synthase 3 1.68272
CAB39L calcium binding protein 39-like 1.68184
KLRC1 killer cell lectin-like receptor subfamily C, member 1 1.67604
PDLIM1 PDZ and LIM domain 1 1.67359
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1.67153
LRMP lymphoid-restricted membrane protein 1.67011
PLA2G1B phospholipase A2, group IB (pancreas) 1.66997
WSB1 WD repeat and SOCS box containing 1 1.66488
SVIL supervillin 1.66456
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.6635
NUP62 nucleoporin 62kDa 1.65963
DPEP1 dipeptidase 1 (renal) 1.65645
SELV selenoprotein V 1.65619
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 1.64796
F9 coagulation factor IX 1.64442
IL2 interleukin 2 1.64249
AKAP7 A kinase (PRKA) anchor protein 7 1.63701
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.62576
HAUS8 HAUS augmin-like complex, subunit 8 1.62569
ASGR1 asialoglycoprotein receptor 1 1.62459
NCKAP1L NCK-associated protein 1-like 1.62129
CD151 CD151 molecule (Raph blood group) 1.60965
S100A4 S100 calcium binding protein A4 1.60606
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.60499
CNIH4 cornichon family AMPA receptor auxiliary protein 4 1.60339
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 1.59422
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.59074
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 1.57162
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.5602
VAMP7 vesicle-associated membrane protein 7 1.55717
CLEC4D C-type lectin domain family 4, member D 1.55288
HIST2H2AB histone cluster 2, H2ab 1.55148
FOXA2 forkhead box A2 1.55118
EXOSC5 exosome component 5 1.54941
AURKB aurora kinase B 1.54805
NRK Nik related kinase 1.54665
WDR81 WD repeat domain 81 1.54169
SLC30A3 solute carrier family 30 (zinc transporter), member 3 1.53052
MAD2L1BP MAD2L1 binding protein 1.52974
RPP30 ribonuclease P/MRP 30kDa subunit 1.52717
FAM173A family with sequence similarity 173, member A 1.52317
EYA4 EYA transcriptional coactivator and phosphatase 4 1.52038
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.51288
RAD51 RAD51 recombinase 1.50437
PIP prolactin-induced protein 1.49878
IFT46 intraflagellar transport 46 1.49502
BOLA3 bolA family member 3 1.48744
RPS17 ribosomal protein S17 1.48391
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.48009
ITPKB inositol-trisphosphate 3-kinase B 1.47608
RPAP3 RNA polymerase II associated protein 3 1.47432
TGFBR1 transforming growth factor, beta receptor 1 1.47204
ANXA1 annexin A1 1.46688
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 1.46058
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.45722
CPD carboxypeptidase D 1.45437
PCDHA10 protocadherin alpha 10 1.44762
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.44553
INADL InaD-like (Drosophila) 1.43038
EYA3 EYA transcriptional coactivator and phosphatase 3 1.42906
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1.42268
PAH phenylalanine hydroxylase 1.40612
NEUROD1 neuronal differentiation 1 1.40077
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.39912
SYT2 synaptotagmin II 1.39901
FAM83H family with sequence similarity 83, member H 1.39729
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.38989
CASC3 cancer susceptibility candidate 3 1.38634
UBE2F ubiquitin-conjugating enzyme E2F (putative) 1.38288
ARHGAP12 Rho GTPase activating protein 12 1.38001
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.37909
LEPR leptin receptor 1.3787
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.37629
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.3628
RRAD Ras-related associated with diabetes 1.3586
PEX11B peroxisomal biogenesis factor 11 beta 1.35188
SUGP2 SURP and G patch domain containing 2 1.34849
TMEM5 transmembrane protein 5 1.34837
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.34802
MTMR1 myotubularin related protein 1 1.3454
HK2 hexokinase 2 1.34374
COG5 component of oligomeric golgi complex 5 1.34168
PADI2 peptidyl arginine deiminase, type II 1.33989
FLNB filamin B, beta 1.33687
FTO fat mass and obesity associated 1.33533
IL1RN interleukin 1 receptor antagonist 1.335
MRPL38 mitochondrial ribosomal protein L38 1.3348
FES FES proto-oncogene, tyrosine kinase 1.33024
PLA2G10 phospholipase A2, group X 1.32871
FPR2 formyl peptide receptor 2 1.3268
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.32298
CTSC cathepsin C 1.32259
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.32115
TM7SF3 transmembrane 7 superfamily member 3 1.31717
TM9SF3 transmembrane 9 superfamily member 3 1.31677
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.30735
AFP alpha-fetoprotein 1.30503
PTCH1 patched 1 1.30492
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.30364
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.30234
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.29705
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.28939
PDLIM7 PDZ and LIM domain 7 (enigma) 1.28734
LEPROT leptin receptor overlapping transcript 1.28426
ZCCHC6 zinc finger, CCHC domain containing 6 1.28138
PAM peptidylglycine alpha-amidating monooxygenase 1.27612
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 1.27097
TRAM1 translocation associated membrane protein 1 1.26833
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.26803
PCDH7 protocadherin 7 1.26221
LTA lymphotoxin alpha 1.25856
FBLN1 fibulin 1 1.25745
IMMT inner membrane protein, mitochondrial 1.25399
GTF3A general transcription factor IIIA 1.24897
ARNT aryl hydrocarbon receptor nuclear translocator 1.24818
FBXO6 F-box protein 6 1.2463
MYPOP Myb-related transcription factor, partner of profilin 1.24612
EN2 engrailed homeobox 2 1.2443
RP9 retinitis pigmentosa 9 (autosomal dominant) 1.24061
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.23995
NTF3 neurotrophin 3 1.23899
STAR steroidogenic acute regulatory protein 1.23899
MDM4 MDM4, p53 regulator 1.23518
PROX1 prospero homeobox 1 1.23447
IVD isovaleryl-CoA dehydrogenase 1.23369
PF4 platelet factor 4 1.23251
MATN2 matrilin 2 1.23241
PHKG1 phosphorylase kinase, gamma 1 (muscle) 1.23144
CHMP4C charged multivesicular body protein 4C 1.22932
IL12B interleukin 12B 1.22751
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.2221
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.21567
PCSK5 proprotein convertase subtilisin/kexin type 5 1.21515
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.21232
MARK3 MAP/microtubule affinity-regulating kinase 3 1.21015
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.20996
MARVELD1 MARVEL domain containing 1 1.2052
SAA2-SAA4 SAA2-SAA4 readthrough 1.20445
ANGPTL2 angiopoietin-like 2 1.20257
NPNT nephronectin 1.20204
WEE1 WEE1 G2 checkpoint kinase 1.2009
CCR8 chemokine (C-C motif) receptor 8 1.19964
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.19751
HMGB4 high mobility group box 4 1.19642
MARK1 MAP/microtubule affinity-regulating kinase 1 1.19604
BCHE butyrylcholinesterase 1.19467
MAT2B methionine adenosyltransferase II, beta 1.19272
ASF1B anti-silencing function 1B histone chaperone 1.19093
SIX4 SIX homeobox 4 1.18625
NCK1 NCK adaptor protein 1 1.18248
NT5DC3 5'-nucleotidase domain containing 3 1.18188
SPATA6 spermatogenesis associated 6 1.17562
FRYL FRY-like 1.17358
VDAC2 voltage-dependent anion channel 2 1.17116
RIOK3 RIO kinase 3 1.17075
MFAP4 microfibrillar-associated protein 4 1.1694
ZFP30 ZFP30 zinc finger protein 1.16691
RBM38 RNA binding motif protein 38 1.1659
ATOH7 atonal homolog 7 (Drosophila) 1.16082
TAPBP TAP binding protein (tapasin) 1.16037
IFRD2 interferon-related developmental regulator 2 1.15902
PEBP1 phosphatidylethanolamine binding protein 1 1.15876
CIZ1 CDKN1A interacting zinc finger protein 1 1.15826
RAB33B RAB33B, member RAS oncogene family 1.15736
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.15703
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.15667
NUDCD2 NudC domain containing 2 1.15075
CCNT1 cyclin T1 1.14846
ERLIN1 ER lipid raft associated 1 1.14788
F12 coagulation factor XII (Hageman factor) 1.14227
ADAM9 ADAM metallopeptidase domain 9 1.13861
HDAC7 histone deacetylase 7 1.13631
RGS11 regulator of G-protein signaling 11 1.13557
TMPO thymopoietin 1.12785
PTCRA pre T-cell antigen receptor alpha 1.12598
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.12539
HSF4 heat shock transcription factor 4 1.12456
BCAR1 breast cancer anti-estrogen resistance 1 1.12286
EPCAM epithelial cell adhesion molecule 1.12258
TUBGCP3 tubulin, gamma complex associated protein 3 1.12006
SNX9 sorting nexin 9 1.11977
TRIAP1 TP53 regulated inhibitor of apoptosis 1 1.11526
APRT adenine phosphoribosyltransferase 1.11394
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.1095
VDAC1 voltage-dependent anion channel 1 1.10856
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.10834
TFCP2 transcription factor CP2 1.10813
PCSK7 proprotein convertase subtilisin/kexin type 7 1.10748
LAMB1 laminin, beta 1 1.10711
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.10603
ART1 ADP-ribosyltransferase 1 1.10143
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.09904
NDP Norrie disease (pseudoglioma) 1.09594

decreased expression

Symbol Name Standardized Value
DCPS decapping enzyme, scavenger -4.83966
AHI1 Abelson helper integration site 1 -4.32572
TK2 thymidine kinase 2, mitochondrial -3.89907
DTX2 deltex 2, E3 ubiquitin ligase -3.64271
RTKN rhotekin -3.62305
BRCA2 breast cancer 2, early onset -3.6208
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -3.34559
TUBB4B tubulin, beta 4B class IVb -3.32964
PGLYRP1 peptidoglycan recognition protein 1 -3.27981
CUL1 cullin 1 -3.12664
GYG1 glycogenin 1 -3.01036
MRPS16 mitochondrial ribosomal protein S16 -2.91819
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.90295
C16ORF74 chromosome 16 open reading frame 74 -2.87044
UBN1 ubinuclein 1 -2.84992
PIGX phosphatidylinositol glycan anchor biosynthesis, class X -2.8166
C9ORF69 chromosome 9 open reading frame 69 -2.78549
STX8 syntaxin 8 -2.77766
MAP2K2 mitogen-activated protein kinase kinase 2 -2.75706
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.59923
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.59376
CST3 cystatin C -2.36933
MRPL40 mitochondrial ribosomal protein L40 -2.31356
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.30769
HLA-G major histocompatibility complex, class I, G -2.25203
TNS2 tensin 2 -2.24062
MRPL21 mitochondrial ribosomal protein L21 -2.22076
ACVRL1 activin A receptor type II-like 1 -2.21681
MAL mal, T-cell differentiation protein -2.14845
TMEM50B transmembrane protein 50B -2.12509
RUFY1 RUN and FYVE domain containing 1 -2.08266
HK1 hexokinase 1 -2.0658
NFE2L2 nuclear factor, erythroid 2-like 2 -2.05981
RIOK1 RIO kinase 1 -2.01868
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -1.97351
KRTCAP2 keratinocyte associated protein 2 -1.94546
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -1.9436
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.93921
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -1.93768
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.92497
UBE2W ubiquitin-conjugating enzyme E2W (putative) -1.90385
JAK2 Janus kinase 2 -1.89163
MAU2 MAU2 sister chromatid cohesion factor -1.88299
PBX2 pre-B-cell leukemia homeobox 2 -1.87159
USP21 ubiquitin specific peptidase 21 -1.86364
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -1.85484
TSPAN31 tetraspanin 31 -1.8242
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -1.81768
STARD3 StAR-related lipid transfer (START) domain containing 3 -1.79816
MYL9 myosin, light chain 9, regulatory -1.78833
DPCD deleted in primary ciliary dyskinesia homolog (mouse) -1.77321
FAM73B family with sequence similarity 73, member B -1.75241
EPX eosinophil peroxidase -1.73641
FGF17 fibroblast growth factor 17 -1.71989
TM2D2 TM2 domain containing 2 -1.71877
EIF5B eukaryotic translation initiation factor 5B -1.71406
FBXW4 F-box and WD repeat domain containing 4 -1.70021
TPP2 tripeptidyl peptidase II -1.68415
ARFIP2 ADP-ribosylation factor interacting protein 2 -1.68137
CSF1R colony stimulating factor 1 receptor -1.68042
FABP6 fatty acid binding protein 6, ileal -1.66738
SPHK2 sphingosine kinase 2 -1.65478
PTK7 protein tyrosine kinase 7 (inactive) -1.65372
NOP2 NOP2 nucleolar protein -1.65108
FHL1 four and a half LIM domains 1 -1.6445
PTEN phosphatase and tensin homolog -1.64038
TPD52L2 tumor protein D52-like 2 -1.61915
GLDC glycine dehydrogenase (decarboxylating) -1.61153
SSBP1 single-stranded DNA binding protein 1, mitochondrial -1.60412
KLC1 kinesin light chain 1 -1.58965
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.58765
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -1.58128
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.57011
HMGB2 high mobility group box 2 -1.56044
UBE2T ubiquitin-conjugating enzyme E2T -1.55665
APOD apolipoprotein D -1.54875
NDRG2 NDRG family member 2 -1.54709
CTSW cathepsin W -1.53437
OSBPL5 oxysterol binding protein-like 5 -1.51233
PBRM1 polybromo 1 -1.51026
NUCB1 nucleobindin 1 -1.50942
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -1.50283
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.50138
EXOC7 exocyst complex component 7 -1.50082
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -1.49404
RABGGTB Rab geranylgeranyltransferase, beta subunit -1.49324
PQBP1 polyglutamine binding protein 1 -1.49292
CHMP7 charged multivesicular body protein 7 -1.49176
APOA4 apolipoprotein A-IV -1.49016
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.48867
TBX3 T-box 3 -1.48753
FXR2 fragile X mental retardation, autosomal homolog 2 -1.47864
MYH9 myosin, heavy chain 9, non-muscle -1.4699
PTGIS prostaglandin I2 (prostacyclin) synthase -1.46967
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -1.46637
PRIM2 primase, DNA, polypeptide 2 (58kDa) -1.46253
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.45761
ARPC5L actin related protein 2/3 complex, subunit 5-like -1.45579
GM2A GM2 ganglioside activator -1.44761
CYBA cytochrome b-245, alpha polypeptide -1.4436
WNK2 WNK lysine deficient protein kinase 2 -1.43184
GREM2 gremlin 2, DAN family BMP antagonist -1.42852
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.42658
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -1.42108
GAS7 growth arrest-specific 7 -1.41966
MAG myelin associated glycoprotein -1.41807
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.40792
NKAIN1 Na+/K+ transporting ATPase interacting 1 -1.40567
PROSC proline synthetase co-transcribed homolog (bacterial) -1.40428
REL v-rel avian reticuloendotheliosis viral oncogene homolog -1.39249
NASP nuclear autoantigenic sperm protein (histone-binding) -1.38962
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -1.37725
ATOH1 atonal homolog 1 (Drosophila) -1.37527
MYO1D myosin ID -1.3607
GCH1 GTP cyclohydrolase 1 -1.35634
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -1.35309
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -1.34578
MOS v-mos Moloney murine sarcoma viral oncogene homolog -1.34271
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) -1.34053
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -1.31369
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -1.30619
IREB2 iron-responsive element binding protein 2 -1.30505
FAM136A family with sequence similarity 136, member A -1.30503
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -1.30087
C8ORF33 chromosome 8 open reading frame 33 -1.2989
GML glycosylphosphatidylinositol anchored molecule like -1.2962
NAV2 neuron navigator 2 -1.296
S100A3 S100 calcium binding protein A3 -1.29409
MTF1 metal-regulatory transcription factor 1 -1.28442
TLE3 transducin-like enhancer of split 3 -1.28299
CCBL2 cysteine conjugate-beta lyase 2 -1.28224
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -1.27952
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.27304
EFNB1 ephrin-B1 -1.26616
ATXN7L3B ataxin 7-like 3B -1.25157
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.24884
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -1.24792
PRPF31 pre-mRNA processing factor 31 -1.244
AHR aryl hydrocarbon receptor -1.23398
RAB3B RAB3B, member RAS oncogene family -1.2336
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -1.23133
GGCX gamma-glutamyl carboxylase -1.22803
SRXN1 sulfiredoxin 1 -1.22474
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -1.21835
RPA1 replication protein A1, 70kDa -1.21479
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -1.21313
DHRS7 dehydrogenase/reductase (SDR family) member 7 -1.21185
RBM6 RNA binding motif protein 6 -1.21128
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -1.20438
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -1.20065
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -1.19758
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -1.19225
SRA1 steroid receptor RNA activator 1 -1.18412
AOX1 aldehyde oxidase 1 -1.18403
FRZB frizzled-related protein -1.18284
CD82 CD82 molecule -1.1811
PNLIPRP2 pancreatic lipase-related protein 2 -1.17415
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -1.17387
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -1.17387
HAS1 hyaluronan synthase 1 -1.1702
HADH hydroxyacyl-CoA dehydrogenase -1.17006
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.16476
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -1.16472
NSG1 neuron specific gene family member 1 -1.15742
TSPAN6 tetraspanin 6 -1.15701
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.15416
C12ORF45 chromosome 12 open reading frame 45 -1.14383
HOXD3 homeobox D3 -1.14224
FECH ferrochelatase -1.13814
HAL histidine ammonia-lyase -1.13555
APOE apolipoprotein E -1.12834
STK11IP serine/threonine kinase 11 interacting protein -1.12698
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.12447
NCBP2 nuclear cap binding protein subunit 2, 20kDa -1.12148
MDN1 MDN1, midasin homolog (yeast) -1.1211
ENDOG endonuclease G -1.11928
GDF5 growth differentiation factor 5 -1.11867
HABP2 hyaluronan binding protein 2 -1.11827
HIST1H3C histone cluster 1, H3c -1.11768
ARL14EP ADP-ribosylation factor-like 14 effector protein -1.11741
SELENBP1 selenium binding protein 1 -1.11347
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.10944
VWF von Willebrand factor -1.10864
HS1BP3 HCLS1 binding protein 3 -1.10535
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.10402
S100B S100 calcium binding protein B -1.10125
PYGO2 pygopus family PHD finger 2 -1.10124
PSMC3IP PSMC3 interacting protein -1.10024
ACSF3 acyl-CoA synthetase family member 3 -1.09891
CLEC4E C-type lectin domain family 4, member E -1.09651
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.08846
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) -1.08156
ACTA1 actin, alpha 1, skeletal muscle -1.07444
FMOD fibromodulin -1.07429
WNT4 wingless-type MMTV integration site family, member 4 -1.07053
EXOSC4 exosome component 4 -1.06919
ATG7 autophagy related 7 -1.0652
SOX17 SRY (sex determining region Y)-box 17 -1.0604
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.05212
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -1.05097
MSH2 mutS homolog 2 -1.05037
ZFP57 ZFP57 zinc finger protein -1.05011
HAX1 HCLS1 associated protein X-1 -1.04961
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -1.04895
COX5A cytochrome c oxidase subunit Va -1.04893
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -1.03889
HPCAL4 hippocalcin like 4 -1.0367
ART5 ADP-ribosyltransferase 5 -1.03666
HIST1H3J histone cluster 1, H3j -1.03516
APOB apolipoprotein B -1.03436
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.02745
USO1 USO1 vesicle transport factor -1.02549
LGALS9B lectin, galactoside-binding, soluble, 9B -1.02516
NOTCH4 notch 4 -1.02243
LIMCH1 LIM and calponin homology domains 1 -1.02051
URM1 ubiquitin related modifier 1 -1.0192
PHTF1 putative homeodomain transcription factor 1 -1.01183
DSP desmoplakin -1.01147
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.01108
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -1.01035
KIAA2013 KIAA2013 -1.00803
ZFHX3 zinc finger homeobox 3 -1.00578
PREP prolyl endopeptidase -1.00522
EFHD1 EF-hand domain family, member D1 -1.00413
MRPL28 mitochondrial ribosomal protein L28 -0.998104
KDM5A lysine (K)-specific demethylase 5A -0.996557
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -0.994285
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -0.988558
FBXO15 F-box protein 15 -0.987363
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.986171
AMBP alpha-1-microglobulin/bikunin precursor -0.980821
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.974241
N4BP1 NEDD4 binding protein 1 -0.97089
MPEG1 macrophage expressed 1 -0.970243
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 -0.970132
PLA2G5 phospholipase A2, group V -0.964988
HSPA4 heat shock 70kDa protein 4 -0.962457
UBFD1 ubiquitin family domain containing 1 -0.957801
C12ORF10 chromosome 12 open reading frame 10 -0.956091
LTB lymphotoxin beta (TNF superfamily, member 3) -0.955741
HIST1H1C histone cluster 1, H1c -0.955182
LMO1 LIM domain only 1 (rhombotin 1) -0.953837
C1ORF86 chromosome 1 open reading frame 86 -0.951364
COQ4 coenzyme Q4 -0.951305
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -0.950486
TP53I13 tumor protein p53 inducible protein 13 -0.945989
MRFAP1 Morf4 family associated protein 1 -0.945872
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.945387
PDE4DIP phosphodiesterase 4D interacting protein -0.944229
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.942971
SNTA1 syntrophin, alpha 1 -0.940244
FGF1 fibroblast growth factor 1 (acidic) -0.936734
MR1 major histocompatibility complex, class I-related -0.934758
CIT citron rho-interacting serine/threonine kinase -0.934084
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.93307
RHOA ras homolog family member A -0.930984
UBE2Z ubiquitin-conjugating enzyme E2Z -0.927959
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.924362
KRT25 keratin 25, type I -0.922784
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -0.91908
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.917638
FCRLA Fc receptor-like A -0.916837
SOX1 SRY (sex determining region Y)-box 1 -0.914032
NCF2 neutrophil cytosolic factor 2 -0.911736
KIF23 kinesin family member 23 -0.91141
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.911091
CRCP CGRP receptor component -0.907131
C9ORF89 chromosome 9 open reading frame 89 -0.906561
FXYD5 FXYD domain containing ion transport regulator 5 -0.906109
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.904436
AKTIP AKT interacting protein -0.902973
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -0.901889
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -0.901624
IQGAP1 IQ motif containing GTPase activating protein 1 -0.901301
ODC1 ornithine decarboxylase 1 -0.898483
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 -0.897881
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -0.895871
RFC2 replication factor C (activator 1) 2, 40kDa -0.894554
THOC7 THO complex 7 -0.893315
PID1 phosphotyrosine interaction domain containing 1 -0.892499
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.890611
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -0.888797
NUP107 nucleoporin 107kDa -0.888543
P4HB prolyl 4-hydroxylase, beta polypeptide -0.886502
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -0.884613
ACOT13 acyl-CoA thioesterase 13 -0.883634
MKI67 marker of proliferation Ki-67 -0.882392
PCGF2 polycomb group ring finger 2 -0.880621
INVS inversin -0.878362
EMC8 ER membrane protein complex subunit 8 -0.878089
TCTA T-cell leukemia translocation altered -0.876164
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.874501
MEPCE methylphosphate capping enzyme -0.871171
NPTX2 neuronal pentraxin II -0.870908
PTTG1 pituitary tumor-transforming 1 -0.86912
TBL1X transducin (beta)-like 1X-linked -0.866377
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.863244
CNR2 cannabinoid receptor 2 (macrophage) -0.86184
SF3A1 splicing factor 3a, subunit 1, 120kDa -0.860268
FRMD5 FERM domain containing 5 -0.859522
Funding