| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyfasudil perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyfasudil_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.368967 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.253719 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125735 |
| TMC5 | transmembrane channel-like 5 | 0.097312 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0658666 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0600305 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0598313 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.059274 |
| LMO7 | LIM domain 7 | 0.0559011 |
| LCN2 | lipocalin 2 | 0.0544582 |
| DSPP | dentin sialophosphoprotein | 0.0507476 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0495461 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0495431 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0482154 |
| ANXA1 | annexin A1 | 0.0473177 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0460786 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0408112 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0403899 |
| SIK3 | SIK family kinase 3 | 0.0374437 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.035954 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0343495 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0316142 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0307745 |
| UBB | ubiquitin B | 0.0303161 |
| AFDN | afadin, adherens junction formation factor | 0.0303081 |
| SPATA13 | spermatogenesis associated 13 | 0.0301455 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0300699 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0299339 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0297995 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0293178 |
| MYO1E | myosin IE | 0.0290632 |
| RPL26 | ribosomal protein L26 | 0.0289767 |
| RPS17 | ribosomal protein S17 | 0.0286765 |
| HDAC9 | histone deacetylase 9 | 0.0286108 |
| RPS3 | ribosomal protein S3 | 0.0285194 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279982 |
| POF1B | premature ovarian failure, 1B | 0.0264231 |
| FOXP1 | forkhead box P1 | 0.0263468 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0263167 |
| CDK6 | cyclin-dependent kinase 6 | 0.0262335 |
| SHROOM3 | shroom family member 3 | 0.026021 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.025738 |
| EZR | ezrin | 0.0254812 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0253377 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0250257 |
| SP100 | SP100 nuclear antigen | 0.0248414 |
| RNF213 | ring finger protein 213 | 0.0245333 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0244532 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0240234 |
| UBC | ubiquitin C | 0.0237081 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0235964 |
| ETV6 | ets variant 6 | 0.0233542 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.023302 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0232113 |
| RPL18 | ribosomal protein L18 | 0.0223848 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0222519 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0222073 |
| SET | SET nuclear proto-oncogene | 0.022111 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0220162 |
| GOLGB1 | golgin B1 | 0.0219831 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219756 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0219105 |
| CCDC146 | coiled-coil domain containing 146 | 0.0218743 |
| RPL21 | ribosomal protein L21 | 0.0211119 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0210889 |
| GDA | guanine deaminase | 0.0209474 |
| ITGB8 | integrin, beta 8 | 0.0209286 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0208382 |
| KIF16B | kinesin family member 16B | 0.0208274 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0208274 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0207659 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0207241 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0206839 |
| PHF3 | PHD finger protein 3 | 0.0205246 |
| TMEM45B | transmembrane protein 45B | 0.0203104 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0202044 |
| DST | dystonin | 0.0201049 |
| MCU | mitochondrial calcium uniporter | 0.0200793 |
| MYO9A | myosin IXA | 0.0200052 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0199742 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0199179 |
| ZNF292 | zinc finger protein 292 | 0.0199101 |
| EXOC6B | exocyst complex component 6B | 0.0198978 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0198268 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.019755 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0197419 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.0196448 |
| RPS12 | ribosomal protein S12 | 0.0195361 |
| AGR3 | anterior gradient 3 | 0.0193113 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0186692 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0186456 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0185648 |
| COBL | cordon-bleu WH2 repeat protein | 0.0183386 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0182901 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | 0.0182063 |
| SEPTIN9 | septin 9 | 0.0181892 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0181754 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0181729 |
| RRBP1 | ribosome binding protein 1 | 0.0180222 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0178113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.194941 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.173309 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109351 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.103461 |
| NPSR1 | neuropeptide S receptor 1 | -0.0988719 |
| S100A6 | S100 calcium binding protein A6 | -0.0863863 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0857094 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0747048 |
| RPL35A | ribosomal protein L35a | -0.0733734 |
| TMSB10 | thymosin beta 10 | -0.0728076 |
| NDRG1 | N-myc downstream regulated 1 | -0.0669503 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0655873 |
| AGR2 | anterior gradient 2 | -0.0653056 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0648102 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0642482 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0630551 |
| ANLN | anillin, actin binding protein | -0.0615822 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0606836 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0568277 |
| POTEF | POTE ankyrin domain family, member F | -0.0565607 |
| PKM | pyruvate kinase, muscle | -0.0547439 |
| S100A10 | S100 calcium binding protein A10 | -0.0543154 |
| ANXA2 | annexin A2 | -0.0537714 |
| PTMA | prothymosin, alpha | -0.053107 |
| KRT18 | keratin 18, type I | -0.0507911 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0492113 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0486484 |
| AREG | amphiregulin | -0.0470473 |
| FLNB | filamin B, beta | -0.0469342 |
| CALR | calreticulin | -0.0469219 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0451433 |
| CLDN7 | claudin 7 | -0.0448623 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0429094 |
| KRT8 | keratin 8, type II | -0.0419904 |
| INSIG1 | insulin induced gene 1 | -0.0419735 |
| TMEM123 | transmembrane protein 123 | -0.0404576 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0382528 |
| H1-0 | H1.0 linker histone | -0.037992 |
| EMP1 | epithelial membrane protein 1 | -0.0377778 |
| ACTG1 | actin gamma 1 | -0.037543 |
| TPM4 | tropomyosin 4 | -0.0370387 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0366708 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0364113 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0363147 |
| WDR45B | WD repeat domain 45B | -0.0360565 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0360177 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0359057 |
| DEK | DEK proto-oncogene | -0.0353962 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0349733 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0346594 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0346192 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0338103 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0337463 |
| HYOU1 | hypoxia up-regulated 1 | -0.0327736 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0324514 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0323683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0322879 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0321176 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0320305 |
| XPO1 | exportin 1 | -0.031767 |
| S100A9 | S100 calcium binding protein A9 | -0.0316242 |
| MKI67 | marker of proliferation Ki-67 | -0.0314545 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0313718 |
| CLTC | clathrin, heavy chain (Hc) | -0.0312937 |
| ACTN4 | actinin, alpha 4 | -0.0311749 |
| HM13 | histocompatibility (minor) 13 | -0.0307017 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0305749 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0304788 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0301238 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0299293 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0298803 |
| BCL2L1 | BCL2-like 1 | -0.0290734 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0290378 |
| HMGA1 | high mobility group AT-hook 1 | -0.0289822 |
| ECT2 | epithelial cell transforming 2 | -0.0287286 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0286583 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283522 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0281871 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0281314 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0279265 |
| RTN4 | reticulon 4 | -0.0278622 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0278085 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0276913 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0274009 |
| CTBP2 | C-terminal binding protein 2 | -0.0272023 |
| LYZ | lysozyme | -0.0270551 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.026785 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0267761 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0267244 |
| VEGFA | vascular endothelial growth factor A | -0.0265887 |
| FAT1 | FAT atypical cadherin 1 | -0.0263061 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0262325 |
| KLK10 | kallikrein-related peptidase 10 | -0.0260982 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.0256584 |
| RPS24 | ribosomal protein S24 | -0.0255053 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0254798 |
| PGK1 | phosphoglycerate kinase 1 | -0.025392 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0252621 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0251102 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.025003 |
