| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyfasudil perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hydroxyfasudil_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.255575 |
| VIM | vimentin | 0.179828 |
| PCBP2 | poly(rC) binding protein 2 | 0.109111 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106326 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0913244 |
| ENO1 | enolase 1, (alpha) | 0.0851281 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0792168 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0713951 |
| ANGPTL4 | angiopoietin-like 4 | 0.0696049 |
| RPS6 | ribosomal protein S6 | 0.0662341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0655497 |
| CDCP1 | CUB domain containing protein 1 | 0.0639745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0592321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0582301 |
| NAV2 | neuron navigator 2 | 0.0580436 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0559011 |
| CA12 | carbonic anhydrase XII | 0.0556934 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0531665 |
| CD44 | CD44 molecule (Indian blood group) | 0.0529187 |
| MAP1B | microtubule-associated protein 1B | 0.0514352 |
| FAM13A | family with sequence similarity 13, member A | 0.0512373 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0497534 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0480705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0471195 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0466512 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0462182 |
| RPS12 | ribosomal protein S12 | 0.0453335 |
| STC1 | stanniocalcin 1 | 0.0451717 |
| MYADM | myeloid-associated differentiation marker | 0.0448441 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0443128 |
| FN1 | fibronectin 1 | 0.0438879 |
| LDHA | lactate dehydrogenase A | 0.0432979 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0426197 |
| EHBP1 | EH domain binding protein 1 | 0.0425506 |
| PLIN2 | perilipin 2 | 0.0421123 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0419747 |
| RPS3 | ribosomal protein S3 | 0.0412562 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0410287 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0409192 |
| B2M | beta-2-microglobulin | 0.0400237 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0396762 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0390581 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0383256 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0378383 |
| BPTF | bromodomain PHD finger transcription factor | 0.0374934 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0366862 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0363573 |
| IL1B | interleukin 1, beta | 0.0363081 |
| ASPH | aspartate beta-hydroxylase | 0.0361695 |
| EGFR | epidermal growth factor receptor | 0.0354462 |
| RPS8 | ribosomal protein S8 | 0.0349648 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0342297 |
| RPL3 | ribosomal protein L3 | 0.0341637 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.033588 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335525 |
| FNIP1 | folliculin interacting protein 1 | 0.0329874 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0322854 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.032075 |
| LOXL2 | lysyl oxidase-like 2 | 0.0319073 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0317895 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0317096 |
| HDAC9 | histone deacetylase 9 | 0.0312669 |
| SQSTM1 | sequestosome 1 | 0.0306754 |
| VEGFA | vascular endothelial growth factor A | 0.0304858 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0304714 |
| MCL1 | myeloid cell leukemia 1 | 0.0303095 |
| NRP1 | neuropilin 1 | 0.0300154 |
| VMP1 | vacuole membrane protein 1 | 0.0299206 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0298752 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0297826 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0296329 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0292963 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0286903 |
| UBXN4 | UBX domain protein 4 | 0.0286764 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0284812 |
| TGM2 | transglutaminase 2 | 0.0282469 |
| WLS | wntless Wnt ligand secretion mediator | 0.0281308 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0277607 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274695 |
| GOLGA4 | golgin A4 | 0.0274361 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0273828 |
| RND3 | Rho family GTPase 3 | 0.0270643 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0269896 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0269796 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0268237 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0262703 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0260201 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0259746 |
| OPTN | optineurin | 0.0258817 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0254287 |
| TPM3 | tropomyosin 3 | 0.0253986 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0253945 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0251898 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0250431 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0246715 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0244869 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0243849 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0243077 |
| LRRC49 | leucine rich repeat containing 49 | 0.0241485 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.247253 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.168016 |
| CDH13 | cadherin 13 | -0.0918707 |
| RBM39 | RNA binding motif protein 39 | -0.090683 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0902274 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0866167 |
| GLCCI1 | glucocorticoid induced 1 | -0.0834075 |
| FAM20C | family with sequence similarity 20, member C | -0.0699773 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0694337 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0670481 |
| TMSB10 | thymosin beta 10 | -0.0656259 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0534905 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.051814 |
| GNAS | GNAS complex locus | -0.0504287 |
| IER3 | immediate early response 3 | -0.0487335 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0476231 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0453048 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0443555 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0432492 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0423877 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0400065 |
| VCL | vinculin | -0.0391259 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0385798 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0380274 |
| ZNF804A | zinc finger protein 804A | -0.0377161 |
| MECOM | MDS1 and EVI1 complex locus | -0.0373361 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0367136 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0364847 |
| SPAG9 | sperm associated antigen 9 | -0.0364634 |
| TMEM263 | transmembrane protein 263 | -0.0363788 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350756 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0350733 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0349049 |
| CDK14 | cyclin-dependent kinase 14 | -0.0348256 |
| FUS | FUS RNA binding protein | -0.0346992 |
| RPLP1 | ribosomal protein, large, P1 | -0.0346219 |
| NUMB | numb homolog (Drosophila) | -0.034468 |
| NRG1 | neuregulin 1 | -0.0340068 |
| SP100 | SP100 nuclear antigen | -0.0338316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0337792 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0336686 |
| INTS6 | integrator complex subunit 6 | -0.0333937 |
| FOXO3 | forkhead box O3 | -0.0330437 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0328874 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0326678 |
| SMAD2 | SMAD family member 2 | -0.0325701 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0321058 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0319302 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.031687 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0312364 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0312191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0311351 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0310498 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0309334 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0308314 |
| MORF4L2 | mortality factor 4 like 2 | -0.0307335 |
| USP3 | ubiquitin specific peptidase 3 | -0.0303157 |
| RIGI | RNA sensor RIG-I | -0.0295783 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.029486 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0291963 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0291874 |
| PARD3 | par-3 family cell polarity regulator | -0.0289601 |
| NF1 | neurofibromin 1 | -0.0289512 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0285693 |
| WDR45B | WD repeat domain 45B | -0.028448 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0281597 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.028134 |
| QKI | QKI, KH domain containing, RNA binding | -0.0277385 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.027664 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0273651 |
| CUL3 | cullin 3 | -0.0272458 |
| CTBP2 | C-terminal binding protein 2 | -0.0271074 |
| SEC24D | SEC24 family member D | -0.0269866 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0267262 |
| DUSP16 | dual specificity phosphatase 16 | -0.0266398 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265866 |
| MAP4 | microtubule-associated protein 4 | -0.0264639 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0264477 |
| VRK2 | vaccinia related kinase 2 | -0.026424 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0261539 |
| FBXO11 | F-box protein 11 | -0.0261532 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0261445 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0261167 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0260793 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0257808 |
| MEF2A | myocyte enhancer factor 2A | -0.0257663 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0257353 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0256471 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255807 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0255383 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0254653 |
| EFNA5 | ephrin-A5 | -0.0254019 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0253653 |
| ANXA2 | annexin A2 | -0.0249703 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0249067 |
| CDC73 | cell division cycle 73 | -0.0246935 |
| TMSB4X | thymosin beta 4, X-linked | -0.0245684 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245486 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0240944 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0237927 |
