| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyfasudil perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hydroxyfasudil_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.227441 |
| NDRG1 | N-myc downstream regulated 1 | 0.146621 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.132775 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.126709 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.120262 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.113683 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.108276 |
| MYO1E | myosin IE | 0.104861 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0983446 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0973055 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0916362 |
| RORA | RAR-related orphan receptor A | 0.0847901 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0839632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0827911 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0827054 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0811451 |
| DST | dystonin | 0.0776118 |
| RPL15 | ribosomal protein L15 | 0.0772341 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0745972 |
| FNIP1 | folliculin interacting protein 1 | 0.0744302 |
| STC1 | stanniocalcin 1 | 0.0742813 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0732278 |
| RPS12 | ribosomal protein S12 | 0.0709253 |
| RPL11 | ribosomal protein L11 | 0.0707516 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0701008 |
| GRB10 | growth factor receptor-bound protein 10 | 0.069988 |
| FTL | ferritin, light polypeptide | 0.0675024 |
| B2M | beta-2-microglobulin | 0.0668816 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0638447 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0635922 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.0634522 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.062981 |
| JMJD1C | jumonji domain containing 1C | 0.0547869 |
| VCL | vinculin | 0.0526041 |
| GOLGA4 | golgin A4 | 0.0514909 |
| SQSTM1 | sequestosome 1 | 0.0504058 |
| ZNF292 | zinc finger protein 292 | 0.0504022 |
| SPAG9 | sperm associated antigen 9 | 0.0502882 |
| FLNB | filamin B, beta | 0.0487777 |
| RPLP1 | ribosomal protein, large, P1 | 0.0483317 |
| HDLBP | high density lipoprotein binding protein | 0.0452792 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.044551 |
| DSPP | dentin sialophosphoprotein | 0.0440253 |
| POTEF | POTE ankyrin domain family, member F | 0.0436151 |
| HDAC9 | histone deacetylase 9 | 0.043589 |
| LDHA | lactate dehydrogenase A | 0.0432689 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0422012 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0417777 |
| RPS3 | ribosomal protein S3 | 0.0410587 |
| STK24 | serine/threonine kinase 24 | 0.0393891 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0390188 |
| RAD51B | RAD51 paralog B | 0.0387017 |
| TOP1 | topoisomerase (DNA) I | 0.0386045 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0380822 |
| YBX3 | Y box binding protein 3 | 0.0348097 |
| RPS8 | ribosomal protein S8 | 0.0347969 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0341269 |
| H3-3B | H3.3 histone B | 0.0333994 |
| LMO7 | LIM domain 7 | 0.0327976 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0325948 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.032379 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0319908 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314219 |
| RPL38 | ribosomal protein L38 | 0.0304644 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0300117 |
| RPL23 | ribosomal protein L23 | 0.0289676 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0285217 |
| PRELID2 | PRELI domain containing 2 | 0.0278112 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.027282 |
| RPS4X | ribosomal protein S4, X-linked | 0.026706 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.026294 |
| SP100 | SP100 nuclear antigen | 0.0252831 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250096 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0248301 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0248208 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0245523 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0243539 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0240502 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.022381 |
| CUX1 | cut-like homeobox 1 | 0.0213847 |
| CD44 | CD44 molecule (Indian blood group) | 0.0205378 |
| MYOF | myoferlin | 0.0163212 |
| LMNA | lamin A/C | 0.0160063 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0159393 |
| RPL28 | ribosomal protein L28 | 0.0150304 |
| USP34 | ubiquitin specific peptidase 34 | 0.0149283 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0140671 |
| OXSR1 | oxidative stress responsive 1 | 0.0137646 |
| PKM | pyruvate kinase, muscle | 0.0134701 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0126137 |
| ATXN2 | ataxin 2 | 0.0124964 |
| RPS11 | ribosomal protein S11 | 0.0115614 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0115594 |
| RNF213 | ring finger protein 213 | 0.0115532 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.011389 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.011152 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0107277 |
| ARRDC3 | arrestin domain containing 3 | 0.00969878 |
| MYO6 | myosin VI | 0.00961194 |
| RBM26 | RNA binding motif protein 26 | 0.00875556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.216849 |
| VIM | vimentin | -0.139271 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.137097 |
| PRKCA | protein kinase C, alpha | -0.122517 |
| EFNA5 | ephrin-A5 | -0.119803 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113758 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.103777 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.102761 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0971956 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0918155 |
| EGFR | epidermal growth factor receptor | -0.091766 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0907908 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.088382 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0820995 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0797519 |
| RPL37A | ribosomal protein L37a | -0.0793171 |
| ENO1 | enolase 1, (alpha) | -0.0772559 |
| SLTM | SAFB-like, transcription modulator | -0.0737346 |
| OSMR | oncostatin M receptor | -0.071832 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0701085 |
| GPC6 | glypican 6 | -0.0694316 |
| MCL1 | myeloid cell leukemia 1 | -0.0671208 |
| RUNX1 | runt-related transcription factor 1 | -0.0671076 |
| VMP1 | vacuole membrane protein 1 | -0.0665302 |
| MAP4 | microtubule-associated protein 4 | -0.0649631 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0649358 |
| FNDC3B | fibronectin type III domain containing 3B | -0.063462 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0585818 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0584476 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0562028 |
| PDE8A | phosphodiesterase 8A | -0.0560279 |
| FMNL2 | formin-like 2 | -0.0540524 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0518059 |
| MT2A | metallothionein 2A | -0.0512911 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0512757 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0511463 |
| RPS6 | ribosomal protein S6 | -0.0507678 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0503609 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0497991 |
| ITGA6 | integrin, alpha 6 | -0.0477334 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0469071 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0464701 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0440827 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0439053 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0430679 |
| RBM39 | RNA binding motif protein 39 | -0.0428555 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0419464 |
| HELZ | helicase with zinc finger | -0.0404548 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0399836 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0382876 |
| RPL37 | ribosomal protein L37 | -0.0367647 |
| EHBP1 | EH domain binding protein 1 | -0.0361289 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0354354 |
| TMSB10 | thymosin beta 10 | -0.0351893 |
| RTN4 | reticulon 4 | -0.034001 |
| SMAD2 | SMAD family member 2 | -0.0317861 |
| ASPH | aspartate beta-hydroxylase | -0.0300922 |
| MYO10 | myosin X | -0.0298497 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0276617 |
| SEPTIN7 | septin 7 | -0.0261684 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0248768 |
| RNF145 | ring finger protein 145 | -0.0244766 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0231247 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0222699 |
| RPLP2 | ribosomal protein, large, P2 | -0.021909 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0216675 |
| PDE10A | phosphodiesterase 10A | -0.021328 |
| RPL7A | ribosomal protein L7a | -0.0203874 |
| AQR | aquarius intron-binding spliceosomal factor | -0.0203675 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0192119 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0188121 |
| ZNF644 | zinc finger protein 644 | -0.0186488 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0183547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0176819 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0170876 |
| FOXP1 | forkhead box P1 | -0.0170104 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0167592 |
| SBF2 | SET binding factor 2 | -0.0163215 |
| MAP7 | microtubule-associated protein 7 | -0.0161198 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0153571 |
| RSF1 | remodeling and spacing factor 1 | -0.0148141 |
| FOXN3 | forkhead box N3 | -0.0133478 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0122169 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0118588 |
| RAN | RAN, member RAS oncogene family | -0.0117757 |
| RPL9 | ribosomal protein L9 | -0.0111694 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0109021 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00992921 |
| RPL7 | ribosomal protein L7 | -0.00989852 |
| RYBP | RING1 and YY1 binding protein | -0.00964422 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.00959816 |
| TXNRD1 | thioredoxin reductase 1 | -0.00912093 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.00908011 |
| PAPOLA | poly(A) polymerase alpha | -0.00894625 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00894623 |
| RPL13A | ribosomal protein L13a | -0.00870097 |
| FRMD4A | FERM domain containing 4A | -0.0086391 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00832822 |
| PTK2 | protein tyrosine kinase 2 | -0.0079851 |
| TCF12 | transcription factor 12 | -0.00775926 |
