| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyfasudil perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hydroxyfasudil_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.200258 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.184064 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.137773 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0988464 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0811994 |
| NAV2 | neuron navigator 2 | 0.0756753 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0752889 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.072416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0669976 |
| CD44 | CD44 molecule (Indian blood group) | 0.066919 |
| RPS12 | ribosomal protein S12 | 0.0661495 |
| MSN | moesin | 0.0649177 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0597856 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0584414 |
| MT2A | metallothionein 2A | 0.0571249 |
| SMAD3 | SMAD family member 3 | 0.0526804 |
| RND3 | Rho family GTPase 3 | 0.0516417 |
| KYNU | kynureninase | 0.0503719 |
| SQSTM1 | sequestosome 1 | 0.050265 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0486753 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0481842 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0456927 |
| VEGFA | vascular endothelial growth factor A | 0.0456778 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0454542 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0448516 |
| GOLGB1 | golgin B1 | 0.0445784 |
| HDAC9 | histone deacetylase 9 | 0.0444744 |
| ENO1 | enolase 1, (alpha) | 0.0433555 |
| B2M | beta-2-microglobulin | 0.0429771 |
| RPL11 | ribosomal protein L11 | 0.0415561 |
| JMJD1C | jumonji domain containing 1C | 0.0410974 |
| VCAN | versican | 0.0407651 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0384763 |
| HLA-A | major histocompatibility complex, class I, A | 0.0383601 |
| C3 | complement component 3 | 0.0382924 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0376291 |
| VIM | vimentin | 0.0375226 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0373817 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0370087 |
| SFTPA2 | surfactant protein A2 | 0.0363771 |
| GPC6 | glypican 6 | 0.0351578 |
| UBC | ubiquitin C | 0.0347113 |
| BRD2 | bromodomain containing 2 | 0.0335156 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0334899 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0334896 |
| STC1 | stanniocalcin 1 | 0.0330845 |
| RPS2 | ribosomal protein S2 | 0.032688 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.032476 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322937 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0319326 |
| SDC4 | syndecan 4 | 0.0314901 |
| RPS6 | ribosomal protein S6 | 0.0314268 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0313822 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0312294 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0311984 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.031148 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.030665 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0301291 |
| FNIP1 | folliculin interacting protein 1 | 0.0297501 |
| CENPF | centromere protein F, 350/400kDa | 0.0295175 |
| RPL27 | ribosomal protein L27 | 0.0289531 |
| RPS3 | ribosomal protein S3 | 0.0284164 |
| CDK19 | cyclin-dependent kinase 19 | 0.0282089 |
| RPL21 | ribosomal protein L21 | 0.0280872 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0280013 |
| FBXO32 | F-box protein 32 | 0.0276036 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0267098 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0266784 |
| CALD1 | caldesmon 1 | 0.0266039 |
| RPS4X | ribosomal protein S4, X-linked | 0.0265933 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0265478 |
| PLPP6 | phospholipid phosphatase 6 | 0.0263269 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0262357 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0258532 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0254935 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0252229 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0250052 |
| APP | amyloid beta (A4) precursor protein | 0.0249669 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0247913 |
| PLSCR1 | phospholipid scramblase 1 | 0.0244266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.024257 |
| ATXN1 | ataxin 1 | 0.0241343 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0240716 |
| CEP250 | centrosomal protein 250kDa | 0.0240098 |
| FLOT1 | flotillin 1 | 0.0240007 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0239885 |
| FRMD5 | FERM domain containing 5 | 0.0238771 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0238684 |
| OSMR | oncostatin M receptor | 0.0238666 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0238287 |
| RPL3 | ribosomal protein L3 | 0.0237067 |
| RPL26 | ribosomal protein L26 | 0.0236887 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0236652 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0235944 |
| DUSP5 | dual specificity phosphatase 5 | 0.0235851 |
| FOXP1 | forkhead box P1 | 0.0235417 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0234795 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0234178 |
| BICC1 | BicC family RNA binding protein 1 | 0.0233642 |
| SON | SON DNA binding protein | 0.0233281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.133844 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124163 |
| IER3 | immediate early response 3 | -0.119048 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0954757 |
| RPS24 | ribosomal protein S24 | -0.0672541 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0670499 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.066048 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0638117 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0574078 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0555621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0553122 |
| GNAS | GNAS complex locus | -0.0509313 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0499525 |
| GLIS3 | GLIS family zinc finger 3 | -0.049691 |
| TMSB10 | thymosin beta 10 | -0.0491691 |
| PTMA | prothymosin, alpha | -0.0478782 |
| CANX | calnexin | -0.0474073 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0472621 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0462695 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0453716 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0450623 |
| HELZ | helicase with zinc finger | -0.041777 |
| HMGA2 | high mobility group AT-hook 2 | -0.0409868 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0407258 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0403376 |
| FN1 | fibronectin 1 | -0.0402064 |
| RBM39 | RNA binding motif protein 39 | -0.0387052 |
| CALR | calreticulin | -0.0378807 |
| COL5A1 | collagen, type V, alpha 1 | -0.0361458 |
| QKI | QKI, KH domain containing, RNA binding | -0.036138 |
| CDH13 | cadherin 13 | -0.0361088 |
| TFG | TRK-fused gene | -0.0357349 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0354765 |
| CADM1 | cell adhesion molecule 1 | -0.0349481 |
| INTS6 | integrator complex subunit 6 | -0.0337322 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0336607 |
| PDE10A | phosphodiesterase 10A | -0.033524 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327857 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0326666 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0323666 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0321534 |
| TMEM123 | transmembrane protein 123 | -0.0321485 |
| TMEM263 | transmembrane protein 263 | -0.0320984 |
| AHNAK | AHNAK nucleoprotein | -0.0320342 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0315895 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.031139 |
| RAI14 | retinoic acid induced 14 | -0.030684 |
| MORF4L2 | mortality factor 4 like 2 | -0.0304036 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0295565 |
| RPL35A | ribosomal protein L35a | -0.0292711 |
| ATP13A3 | ATPase type 13A3 | -0.0291385 |
| RYBP | RING1 and YY1 binding protein | -0.0283644 |
| ZNF207 | zinc finger protein 207 | -0.0280806 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0277158 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0272162 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0267668 |
| TMSB4X | thymosin beta 4, X-linked | -0.0264714 |
| NAV1 | neuron navigator 1 | -0.0264351 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262832 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0262112 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0259796 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0257262 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0254455 |
| TKT | transketolase | -0.0252025 |
| ABHD12 | abhydrolase domain containing 12 | -0.024865 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0243203 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0242611 |
| DTNA | dystrobrevin, alpha | -0.0241982 |
| NRN1 | neuritin 1 | -0.0240302 |
| SLC35F3 | solute carrier family 35, member F3 | -0.024005 |
| ANXA2 | annexin A2 | -0.0237676 |
| CLINT1 | clathrin interactor 1 | -0.0236543 |
| TUBB | tubulin, beta class I | -0.0236357 |
| FUS | FUS RNA binding protein | -0.0236125 |
| EFNA5 | ephrin-A5 | -0.0234953 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0234368 |
| FAM162A | family with sequence similarity 162, member A | -0.0233068 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0226634 |
| USP3 | ubiquitin specific peptidase 3 | -0.0226564 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0226467 |
| MAP4 | microtubule-associated protein 4 | -0.0225009 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0224905 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0223337 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0223111 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0220343 |
| CUL3 | cullin 3 | -0.0220033 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0215855 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0215826 |
| ARF1 | ADP-ribosylation factor 1 | -0.0215693 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0215335 |
| THBS2 | thrombospondin 2 | -0.0211574 |
| CUL4B | cullin 4B | -0.0210087 |
| PRRC1 | proline-rich coiled-coil 1 | -0.020984 |
| CAVIN1 | caveolae associated protein 1 | -0.0209796 |
| NCKAP5 | NCK-associated protein 5 | -0.0208166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0208151 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0207446 |
| SEC24D | SEC24 family member D | -0.0205444 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0202982 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0202928 |
