| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyfasudil perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyfasudil_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.182253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0902779 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0619635 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0571759 |
| SQSTM1 | sequestosome 1 | 0.0513779 |
| RSF1 | remodeling and spacing factor 1 | 0.0465764 |
| FMNL2 | formin-like 2 | 0.0415454 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0396156 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | 0.0384384 |
| ENO1 | enolase 1, (alpha) | 0.0373847 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0366992 |
| ANGPTL4 | angiopoietin-like 4 | 0.0353656 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0314803 |
| ASPH | aspartate beta-hydroxylase | 0.0298763 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.029706 |
| HMGXB3 | HMG box domain containing 3 | 0.0283047 |
| MYO9A | myosin IXA | 0.0278447 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0276087 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0275565 |
| METTL15 | methyltransferase like 15 | 0.0275062 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0271326 |
| SLMAP | sarcolemma associated protein | 0.0267526 |
| SYNRG | synergin, gamma | 0.0267086 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0266083 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0265791 |
| IL6ST | interleukin 6 signal transducer | 0.0259268 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0249134 |
| C9ORF72 | chromosome 9 open reading frame 72 | 0.024517 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0244312 |
| PHF3 | PHD finger protein 3 | 0.0239748 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0236536 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0235037 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0234084 |
| CEP112 | centrosomal protein 112kDa | 0.0233832 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0233337 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.023316 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.023289 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0231175 |
| BAG3 | BCL2-associated athanogene 3 | 0.0231096 |
| SON | SON DNA binding protein | 0.0229737 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0227836 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0227608 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0223257 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0222384 |
| IPO8 | importin 8 | 0.0221552 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0220146 |
| FNIP1 | folliculin interacting protein 1 | 0.0218741 |
| NELFA | negative elongation factor complex member A | 0.0217285 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0216761 |
| HDAC8 | histone deacetylase 8 | 0.0215032 |
| ZNF644 | zinc finger protein 644 | 0.0213933 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | 0.0213237 |
| BLOC1S6 | biogenesis of lysosomal organelles complex-1, subunit 6, pallidin | 0.0211225 |
| RPS12 | ribosomal protein S12 | 0.0210468 |
| RPL26 | ribosomal protein L26 | 0.0209553 |
| THUMPD1 | THUMP domain containing 1 | 0.0207642 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0207314 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0207057 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0206644 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0206491 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0204661 |
| INTS6 | integrator complex subunit 6 | 0.0204576 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0204526 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0203745 |
| SPACA6 | sperm acrosome associated 6 | 0.0203398 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.020294 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.02027 |
| ITGB5 | integrin, beta 5 | 0.0202301 |
| RNF216 | ring finger protein 216 | 0.0201072 |
| MYLIP | myosin regulatory light chain interacting protein | 0.0200751 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0200482 |
| LIMA1 | LIM domain and actin binding 1 | 0.0198821 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0197922 |
| USP22 | ubiquitin specific peptidase 22 | 0.0197849 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0196622 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0195993 |
| PDE8A | phosphodiesterase 8A | 0.0195232 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0195002 |
| PAQR5 | progestin and adipoQ receptor family member V | 0.0194219 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | 0.0193879 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0193796 |
| TXNIP | thioredoxin interacting protein | 0.019374 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0192483 |
| EXOC2 | exocyst complex component 2 | 0.0191721 |
| ATXN1 | ataxin 1 | 0.0190957 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0189936 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0189498 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0187556 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0187155 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0185638 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.0184588 |
| CAPRIN2 | caprin family member 2 | 0.0184468 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0184268 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0184038 |
| GTF2I | general transcription factor IIi | 0.0183737 |
| MBTD1 | mbt domain containing 1 | 0.0183122 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 | 0.018306 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0182193 |
| TLE4 | transducin-like enhancer of split 4 | 0.0181478 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0181296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246733 |
| TMSB10 | thymosin beta 10 | -0.124135 |
| MT2A | metallothionein 2A | -0.0850572 |
| PTMA | prothymosin, alpha | -0.0825523 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0778998 |
| PKM | pyruvate kinase, muscle | -0.0749063 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0726477 |
| RPLP1 | ribosomal protein, large, P1 | -0.0679618 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0601266 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0565373 |
| ERBIN | erbb2 interacting protein | -0.0504338 |
| RTN4 | reticulon 4 | -0.0497269 |
| TMEM123 | transmembrane protein 123 | -0.0492242 |
| PHF20 | PHD finger protein 20 | -0.0464792 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0462066 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0458346 |
| S100A9 | S100 calcium binding protein A9 | -0.0458129 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0457989 |
| POTEF | POTE ankyrin domain family, member F | -0.0453934 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.045205 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.045044 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0445424 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0435258 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.043332 |
| ZNF609 | zinc finger protein 609 | -0.0429607 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0428327 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0427341 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0422203 |
| IGF2 | insulin-like growth factor 2 | -0.0417523 |
| RIGI | RNA sensor RIG-I | -0.0412002 |
| LDHA | lactate dehydrogenase A | -0.0404924 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0400201 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0395601 |
| VIM | vimentin | -0.039391 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0380767 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0368773 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0362912 |
| AHNAK | AHNAK nucleoprotein | -0.0361537 |
| VMP1 | vacuole membrane protein 1 | -0.0360906 |
| CD44 | CD44 molecule (Indian blood group) | -0.0357014 |
| DST | dystonin | -0.0346086 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0341085 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.034036 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0335465 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333809 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0330973 |
| NUP58 | nucleoporin 58 | -0.0329973 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0328397 |
| RPL35A | ribosomal protein L35a | -0.0326997 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0324811 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0319748 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0316361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.031604 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0313174 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0308765 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0303631 |
| SEPTIN7 | septin 7 | -0.030178 |
| RAD51B | RAD51 paralog B | -0.0301529 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0301023 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0300362 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0298352 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0297791 |
| BSG | basigin (Ok blood group) | -0.0296492 |
| MTDH | metadherin | -0.0296373 |
| MED13 | mediator complex subunit 13 | -0.0292706 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0292113 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0291165 |
| YBX3 | Y box binding protein 3 | -0.0289696 |
| PFN1 | profilin 1 | -0.0288895 |
| SNX14 | sorting nexin 14 | -0.0288438 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028571 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0281998 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0277641 |
| NF1 | neurofibromin 1 | -0.0275719 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0274895 |
| OSMR | oncostatin M receptor | -0.0273952 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0272331 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0271349 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0270768 |
| COG5 | component of oligomeric golgi complex 5 | -0.0269639 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0266303 |
| RPS20 | ribosomal protein S20 | -0.0263399 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0263004 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0260664 |
| FBXO11 | F-box protein 11 | -0.0258908 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0258522 |
| RPS14 | ribosomal protein S14 | -0.0258305 |
| RNF145 | ring finger protein 145 | -0.025772 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -0.0257638 |
| PREPL | prolyl endopeptidase-like | -0.0256728 |
| INSIG1 | insulin induced gene 1 | -0.0256633 |
| CCDC91 | coiled-coil domain containing 91 | -0.0254929 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0253414 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0253084 |
| ZNF207 | zinc finger protein 207 | -0.0251668 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0251457 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0249241 |
| ECT2 | epithelial cell transforming 2 | -0.0249148 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0249103 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0248498 |
