|Dataset||CTD Gene-Chemical Interactions|
|Description||A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 22.214.171.124 for the NADPH-dependent enzyme and EC 126.96.36.199 for an NADH-dependent enzyme. (Chemical Entities of Biological Interest Ontology, CHEBI_35664)|
|Downloads & Tools|
4 genes/proteins interacting with the chemical Hydroxymethylglutaryl-CoA Reductase Inhibitors from the curated CTD Gene-Chemical Interactions dataset.