| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.434969 |
| FAM13A | family with sequence similarity 13, member A | 0.0868608 |
| HELZ | helicase with zinc finger | 0.0764361 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0729092 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0705119 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0567508 |
| MEIS2 | Meis homeobox 2 | 0.0567366 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0532174 |
| PRRC2C | proline-rich coiled-coil 2C | 0.047691 |
| GOLGA4 | golgin A4 | 0.0437397 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0431493 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0426441 |
| MAP1B | microtubule-associated protein 1B | 0.0425871 |
| NUP58 | nucleoporin 58 | 0.0414878 |
| WAC | WW domain containing adaptor with coiled-coil | 0.041325 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0400477 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0386521 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0384232 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0380297 |
| WDR45B | WD repeat domain 45B | 0.0374254 |
| MYO6 | myosin VI | 0.0366526 |
| RTN4 | reticulon 4 | 0.0364678 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0359197 |
| NEK7 | NIMA-related kinase 7 | 0.0358252 |
| USP3 | ubiquitin specific peptidase 3 | 0.0339434 |
| ZNF292 | zinc finger protein 292 | 0.0333407 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0321102 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0320677 |
| XPO1 | exportin 1 | 0.0318951 |
| APP | amyloid beta (A4) precursor protein | 0.0311228 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0309552 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0307884 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0304631 |
| MEF2A | myocyte enhancer factor 2A | 0.0303571 |
| PTK2 | protein tyrosine kinase 2 | 0.0301931 |
| PAPOLA | poly(A) polymerase alpha | 0.0300957 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0295756 |
| AOPEP | aminopeptidase O (putative) | 0.0295667 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.029335 |
| DTNA | dystrobrevin, alpha | 0.0292694 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0291931 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0290176 |
| NCKAP1 | NCK-associated protein 1 | 0.0289857 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0289729 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0286178 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0284741 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.028382 |
| PKM | pyruvate kinase, muscle | 0.0283673 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283589 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0283536 |
| CLTC | clathrin, heavy chain (Hc) | 0.0279378 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0277917 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0276159 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0273073 |
| ATP13A3 | ATPase type 13A3 | 0.0268472 |
| USP34 | ubiquitin specific peptidase 34 | 0.0268356 |
| SPAG9 | sperm associated antigen 9 | 0.026832 |
| WDR43 | WD repeat domain 43 | 0.0266864 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0266387 |
| TPR | translocated promoter region, nuclear basket protein | 0.0265083 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0264207 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0262915 |
| PDS5B | PDS5 cohesin associated factor B | 0.0261837 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.026071 |
| OGA | O-GlcNAcase | 0.0257002 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0256789 |
| DPH6 | diphthamine biosynthesis 6 | 0.0251777 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0250832 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0248395 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0247905 |
| CLINT1 | clathrin interactor 1 | 0.0246339 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0245527 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0244371 |
| RLF | rearranged L-myc fusion | 0.0241554 |
| SETD5 | SET domain containing 5 | 0.0240301 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0239683 |
| TLK2 | tousled-like kinase 2 | 0.0239105 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0238988 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.023765 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0235907 |
| SRPK2 | SRSF protein kinase 2 | 0.0233881 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0232963 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.023255 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.023145 |
| NDRG1 | N-myc downstream regulated 1 | 0.0231268 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0228063 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0227999 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0227363 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0225968 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0225779 |
| YTHDC1 | YTH domain containing 1 | 0.0225632 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0225417 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0225035 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0224651 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0223253 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.022305 |
| ANGPT1 | angiopoietin 1 | 0.0222881 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0220487 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0218343 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.193162 |
| LSAMP | limbic system-associated membrane protein | -0.139026 |
| EXT1 | exostosin glycosyltransferase 1 | -0.134809 |
| NRG1 | neuregulin 1 | -0.120782 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0847331 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0745699 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.074521 |
| ACTG1 | actin gamma 1 | -0.0683656 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0625937 |
| TPM1 | tropomyosin 1 (alpha) | -0.0606135 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0554556 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0541227 |
| TLE4 | transducin-like enhancer of split 4 | -0.0537257 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0535927 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0506807 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0503601 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0498078 |
| MCL1 | myeloid cell leukemia 1 | -0.0487312 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0484484 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0483762 |
| BPTF | bromodomain PHD finger transcription factor | -0.0481703 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0479371 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.046476 |
| TRIB2 | tribbles pseudokinase 2 | -0.0463481 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0447063 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0437578 |
| COL1A1 | collagen, type I, alpha 1 | -0.0430098 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0421686 |
| MYO1E | myosin IE | -0.0418102 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0415167 |
| EGR1 | early growth response 1 | -0.0410888 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.040561 |
| PLAT | plasminogen activator, tissue | -0.0392534 |
| THBS1 | thrombospondin 1 | -0.0388074 |
| PRKCA | protein kinase C, alpha | -0.0386273 |
| NREP | neuronal regeneration related protein | -0.0385916 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0383594 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0379792 |
| RNF213 | ring finger protein 213 | -0.0372161 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0354027 |
| COL3A1 | collagen, type III, alpha 1 | -0.0352813 |
| PCBP3 | poly(rC) binding protein 3 | -0.0350973 |
| AEBP2 | AE binding protein 2 | -0.034065 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0331366 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0327089 |
| INTS6 | integrator complex subunit 6 | -0.032436 |
| SMYD3 | SET and MYND domain containing 3 | -0.0322298 |
| GSE1 | Gse1 coiled-coil protein | -0.0317754 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0313558 |
| FRMD4A | FERM domain containing 4A | -0.0312884 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.031171 |
| TMSB10 | thymosin beta 10 | -0.0307657 |
| DACH2 | dachshund family transcription factor 2 | -0.0301317 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0294085 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0290609 |
| FAM107B | family with sequence similarity 107, member B | -0.0290349 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0287822 |
| TPM4 | tropomyosin 4 | -0.0286184 |
| STK38L | serine/threonine kinase 38 like | -0.0285383 |
| ZNF804A | zinc finger protein 804A | -0.0280702 |
| CUX1 | cut-like homeobox 1 | -0.0273693 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0269705 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.026943 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0268945 |
| SIK2 | salt-inducible kinase 2 | -0.0268786 |
| GOLGB1 | golgin B1 | -0.0268761 |
| ACTN1 | actinin, alpha 1 | -0.0268318 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0264624 |
| RAD51B | RAD51 paralog B | -0.0264588 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.026431 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0257831 |
| CALD1 | caldesmon 1 | -0.025751 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0256201 |
| GLCCI1 | glucocorticoid induced 1 | -0.0255834 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0255267 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0252386 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0250902 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0248653 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0247519 |
| ACTN4 | actinin, alpha 4 | -0.0247161 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0247042 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.024672 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0243634 |
| RNF150 | ring finger protein 150 | -0.0243324 |
| CNTN4 | contactin 4 | -0.0242295 |
| CADM2 | cell adhesion molecule 2 | -0.0239689 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0238701 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0236357 |
| RPS6 | ribosomal protein S6 | -0.0235635 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0232765 |
| HDAC4 | histone deacetylase 4 | -0.0230117 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0230115 |
| VMP1 | vacuole membrane protein 1 | -0.0227404 |
| GPC6 | glypican 6 | -0.0225633 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0223128 |
| HOMER1 | homer scaffolding protein 1 | -0.0222413 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0221938 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0221515 |
| PRKCE | protein kinase C, epsilon | -0.0221141 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0220423 |
