| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0999196 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0952344 |
| INTS6 | integrator complex subunit 6 | 0.0937804 |
| VCL | vinculin | 0.084334 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0813667 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0659137 |
| SMAD3 | SMAD family member 3 | 0.0649928 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0587448 |
| ATXN1 | ataxin 1 | 0.058056 |
| TXNIP | thioredoxin interacting protein | 0.0576237 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0533497 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0518209 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0501853 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0492541 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0484114 |
| PLSCR2 | phospholipid scramblase 2 | 0.0480965 |
| RAD51B | RAD51 paralog B | 0.0478899 |
| ZNF292 | zinc finger protein 292 | 0.045953 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0452904 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0450241 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0444437 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0415637 |
| VMP1 | vacuole membrane protein 1 | 0.039883 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0398348 |
| ANXA2 | annexin A2 | 0.0397729 |
| RNF43 | ring finger protein 43 | 0.0386196 |
| FNIP1 | folliculin interacting protein 1 | 0.0378574 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0376601 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0374121 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0360858 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0352824 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0350652 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0349334 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0346795 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0340597 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0339473 |
| YAP1 | Yes-associated protein 1 | 0.0338952 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0334384 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0332919 |
| PRELID2 | PRELI domain containing 2 | 0.0332564 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0321299 |
| IFNGR1 | interferon gamma receptor 1 | 0.0317799 |
| PTEN | phosphatase and tensin homolog | 0.0316977 |
| MAP7 | microtubule-associated protein 7 | 0.0303923 |
| EFNB2 | ephrin-B2 | 0.0303045 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0298822 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0296727 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0293528 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0293084 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0292859 |
| ASPH | aspartate beta-hydroxylase | 0.0290331 |
| RUNX1 | runt-related transcription factor 1 | 0.0288818 |
| PRKCA | protein kinase C, alpha | 0.0287287 |
| EREG | epiregulin | 0.0282857 |
| SBF2 | SET binding factor 2 | 0.0281521 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0281052 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0275739 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0274146 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.02739 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0268327 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0268318 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0266872 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0265944 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0256382 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0254822 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0249215 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0249167 |
| EXOC4 | exocyst complex component 4 | 0.0249083 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0247056 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0246136 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0243681 |
| RPS6 | ribosomal protein S6 | 0.0241711 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0241395 |
| FOXP1 | forkhead box P1 | 0.0236165 |
| DIAPH3 | diaphanous-related formin 3 | 0.0235136 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0233102 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0232896 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0232303 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0231253 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0230615 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0228736 |
| WWOX | WW domain containing oxidoreductase | 0.0228702 |
| MED13L | mediator complex subunit 13-like | 0.0225908 |
| AHI1 | Abelson helper integration site 1 | 0.0224271 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0223647 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0222581 |
| UBAC2 | UBA domain containing 2 | 0.0221988 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0221175 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0220926 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0220763 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0220028 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0218662 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217984 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0217282 |
| METTL15 | methyltransferase like 15 | 0.0216088 |
| TUFT1 | tuftelin 1 | 0.0215996 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0211175 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0210737 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0206007 |
| FRK | fyn-related Src family tyrosine kinase | 0.0205672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.130876 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.102993 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0987198 |
| HLA-B | major histocompatibility complex, class I, B | -0.091193 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0899945 |
| LYZ | lysozyme | -0.0836958 |
| SQSTM1 | sequestosome 1 | -0.080507 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0745268 |
| PTMA | prothymosin, alpha | -0.0725308 |
| HLA-E | major histocompatibility complex, class I, E | -0.0631306 |
| JUN | jun proto-oncogene | -0.0616853 |
| LMO7 | LIM domain 7 | -0.0591774 |
| EZR | ezrin | -0.0540929 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0539778 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0531036 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0519943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0516978 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0508202 |
| EGR1 | early growth response 1 | -0.0506455 |
| H1-0 | H1.0 linker histone | -0.0491466 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0489003 |
| ITGA6 | integrin, alpha 6 | -0.0484075 |
| MX2 | MX dynamin-like GTPase 2 | -0.0476855 |
| LCN2 | lipocalin 2 | -0.0472114 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0471307 |
| RRBP1 | ribosome binding protein 1 | -0.0463314 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0455895 |
| RIGI | RNA sensor RIG-I | -0.0448061 |
| SPATA13 | spermatogenesis associated 13 | -0.0434297 |
| PERP | PERP, TP53 apoptosis effector | -0.0426749 |
| CANX | calnexin | -0.0426234 |
| TMC5 | transmembrane channel-like 5 | -0.0424959 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0414114 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0413552 |
| NCOA7 | nuclear receptor coactivator 7 | -0.040896 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0407823 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0404908 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0383919 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0380025 |
| TMSB10 | thymosin beta 10 | -0.037725 |
| WDR45B | WD repeat domain 45B | -0.0364165 |
| XAF1 | XIAP associated factor 1 | -0.0364073 |
| MUC20 | mucin 20, cell surface associated | -0.0362823 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0360053 |
| FTL | ferritin, light polypeptide | -0.0357993 |
| EPHB2 | EPH receptor B2 | -0.0356746 |
| EPCAM | epithelial cell adhesion molecule | -0.0356638 |
| S100A6 | S100 calcium binding protein A6 | -0.0346265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0345837 |
| MUC13 | mucin 13, cell surface associated | -0.0337072 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.033496 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0328539 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0325456 |
| HLA-A | major histocompatibility complex, class I, A | -0.0317769 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0315557 |
| MX1 | MX dynamin-like GTPase 1 | -0.0314243 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0310366 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0309514 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0308993 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0306316 |
| ATF4 | activating transcription factor 4 | -0.0304302 |
| RPL35A | ribosomal protein L35a | -0.0303943 |
| ACTG1 | actin gamma 1 | -0.0302798 |
| TFRC | transferrin receptor | -0.0291951 |
| ABLIM1 | actin binding LIM protein 1 | -0.0286279 |
| MT2A | metallothionein 2A | -0.0279236 |
| APOL1 | apolipoprotein L, 1 | -0.0278789 |
| UBC | ubiquitin C | -0.0276483 |
| HLA-C | major histocompatibility complex, class I, C | -0.0272864 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.026757 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267245 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0266781 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0260231 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0257471 |
| IRF1 | interferon regulatory factor 1 | -0.0255236 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0253859 |
| CDHR2 | cadherin-related family member 2 | -0.0247367 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0244003 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0243882 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0243107 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0238828 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.023733 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.023641 |
| CSTB | cystatin B (stefin B) | -0.0234777 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0231345 |
| AHNAK | AHNAK nucleoprotein | -0.0230711 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0230019 |
| ANXA4 | annexin A4 | -0.0227363 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0227036 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0227036 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0225155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0224112 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0223905 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0219982 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219264 |
| IER2 | immediate early response 2 | -0.0219105 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0218448 |
| PGK1 | phosphoglycerate kinase 1 | -0.0216014 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.021326 |
| SSH2 | slingshot protein phosphatase 2 | -0.0211526 |
