| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.168316 |
| MTSS1 | metastasis suppressor 1 | 0.165941 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.12091 |
| FLNB | filamin B, beta | 0.108498 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.103512 |
| MYOF | myoferlin | 0.101343 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0929837 |
| NDRG1 | N-myc downstream regulated 1 | 0.0912224 |
| KIAA1217 | KIAA1217 | 0.0853407 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0732067 |
| RIN2 | Ras and Rab interactor 2 | 0.0717596 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0711358 |
| PODXL | podocalyxin-like | 0.0646773 |
| NAV2 | neuron navigator 2 | 0.0618282 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0612164 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0595987 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0567255 |
| ZNF292 | zinc finger protein 292 | 0.0560145 |
| PRELID2 | PRELI domain containing 2 | 0.0557968 |
| ITGA6 | integrin, alpha 6 | 0.0539912 |
| ANLN | anillin, actin binding protein | 0.0527711 |
| PTK2 | protein tyrosine kinase 2 | 0.0526509 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0503145 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0502449 |
| ENO1 | enolase 1, (alpha) | 0.0502206 |
| MYO10 | myosin X | 0.0499489 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0491982 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0484785 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0466556 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0462433 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0455571 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0445902 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0445809 |
| KRT6A | keratin 6A, type II | 0.0439475 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422359 |
| GRB10 | growth factor receptor-bound protein 10 | 0.042197 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0419392 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.041917 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0417834 |
| SBF2 | SET binding factor 2 | 0.0414251 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0413367 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0402658 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0398643 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0380606 |
| ANXA2 | annexin A2 | 0.0379503 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0375539 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0368697 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0367572 |
| EZR | ezrin | 0.0367554 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0361696 |
| EMP1 | epithelial membrane protein 1 | 0.0360221 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359624 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0359194 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0356314 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.03559 |
| AFAP1 | actin filament associated protein 1 | 0.0353044 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0352817 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0348092 |
| GATA6 | GATA binding protein 6 | 0.0343998 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0337824 |
| COG5 | component of oligomeric golgi complex 5 | 0.0337139 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0331417 |
| USP3 | ubiquitin specific peptidase 3 | 0.0330991 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0323377 |
| NBAS | neuroblastoma amplified sequence | 0.0322776 |
| GOLGA4 | golgin A4 | 0.0319604 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0319085 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0317785 |
| SULF1 | sulfatase 1 | 0.0313223 |
| DOK5 | docking protein 5 | 0.0311058 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0311008 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0310368 |
| NUP58 | nucleoporin 58 | 0.0308834 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0306822 |
| MATR3 | matrin 3 | 0.0305781 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0297474 |
| SPAG9 | sperm associated antigen 9 | 0.029504 |
| MXI1 | MAX interactor 1, dimerization protein | 0.02908 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0284891 |
| ANXA5 | annexin A5 | 0.0278263 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0277645 |
| TOP1 | topoisomerase (DNA) I | 0.0275907 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275308 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0271903 |
| OGA | O-GlcNAcase | 0.0271743 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0269933 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02698 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0269383 |
| TMEM123 | transmembrane protein 123 | 0.026865 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0267408 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0266506 |
| ARRDC3 | arrestin domain containing 3 | 0.0265991 |
| DSTN | destrin (actin depolymerizing factor) | 0.0265952 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0265831 |
| XPO1 | exportin 1 | 0.0264945 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0264833 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.026434 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.026315 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0261115 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0258207 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDLIM5 | PDZ and LIM domain 5 | -0.11947 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0867608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0794862 |
| VCL | vinculin | -0.0765614 |
| TMSB10 | thymosin beta 10 | -0.0722209 |
| INTS6 | integrator complex subunit 6 | -0.0715796 |
| EGR1 | early growth response 1 | -0.0542897 |
| LMO7 | LIM domain 7 | -0.0542136 |
| MT2A | metallothionein 2A | -0.049058 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0457894 |
| PTMA | prothymosin, alpha | -0.0420552 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0418072 |
| RPLP2 | ribosomal protein, large, P2 | -0.041614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403575 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0396066 |
| FAM107B | family with sequence similarity 107, member B | -0.0383448 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0374121 |
| FTL | ferritin, light polypeptide | -0.0365187 |
| HLA-B | major histocompatibility complex, class I, B | -0.035958 |
| SETX | senataxin | -0.0354602 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348124 |
| SEPTIN9 | septin 9 | -0.0328253 |
| DUSP6 | dual specificity phosphatase 6 | -0.0327286 |
| RCOR1 | REST corepressor 1 | -0.0326389 |
| PALLD | palladin, cytoskeletal associated protein | -0.0325601 |
| DIAPH1 | diaphanous-related formin 1 | -0.0325461 |
| RPS25 | ribosomal protein S25 | -0.032132 |
| RPS3 | ribosomal protein S3 | -0.0315071 |
| FN1 | fibronectin 1 | -0.0314802 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0313752 |
| RPL12 | ribosomal protein L12 | -0.0311028 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0310154 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0303641 |
| DHFR | dihydrofolate reductase | -0.0301786 |
| RPS8 | ribosomal protein S8 | -0.0301017 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0290566 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0288861 |
| FOXO1 | forkhead box O1 | -0.0283364 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0274124 |
| RPS6 | ribosomal protein S6 | -0.0272826 |
| MT1X | metallothionein 1X | -0.0272653 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0268406 |
| COPA | coatomer protein complex, subunit alpha | -0.0268353 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0264035 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0263386 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0261435 |
| RPL36A | ribosomal protein L36a | -0.0259962 |
| B2M | beta-2-microglobulin | -0.0255123 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0249231 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0247614 |
| CORO2A | coronin, actin binding protein, 2A | -0.0240664 |
| WASF2 | WAS protein family, member 2 | -0.0238348 |
| RPL11 | ribosomal protein L11 | -0.0234369 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0232797 |
| JMJD1C | jumonji domain containing 1C | -0.0232118 |
| RPL35A | ribosomal protein L35a | -0.023105 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0230918 |
| LUZP1 | leucine zipper protein 1 | -0.0230868 |
| GPR176 | G protein-coupled receptor 176 | -0.0230059 |
| EGFR | epidermal growth factor receptor | -0.0229788 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0229658 |
| LAMA5 | laminin, alpha 5 | -0.0229094 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0227848 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0227132 |
| RPS21 | ribosomal protein S21 | -0.0223585 |
| GOLGB1 | golgin B1 | -0.0218955 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0218419 |
| RPS16 | ribosomal protein S16 | -0.0217968 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0217121 |
| CD9 | CD9 molecule | -0.0211014 |
| RPL8 | ribosomal protein L8 | -0.021009 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0209637 |
| S100A10 | S100 calcium binding protein A10 | -0.0208023 |
| SIK3 | SIK family kinase 3 | -0.0207517 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0207023 |
| IGF2 | insulin-like growth factor 2 | -0.0205874 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.020313 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0202955 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0200151 |
| ACTN1 | actinin, alpha 1 | -0.0199415 |
| SVIL | supervillin | -0.0198452 |
| RPS13 | ribosomal protein S13 | -0.0196477 |
| AMOTL1 | angiomotin like 1 | -0.0196251 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.019608 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0194471 |
| MEIS2 | Meis homeobox 2 | -0.0191163 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0190225 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0189823 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.018918 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0189041 |
| SQLE | squalene epoxidase | -0.0187488 |
| RPS19 | ribosomal protein S19 | -0.0187322 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0186895 |
| RPS27 | ribosomal protein S27 | -0.0186647 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0186451 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0185317 |
| ATF4 | activating transcription factor 4 | -0.018453 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0184508 |
| CTBP2 | C-terminal binding protein 2 | -0.0183169 |
| SQSTM1 | sequestosome 1 | -0.0182371 |
