| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EREG | epiregulin | 0.110524 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.102597 |
| RPS12 | ribosomal protein S12 | 0.0995352 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.096444 |
| ONECUT3 | one cut homeobox 3 | 0.074059 |
| MED13L | mediator complex subunit 13-like | 0.0672955 |
| S100P | S100 calcium binding protein P | 0.0669144 |
| AREG | amphiregulin | 0.0617956 |
| RPS8 | ribosomal protein S8 | 0.0616408 |
| RPL26 | ribosomal protein L26 | 0.0607905 |
| FLNB | filamin B, beta | 0.0598108 |
| FAM13A | family with sequence similarity 13, member A | 0.0574379 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.057084 |
| RPL5 | ribosomal protein L5 | 0.0547983 |
| RPL13A | ribosomal protein L13a | 0.0540104 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0535079 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0533901 |
| SPAG9 | sperm associated antigen 9 | 0.0524211 |
| RPL37A | ribosomal protein L37a | 0.0522279 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0505111 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0499253 |
| RPS23 | ribosomal protein S23 | 0.0467471 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0466589 |
| RPLP2 | ribosomal protein, large, P2 | 0.0459619 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0458406 |
| GOLGA4 | golgin A4 | 0.0457138 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.045713 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0451083 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0446491 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0445955 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0442457 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.044227 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0440148 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0439691 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0439502 |
| COG5 | component of oligomeric golgi complex 5 | 0.0437633 |
| RBM39 | RNA binding motif protein 39 | 0.0436418 |
| RNF145 | ring finger protein 145 | 0.0436151 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0429378 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0429348 |
| RPS3 | ribosomal protein S3 | 0.0428832 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0427062 |
| B2M | beta-2-microglobulin | 0.042533 |
| RPL36 | ribosomal protein L36 | 0.0423061 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.041568 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0414089 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0410962 |
| RPS29 | ribosomal protein S29 | 0.0409668 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0408854 |
| PRELID2 | PRELI domain containing 2 | 0.0406736 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0405469 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0403424 |
| MXD1 | MAX dimerization protein 1 | 0.0402354 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0400399 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0387511 |
| OGA | O-GlcNAcase | 0.0386544 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0375666 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0374594 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0363456 |
| HMGA1 | high mobility group AT-hook 1 | 0.036182 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.035578 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0349851 |
| RPS17 | ribosomal protein S17 | 0.0349418 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0342095 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0339876 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0339582 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0338884 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0338562 |
| RPS2 | ribosomal protein S2 | 0.0338273 |
| FOXO1 | forkhead box O1 | 0.0335519 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0335346 |
| SLMAP | sarcolemma associated protein | 0.0332835 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.033109 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0329601 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0326734 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0325507 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0320139 |
| RPS25 | ribosomal protein S25 | 0.0319435 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0319331 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0317294 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0316245 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0315671 |
| RREB1 | ras responsive element binding protein 1 | 0.031553 |
| ZNF292 | zinc finger protein 292 | 0.0314481 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0311223 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0310942 |
| NBAS | neuroblastoma amplified sequence | 0.0306169 |
| VEGFA | vascular endothelial growth factor A | 0.0300575 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0297231 |
| RPL31 | ribosomal protein L31 | 0.0296484 |
| SSR1 | signal sequence receptor, alpha | 0.029111 |
| PARD3 | par-3 family cell polarity regulator | 0.0290874 |
| BBX | bobby sox homolog (Drosophila) | 0.0290661 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.028522 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0283117 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280671 |
| NCOR1 | nuclear receptor corepressor 1 | 0.028061 |
| LMO7 | LIM domain 7 | 0.0278413 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0276099 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0275618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.222854 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180885 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.113126 |
| EZR | ezrin | -0.104969 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0958614 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0928028 |
| KRT18 | keratin 18, type I | -0.0878698 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0824497 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0752343 |
| DSPP | dentin sialophosphoprotein | -0.0696579 |
| AHNAK | AHNAK nucleoprotein | -0.063488 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0621482 |
| PTMA | prothymosin, alpha | -0.0609879 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0590566 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.057535 |
| TMSB10 | thymosin beta 10 | -0.0551025 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0544188 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0513558 |
| MLEC | malectin | -0.0499182 |
| CANX | calnexin | -0.049873 |
| LDHA | lactate dehydrogenase A | -0.0486492 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.048047 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0476101 |
| ITGA6 | integrin, alpha 6 | -0.046908 |
| TPM4 | tropomyosin 4 | -0.0466604 |
| POTEF | POTE ankyrin domain family, member F | -0.0451708 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0443726 |
| PGK1 | phosphoglycerate kinase 1 | -0.0440359 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0434847 |
| RPS19 | ribosomal protein S19 | -0.0420164 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0411058 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0402602 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0390007 |
| H1-0 | H1.0 linker histone | -0.0377839 |
| RPL35A | ribosomal protein L35a | -0.0377211 |
| MUC17 | mucin 17, cell surface associated | -0.0375672 |
| KRT19 | keratin 19, type I | -0.0375026 |
| S100A6 | S100 calcium binding protein A6 | -0.0374225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0373977 |
| YBX1 | Y box binding protein 1 | -0.0370519 |
| NPSR1 | neuropeptide S receptor 1 | -0.0366279 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0365775 |
| TXNIP | thioredoxin interacting protein | -0.0364954 |
| EPCAM | epithelial cell adhesion molecule | -0.0360025 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0358263 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0357647 |
| ACTG1 | actin gamma 1 | -0.0327326 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0322113 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0316966 |
| JUN | jun proto-oncogene | -0.0315756 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0314053 |
| PIGR | polymeric immunoglobulin receptor | -0.0308745 |
| EGR1 | early growth response 1 | -0.0306645 |
| PERP | PERP, TP53 apoptosis effector | -0.0306193 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0304034 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0301656 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0300899 |
| INSIG1 | insulin induced gene 1 | -0.0288992 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0287313 |
| CENPF | centromere protein F, 350/400kDa | -0.0284902 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0279727 |
| CLDN7 | claudin 7 | -0.027849 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0273254 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267325 |
| MT1X | metallothionein 1X | -0.0266102 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0263627 |
| GPHN | gephyrin | -0.0257834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0238992 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0237322 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0236445 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0235855 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0229765 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.022892 |
| ANXA1 | annexin A1 | -0.0228012 |
| ENO1 | enolase 1, (alpha) | -0.0226532 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0223773 |
| RPS14 | ribosomal protein S14 | -0.0221911 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.022185 |
| PCM1 | pericentriolar material 1 | -0.0217871 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0217862 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0216491 |
| AGR2 | anterior gradient 2 | -0.0216221 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0214169 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0213534 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0211643 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0209644 |
| RPL21 | ribosomal protein L21 | -0.0206413 |
| DSTN | destrin (actin depolymerizing factor) | -0.0205816 |
| CDK6 | cyclin-dependent kinase 6 | -0.0205098 |
| KRT8 | keratin 8, type II | -0.0200337 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0199599 |
| LDHB | lactate dehydrogenase B | -0.0194056 |
| LYZ | lysozyme | -0.0193554 |
| DEK | DEK proto-oncogene | -0.018915 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0186612 |
| NRN1 | neuritin 1 | -0.0185069 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0183035 |
| TUBA1B | tubulin, alpha 1b | -0.0181984 |
| EMP1 | epithelial membrane protein 1 | -0.018174 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0175903 |
