| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.109856 |
| RAD51B | RAD51 paralog B | 0.109088 |
| TXNRD1 | thioredoxin reductase 1 | 0.0922078 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0876727 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0583949 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0575723 |
| RPL5 | ribosomal protein L5 | 0.0538819 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0536669 |
| ZNF292 | zinc finger protein 292 | 0.0517584 |
| ANXA5 | annexin A5 | 0.0488716 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0480958 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0469767 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0465889 |
| EXOC4 | exocyst complex component 4 | 0.0464785 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0447381 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0427714 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0426763 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0424942 |
| BBX | bobby sox homolog (Drosophila) | 0.0423317 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0422994 |
| TMEM165 | transmembrane protein 165 | 0.041546 |
| MED13L | mediator complex subunit 13-like | 0.0409188 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0406046 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0388884 |
| WDR43 | WD repeat domain 43 | 0.0387777 |
| HMGA1 | high mobility group AT-hook 1 | 0.0384368 |
| TNPO3 | transportin 3 | 0.0373237 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0373148 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0360571 |
| VMP1 | vacuole membrane protein 1 | 0.0358548 |
| ATP13A3 | ATPase type 13A3 | 0.0357539 |
| PARD3 | par-3 family cell polarity regulator | 0.0354052 |
| SMAD3 | SMAD family member 3 | 0.0352186 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0350556 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0349018 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0340975 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0331332 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.032921 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0327592 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0327336 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0322633 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0322553 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0319461 |
| PTEN | phosphatase and tensin homolog | 0.0309264 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0307885 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0302326 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0302003 |
| TBK1 | TANK-binding kinase 1 | 0.030044 |
| RBM25 | RNA binding motif protein 25 | 0.0294171 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0293654 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0291583 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0290169 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0286064 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.028456 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0280319 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0277881 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0275107 |
| PCBP2 | poly(rC) binding protein 2 | 0.0274362 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0271636 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0266307 |
| RTN4 | reticulon 4 | 0.0265697 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0265693 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0264397 |
| PHF21A | PHD finger protein 21A | 0.0262351 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0260797 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0260332 |
| COG5 | component of oligomeric golgi complex 5 | 0.0259465 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0258117 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0257399 |
| NCKAP1 | NCK-associated protein 1 | 0.0256614 |
| SRPK2 | SRSF protein kinase 2 | 0.0256489 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.0255967 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0253085 |
| WWOX | WW domain containing oxidoreductase | 0.0251914 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0251469 |
| PTK2 | protein tyrosine kinase 2 | 0.0251345 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0250738 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0250673 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0247481 |
| KIAA1328 | KIAA1328 | 0.0247328 |
| EGFR | epidermal growth factor receptor | 0.0247156 |
| CDYL | chromodomain protein, Y-like | 0.0246616 |
| PHIP | pleckstrin homology domain interacting protein | 0.0245785 |
| NF1 | neurofibromin 1 | 0.0245685 |
| XPOT | exportin, tRNA | 0.0245494 |
| FAM168A | family with sequence similarity 168, member A | 0.024466 |
| HMGA2 | high mobility group AT-hook 2 | 0.0244063 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0243026 |
| NUP58 | nucleoporin 58 | 0.0242783 |
| FMNL2 | formin-like 2 | 0.0242768 |
| SNX9 | sorting nexin 9 | 0.0242205 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0239304 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0237515 |
| RNF38 | ring finger protein 38 | 0.0237489 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0236526 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0236213 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0236154 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0235743 |
| GRAMD1B | GRAM domain containing 1B | 0.0231903 |
| RFX7 | regulatory factor X, 7 | 0.0231815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.282201 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.148288 |
| YBX3 | Y box binding protein 3 | -0.129882 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123661 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0998435 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0892942 |
| CANX | calnexin | -0.082681 |
| TMSB10 | thymosin beta 10 | -0.0810101 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0778669 |
| ACTG1 | actin gamma 1 | -0.063834 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0587065 |
| MCL1 | myeloid cell leukemia 1 | -0.0557891 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.05545 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0492038 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0481651 |
| GOLGB1 | golgin B1 | -0.0479046 |
| AHNAK | AHNAK nucleoprotein | -0.0476475 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0459123 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0458446 |
| BRD2 | bromodomain containing 2 | -0.0434575 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0433406 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0432875 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0416166 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0410114 |
| KRT18 | keratin 18, type I | -0.0401481 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0389796 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0374573 |
| HLA-B | major histocompatibility complex, class I, B | -0.0372066 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0355547 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0345268 |
| INTS6 | integrator complex subunit 6 | -0.0344385 |
| H1-0 | H1.0 linker histone | -0.0344004 |
| CLTC | clathrin, heavy chain (Hc) | -0.0338215 |
| RPS2 | ribosomal protein S2 | -0.0337747 |
| LRRC23 | leucine rich repeat containing 23 | -0.0332853 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0328606 |
| RPS19 | ribosomal protein S19 | -0.0321086 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320384 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0313374 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0304986 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0302784 |
| CAVIN1 | caveolae associated protein 1 | -0.0295649 |
| PTMA | prothymosin, alpha | -0.0294208 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0293959 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0288151 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0288102 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0280517 |
| UBB | ubiquitin B | -0.0277763 |
| SET | SET nuclear proto-oncogene | -0.0275604 |
| YBX1 | Y box binding protein 1 | -0.0269971 |
| DSPP | dentin sialophosphoprotein | -0.0253128 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0249938 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0248659 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.024712 |
| UBC | ubiquitin C | -0.0246979 |
| SETX | senataxin | -0.0246259 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0244603 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0241956 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0239412 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0239106 |
| KIF5B | kinesin family member 5B | -0.0237903 |
| RPL3 | ribosomal protein L3 | -0.0237815 |
| RPS27A | ribosomal protein S27a | -0.0236535 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0235452 |
| TPM2 | tropomyosin 2 (beta) | -0.0234253 |
| EGR1 | early growth response 1 | -0.0230299 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.023015 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0228779 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0228368 |
| CDK12 | cyclin-dependent kinase 12 | -0.0225148 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0223517 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0223281 |
| FTL | ferritin, light polypeptide | -0.0221697 |
| VCL | vinculin | -0.0218494 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0216601 |
| B2M | beta-2-microglobulin | -0.0214999 |
| CALR | calreticulin | -0.0214471 |
| STK4 | serine/threonine kinase 4 | -0.0213528 |
| CUL4B | cullin 4B | -0.0210558 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0209875 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0209633 |
| PLEC | plectin | -0.0207325 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0207287 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0206344 |
| MKI67 | marker of proliferation Ki-67 | -0.0205322 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0203597 |
| IER3 | immediate early response 3 | -0.0203171 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0202639 |
| TPM4 | tropomyosin 4 | -0.020165 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0200866 |
| SEC61G | Sec61 gamma subunit | -0.0199962 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0198296 |
| WBP11 | WW domain binding protein 11 | -0.0195567 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0194282 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0193607 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0193341 |
| RPL38 | ribosomal protein L38 | -0.0193055 |
| GON4L | gon-4-like (C. elegans) | -0.0191605 |
| ARF1 | ADP-ribosylation factor 1 | -0.0190985 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0189048 |
