| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0745753 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0711798 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0640018 |
| RPS6 | ribosomal protein S6 | 0.0627908 |
| ZNF292 | zinc finger protein 292 | 0.0594146 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.053834 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0525198 |
| ATP13A3 | ATPase type 13A3 | 0.0461211 |
| HMGA1 | high mobility group AT-hook 1 | 0.0385707 |
| MT2A | metallothionein 2A | 0.0384317 |
| VEGFA | vascular endothelial growth factor A | 0.0357188 |
| SBF2 | SET binding factor 2 | 0.0355124 |
| RPS3 | ribosomal protein S3 | 0.0353797 |
| RPL5 | ribosomal protein L5 | 0.0349372 |
| RPS12 | ribosomal protein S12 | 0.0348318 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0341042 |
| MKI67 | marker of proliferation Ki-67 | 0.0322021 |
| NAV2 | neuron navigator 2 | 0.0320719 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0309842 |
| ARRDC3 | arrestin domain containing 3 | 0.0308393 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0301607 |
| ANLN | anillin, actin binding protein | 0.0289572 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0288191 |
| SPAG9 | sperm associated antigen 9 | 0.028713 |
| DIAPH3 | diaphanous-related formin 3 | 0.0277284 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0277209 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0275504 |
| RPL9 | ribosomal protein L9 | 0.0274082 |
| ANXA5 | annexin A5 | 0.0268529 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.026307 |
| CCNL1 | cyclin L1 | 0.0258177 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0257904 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0254768 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0248445 |
| RTN4 | reticulon 4 | 0.024832 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0246368 |
| JMJD1C | jumonji domain containing 1C | 0.0241728 |
| RPL36 | ribosomal protein L36 | 0.0240088 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0237706 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0236771 |
| RACK1 | receptor for activated C kinase 1 | 0.0233822 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.022916 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0226598 |
| SMC4 | structural maintenance of chromosomes 4 | 0.022593 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0225874 |
| KIF4A | kinesin family member 4A | 0.0225861 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0223885 |
| FOSL1 | FOS-like antigen 1 | 0.0223593 |
| RNF145 | ring finger protein 145 | 0.0221867 |
| RPS8 | ribosomal protein S8 | 0.0216088 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0213501 |
| RPS23 | ribosomal protein S23 | 0.0213269 |
| HELZ | helicase with zinc finger | 0.021183 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0209004 |
| TPX2 | TPX2, microtubule-associated | 0.0201031 |
| KLF6 | Kruppel-like factor 6 | 0.0200774 |
| RPL7A | ribosomal protein L7a | 0.0197173 |
| RPLP2 | ribosomal protein, large, P2 | 0.0192595 |
| RNF24 | ring finger protein 24 | 0.0189753 |
| RPS21 | ribosomal protein S21 | 0.0188621 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0188304 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0186629 |
| RPL37A | ribosomal protein L37a | 0.0185802 |
| MIS18BP1 | MIS18 binding protein 1 | 0.018511 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0183288 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0182013 |
| MSN | moesin | 0.0180872 |
| DENND4C | DENN/MADD domain containing 4C | 0.0180738 |
| PFN1 | profilin 1 | 0.0180359 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0178997 |
| TBK1 | TANK-binding kinase 1 | 0.017881 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0175246 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0174911 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0172611 |
| SNX13 | sorting nexin 13 | 0.0171871 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.016847 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0168423 |
| WTAP | Wilms tumor 1 associated protein | 0.0168334 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.016814 |
| RPS29 | ribosomal protein S29 | 0.0167539 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0167217 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0166549 |
| CDC27 | cell division cycle 27 | 0.0166032 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0165193 |
| SRGN | serglycin | 0.0163575 |
| KIF13A | kinesin family member 13A | 0.0163089 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0162876 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0161097 |
| PHIP | pleckstrin homology domain interacting protein | 0.0160504 |
| TTK | TTK protein kinase | 0.0160404 |
| RASA2 | RAS p21 protein activator 2 | 0.0160075 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.015941 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0159188 |
| TGFB2 | transforming growth factor, beta 2 | 0.0157556 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0156671 |
| CENPF | centromere protein F, 350/400kDa | 0.0155157 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.015459 |
| NUP58 | nucleoporin 58 | 0.0154265 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0152634 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0152136 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.247228 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.211938 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.18157 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.166161 |
| AHNAK | AHNAK nucleoprotein | -0.124587 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.122947 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.118361 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.114072 |
| CANX | calnexin | -0.110315 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.108861 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.104767 |
| IER3 | immediate early response 3 | -0.0984459 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0933503 |
| GLIS3 | GLIS family zinc finger 3 | -0.0895225 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0872439 |
| ENO1 | enolase 1, (alpha) | -0.0821917 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0816633 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0811586 |
| CD44 | CD44 molecule (Indian blood group) | -0.0806774 |
| LDHA | lactate dehydrogenase A | -0.0792181 |
| UBC | ubiquitin C | -0.0766015 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0765167 |
| DST | dystonin | -0.0738782 |
| HMGA2 | high mobility group AT-hook 2 | -0.0736843 |
| HLA-E | major histocompatibility complex, class I, E | -0.0714659 |
| CALR | calreticulin | -0.0691737 |
| TMSB10 | thymosin beta 10 | -0.0665019 |
| CDH13 | cadherin 13 | -0.0660287 |
| PLIN2 | perilipin 2 | -0.0646194 |
| PGK1 | phosphoglycerate kinase 1 | -0.0639188 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0599613 |
| VCL | vinculin | -0.0593746 |
| ASPH | aspartate beta-hydroxylase | -0.0582162 |
| SQSTM1 | sequestosome 1 | -0.0580623 |
| TMSB4X | thymosin beta 4, X-linked | -0.0576007 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0568192 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0568113 |
| VCAN | versican | -0.0552832 |
| PHF3 | PHD finger protein 3 | -0.0549815 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0548915 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0543171 |
| HLA-B | major histocompatibility complex, class I, B | -0.0526409 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0523077 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0509739 |
| GOLGB1 | golgin B1 | -0.0499222 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0449763 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0447089 |
| RND3 | Rho family GTPase 3 | -0.0444833 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.044113 |
| CTSB | cathepsin B | -0.0433393 |
| FN1 | fibronectin 1 | -0.0417906 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0413577 |
| INTS6 | integrator complex subunit 6 | -0.0412483 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.040778 |
| RAI14 | retinoic acid induced 14 | -0.0400349 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0400152 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.038347 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0375333 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0370377 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0368459 |
| HLA-A | major histocompatibility complex, class I, A | -0.0367947 |
| COL1A1 | collagen, type I, alpha 1 | -0.0359822 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0357041 |
| FAM20C | family with sequence similarity 20, member C | -0.0354546 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0348099 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0343708 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0342432 |
| NAV1 | neuron navigator 1 | -0.0340932 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0338255 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0335822 |
| JUN | jun proto-oncogene | -0.0335732 |
| DIAPH2 | diaphanous-related formin 2 | -0.0333372 |
| SP100 | SP100 nuclear antigen | -0.0330741 |
| FTL | ferritin, light polypeptide | -0.0329981 |
| HDAC9 | histone deacetylase 9 | -0.0329784 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0329512 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0324059 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0323864 |
| RRBP1 | ribosome binding protein 1 | -0.0323442 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0321906 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0320713 |
| BICC1 | BicC family RNA binding protein 1 | -0.03172 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0313142 |
| HDLBP | high density lipoprotein binding protein | -0.0310692 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0308496 |
| FRMD4A | FERM domain containing 4A | -0.0300915 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0298873 |
| TPM4 | tropomyosin 4 | -0.0294198 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0293965 |
| STC1 | stanniocalcin 1 | -0.0293834 |
| COL5A1 | collagen, type V, alpha 1 | -0.0293434 |
| CUL4B | cullin 4B | -0.02913 |
| TMEM132D | transmembrane protein 132D | -0.0289977 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0287517 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0287145 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0284455 |
| APP | amyloid beta (A4) precursor protein | -0.0279445 |
| TAOK1 | TAO kinase 1 | -0.027584 |
| NRN1 | neuritin 1 | -0.0273977 |
| GPC6 | glypican 6 | -0.0273598 |
