| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.129733 |
| ENO1 | enolase 1, (alpha) | 0.0937852 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0749499 |
| VMP1 | vacuole membrane protein 1 | 0.0683824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0637554 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.063472 |
| SBF2 | SET binding factor 2 | 0.0622768 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0609353 |
| GOLGA4 | golgin A4 | 0.0596863 |
| LDHA | lactate dehydrogenase A | 0.059549 |
| MORF4L2 | mortality factor 4 like 2 | 0.0585018 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0582799 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0578687 |
| FMNL2 | formin-like 2 | 0.0574394 |
| MKI67 | marker of proliferation Ki-67 | 0.0570479 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0561641 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0557568 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0531919 |
| BBX | bobby sox homolog (Drosophila) | 0.0520932 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0517062 |
| ANLN | anillin, actin binding protein | 0.0509308 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0505584 |
| S100A9 | S100 calcium binding protein A9 | 0.0496152 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.04918 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0489264 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0488651 |
| RUNX1 | runt-related transcription factor 1 | 0.0484911 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0483069 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0468042 |
| CUL1 | cullin 1 | 0.0459787 |
| NDRG1 | N-myc downstream regulated 1 | 0.0449701 |
| PCNX1 | pecanex 1 | 0.0449571 |
| POTEF | POTE ankyrin domain family, member F | 0.0444965 |
| RPL5 | ribosomal protein L5 | 0.0442067 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0439081 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0438972 |
| PKM | pyruvate kinase, muscle | 0.0438026 |
| ANXA2 | annexin A2 | 0.043094 |
| CCDC14 | coiled-coil domain containing 14 | 0.0426937 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0426849 |
| IL6ST | interleukin 6 signal transducer | 0.0426827 |
| PRKCA | protein kinase C, alpha | 0.0423706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420691 |
| ANXA5 | annexin A5 | 0.0420283 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0419813 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.041875 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0418053 |
| SEPTIN9 | septin 9 | 0.0414615 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0413265 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0410498 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0409658 |
| HIP1 | huntingtin interacting protein 1 | 0.04045 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.040378 |
| USP47 | ubiquitin specific peptidase 47 | 0.0400701 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0396661 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.039585 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.039577 |
| TUBB | tubulin, beta class I | 0.0392362 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0391653 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0390468 |
| COG6 | component of oligomeric golgi complex 6 | 0.0379647 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0378083 |
| RPL12 | ribosomal protein L12 | 0.0377722 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0373623 |
| CBX3 | chromobox homolog 3 | 0.0371137 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0371052 |
| FBXO34 | F-box protein 34 | 0.0370782 |
| H1-0 | H1.0 linker histone | 0.037056 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.036378 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0362261 |
| RPL37A | ribosomal protein L37a | 0.0358322 |
| RTN4 | reticulon 4 | 0.0357371 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0357354 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0357006 |
| TPX2 | TPX2, microtubule-associated | 0.0356554 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0356286 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0356096 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0354155 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0352724 |
| AFTPH | aftiphilin | 0.0351885 |
| EGFR | epidermal growth factor receptor | 0.035174 |
| ATP13A3 | ATPase type 13A3 | 0.0350944 |
| RPS6 | ribosomal protein S6 | 0.0349495 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0348738 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0347389 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0342824 |
| FAM13A | family with sequence similarity 13, member A | 0.0340199 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0337007 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0335001 |
| LAMB1 | laminin, beta 1 | 0.0333644 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0332546 |
| SPAG9 | sperm associated antigen 9 | 0.0324481 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0324107 |
| NAV2 | neuron navigator 2 | 0.0324022 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0321122 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0319861 |
| RPL28 | ribosomal protein L28 | 0.0316677 |
| CALU | calumenin | 0.0316588 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0315103 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0314586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.140331 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0970945 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0943672 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0879205 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.078569 |
| FN1 | fibronectin 1 | -0.0733397 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0672656 |
| B2M | beta-2-microglobulin | -0.0639453 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.063458 |
| HLA-B | major histocompatibility complex, class I, B | -0.061674 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0584347 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0529717 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0485638 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0483404 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0463243 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0440063 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -0.0432964 |
| STC1 | stanniocalcin 1 | -0.0425039 |
| CLTC | clathrin, heavy chain (Hc) | -0.0414257 |
| RPL37 | ribosomal protein L37 | -0.0404287 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0399639 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0393963 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.039332 |
| CUL3 | cullin 3 | -0.0390733 |
| APP | amyloid beta (A4) precursor protein | -0.0386325 |
| SDC4 | syndecan 4 | -0.0369159 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0360356 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.035946 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0348968 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0342034 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0338323 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0338165 |
| SUCO | SUN domain containing ossification factor | -0.0335691 |
| UBXN4 | UBX domain protein 4 | -0.0335208 |
| RNF24 | ring finger protein 24 | -0.0332703 |
| OGA | O-GlcNAcase | -0.0331827 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0327651 |
| IFI44 | interferon-induced protein 44 | -0.0326713 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0324593 |
| LAMB3 | laminin, beta 3 | -0.0323548 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0319684 |
| H3-3B | H3.3 histone B | -0.0316127 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0313304 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0313219 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.031305 |
| RPL32 | ribosomal protein L32 | -0.0312882 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0310181 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.030745 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0307207 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0306217 |
| FHIT | fragile histidine triad | -0.0304521 |
| TMF1 | TATA element modulatory factor 1 | -0.0304011 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0302653 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0302311 |
| TMEM165 | transmembrane protein 165 | -0.030206 |
| FAT1 | FAT atypical cadherin 1 | -0.0295815 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0295783 |
| TMSB10 | thymosin beta 10 | -0.0294209 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0293281 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0290189 |
| CFDP1 | craniofacial development protein 1 | -0.0289516 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0287378 |
| SETBP1 | SET binding protein 1 | -0.0286174 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0283417 |
| UVRAG | UV radiation resistance associated | -0.0283182 |
| MRPL1 | mitochondrial ribosomal protein L1 | -0.028244 |
| PMM2 | phosphomannomutase 2 | -0.028232 |
| CABIN1 | calcineurin binding protein 1 | -0.0281934 |
| RPL35A | ribosomal protein L35a | -0.0281501 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0280043 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0278323 |
| RBM25 | RNA binding motif protein 25 | -0.0278085 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0276356 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0276152 |
| EGR1 | early growth response 1 | -0.0273678 |
| RUNX2 | runt-related transcription factor 2 | -0.0272557 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0271573 |
| XPO4 | exportin 4 | -0.0270401 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0268812 |
| SYNRG | synergin, gamma | -0.0268533 |
| JAZF1 | JAZF zinc finger 1 | -0.0268446 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0267465 |
| FUS | FUS RNA binding protein | -0.0266606 |
| ZMYM5 | zinc finger, MYM-type 5 | -0.0262798 |
| MYOF | myoferlin | -0.026114 |
| HBP1 | HMG-box transcription factor 1 | -0.0260588 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0260472 |
| ZNF160 | zinc finger protein 160 | -0.0260372 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0258565 |
| MATR3 | matrin 3 | -0.0258182 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.025814 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0257561 |
| NRP1 | neuropilin 1 | -0.0257453 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0256702 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0256274 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0255494 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0255386 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0255104 |
| IREB2 | iron-responsive element binding protein 2 | -0.0254493 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0254453 |
