| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.233227 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0940896 |
| ZNF292 | zinc finger protein 292 | 0.0866168 |
| ATP13A3 | ATPase type 13A3 | 0.0764026 |
| PDE8A | phosphodiesterase 8A | 0.0648808 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0640416 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0626794 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0581452 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.057824 |
| NUP58 | nucleoporin 58 | 0.0578106 |
| VIM | vimentin | 0.055041 |
| RNF145 | ring finger protein 145 | 0.0549082 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0511144 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0503067 |
| NPTN | neuroplastin | 0.0495703 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0491015 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0484035 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0482738 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0481227 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0471342 |
| DNER | delta/notch-like EGF repeat containing | 0.0471124 |
| CUL5 | cullin 5 | 0.0468761 |
| NBAS | neuroblastoma amplified sequence | 0.0463935 |
| FNIP1 | folliculin interacting protein 1 | 0.0463418 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0459877 |
| PARD3 | par-3 family cell polarity regulator | 0.0456902 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0456009 |
| JMJD1C | jumonji domain containing 1C | 0.0453718 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0451388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0449124 |
| SEC24A | SEC24 family member A | 0.0448453 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0446094 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0445779 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0430817 |
| RNF111 | ring finger protein 111 | 0.0429841 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0419557 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0418076 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0415246 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0409661 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0407265 |
| TBK1 | TANK-binding kinase 1 | 0.0406401 |
| IPO11 | importin 11 | 0.0397727 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0394485 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0392928 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0391363 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.038876 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0387952 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0379882 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0379565 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0371625 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.036849 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0365513 |
| FAM193A | family with sequence similarity 193, member A | 0.0359593 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0357523 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0356332 |
| FLNB | filamin B, beta | 0.0348007 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.034657 |
| PTEN | phosphatase and tensin homolog | 0.0346014 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0344521 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0344237 |
| DTNA | dystrobrevin, alpha | 0.0342902 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0342642 |
| SETD5 | SET domain containing 5 | 0.0340297 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0336381 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0336056 |
| ECT2 | epithelial cell transforming 2 | 0.0331777 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0331519 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0330456 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0328346 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0324303 |
| ZNF207 | zinc finger protein 207 | 0.0323845 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0323746 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0322916 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0321999 |
| TOP1 | topoisomerase (DNA) I | 0.0320974 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0320879 |
| EGFR | epidermal growth factor receptor | 0.0320289 |
| SUCO | SUN domain containing ossification factor | 0.0318999 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0316336 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0315174 |
| DIAPH3 | diaphanous-related formin 3 | 0.0314779 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.031398 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0311979 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.030663 |
| RPS21 | ribosomal protein S21 | 0.0305465 |
| TNPO1 | transportin 1 | 0.0304084 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0302366 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0301593 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0301324 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.030065 |
| RACK1 | receptor for activated C kinase 1 | 0.0300472 |
| RPL23 | ribosomal protein L23 | 0.0299755 |
| PRR16 | proline rich 16 | 0.0298377 |
| KIAA1328 | KIAA1328 | 0.0298165 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0296143 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0294813 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0293898 |
| WDR36 | WD repeat domain 36 | 0.0293362 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0293027 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0292303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.094124 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0816116 |
| AHNAK | AHNAK nucleoprotein | -0.0675884 |
| TMSB10 | thymosin beta 10 | -0.0660084 |
| CANX | calnexin | -0.0648688 |
| YBX3 | Y box binding protein 3 | -0.061176 |
| ATM | ATM serine/threonine kinase | -0.0561325 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0560041 |
| SQSTM1 | sequestosome 1 | -0.0546352 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0518915 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0456511 |
| RIGI | RNA sensor RIG-I | -0.0452683 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0449391 |
| LOC112694756 | uncharaterized LOC112694756 | -0.044726 |
| SEPTIN9 | septin 9 | -0.0444056 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0441136 |
| LMO7 | LIM domain 7 | -0.0439358 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0434826 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0433537 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0406746 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.040422 |
| BRD2 | bromodomain containing 2 | -0.0401537 |
| KIF5B | kinesin family member 5B | -0.0401311 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0400299 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0399383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0394677 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0390015 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0388248 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0385654 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0384895 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0377457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377272 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0376114 |
| PTMA | prothymosin, alpha | -0.0372248 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0371242 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0361992 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0356429 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0353199 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0353137 |
| RDX | radixin | -0.0351173 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0344506 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0339921 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0326284 |
| LMNA | lamin A/C | -0.0325233 |
| CEP250 | centrosomal protein 250kDa | -0.0322536 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0320183 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0319363 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.031538 |
| FRMD5 | FERM domain containing 5 | -0.0314631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0312758 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0309268 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0308104 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0307243 |
| CEP350 | centrosomal protein 350kDa | -0.0307189 |
| TRIM44 | tripartite motif containing 44 | -0.0307185 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.0305767 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0303184 |
| PHF3 | PHD finger protein 3 | -0.0302998 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0301005 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.030094 |
| CENPF | centromere protein F, 350/400kDa | -0.0296896 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0294111 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -0.0293733 |
| PRR11 | proline rich 11 | -0.029349 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0293389 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0290507 |
| FUS | FUS RNA binding protein | -0.029014 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0289931 |
| CDK12 | cyclin-dependent kinase 12 | -0.0289379 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0288198 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.028613 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0285267 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0285179 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0285094 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0284494 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0283692 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0282012 |
| YTHDC1 | YTH domain containing 1 | -0.0281474 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0280161 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.027926 |
| CD163L1 | CD163 molecule-like 1 | -0.0278755 |
| OGA | O-GlcNAcase | -0.0277665 |
| RBM39 | RNA binding motif protein 39 | -0.0277582 |
| GNAS | GNAS complex locus | -0.0274065 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0273666 |
| CPNE1 | copine I | -0.027331 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0272889 |
| CENPE | centromere protein E, 312kDa | -0.0270347 |
| INTS6 | integrator complex subunit 6 | -0.0269139 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.026798 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0267961 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | -0.026717 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0265816 |
| CALR | calreticulin | -0.0263868 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0263767 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0263574 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0263501 |
| DIAPH1 | diaphanous-related formin 1 | -0.0263035 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0260585 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0259617 |
