| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hydroxyurea perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hydroxyurea_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.122221 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0996454 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.083514 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0708489 |
| RNF145 | ring finger protein 145 | 0.0688238 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0628436 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0587169 |
| ZNF292 | zinc finger protein 292 | 0.0577557 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.057392 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.054423 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0442114 |
| HELZ | helicase with zinc finger | 0.0424553 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0422677 |
| RPS6 | ribosomal protein S6 | 0.0421271 |
| PELO | pelota homolog (Drosophila) | 0.0413151 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0404128 |
| NUP58 | nucleoporin 58 | 0.0401794 |
| GOLGA4 | golgin A4 | 0.0401431 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0399926 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0398878 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0386623 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0386071 |
| COG5 | component of oligomeric golgi complex 5 | 0.0377792 |
| FAM13A | family with sequence similarity 13, member A | 0.0377461 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0371581 |
| TMEM165 | transmembrane protein 165 | 0.0370672 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0369059 |
| ETNK1 | ethanolamine kinase 1 | 0.0368559 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0359163 |
| ANXA5 | annexin A5 | 0.0357246 |
| NEK7 | NIMA-related kinase 7 | 0.0349919 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0340582 |
| CDC73 | cell division cycle 73 | 0.0339967 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0336058 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0330221 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0327279 |
| OGA | O-GlcNAcase | 0.0326649 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0323214 |
| SUCO | SUN domain containing ossification factor | 0.0319936 |
| QKI | QKI, KH domain containing, RNA binding | 0.0318051 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0315719 |
| VEGFA | vascular endothelial growth factor A | 0.0315635 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.03143 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0305679 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0303941 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0302985 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302737 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0302428 |
| SPAG9 | sperm associated antigen 9 | 0.0300237 |
| RPS12 | ribosomal protein S12 | 0.0299387 |
| MT2A | metallothionein 2A | 0.0297838 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0297241 |
| RPL5 | ribosomal protein L5 | 0.0296355 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0294538 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0294436 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0294031 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0291222 |
| TFG | TRK-fused gene | 0.0291011 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0288358 |
| SETD5 | SET domain containing 5 | 0.0286196 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0285826 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0283671 |
| CD109 | CD109 molecule | 0.0282568 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0278379 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0277257 |
| CDC27 | cell division cycle 27 | 0.0271307 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0269614 |
| RLF | rearranged L-myc fusion | 0.026901 |
| GOLT1B | golgi transport 1B | 0.0268586 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0267439 |
| WTAP | Wilms tumor 1 associated protein | 0.026549 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0263274 |
| USP3 | ubiquitin specific peptidase 3 | 0.0263102 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0262013 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.026118 |
| NDRG1 | N-myc downstream regulated 1 | 0.0258332 |
| RBM39 | RNA binding motif protein 39 | 0.0256908 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0256633 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0256601 |
| TNPO3 | transportin 3 | 0.0256348 |
| FAM168B | family with sequence similarity 168, member B | 0.0256182 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0255439 |
| SFXN1 | sideroflexin 1 | 0.0254266 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0252548 |
| RNF24 | ring finger protein 24 | 0.0251381 |
| WDR43 | WD repeat domain 43 | 0.0251351 |
| TPD52 | tumor protein D52 | 0.0250871 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0250017 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0249993 |
| RAB18 | RAB18, member RAS oncogene family | 0.0244887 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0242557 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.024043 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0239963 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0239348 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0238283 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0236649 |
| JMJD1C | jumonji domain containing 1C | 0.0232686 |
| ZFR | zinc finger RNA binding protein | 0.0232566 |
| ATP13A3 | ATPase type 13A3 | 0.0231978 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0231547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.251694 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.180878 |
| NRG1 | neuregulin 1 | -0.171408 |
| ASPH | aspartate beta-hydroxylase | -0.152724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141318 |
| CANX | calnexin | -0.136297 |
| HMGA2 | high mobility group AT-hook 2 | -0.093829 |
| UBC | ubiquitin C | -0.0855887 |
| SQSTM1 | sequestosome 1 | -0.078861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0782416 |
| VCL | vinculin | -0.0761827 |
| TMSB10 | thymosin beta 10 | -0.0758397 |
| PTMA | prothymosin, alpha | -0.0674093 |
| AHNAK | AHNAK nucleoprotein | -0.0665492 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0664641 |
| ITGA1 | integrin, alpha 1 | -0.066331 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0651221 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0551721 |
| STC2 | stanniocalcin 2 | -0.05285 |
| SYT1 | synaptotagmin I | -0.0525276 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0515666 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0513391 |
| ENO1 | enolase 1, (alpha) | -0.0495373 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0476022 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0468405 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0468182 |
| MAP1B | microtubule-associated protein 1B | -0.0447626 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0446228 |
| HLA-B | major histocompatibility complex, class I, B | -0.0442643 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.042974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0419682 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.041936 |
| MCL1 | myeloid cell leukemia 1 | -0.0419144 |
| PALLD | palladin, cytoskeletal associated protein | -0.0416237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0414377 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0403498 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0402236 |
| TMSB4X | thymosin beta 4, X-linked | -0.0398929 |
| AEBP2 | AE binding protein 2 | -0.0394399 |
| INTS6 | integrator complex subunit 6 | -0.0390239 |
| RAI14 | retinoic acid induced 14 | -0.0384453 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0365615 |
| RPS27A | ribosomal protein S27a | -0.0360022 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0356885 |
| S100A6 | S100 calcium binding protein A6 | -0.0353372 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0349327 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0346868 |
| H1-0 | H1.0 linker histone | -0.0341966 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0335262 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0320528 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0317107 |
| IER3 | immediate early response 3 | -0.0316807 |
| PLIN2 | perilipin 2 | -0.0308503 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0307217 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0303364 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0303338 |
| RNF213 | ring finger protein 213 | -0.0300664 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0297075 |
| SFTPA2 | surfactant protein A2 | -0.0293305 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0290175 |
| NTN4 | netrin 4 | -0.028963 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0289617 |
| LOXL2 | lysyl oxidase-like 2 | -0.0284383 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.028386 |
| ACTG1 | actin gamma 1 | -0.0283727 |
| HDLBP | high density lipoprotein binding protein | -0.0281562 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0281443 |
| CALR | calreticulin | -0.0278779 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0278255 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0276622 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0262354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0262275 |
| FBN1 | fibrillin 1 | -0.0258877 |
| ABR | active BCR-related | -0.0258634 |
| JUN | jun proto-oncogene | -0.0257702 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0256752 |
| LRRC23 | leucine rich repeat containing 23 | -0.0255388 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0240531 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0240383 |
| BPTF | bromodomain PHD finger transcription factor | -0.023864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0237968 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0237437 |
| RRBP1 | ribosome binding protein 1 | -0.0236708 |
| CTSB | cathepsin B | -0.0235666 |
| RAD51B | RAD51 paralog B | -0.0235497 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.023411 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0234027 |
| SVIL | supervillin | -0.0227261 |
| EGR1 | early growth response 1 | -0.0226436 |
| VIM | vimentin | -0.0226269 |
| TPM4 | tropomyosin 4 | -0.0225039 |
| FHL2 | four and a half LIM domains 2 | -0.022408 |
| ACTN4 | actinin, alpha 4 | -0.0222528 |
| SMAD3 | SMAD family member 3 | -0.0221634 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0221235 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0219781 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0217834 |
| GLUL | glutamate-ammonia ligase | -0.0217832 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0216969 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216425 |
