Hyperaldosteronism Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An adrenal gland hyperfunction disease that results in the overproduction of aldosterone by the adrenal glands. (Human Disease Ontology, DOID_446)
External Link https://www.disgenet.org/browser/0/1/0/C0020428
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Genes

83 genes associated with the disease Hyperaldosteronism in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADD1 adducin 1 (alpha)
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ANGPT2 angiopoietin 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APC adenomatous polyposis coli
AR androgen receptor
ARMC5 armadillo repeat containing 5
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BDKRB2 bradykinin receptor B2
BSND barttin CLCNK-type chloride channel accessory beta subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CETP cholesteryl ester transfer protein, plasma
CLCN2 chloride channel, voltage-sensitive 2
CLCNKA chloride channel, voltage-sensitive Ka
CLCNKB chloride channel, voltage-sensitive Kb
CLSTN3 calsyntenin 3
CRH corticotropin releasing hormone
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
CYBB cytochrome b-245, beta polypeptide
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DRD2 dopamine receptor D2
EDN1 endothelin 1
FAM131A family with sequence similarity 131, member A
FLNB filamin B, beta
G6PD glucose-6-phosphate dehydrogenase
GIP gastric inhibitory polypeptide
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GRK2 G protein-coupled receptor kinase 2
GRK5 G protein-coupled receptor kinase 5
GSTA1 glutathione S-transferase alpha 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
INSR insulin receptor
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK9 potassium channel, two pore domain subfamily K, member 9
LCN2 lipocalin 2
LGALS14 lectin, galactoside-binding, soluble, 14
MEN1 multiple endocrine neoplasia I
MSR1 macrophage scavenger receptor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
OCRL oculocerebrorenal syndrome of Lowe
PCSK9 proprotein convertase subtilisin/kexin type 9
PIAS1 protein inhibitor of activated STAT, 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PRSS8 protease, serine, 8
PTH parathyroid hormone
RBAK RB-associated KRAB zinc finger
REN renin
RPTOR regulatory associated protein of MTOR, complex 1
S100A6 S100 calcium binding protein A6
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SIAH1 siah E3 ubiquitin protein ligase 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SRA1 steroid receptor RNA activator 1
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)