Hyperbilirubinemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism. (Human Disease Ontology, DOID_2741)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006932
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Genes

706 genes/proteins associated with the disease Hyperbilirubinemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 2.88009
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.88009
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.88009
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
TNF tumor necrosis factor 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.25576
BCL2L1 BCL2-like 1 2.24605
TP53 tumor protein p53 2.18936
BCL2 B-cell CLL/lymphoma 2 2.18793
PARP1 poly (ADP-ribose) polymerase 1 2.17746
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.17108
IL6 interleukin 6 2.14985
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.10941
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.10452
BAX BCL2-associated X protein 2.08776
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.05042
JUN jun proto-oncogene 2.0378
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.00233
BIRC5 baculoviral IAP repeat containing 5 1.98568
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.97655
CCNB1 cyclin B1 1.9658
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.96417
BIRC2 baculoviral IAP repeat containing 2 1.96284
CDK2 cyclin-dependent kinase 2 1.96056
GSTM1 glutathione S-transferase mu 1 1.95315
H2AFX H2A histone family, member X 1.94343
FAS Fas cell surface death receptor 1.9386
FASLG Fas ligand (TNF superfamily, member 6) 1.93353
CAT catalase 1.92928
MPO myeloperoxidase 1.92328
CCL2 chemokine (C-C motif) ligand 2 1.92058
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.91217
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.91184
TYMS thymidylate synthetase 1.8978
RB1 retinoblastoma 1 1.88688
RRM2 ribonucleotide reductase M2 1.87509
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.87492
TOP2A topoisomerase (DNA) II alpha 170kDa 1.8641
IL1B interleukin 1, beta 1.8566
GSTP1 glutathione S-transferase pi 1 1.85134
UBE2C ubiquitin-conjugating enzyme E2C 1.85116
ERBB2 erb-b2 receptor tyrosine kinase 2 1.84924
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.83912
SOD2 superoxide dismutase 2, mitochondrial 1.83771
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.83272
PRC1 protein regulator of cytokinesis 1 1.83113
GADD45A growth arrest and DNA-damage-inducible, alpha 1.83042
VCAM1 vascular cell adhesion molecule 1 1.81337
PPARG peroxisome proliferator-activated receptor gamma 1.80737
BIRC3 baculoviral IAP repeat containing 3 1.80247
EGR1 early growth response 1 1.78835
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.78207
CXCL8 chemokine (C-X-C motif) ligand 8 1.7784
VEGFA vascular endothelial growth factor A 1.77335
MAPK3 mitogen-activated protein kinase 3 1.76888
CCND1 cyclin D1 1.7681
GSK3B glycogen synthase kinase 3 beta 1.76791
MAPK1 mitogen-activated protein kinase 1 1.76013
NAMPT nicotinamide phosphoribosyltransferase 1.75281
BTG2 BTG family, member 2 1.75201
IL4 interleukin 4 1.74681
DUSP4 dual specificity phosphatase 4 1.73659
IFNG interferon, gamma 1.73557
HMOX1 heme oxygenase 1 1.72758
CCNA2 cyclin A2 1.72467
IGFBP3 insulin-like growth factor binding protein 3 1.71193
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.70988
TRIM2 tripartite motif containing 2 1.69742
SRGN serglycin 1.69742
CDK1 cyclin-dependent kinase 1 1.68996
BAD BCL2-associated agonist of cell death 1.68084
INSIG1 insulin induced gene 1 1.67289
BRCA1 breast cancer 1, early onset 1.67137
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.66792
MCL1 myeloid cell leukemia 1 1.66727
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.66339
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.66253
S100A4 S100 calcium binding protein A4 1.65996
E2F1 E2F transcription factor 1 1.65533
MGMT O-6-methylguanine-DNA methyltransferase 1.65068
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.65068
S100P S100 calcium binding protein P 1.65068
FASN fatty acid synthase 1.64842
NQO1 NAD(P)H dehydrogenase, quinone 1 1.64595
NRP1 neuropilin 1 1.64438
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.64416
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.6419
TGFB1 transforming growth factor, beta 1 1.63966
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.63406
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.62938
CXCL12 chemokine (C-X-C motif) ligand 12 1.62938
VCAN versican 1.62246
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.62176
PCNA proliferating cell nuclear antigen 1.61897
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.61552
ATF3 activating transcription factor 3 1.61318
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.59989
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.59873
RGS2 regulator of G-protein signaling 2 1.59826
ICAM1 intercellular adhesion molecule 1 1.59591
THBS1 thrombospondin 1 1.58889
FYN FYN proto-oncogene, Src family tyrosine kinase 1.58537
DDIT3 DNA-damage-inducible transcript 3 1.58279
CCNG1 cyclin G1 1.57994
PLAT plasminogen activator, tissue 1.57877
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.57618
CFLAR CASP8 and FADD-like apoptosis regulator 1.57474
TIMP1 TIMP metallopeptidase inhibitor 1 1.57114
SRXN1 sulfiredoxin 1 1.57114
MMP9 matrix metallopeptidase 9 1.56875
PMP22 peripheral myelin protein 22 1.56484
EDNRB endothelin receptor type B 1.56263
DCN decorin 1.55995
BAK1 BCL2-antagonist/killer 1 1.55921
MCM5 minichromosome maintenance complex component 5 1.55747
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.555
DUSP1 dual specificity phosphatase 1 1.55255
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.55133
VLDLR very low density lipoprotein receptor 1.5501
UNG uracil-DNA glycosylase 1.5479
F3 coagulation factor III (thromboplastin, tissue factor) 1.54766
FOS FBJ murine osteosarcoma viral oncogene homolog 1.54718
LCN2 lipocalin 2 1.54135
POR P450 (cytochrome) oxidoreductase 1.53868
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.53675
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.53407
CD44 CD44 molecule (Indian blood group) 1.53036
DDIT4 DNA-damage-inducible transcript 4 1.52889
CYCS cytochrome c, somatic 1.52616
MMP3 matrix metallopeptidase 3 1.52591
CCL3 chemokine (C-C motif) ligand 3 1.52515
TFPI2 tissue factor pathway inhibitor 2 1.5181
MAPK14 mitogen-activated protein kinase 14 1.50776
ATF5 activating transcription factor 5 1.50223
KLF6 Kruppel-like factor 6 1.49635
PRNP prion protein 1.49432
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.49432
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.48402
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.47889
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.47889
TYMP thymidine phosphorylase 1.47838
MKI67 marker of proliferation Ki-67 1.47787
RAD51 RAD51 recombinase 1.4753
LEP leptin 1.47219
MMP2 matrix metallopeptidase 2 1.46781
PTEN phosphatase and tensin homolog 1.46754
NOS2 nitric oxide synthase 2, inducible 1.46727
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.46568
TERT telomerase reverse transcriptase 1.46251
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.45617
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.45352
MAPK8 mitogen-activated protein kinase 8 1.45247
FANCG Fanconi anemia, complementation group G 1.4522
KRT8 keratin 8, type II 1.45194
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.45115
TGFBR3 transforming growth factor, beta receptor III 1.4479
RUNX3 runt-related transcription factor 3 1.4479
FSCN1 fascin actin-bundling protein 1 1.4479
IL15RA interleukin 15 receptor, alpha 1.44572
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.4449
NUSAP1 nucleolar and spindle associated protein 1 1.43809
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.43646
DUSP2 dual specificity phosphatase 2 1.4351
CDK4 cyclin-dependent kinase 4 1.43401
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.43157
OSBPL10 oxysterol binding protein-like 10 1.42994
CCND2 cyclin D2 1.42642
CXCL10 chemokine (C-X-C motif) ligand 10 1.42589
CCNE1 cyclin E1 1.42129
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.42101
KIF20A kinesin family member 20A 1.42101
CDKN3 cyclin-dependent kinase inhibitor 3 1.41856
SOD1 superoxide dismutase 1, soluble 1.41802
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.4164
MAPK9 mitogen-activated protein kinase 9 1.41559
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.4098
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.40925
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.40568
G0S2 G0/G1 switch 2 1.40486
FOSL1 FOS-like antigen 1 1.40316
IL1A interleukin 1, alpha 1.40148
ACKR3 atypical chemokine receptor 3 1.40064
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.39813
IL12B interleukin 12B 1.39785
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.39702
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.39338
PLAU plasminogen activator, urokinase 1.39114
NFE2L2 nuclear factor, erythroid 2-like 2 1.38918
HMGA2 high mobility group AT-hook 2 1.38327
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.3827
CTSL cathepsin L 1.37676
ALAD aminolevulinate dehydratase 1.37475
ALB albumin 1.37103
TNNI3 troponin I type 3 (cardiac) 1.3699
IGFBP5 insulin-like growth factor binding protein 5 1.36677
RARB retinoic acid receptor, beta 1.36476
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.36361
S100A11 S100 calcium binding protein A11 1.36361
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.36361
NOS3 nitric oxide synthase 3 (endothelial cell) 1.36332
EGFR epidermal growth factor receptor 1.36332
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.3619
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.36104
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.35877
HSPA8 heat shock 70kDa protein 8 1.35531
SPP1 secreted phosphoprotein 1 1.35502
TTK TTK protein kinase 1.35444
IL15 interleukin 15 1.35415
CTGF connective tissue growth factor 1.35386
WNT5A wingless-type MMTV integration site family, member 5A 1.35127
CD36 CD36 molecule (thrombospondin receptor) 1.34983
PELO pelota homolog (Drosophila) 1.34782
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.34752
TIMP3 TIMP metallopeptidase inhibitor 3 1.34547
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.34256
CDC20 cell division cycle 20 1.34198
GJA1 gap junction protein, alpha 1, 43kDa 1.34082
STAT1 signal transducer and activator of transcription 1, 91kDa 1.34082
CLU clusterin 1.3385
ADM adrenomedullin 1.3382
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.3382
LIMCH1 LIM and calponin homology domains 1 1.33731
KIF23 kinesin family member 23 1.33672
ISG15 ISG15 ubiquitin-like modifier 1.33672
KLF2 Kruppel-like factor 2 1.33672
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.33287
NPPB natriuretic peptide B 1.3311
GADD45B growth arrest and DNA-damage-inducible, beta 1.3311
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.32816
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.32816
HMGN3 high mobility group nucleosomal binding domain 3 1.32726
MAGEA6 melanoma antigen family A6 1.32726
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.32577
IER3 immediate early response 3 1.32577
IRS1 insulin receptor substrate 1 1.32399
ADIPOQ adiponectin, C1Q and collagen domain containing 1.32339
COL1A1 collagen, type I, alpha 1 1.32251
ODC1 ornithine decarboxylase 1 1.32221
CCNB2 cyclin B2 1.32044
S100A10 S100 calcium binding protein A10 1.31985
LMNB1 lamin B1 1.31985
ASS1 argininosuccinate synthase 1 1.31985
CENPF centromere protein F, 350/400kDa 1.31716
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.31476
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.31446
STC2 stanniocalcin 2 1.31446
IL1RN interleukin 1 receptor antagonist 1.31357
NPY neuropeptide Y 1.31357
CD151 CD151 molecule (Raph blood group) 1.31297
TGFB2 transforming growth factor, beta 2 1.31178
HSPA1B heat shock 70kDa protein 1B 1.31178
HSPA1A heat shock 70kDa protein 1A 1.31148
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.31119
IGFBP4 insulin-like growth factor binding protein 4 1.30941
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.30941
CD274 CD274 molecule 1.30819
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.30666
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.30666
GPNMB glycoprotein (transmembrane) nmb 1.30666
FOSL2 FOS-like antigen 2 1.30666
HIST1H4C histone cluster 1, H4c 1.3036
CRYAB crystallin, alpha B 1.30177
SGK1 serum/glucocorticoid regulated kinase 1 1.30177
GCLC glutamate-cysteine ligase, catalytic subunit 1.29966
CXCR4 chemokine (C-X-C motif) receptor 4 1.29843
BID BH3 interacting domain death agonist 1.2975
EGF epidermal growth factor 1.2941
ECH1 enoyl CoA hydratase 1, peroxisomal 1.29379
CSF1 colony stimulating factor 1 (macrophage) 1.29379
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.29133
SP1 Sp1 transcription factor 1.29041
ATF4 activating transcription factor 4 1.28889
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.28889
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.28796
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.28734
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.2861
MXI1 MAX interactor 1, dimerization protein 1.2861
IL2 interleukin 2 1.28549
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.28425
RBM34 RNA binding motif protein 34 1.28303
CD14 CD14 molecule 1.28241
CDA cytidine deaminase 1.27813
PLA1A phospholipase A1 member A 1.27782
PLK1 polo-like kinase 1 1.27689
HLA-A major histocompatibility complex, class I, A 1.27471
SORBS1 sorbin and SH3 domain containing 1 1.27409
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.27378
COL4A2 collagen, type IV, alpha 2 1.27378
SLIT2 slit homolog 2 (Drosophila) 1.27378
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.27039
FAM129A family with sequence similarity 129, member A 1.27009
PDE4B phosphodiesterase 4B, cAMP-specific 1.26794
SMAD2 SMAD family member 2 1.26794
CP ceruloplasmin (ferroxidase) 1.26607
SPON1 spondin 1, extracellular matrix protein 1.26607
GSN gelsolin 1.26545
LIF leukemia inhibitory factor 1.26545
BTG1 B-cell translocation gene 1, anti-proliferative 1.26545
ELOVL6 ELOVL fatty acid elongase 6 1.26545
PPARA peroxisome proliferator-activated receptor alpha 1.26298
CD8A CD8a molecule 1.26236
BLM Bloom syndrome, RecQ helicase-like 1.26236
CDC6 cell division cycle 6 1.26113
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.25868
BAMBI BMP and activin membrane-bound inhibitor 1.25868
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.25868
GFRA1 GDNF family receptor alpha 1 1.25838
SPON2 spondin 2, extracellular matrix protein 1.25838
PDLIM7 PDZ and LIM domain 7 (enigma) 1.25838
IFRD1 interferon-related developmental regulator 1 1.25682
TPD52 tumor protein D52 1.25494
LMNA lamin A/C 1.25245
MCM6 minichromosome maintenance complex component 6 1.25245
MOK MOK protein kinase 1.25152
MT1A metallothionein 1A 1.25152
IFITM1 interferon induced transmembrane protein 1 1.25121
AURKA aurora kinase A 1.25028
CTSH cathepsin H 1.24781
MELK maternal embryonic leucine zipper kinase 1.24781
IGFBP7 insulin-like growth factor binding protein 7 1.2475
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.2475
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.24623
RBM17 RNA binding motif protein 17 1.24496
GRB10 growth factor receptor-bound protein 10 1.24401
PLK4 polo-like kinase 4 1.24401
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.24401
IL13RA1 interleukin 13 receptor, alpha 1 1.24056
TK1 thymidine kinase 1, soluble 1.23993
TAGLN transgelin 1.23993
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.23806
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.23806
ZDHHC14 zinc finger, DHHC-type containing 14 1.23743
AIF1L allograft inflammatory factor 1-like 1.23712
LMCD1 LIM and cysteine-rich domains 1 1.23712
GSTT1 glutathione S-transferase theta 1 1.2352
BMP4 bone morphogenetic protein 4 1.23392
ITGB5 integrin, beta 5 1.23392
TPM1 tropomyosin 1 (alpha) 1.23392
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.23392
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.23169
HHEX hematopoietically expressed homeobox 1.23042
MAP2K1 mitogen-activated protein kinase kinase 1 1.22979
NGF nerve growth factor (beta polypeptide) 1.22979
PRDX2 peroxiredoxin 2 1.2279
IRF1 interferon regulatory factor 1 1.2279
PTPRC protein tyrosine phosphatase, receptor type, C 1.22696
CDKN2A cyclin-dependent kinase inhibitor 2A 1.22599
MMP1 matrix metallopeptidase 1 1.22469
LHFPL2 lipoma HMGIC fusion partner-like 2 1.22404
G6PC glucose-6-phosphatase, catalytic subunit 1.22404
S100A9 S100 calcium binding protein A9 1.22404
FPR1 formyl peptide receptor 1 1.22404
GEM GTP binding protein overexpressed in skeletal muscle 1.22371
ACADVL acyl-CoA dehydrogenase, very long chain 1.22371
DUSP10 dual specificity phosphatase 10 1.22048
PPARD peroxisome proliferator-activated receptor delta 1.21984
GDF15 growth differentiation factor 15 1.21823
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.21823
IL18 interleukin 18 1.21823
BUB3 BUB3 mitotic checkpoint protein 1.21759
ZFP36L1 ZFP36 ring finger protein-like 1 1.21727
AXL AXL receptor tyrosine kinase 1.21727
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.21631
CXCR6 chemokine (C-X-C motif) receptor 6 1.21599
RUNX1 runt-related transcription factor 1 1.21402
RELN reelin 1.21402
HIST1H1C histone cluster 1, H1c 1.21402
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.21402
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.21402
RFC3 replication factor C (activator 1) 3, 38kDa 1.21402
MPZL2 myelin protein zero-like 2 1.21141
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.21043
VIM vimentin 1.20913
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.20848
OGG1 8-oxoguanine DNA glycosylase 1.20848
FGF2 fibroblast growth factor 2 (basic) 1.20784
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.20784
LYN LYN proto-oncogene, Src family tyrosine kinase 1.20784
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.20558
GFI1 growth factor independent 1 transcription repressor 1.20526
NFIB nuclear factor I/B 1.2046
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.20295
EPO erythropoietin 1.2013
APAF1 apoptotic peptidase activating factor 1 1.2013
BBC3 BCL2 binding component 3 1.19933
FHL1 four and a half LIM domains 1 1.19868
CYBA cytochrome b-245, alpha polypeptide 1.19737
SDC2 syndecan 2 1.19574
IL10 interleukin 10 1.19279
CD40LG CD40 ligand 1.18718
ACSL3 acyl-CoA synthetase long-chain family member 3 1.18685
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.18685
IL6R interleukin 6 receptor 1.18685
GLS glutaminase 1.18424
APP amyloid beta (A4) precursor protein 1.18326
LPL lipoprotein lipase 1.18259
VASN vasorin 1.18226
HSPB1 heat shock 27kDa protein 1 1.18159
AOX1 aldehyde oxidase 1 1.18126
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.18126
ANXA1 annexin A1 1.17993
CCND3 cyclin D3 1.17993
GBP2 guanylate binding protein 2, interferon-inducible 1.1786
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.1786
FBN1 fibrillin 1 1.17827
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.17563
SESN1 sestrin 1 1.17563
COL3A1 collagen, type III, alpha 1 1.17497
GPX3 glutathione peroxidase 3 1.17333
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.173
RRM1 ribonucleotide reductase M1 1.173
INPP1 inositol polyphosphate-1-phosphatase 1.17168
ACTA2 actin, alpha 2, smooth muscle, aorta 1.17134
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.16766
ANXA4 annexin A4 1.16766
CFB complement factor B 1.165
BCL6 B-cell CLL/lymphoma 6 1.165
AREG amphiregulin 1.16368
PECAM1 platelet/endothelial cell adhesion molecule 1 1.16269
FADS1 fatty acid desaturase 1 1.16236
RAD50 RAD50 homolog (S. cerevisiae) 1.16236
EMP1 epithelial membrane protein 1 1.16236
PRL prolactin 1.16236
FAM46A family with sequence similarity 46, member A 1.16203
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 1.16203
NUPR1 nuclear protein, transcriptional regulator, 1 1.16203
SLBP stem-loop binding protein 1.16203
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.1617
EDN1 endothelin 1 1.16035
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.15695
IL12A interleukin 12A 1.1556
PLAUR plasminogen activator, urokinase receptor 1.1556
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.15492
ACAA2 acetyl-CoA acyltransferase 2 1.15458
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.15256
HSPA2 heat shock 70kDa protein 2 1.15223
CSTA cystatin A (stefin A) 1.15223
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.15223
CDC25A cell division cycle 25A 1.15223
SMOC2 SPARC related modular calcium binding 2 1.15189
BCL2A1 BCL2-related protein A1 1.14989
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.14954
IL33R interleukin 33 receptor 1.14954
FN1 fibronectin 1 1.14816
ACTB actin, beta 1.14781
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.14781
SRPX sushi-repeat containing protein, X-linked 1.14747
XAF1 XIAP associated factor 1 1.14747
GABARAPL1 GABA(A) receptor-associated protein like 1 1.14747
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.14747
SORBS2 sorbin and SH3 domain containing 2 1.14747
LDHB lactate dehydrogenase B 1.14713
IL1R2 interleukin 1 receptor, type II 1.14713
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.1461
CAV1 caveolin 1, caveolae protein, 22kDa 1.14473
SCARB1 scavenger receptor class B, member 1 1.14302
LBH limb bud and heart development 1.14302
HADH hydroxyacyl-CoA dehydrogenase 1.14234
PHGDH phosphoglycerate dehydrogenase 1.14234
GJB1 gap junction protein, beta 1, 32kDa 1.142
MCM4 minichromosome maintenance complex component 4 1.13963
NCF2 neutrophil cytosolic factor 2 1.13963
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.13963
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.13862
RAD54L RAD54-like (S. cerevisiae) 1.13862
PMEL premelanosome protein 1.13758
MAP2K6 mitogen-activated protein kinase kinase 6 1.13724
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.13724
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.13518
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.13484
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.13484
AR androgen receptor 1.13484
PKP2 plakophilin 2 1.13381
COL1A2 collagen, type I, alpha 2 1.13109
KRT19 keratin 19, type I 1.13041
GPX1 glutathione peroxidase 1 1.12973
RSRP1 arginine/serine-rich protein 1 1.12973
DKK3 dickkopf WNT signaling pathway inhibitor 3 1.12973
TRIB2 tribbles pseudokinase 2 1.12973
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.1294
SULF1 sulfatase 1 1.1294
GULP1 GULP, engulfment adaptor PTB domain containing 1 1.1294
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.12838
PRKCD protein kinase C, delta 1.12703
CCL5 chemokine (C-C motif) ligand 5 1.12668
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.12634
DHCR24 24-dehydrocholesterol reductase 1.12564
IL17RB interleukin 17 receptor B 1.1253
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.1253
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.12357
CCNG2 cyclin G2 1.12357
CXCL5 chemokine (C-X-C motif) ligand 5 1.12357
TNC tenascin C 1.12323
IL13 interleukin 13 1.12254
EMP2 epithelial membrane protein 2 1.12151
HDAC4 histone deacetylase 4 1.12151
GHR growth hormone receptor 1.12117
RAD23A RAD23 homolog A (S. cerevisiae) 1.12117
RANBP1 RAN binding protein 1 1.12117
F2 coagulation factor II (thrombin) 1.1198
DIABLO diablo, IAP-binding mitochondrial protein 1.11911
IL16 interleukin 16 1.11775
ASL argininosuccinate lyase 1.11707
SDS serine dehydratase 1.11707
RIPK2 receptor-interacting serine-threonine kinase 2 1.11707
CKB creatine kinase, brain 1.11466
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.11431
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.11325
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.11325
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 1.1129
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.1129
GCG glucagon 1.11255
KLF4 Kruppel-like factor 4 (gut) 1.1122
PLIN2 perilipin 2 1.11011
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.10942
DBF4 DBF4 zinc finger 1.10942
TPM2 tropomyosin 2 (beta) 1.10907
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.10907
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.10907
KDR kinase insert domain receptor 1.10872
GPR1 G protein-coupled receptor 1 1.10734
MGP matrix Gla protein 1.10596
OTC ornithine carbamoyltransferase 1.10562
HIST2H2BE histone cluster 2, H2be 1.10527
CDCA7 cell division cycle associated 7 1.10527
BASP1 brain abundant, membrane attached signal protein 1 1.10493
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 1.10493
IFI30 interferon, gamma-inducible protein 30 1.10493
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.10493
NOX4 NADPH oxidase 4 1.10388
MSMO1 methylsterol monooxygenase 1 1.10175
CDK5 cyclin-dependent kinase 5 1.10175
MCM2 minichromosome maintenance complex component 2 1.10175
STOM stomatin 1.1014
DPYD dihydropyrimidine dehydrogenase 1.09963
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.09751
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.09751
EMP3 epithelial membrane protein 3 1.09751
RBPMS RNA binding protein with multiple splicing 1.09751
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.09751
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 1.09751
TP53I3 tumor protein p53 inducible protein 3 1.09436
FSHB follicle stimulating hormone, beta polypeptide 1.09262
AURKB aurora kinase B 1.09119
INHBA inhibin, beta A 1.09119
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.09011
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.0894
F2R coagulation factor II (thrombin) receptor 1.0894
CCNE2 cyclin E2 1.08726
FLT1 fms-related tyrosine kinase 1 1.08726
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.0869
KLK3 kallikrein-related peptidase 3 1.08549
CTH cystathionine gamma-lyase 1.08337
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.08301
TPD52L1 tumor protein D52-like 1 1.08301
BCL2L2 BCL2-like 2 1.08301
SMC4 structural maintenance of chromosomes 4 1.08301
FAM171A1 family with sequence similarity 171, member A1 1.08231
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 1.08196
BMP2 bone morphogenetic protein 2 1.08126
IL5 interleukin 5 1.07983
SORT1 sortilin 1 1.07983
LYZ lysozyme 1.07983
PON1 paraoxonase 1 1.07983
PPIF peptidylprolyl isomerase F 1.07911
KIF20B kinesin family member 20B 1.07911
DHFR dihydrofolate reductase 1.07732
TUBA4A tubulin, alpha 4a 1.07625
APOE apolipoprotein E 1.07625
EGR2 early growth response 2 1.07553
WRN Werner syndrome, RecQ helicase-like 1.07518
TJP1 tight junction protein 1 1.07376
CCL7 chemokine (C-C motif) ligand 7 1.0734
TRAF2 TNF receptor-associated factor 2 1.07269
BTG3 BTG family, member 3 1.07269
CXCL11 chemokine (C-X-C motif) ligand 11 1.07269
MTUS1 microtubule associated tumor suppressor 1 1.07234
XDH xanthine dehydrogenase 1.07128
GTSE1 G-2 and S-phase expressed 1 1.06917
TOB1 transducer of ERBB2, 1 1.06917
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.06625
RPS6 ribosomal protein S6 1.06625
LGALS3 lectin, galactoside-binding, soluble, 3 1.06625
TMEM97 transmembrane protein 97 1.06588
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.06588
ISG20 interferon stimulated exonuclease gene 20kDa 1.06588
PROCR protein C receptor, endothelial 1.06552
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.06552
LUM lumican 1.06552
CCL20 chemokine (C-C motif) ligand 20 1.06406
HBEGF heparin-binding EGF-like growth factor 1.06406
SREBF1 sterol regulatory element binding transcription factor 1 1.06406
TRAF1 TNF receptor-associated factor 1 1.06297
POLB polymerase (DNA directed), beta 1.06297
IGF2R insulin-like growth factor 2 receptor 1.06261
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 1.06261
XPC xeroderma pigmentosum, complementation group C 1.06261
KYNU kynureninase 1.06261
CALB1 calbindin 1, 28kDa 1.06225
CALR calreticulin 1.06044
PDGFB platelet-derived growth factor beta polypeptide 1.06044
TFE3 transcription factor binding to IGHM enhancer 3 1.06008
MCAM melanoma cell adhesion molecule 1.05936
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.05936
PLSCR2 phospholipid scramblase 2 1.059
ARG1 arginase 1 1.05864
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.05864
PLTP phospholipid transfer protein 1.05573
PRKCE protein kinase C, epsilon 1.05498
STMN1 stathmin 1 1.05312
PRKCB protein kinase C, beta 1.05312
S100A8 S100 calcium binding protein A8 1.05312
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 1.05312
GPER1 G protein-coupled estrogen receptor 1 1.05274
CD69 CD69 molecule 1.05274
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.05274
PSAP prosaposin 1.05237
ANKRD28 ankyrin repeat domain 28 1.05237
IL23A interleukin 23, alpha subunit p19 1.04978
SMAD3 SMAD family member 3 1.04941
EPHX2 epoxide hydrolase 2, cytoplasmic 1.04757
MFGE8 milk fat globule-EGF factor 8 protein 1.04684
TPX2 TPX2, microtubule-associated 1.04647
TACC3 transforming, acidic coiled-coil containing protein 3 1.04647
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.04647
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.04647
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.04611
BLMH bleomycin hydrolase 1.04611
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.04611
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 1.04574
TRIM38 tripartite motif containing 38 1.04501
CTHRC1 collagen triple helix repeat containing 1 1.04501
USP36 ubiquitin specific peptidase 36 1.04501
TAC1 tachykinin, precursor 1 1.04501
HLA-G major histocompatibility complex, class I, G 1.04465
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.04427
MAP2K3 mitogen-activated protein kinase kinase 3 1.04352
IFNGR1 interferon gamma receptor 1 1.04352
TGFA transforming growth factor, alpha 1.04239
THY1 Thy-1 cell surface antigen 1.04051
LHB luteinizing hormone beta polypeptide 1.03939
TGM2 transglutaminase 2 1.03901
HLA-DRA major histocompatibility complex, class II, DR alpha 1.03827
RBL1 retinoblastoma-like 1 1.03789
COL6A3 collagen, type VI, alpha 3 1.03752
ACACB acetyl-CoA carboxylase beta 1.03715
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.03715
CDCA8 cell division cycle associated 8 1.03715
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.03715
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.03567
ACSL1 acyl-CoA synthetase long-chain family member 1 1.0353
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.03456
PF4 platelet factor 4 1.03419
MCM10 minichromosome maintenance complex component 10 1.03419
LIG1 ligase I, DNA, ATP-dependent 1.03419
HDAC9 histone deacetylase 9 1.03308
PARM1 prostate androgen-regulated mucin-like protein 1 1.03197
INHBC inhibin, beta C 1.03197
BIK BCL2-interacting killer (apoptosis-inducing) 1.03159
TRIB1 tribbles pseudokinase 1 1.03159
SPC25 SPC25, NDC80 kinetochore complex component 1.03122
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.03122
TXNIP thioredoxin interacting protein 1.03046
ANPEP alanyl (membrane) aminopeptidase 1.02858
CDCA3 cell division cycle associated 3 1.02821
MGST1 microsomal glutathione S-transferase 1 1.02708
MPC2 mitochondrial pyruvate carrier 2 1.02634
CKMT1B creatine kinase, mitochondrial 1B 1.02596
DOK4 docking protein 4 1.02559
ALCAM activated leukocyte cell adhesion molecule 1.02559
ALPK2 alpha-kinase 2 1.02559
ITGAV integrin, alpha V 1.02559
NXN nucleoredoxin 1.02559
GSTA2 glutathione S-transferase alpha 2 1.02373
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.02299
FEN1 flap structure-specific endonuclease 1 1.02262
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.02262
CHEK2 checkpoint kinase 2 1.02225
AKAP12 A kinase (PRKA) anchor protein 12 1.02003
PHACTR2 phosphatase and actin regulator 2 1.02003
RGS16 regulator of G-protein signaling 16 1.02003
RORA RAR-related orphan receptor A 1.01966
SDC1 syndecan 1 1.01966
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 1.01966
ARHGAP24 Rho GTPase activating protein 24 1.01966
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.01966
CDK14 cyclin-dependent kinase 14 1.01928
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.01739
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.01739
PROM1 prominin 1 1.01739
RACGAP1 Rac GTPase activating protein 1 1.01739
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.01739
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.01701
CAPN1 calpain 1, (mu/I) large subunit 1.01701
ALPL alkaline phosphatase, liver/bone/kidney 1.01549
NDRG1 N-myc downstream regulated 1 1.01549
NRF1 nuclear respiratory factor 1 1.01474
NRIP1 nuclear receptor interacting protein 1 1.01474
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.01437
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.01437
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.01437
LBP lipopolysaccharide binding protein 1.01437
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 1.01399
MIR22HG MIR22 host gene 1.01361
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.01212
KITLG KIT ligand 1.01212