Hypercalcemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D006934
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Genes

158 genes/proteins associated with the disease Hypercalcemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
PTH parathyroid hormone 2.88009
PTHLH parathyroid hormone-like hormone 2.88009
IL6 interleukin 6 2.88009
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.88009
TNF tumor necrosis factor 2.88009
CALCA calcitonin-related polypeptide alpha 2.88009
CASR calcium-sensing receptor 2.88009
KL klotho 2.88009
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.88009
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.88009
CALCR calcitonin receptor 2.88009
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.88009
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.18086
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.05858
TGFB1 transforming growth factor, beta 1 1.93813
VEGFA vascular endothelial growth factor A 1.90525
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.87975
BCL2 B-cell CLL/lymphoma 2 1.85204
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.83735
REN renin 1.82814
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.78625
CCL2 chemokine (C-C motif) ligand 2 1.70657
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.70265
IL10 interleukin 10 1.6906
IL4 interleukin 4 1.68506
BAX BCL2-associated X protein 1.68169
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.65864
SPP1 secreted phosphoprotein 1 1.65599
IL1B interleukin 1, beta 1.65402
EGFR epidermal growth factor receptor 1.61131
IFNG interferon, gamma 1.60897
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.60267
IL2 interleukin 2 1.57306
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.54499
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.53061
CXCL8 chemokine (C-X-C motif) ligand 8 1.49278
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.44382
CCND1 cyclin D1 1.42696
CTSB cathepsin B 1.41613
MAPK1 mitogen-activated protein kinase 1 1.41505
EGR1 early growth response 1 1.41063
ALB albumin 1.41035
FAS Fas cell surface death receptor 1.4087
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.4065
BIRC5 baculoviral IAP repeat containing 5 1.38412
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.381
CA2 carbonic anhydrase II 1.36933
CCL3 chemokine (C-C motif) ligand 3 1.36476
PRL prolactin 1.36218
NOS3 nitric oxide synthase 3 (endothelial cell) 1.35792
FOS FBJ murine osteosarcoma viral oncogene homolog 1.35415
COL1A1 collagen, type I, alpha 1 1.35242
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.34983
TP53 tumor protein p53 1.34955
HMOX1 heme oxygenase 1 1.3484
GSR glutathione reductase 1.33966
SOD2 superoxide dismutase 2, mitochondrial 1.33909
GDF15 growth differentiation factor 15 1.32637
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.32547
BAD BCL2-associated agonist of cell death 1.32488
POMC proopiomelanocortin 1.31807
FASLG Fas ligand (TNF superfamily, member 6) 1.31237
MCL1 myeloid cell leukemia 1 1.30788
BGLAP bone gamma-carboxyglutamate (gla) protein 1.29502
IGF1 insulin-like growth factor 1 (somatomedin C) 1.29103
MAPK3 mitogen-activated protein kinase 3 1.28088
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.26452
MMP2 matrix metallopeptidase 2 1.26236
RB1 retinoblastoma 1 1.24623
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.24623
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.24056
CYCS cytochrome c, somatic 1.2368
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.23137
MAP2K2 mitogen-activated protein kinase kinase 2 1.23106
MAP2K1 mitogen-activated protein kinase kinase 1 1.23011
JAK1 Janus kinase 1 1.22339
IGF2 insulin-like growth factor 2 1.22274
KRT8 keratin 8, type II 1.22274
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.22274
INS insulin 1.22016
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.21206
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.20946
GJA1 gap junction protein, alpha 1, 43kDa 1.20816
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.20654
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.19999
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.19704
BHLHE40 basic helix-loop-helix family, member e40 1.19574
NCOA1 nuclear receptor coactivator 1 1.19574
GCG glucagon 1.19574
GSTP1 glutathione S-transferase pi 1 1.19113
SFTPB surfactant protein B 1.19014
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.18554
DUSP1 dual specificity phosphatase 1 1.18424
DDIT3 DNA-damage-inducible transcript 3 1.18391
S100G S100 calcium binding protein G 1.18259
CAT catalase 1.18093
JUN jun proto-oncogene 1.17629
LYN LYN proto-oncogene, Src family tyrosine kinase 1.17168
MBP myelin basic protein 1.17034
EGF epidermal growth factor 1.15223
GFAP glial fibrillary acidic protein 1.15089
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.14885
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.14747
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.14644
RXRA retinoid X receptor, alpha 1.13381
KDR kinase insert domain receptor 1.13381
PPARG peroxisome proliferator-activated receptor gamma 1.13041
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.12599
PRKCE protein kinase C, epsilon 1.12599
BDNF brain-derived neurotrophic factor 1.11707
MKI67 marker of proliferation Ki-67 1.11151
IL1A interleukin 1, alpha 1.10977
GPX1 glutathione peroxidase 1 1.10838
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.10631
BCL2L1 BCL2-like 1 1.10562
SOD1 superoxide dismutase 1, soluble 1.10317
EDN1 endothelin 1 1.09892
G6PD glucose-6-phosphate dehydrogenase 1.09751
CDC42 cell division cycle 42 1.0919
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.08904
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.08904
CD38 CD38 molecule 1.08904
LEP leptin 1.0869
NOS2 nitric oxide synthase 2, inducible 1.08337
ICAM1 intercellular adhesion molecule 1 1.08337
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.08091
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.07376
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.07305
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.07305
PARP1 poly (ADP-ribose) polymerase 1 1.06552
NCOR2 nuclear receptor corepressor 2 1.06297
CKB creatine kinase, brain 1.06188
TOB1 transducer of ERBB2, 1 1.059
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.05685
LPL lipoprotein lipase 1.05685
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.0561
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.05461
ATM ATM serine/threonine kinase 1.05423
CD14 CD14 molecule 1.05089
B2M beta-2-microglobulin 1.04904
MMP9 matrix metallopeptidase 9 1.04904
BAG1 BCL2-associated athanogene 1.04684
MAPK8 mitogen-activated protein kinase 8 1.04276
CTSD cathepsin D 1.04163
THRA thyroid hormone receptor, alpha 1.04126
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.03976
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.03939
KRT17 keratin 17, type I 1.03197
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.02783
GSTM1 glutathione S-transferase mu 1 1.02559
MUC1 mucin 1, cell surface associated 1.02485
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.02262
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.02077
CDK2 cyclin-dependent kinase 2 1.02003
FN1 fibronectin 1 1.01512
MAPK14 mitogen-activated protein kinase 14 1.01361
TJP1 tight junction protein 1 1.01286
IGFBP5 insulin-like growth factor binding protein 5 1.01286