Hypercalcemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

754 genes co-occuring with the disease Hypercalcemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PTH parathyroid hormone 4.0
PTHLH parathyroid hormone-like hormone 3.936
CASR calcium-sensing receptor 3.643
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 3.255
FGF23 fibroblast growth factor 23 3.203
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 3.194
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 3.064
MYOM2 myomesin 2 3.045
ALB albumin 3.024
MEN1 multiple endocrine neoplasia I 2.986
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.976
CDC73 cell division cycle 73 2.971
PTH1R parathyroid hormone 1 receptor 2.887
BGLAP bone gamma-carboxyglutamate (gla) protein 2.838
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.81
GC group-specific component (vitamin D binding protein) 2.746
KL klotho 2.702
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.698
B2M beta-2-microglobulin 2.677
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 2.675
SDC1 syndecan 1 2.64
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.617
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.613
ACP5 acid phosphatase 5, tartrate resistant 2.612
SOST sclerostin 2.534
GCM2 glial cells missing homolog 2 (Drosophila) 2.527
ACE angiotensin I converting enzyme 2.512
IL6 interleukin 6 2.511
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.507
FDPS farnesyl diphosphate synthase 2.502
CD38 CD38 molecule 2.496
RUNX2 runt-related transcription factor 2 2.429
AVP arginine vasopressin 2.429
ALPL alkaline phosphatase, liver/bone/kidney 2.408
REN renin 2.382
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.373
SPP1 secreted phosphoprotein 1 2.361
GAST gastrin 2.353
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.334
POMC proopiomelanocortin 2.333
CRP C-reactive protein, pentraxin-related 2.332
TNF tumor necrosis factor 2.326
TGFB1 transforming growth factor, beta 1 2.323
MGP matrix Gla protein 2.319
INS insulin 2.303
AQP2 aquaporin 2 (collecting duct) 2.282
CTSK cathepsin K 2.273
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.265
PHEX phosphate regulating endopeptidase homolog, X-linked 2.26
IGF1 insulin-like growth factor 1 (somatomedin C) 2.26
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 2.236
CD4 CD4 molecule 2.234
AHSG alpha-2-HS-glycoprotein 2.228
IL1B interleukin 1, beta 2.216
NCAM1 neural cell adhesion molecule 1 2.216
PRL prolactin 2.209
EPO erythropoietin 2.201
TP53 tumor protein p53 2.194
S100G S100 calcium binding protein G 2.182
ESR1 estrogen receptor 1 2.161
SLAMF7 SLAM family member 7 2.158
IL1A interleukin 1, alpha 2.138
CCND1 cyclin D1 2.137
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.11
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.105
IBSP integrin-binding sialoprotein 2.104
SP7 Sp7 transcription factor 2.104
IFNG interferon, gamma 2.102
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.091
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.087
CD8A CD8a molecule 2.083
CHGA chromogranin A 2.079
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.079
IL2 interleukin 2 2.072
IL11 interleukin 11 2.071
RET ret proto-oncogene 2.067
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.066
BMP2 bone morphogenetic protein 2 2.058
CLDN16 claudin 16 2.038
SST somatostatin 2.037
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.033
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.028
CD19 CD19 molecule 2.012
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.009
FGF7 fibroblast growth factor 7 2.009
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.008
CSF3 colony stimulating factor 3 (granulocyte) 2.002
HBZ hemoglobin, zeta 1.997
SCT secretin 1.989
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.982
EMP1 epithelial membrane protein 1 1.981
FGF5 fibroblast growth factor 5 1.978
PTPRC protein tyrosine phosphatase, receptor type, C 1.978
FGF3 fibroblast growth factor 3 1.971
DMP1 dentin matrix acidic phosphoprotein 1 1.967
FGF6 fibroblast growth factor 6 1.963
FGF16 fibroblast growth factor 16 1.962
FGF18 fibroblast growth factor 18 1.962
FGF17 fibroblast growth factor 17 1.962
FGF22 fibroblast growth factor 22 1.961
GGPS1 geranylgeranyl diphosphate synthase 1 1.96
FGF20 fibroblast growth factor 20 1.959
SPINK1 serine peptidase inhibitor, Kazal type 1 1.959
BCL2 B-cell CLL/lymphoma 2 1.959
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.954
FGF4 fibroblast growth factor 4 1.953
FGF8 fibroblast growth factor 8 (androgen-induced) 1.953
VIP vasoactive intestinal peptide 1.952
FGF9 fibroblast growth factor 9 1.952
FGF10 fibroblast growth factor 10 1.944
FGFR3 fibroblast growth factor receptor 3 1.944
LRP2 low density lipoprotein receptor-related protein 2 1.936
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.936
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.932
IL10 interleukin 10 1.929
DNAH8 dynein, axonemal, heavy chain 8 1.924
GCG glucagon 1.924
NSD2 nuclear receptor binding SET domain protein 2 1.908
SYP synaptophysin 1.908
CD79A CD79a molecule, immunoglobulin-associated alpha 1.904
CD5 CD5 molecule 1.9
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.892
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.889
CLDN14 claudin 14 1.889
ELN elastin 1.887
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.881
ENO2 enolase 2 (gamma, neuronal) 1.878
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.875
CXCR4 chemokine (C-X-C motif) receptor 4 1.873
CD274 CD274 molecule 1.873
LRP5 low density lipoprotein receptor-related protein 5 1.87
KLK3 kallikrein-related peptidase 3 1.869
CD34 CD34 molecule 1.868
CSF1 colony stimulating factor 1 (macrophage) 1.866
MEPE matrix extracellular phosphoglycoprotein 1.857
CALCR calcitonin receptor 1.856
MME membrane metallo-endopeptidase 1.855
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.852
PTH2R parathyroid hormone 2 receptor 1.848
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.84
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.837
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.833
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.833
AVPR2 arginine vasopressin receptor 2 1.832
CXCL8 chemokine (C-X-C motif) ligand 8 1.829
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.828
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.822
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.822
PAX5 paired box 5 1.821
CLDN19 claudin 19 1.82
CCL3 chemokine (C-C motif) ligand 3 1.817
CXCL12 chemokine (C-X-C motif) ligand 12 1.807
CD7 CD7 molecule 1.806
FGFR1 fibroblast growth factor receptor 1 1.803
ACTB actin, beta 1.802
EGFR epidermal growth factor receptor 1.801
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.8
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.799
IFNA1 interferon, alpha 1 1.798
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.793
IL17A interleukin 17A 1.791
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.79
ERBB2 erb-b2 receptor tyrosine kinase 2 1.79
TG thyroglobulin 1.789
PPY pancreatic polypeptide 1.785
FOS FBJ murine osteosarcoma viral oncogene homolog 1.769
IRF4 interferon regulatory factor 4 1.769
STC1 stanniocalcin 1 1.768
MMP9 matrix metallopeptidase 9 1.763
PRSS1 protease, serine, 1 (trypsin 1) 1.762
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.759
MSX2 msh homeobox 2 1.759
TENT5C terminal nucleotidyltransferase 5C 1.754
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.746
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.743
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.743
PXDN peroxidasin 1.741
PXDNL peroxidasin-like 1.74
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.736
CAMP cathelicidin antimicrobial peptide 1.736
EGF epidermal growth factor 1.734
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.733
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.731
ALPP alkaline phosphatase, placental 1.729
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.727
APOM apolipoprotein M 1.727
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.725
MAPK3 mitogen-activated protein kinase 3 1.724
WNK4 WNK lysine deficient protein kinase 4 1.724
ALPG alkaline phosphatase, germ cell 1.723
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.72
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.719
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.717
F2 coagulation factor II (thrombin) 1.717
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.716
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.716
CDKN2A cyclin-dependent kinase inhibitor 2A 1.712
TRPM6 transient receptor potential cation channel, subfamily M, member 6 1.706
IL4 interleukin 4 1.702
COL1A2 collagen, type I, alpha 2 1.698
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.697
IL3 interleukin 3 1.694
CRBN cereblon 1.694
F3 coagulation factor III (thromboplastin, tissue factor) 1.694
CTRC chymotrypsin C (caldecrin) 1.693
FGF2 fibroblast growth factor 2 (basic) 1.692
IFNA2 interferon, alpha 2 1.687
AFP alpha-fetoprotein 1.685
JUN jun proto-oncogene 1.683
ALPI alkaline phosphatase, intestinal 1.682
CALB1 calbindin 1, 28kDa 1.68
TGFA transforming growth factor, alpha 1.679
IFNA5 interferon, alpha 5 1.678
IFNA17 interferon, alpha 17 1.676
CCL2 chemokine (C-C motif) ligand 2 1.676
FN1 fibronectin 1 1.676
IFNA7 interferon, alpha 7 1.674
IFNA16 interferon, alpha 16 1.671
IFNA14 interferon, alpha 14 1.671
IFNA10 interferon, alpha 10 1.671
IFNA6 interferon, alpha 6 1.67
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.67
IFNA8 interferon, alpha 8 1.67
IFNA13 interferon, alpha 13 1.67
IFNA21 interferon, alpha 21 1.67
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.669
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.665
IFNA4 interferon, alpha 4 1.665
GPRC5D G protein-coupled receptor, class C, group 5, member D 1.658
CD2 CD2 molecule 1.658
KRAS Kirsten rat sarcoma viral oncogene homolog 1.658
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.651
CKS1B CDC28 protein kinase regulatory subunit 1B 1.65
ALK anaplastic lymphoma receptor tyrosine kinase 1.644
VCAM1 vascular cell adhesion molecule 1 1.643
EDN1 endothelin 1 1.636
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.635
FAM20C family with sequence similarity 20, member C 1.634
PGR progesterone receptor 1.63
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.616
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 1.615
COL1A1 collagen, type I, alpha 1 1.615
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.613
DCSTAMP dendrocyte expressed seven transmembrane protein 1.611
CKM creatine kinase, muscle 1.61
PTEN phosphatase and tensin homolog 1.606
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.603
GHRH growth hormone releasing hormone 1.603
CKMT1B creatine kinase, mitochondrial 1B 1.602
CKB creatine kinase, brain 1.602
SEPTIN4 septin 4 1.599
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.599
SFRP4 secreted frizzled-related protein 4 1.598
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.591
ASPG asparaginase 1.59
GNAS GNAS complex locus 1.586
MB myoglobin 1.586
BMP7 bone morphogenetic protein 7 1.582
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.579
FOXP3 forkhead box P3 1.574
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.573
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.573
CREB1 cAMP responsive element binding protein 1 1.563
CD28 CD28 molecule 1.56
GTF2I general transcription factor IIi 1.559
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.557
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.554
CD44 CD44 molecule (Indian blood group) 1.554
ARRB2 arrestin, beta 2 1.552
KRT7 keratin 7, type II 1.547
CLCN5 chloride channel, voltage-sensitive 5 1.546
HDAC9 histone deacetylase 9 1.544
PTH2 parathyroid hormone 2 1.541
LEP leptin 1.538
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.535
CSH2 chorionic somatomammotropin hormone 2 1.533
PDCD1 programmed cell death 1 1.53
NPPA natriuretic peptide A 1.527
BCL2L1 BCL2-like 1 1.527
CCK cholecystokinin 1.521
BCL6 B-cell CLL/lymphoma 6 1.52
CALML5 calmodulin-like 5 1.518
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.516
CALML3 calmodulin-like 3 1.514
DNTT DNA nucleotidylexotransferase 1.514
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.509
CALML4 calmodulin-like 4 1.509
CALML6 calmodulin-like 6 1.509
ANXA5 annexin A5 1.506
UMOD uromodulin 1.503
ICAM1 intercellular adhesion molecule 1 1.502
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.502
IHH indian hedgehog 1.501
MUC1 mucin 1, cell surface associated 1.5
IGFBP3 insulin-like growth factor binding protein 3 1.5
ARRB1 arrestin, beta 1 1.494
PHOSPHO1 phosphatase, orphan 1 1.489
KDR kinase insert domain receptor 1.489
CSF1R colony stimulating factor 1 receptor 1.486
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.483
NPPB natriuretic peptide B 1.48
CD80 CD80 molecule 1.476
PPARG peroxisome proliferator-activated receptor gamma 1.474
CRH corticotropin releasing hormone 1.47
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.468
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.468
STC2 stanniocalcin 2 1.467
XPO1 exportin 1 1.467
FGFR4 fibroblast growth factor receptor 4 1.467
SMAD3 SMAD family member 3 1.466
FCRL5 Fc receptor-like 5 1.466
FRZB frizzled-related protein 1.463
MCL1 myeloid cell leukemia 1 1.462
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.461
NF1 neurofibromin 1 1.459
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.455
CCN2 cellular communication network factor 2 1.451
DHCR7 7-dehydrocholesterol reductase 1.45
LRP6 low density lipoprotein receptor-related protein 6 1.45
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.449
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.449
CLDN2 claudin 2 1.447
SLAMF1 signaling lymphocytic activation molecule family member 1 1.441
MMP2 matrix metallopeptidase 2 1.438
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.438
CLCNKB chloride channel, voltage-sensitive Kb 1.437
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.437
GATA3 GATA binding protein 3 1.436
BMP4 bone morphogenetic protein 4 1.436
BAX BCL2-associated X protein 1.433
OXA1L oxidase (cytochrome c) assembly 1-like 1.433
RHOA ras homolog family member A 1.426
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.426
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.425
CD40 CD40 molecule, TNF receptor superfamily member 5 1.425
CCND3 cyclin D3 1.424
GTF2IRD1 GTF2I repeat domain containing 1 1.424
TLR4 toll-like receptor 4 1.423
BSND barttin CLCNK-type chloride channel accessory beta subunit 1.421
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.421
GRHPR glyoxylate reductase/hydroxypyruvate reductase 1.421
NKX2-1 NK2 homeobox 1 1.421
CD33 CD33 molecule 1.419
AGXT alanine-glyoxylate aminotransferase 1.417
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.417
TAC1 tachykinin, precursor 1 1.415
CD86 CD86 molecule 1.414
MPO myeloperoxidase 1.412
PRUNE2 prune homolog 2 (Drosophila) 1.411
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.409
TRPM7 transient receptor potential cation channel, subfamily M, member 7 1.409
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.408
IL15 interleukin 15 1.406
CALCA calcitonin-related polypeptide alpha 1.405
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.405
CD22 CD22 molecule 1.399
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.397
TPO thyroid peroxidase 1.395
HLA-G major histocompatibility complex, class I, G 1.391
PECAM1 platelet/endothelial cell adhesion molecule 1 1.39
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.389
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.389
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.383
ANXA2 annexin A2 1.383
MMP13 matrix metallopeptidase 13 1.38
AR androgen receptor 1.38
PARP1 poly (ADP-ribose) polymerase 1 1.375
IL18 interleukin 18 1.375
CLCN7 chloride channel, voltage-sensitive 7 1.375
JAG1 jagged 1 1.373
CST3 cystatin C 1.369
LIMK1 LIM domain kinase 1 1.369
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.369
CD27 CD27 molecule 1.364
SFRP2 secreted frizzled-related protein 2 1.364
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.363
TRH thyrotropin-releasing hormone 1.363
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.36
IL7 interleukin 7 1.359
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.356
BTK Bruton agammaglobulinemia tyrosine kinase 1.354
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.353
FGF13 fibroblast growth factor 13 1.351
OCRL oculocerebrorenal syndrome of Lowe 1.351
WNK1 WNK lysine deficient protein kinase 1 1.351
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.35
WT1 Wilms tumor 1 1.348
PDIA3 protein disulfide isomerase family A, member 3 1.347
JAK2 Janus kinase 2 1.344
FKBP10 FK506 binding protein 10, 65 kDa 1.344
PRSS58 protease, serine, 58 1.343
CA2 carbonic anhydrase II 1.342
CD68 CD68 molecule 1.339
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.339
PAX8 paired box 8 1.338
JUND jun D proto-oncogene 1.338
ACE2 angiotensin I converting enzyme 2 1.337
HAMP hepcidin antimicrobial peptide 1.336
IGF2 insulin-like growth factor 2 1.335
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.335
IL5 interleukin 5 1.335
SOX9 SRY (sex determining region Y)-box 9 1.334
CYCS cytochrome c, somatic 1.332
GSK3B glycogen synthase kinase 3 beta 1.332
WNT3A wingless-type MMTV integration site family, member 3A 1.33
CDX2 caudal type homeobox 2 1.329
CDK4 cyclin-dependent kinase 4 1.327
XBP1 X-box binding protein 1 1.326
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.325
ADIPOQ adiponectin, C1Q and collagen domain containing 1.324
CCNL2 cyclin L2 1.324
WNT5A wingless-type MMTV integration site family, member 5A 1.323
KRT20 keratin 20, type I 1.318
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.317
AIRE autoimmune regulator 1.316
TSHR thyroid stimulating hormone receptor 1.313
ADCK1 aarF domain containing kinase 1 1.312
GRP gastrin-releasing peptide 1.311
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.31
BRCA1 breast cancer 1, early onset 1.304
FKBP6 FK506 binding protein 6, 36kDa 1.304
EGR1 early growth response 1 1.303
SNAI1 snail family zinc finger 1 1.3
CPA1 carboxypeptidase A1 (pancreatic) 1.297
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.295
PRDM1 PR domain containing 1, with ZNF domain 1.293
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.292
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.29
SMAD2 SMAD family member 2 1.29
ANKH ANKH inorganic pyrophosphate transport regulator 1.29
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.289
XPR1 xenotropic and polytropic retrovirus receptor 1 1.288
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.288
LCN2 lipocalin 2 1.287
LOX lysyl oxidase 1.286
NOTCH1 notch 1 1.285
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.285
CDKN3 cyclin-dependent kinase inhibitor 3 1.283
ATM ATM serine/threonine kinase 1.281
PNLIP pancreatic lipase 1.28
RXRA retinoid X receptor, alpha 1.28
CEP70 centrosomal protein 70kDa 1.278
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 1.278
TRAF3 TNF receptor-associated factor 3 1.277
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.273
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.272
OSCAR osteoclast associated, immunoglobulin-like receptor 1.272
APOE apolipoprotein E 1.271
STIM1 stromal interaction molecule 1 1.27
CD99 CD99 molecule 1.265
SMAD4 SMAD family member 4 1.264
MET MET proto-oncogene, receptor tyrosine kinase 1.264
LTA lymphotoxin alpha 1.263
LGALS3 lectin, galactoside-binding, soluble, 3 1.262
TLR2 toll-like receptor 2 1.26
FZD9 frizzled class receptor 9 1.256
HRH2 histamine receptor H2 1.255
SDF4 stromal cell derived factor 4 1.253
BIRC5 baculoviral IAP repeat containing 5 1.252
CHSY3 chondroitin sulfate synthase 3 1.249
BMP6 bone morphogenetic protein 6 1.248
MYH14 myosin, heavy chain 14, non-muscle 1.247
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.246
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.246
IL13 interleukin 13 1.246
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.244
ANPEP alanyl (membrane) aminopeptidase 1.244
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.244
NOG noggin 1.243
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.24
IGF1R insulin-like growth factor 1 receptor 1.24
GTF2IRD2 GTF2I repeat domain containing 2 1.238
GHRL ghrelin/obestatin prepropeptide 1.236
VWF von Willebrand factor 1.236
TTR transthyretin 1.236
FLT3 fms-related tyrosine kinase 3 1.236
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.235
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.23
CCL5 chemokine (C-C motif) ligand 5 1.227
PLPPR4 phospholipid phosphatase related 4 1.222
KNG1 kininogen 1 1.222
KITLG KIT ligand 1.222
FGFR2 fibroblast growth factor receptor 2 1.221
NGF nerve growth factor (beta polypeptide) 1.221
GH2 growth hormone 2 1.219
ADM adrenomedullin 1.218
IGLL5 immunoglobulin lambda-like polypeptide 5 1.218
TBL2 transducin (beta)-like 2 1.217
MMP1 matrix metallopeptidase 1 1.217
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.216
CTRL chymotrypsin-like 1.216
GJA1 gap junction protein, alpha 1, 43kDa 1.215
STAT1 signal transducer and activator of transcription 1, 91kDa 1.215
HNF4A hepatocyte nuclear factor 4, alpha 1.213
TCF3 transcription factor 3 1.213
KRT5 keratin 5, type II 1.212
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 1.212
GH1 growth hormone 1 1.212
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.21
EP300 E1A binding protein p300 1.21
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.209
H3C12 H3 clustered histone 12 1.209
BRCA2 breast cancer 2, early onset 1.209
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.207
NOS3 nitric oxide synthase 3 (endothelial cell) 1.206
H3-3B H3.3 histone B 1.205
NT5E 5'-nucleotidase, ecto (CD73) 1.202
CCND2 cyclin D2 1.202
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 1.201
STK39 serine threonine kinase 39 1.198
TAGLN transgelin 1.198
PCNA proliferating cell nuclear antigen 1.196
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.196
CEL carboxyl ester lipase 1.196
FLT1 fms-related tyrosine kinase 1 1.194
ORAI1 ORAI calcium release-activated calcium modulator 1 1.193
RARA retinoic acid receptor, alpha 1.192
OSTM1 osteopetrosis associated transmembrane protein 1 1.19
CDK6 cyclin-dependent kinase 6 1.189
WNT10B wingless-type MMTV integration site family, member 10B 1.188
IL6R interleukin 6 receptor 1.188
HDAC6 histone deacetylase 6 1.186
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.186
CD40LG CD40 ligand 1.185
ARG1 arginase 1 1.184
CD99L2 CD99 molecule-like 2 1.184
CD200 CD200 molecule 1.184
KRT19 keratin 19, type I 1.183
IFNB1 interferon, beta 1, fibroblast 1.182
LCK LCK proto-oncogene, Src family tyrosine kinase 1.181
GAS6 growth arrest-specific 6 1.18
MAP2K1 mitogen-activated protein kinase kinase 1 1.18
CXCL10 chemokine (C-X-C motif) ligand 10 1.178
NPY neuropeptide Y 1.178
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.176
TFRC transferrin receptor 1.176
TBX1 T-box 1 1.176
TGFBR1 transforming growth factor, beta receptor 1 1.176
GTF2IRD2B GTF2I repeat domain containing 2B 1.175
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.175
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.174
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.173
IAPP islet amyloid polypeptide 1.172
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.171
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.17
RHO rhodopsin 1.169
SPN sialophorin 1.167
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.166
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.166
H3-4 H3.4 histone, cluster member 1.166
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.165
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.165
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.164
POSTN periostin, osteoblast specific factor 1.164
H3-5 H3.5 histone 1.162
IL2RA interleukin 2 receptor, alpha 1.161
H3C13 H3 clustered histone 13 1.161
PRTN3 proteinase 3 1.16
SAG S-antigen; retina and pineal gland (arrestin) 1.16
OXT oxytocin/neurophysin I prepropeptide 1.159
FASLG Fas ligand (TNF superfamily, member 6) 1.158
AREG amphiregulin 1.157
SP1 Sp1 transcription factor 1.157
SPI1 Spi-1 proto-oncogene 1.156
CA9 carbonic anhydrase IX 1.154
GGCX gamma-glutamyl carboxylase 1.151
MAPK8 mitogen-activated protein kinase 8 1.15
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.15
TCHP trichoplein, keratin filament binding 1.149
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.148
ITGB7 integrin, beta 7 1.147
ENG endoglin 1.147
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 1.145
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.145
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.144
CD1A CD1a molecule 1.143
FURIN furin (paired basic amino acid cleaving enzyme) 1.141
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.141
DPP4 dipeptidyl-peptidase 4 1.14
STX16 syntaxin 16 1.139
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.139
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.137
CD52 CD52 molecule 1.136
PRF1 perforin 1 (pore forming protein) 1.136
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.134
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.132
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.131
SIRT1 sirtuin 1 1.131
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.13
SCN5A sodium channel, voltage gated, type V alpha subunit 1.128
WNT1 wingless-type MMTV integration site family, member 1 1.128
HNF1B HNF1 homeobox B 1.128
GLI2 GLI family zinc finger 2 1.126
HP haptoglobin 1.124
HRAS Harvey rat sarcoma viral oncogene homolog 1.124
TGFB2 transforming growth factor, beta 2 1.124
CAV1 caveolin 1, caveolae protein, 22kDa 1.123
INSR insulin receptor 1.123
CDK2 cyclin-dependent kinase 2 1.123
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.121
CD163 CD163 molecule 1.119
CD1D CD1d molecule 1.118
NTS neurotensin 1.117
SGK1 serum/glucocorticoid regulated kinase 1 1.116
MYD88 myeloid differentiation primary response 88 1.116
SSTR2 somatostatin receptor 2 1.115
AXL AXL receptor tyrosine kinase 1.114
CTSB cathepsin B 1.114
CTSS cathepsin S 1.113
LDLR low density lipoprotein receptor 1.112
ADAM17 ADAM metallopeptidase domain 17 1.111
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 1.111
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.109
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.108
TSC2 tuberous sclerosis 2 1.107
CCR1 chemokine (C-C motif) receptor 1 1.103
ADRB2 adrenoceptor beta 2, surface 1.102
THBS1 thrombospondin 1 1.102
CD9 CD9 molecule 1.101
DEFB4A defensin, beta 4A 1.1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.098
S100A6 S100 calcium binding protein A6 1.097
FLNA filamin A, alpha 1.097
ADA adenosine deaminase 1.097
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.095
CHUK conserved helix-loop-helix ubiquitous kinase 1.094
GPX3 glutathione peroxidase 3 1.092
DICER1 dicer 1, ribonuclease type III 1.092
OCSTAMP osteoclast stimulatory transmembrane protein 1.091
CD1E CD1e molecule 1.091
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.09
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.088
PDCD1LG2 programmed cell death 1 ligand 2 1.087
ANXA8 annexin A8 1.086
AQP3 aquaporin 3 (Gill blood group) 1.086
ZFX zinc finger protein, X-linked 1.086
CCNA1 cyclin A1 1.086
CD81 CD81 molecule 1.086
VTN vitronectin 1.086
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.085
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.085
CD1B CD1b molecule 1.084
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.083
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.083
THPO thrombopoietin 1.083
HMOX1 heme oxygenase 1 1.082
SELE selectin E 1.078
XDH xanthine dehydrogenase 1.077
CP ceruloplasmin (ferroxidase) 1.075
CALR calreticulin 1.075
MSTN myostatin 1.074
NFE2L2 nuclear factor, erythroid 2-like 2 1.074
KLHL3 kelch-like family member 3 1.073
RYR1 ryanodine receptor 1 (skeletal) 1.073
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.072
CRTAP cartilage associated protein 1.072
HDAC4 histone deacetylase 4 1.071
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 1.07
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.069
AIP aryl hydrocarbon receptor interacting protein 1.069
AXIN1 axin 1 1.068
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.067
LEF1 lymphoid enhancer-binding factor 1 1.067
HAVCR1 hepatitis A virus cellular receptor 1 1.066
CD1C CD1c molecule 1.065
CCR2 chemokine (C-C motif) receptor 2 1.064
AURKA aurora kinase A 1.063
CLIP2 CAP-GLY domain containing linker protein 2 1.063
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.063
IDO1 indoleamine 2,3-dioxygenase 1 1.062
LAG3 lymphocyte-activation gene 3 1.061
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.061
FGF1 fibroblast growth factor 1 (acidic) 1.061
CENPV centromere protein V 1.06
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.06
GDNF glial cell derived neurotrophic factor 1.059
THBD thrombomodulin 1.059
FGF19 fibroblast growth factor 19 1.058
CLDN10 claudin 10 1.058
RYR2 ryanodine receptor 2 (cardiac) 1.056
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.056
OGA O-GlcNAcase 1.055
MAPK14 mitogen-activated protein kinase 14 1.054
BCR breakpoint cluster region 1.054
CALB2 calbindin 2 1.054
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 1.052
SOX2 SRY (sex determining region Y)-box 2 1.052
SHH sonic hedgehog 1.051
RTP2 receptor (chemosensory) transporter protein 2 1.051
CD247 CD247 molecule 1.05
SCTR secretin receptor 1.05
EPAS1 endothelial PAS domain protein 1 1.049
TIGAR TP53 induced glycolysis regulatory phosphatase 1.049
TREX2 three prime repair exonuclease 2 1.049
HSPA4 heat shock 70kDa protein 4 1.049
EFNB2 ephrin-B2 1.048
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.048
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.041
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.04
GDF2 growth differentiation factor 2 1.039
UCMA upper zone of growth plate and cartilage matrix associated 1.039
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.039
TIMP1 TIMP metallopeptidase inhibitor 1 1.039
CTRB1 chymotrypsinogen B1 1.038
PLAU plasminogen activator, urokinase 1.038
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.037
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 1.036
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.036
AVPR1A arginine vasopressin receptor 1A 1.034
GLP1R glucagon-like peptide 1 receptor 1.034
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 1.034
CD47 CD47 molecule 1.033
CTRB2 chymotrypsinogen B2 1.031
ARID1A AT rich interactive domain 1A (SWI-like) 1.031
TMPRSS2 transmembrane protease, serine 2 1.03
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.03
CCNA2 cyclin A2 1.029
HIC1 hypermethylated in cancer 1 1.027
LIF leukemia inhibitory factor 1.026
GPX2 glutathione peroxidase 2 1.026
CCL4 chemokine (C-C motif) ligand 4 1.025
BCL7B B-cell CLL/lymphoma 7B 1.025
BECN1 beclin 1, autophagy related 1.025
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.025
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.024
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 1.022
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.02
GLI1 GLI family zinc finger 1 1.018
CD276 CD276 molecule 1.017
TERT telomerase reverse transcriptase 1.016
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.014
IFITM5 interferon induced transmembrane protein 5 1.013
SMAD9 SMAD family member 9 1.012
OPRM1 opioid receptor, mu 1 1.012
JAK1 Janus kinase 1 1.011
BMP1 bone morphogenetic protein 1 1.009
TCF4 transcription factor 4 1.009
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.008
NOTCH2 notch 2 1.008
STX1A syntaxin 1A (brain) 1.007
PLG plasminogen 1.006
MAPK11 mitogen-activated protein kinase 11 1.006
DCN decorin 1.005
MED4 mediator complex subunit 4 1.005
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.002
ADAM10 ADAM metallopeptidase domain 10 1.001
NKX3-1 NK3 homeobox 1 1.001
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.001
NCOA1 nuclear receptor coactivator 1 1.001
ACAN aggrecan 1.0
WNK3 WNK lysine deficient protein kinase 3 1.0
GDF15 growth differentiation factor 15 1.0
GSR glutathione reductase 1.0