| Symbol |
Name |
Standardized Value |
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H)
|
4.0
|
|
CBS
|
cystathionine-beta-synthase
|
3.581
|
|
MTR
|
5-methyltetrahydrofolate-homocysteine methyltransferase
|
3.359
|
|
BHMT
|
betaine--homocysteine S-methyltransferase
|
3.094
|
|
MTRR
|
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
|
3.049
|
|
CTH
|
cystathionine gamma-lyase
|
2.926
|
|
F2
|
coagulation factor II (thrombin)
|
2.848
|
|
SERPINC1
|
serpin peptidase inhibitor, clade C (antithrombin), member 1
|
2.678
|
|
MMACHC
|
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
|
2.638
|
|
APOE
|
apolipoprotein E
|
2.636
|
|
AHCY
|
adenosylhomocysteinase
|
2.621
|
|
NOS3
|
nitric oxide synthase 3 (endothelial cell)
|
2.56
|
|
CRP
|
C-reactive protein, pentraxin-related
|
2.56
|
|
DDAH2
|
dimethylarginine dimethylaminohydrolase 2
|
2.516
|
|
DDAH1
|
dimethylarginine dimethylaminohydrolase 1
|
2.476
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.433
|
|
TCN2
|
transcobalamin II
|
2.432
|
|
MPST
|
mercaptopyruvate sulfurtransferase
|
2.393
|
|
IL6
|
interleukin 6
|
2.391
|
|
ALB
|
albumin
|
2.372
|
|
MTHFD1
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
|
2.337
|
|
INS
|
insulin
|
2.317
|
|
IL1B
|
interleukin 1, beta
|
2.294
|
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
2.288
|
|
PLG
|
plasminogen
|
2.274
|
|
PON1
|
paraoxonase 1
|
2.255
|
|
AGT
|
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
|
2.245
|
|
GPX3
|
glutathione peroxidase 3
|
2.238
|
|
LMBRD1
|
LMBR1 domain containing 1
|
2.235
|
|
TNF
|
tumor necrosis factor
|
2.235
|
|
MMADHC
|
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
|
2.233
|
|
GPX7
|
glutathione peroxidase 7
|
2.227
|
|
APOB
|
apolipoprotein B
|
2.225
|
|
APOA1
|
apolipoprotein A-I
|
2.221
|
|
PLAT
|
plasminogen activator, tissue
|
2.217
|
|
GPX8
|
glutathione peroxidase 8 (putative)
|
2.216
|
|
GPX5
|
glutathione peroxidase 5
|
2.215
|
|
GNMT
|
glycine N-methyltransferase
|
2.215
|
|
GPX6
|
glutathione peroxidase 6
|
2.212
|
|
GPX2
|
glutathione peroxidase 2
|
2.212
|
|
VCAM1
|
vascular cell adhesion molecule 1
|
2.208
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.177
|
|
MMP9
|
matrix metallopeptidase 9
|
2.17
|
|
EDN1
|
endothelin 1
|
2.165
|
|
THBD
|
thrombomodulin
|
2.157
|
|
MARS1
|
methionyl-tRNA synthetase 1
|
2.148
|
|
VWF
|
von Willebrand factor
|
2.146
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
2.146
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.144
|
|
ACE
|
angiotensin I converting enzyme
|
2.139
|
|
MARS2
|
methionyl-tRNA synthetase 2, mitochondrial
|
2.123
|
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family)
|
2.094
|
|
APP
|
amyloid beta (A4) precursor protein
|
2.083
|
|
DHFR
|
dihydrofolate reductase
|
2.082
|
|
COMT
|
catechol-O-methyltransferase
|
2.076
|
|
REN
|
renin
|
2.062
|
|
NOX4
|
NADPH oxidase 4
|
2.059
|
|
SHMT1
|
serine hydroxymethyltransferase 1 (soluble)
|
2.055
|
|
F5
|
coagulation factor V (proaccelerin, labile factor)
|
2.034
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.019
|
|
HSPA5
|
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
|
2.017
|
|
CASP1
|
caspase 1, apoptosis-related cysteine peptidase
|
2.007
|
|
MAT1A
|
methionine adenosyltransferase I, alpha
|
2.0
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
1.989
|
|
DHFR2
|
dihydrofolate reductase 2
|
1.988
|
|
CD320
|
CD320 molecule
|
1.979
|
|
HMOX1
|
heme oxygenase 1
|
1.979
|
|
TXN
|
thioredoxin
|
1.953
|
|
PEMT
|
phosphatidylethanolamine N-methyltransferase
|
1.948
|
|
SIRT1
|
sirtuin 1
|
1.947
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
1.94
|
|
SELE
|
selectin E
|
1.914
|
|
SLC19A1
|
solute carrier family 19 (folate transporter), member 1
|
1.909
|
|
BHMT2
|
betaine--homocysteine S-methyltransferase 2
|
1.908
|
|
XDH
|
xanthine dehydrogenase
|
1.893
|
|
BLMH
|
bleomycin hydrolase
|
1.882
|
|
TGFB1
|
transforming growth factor, beta 1
|
1.881
|
|
LPA
|
lipoprotein, Lp(a)
|
1.88
|
|
NNMT
|
nicotinamide N-methyltransferase
|
1.877
|
|
SELP
|
selectin P (granule membrane protein 140kDa, antigen CD62)
|
1.872
|
|
CYBB
|
cytochrome b-245, beta polypeptide
|
1.872
|
|
APOH
|
apolipoprotein H (beta-2-glycoprotein I)
|
1.868
|
|
IL18
|
interleukin 18
|
1.862
|
|
LDLR
|
low density lipoprotein receptor
|
1.859
|
|
ATF6
|
activating transcription factor 6
|
1.846
|
|
ELN
|
elastin
|
1.845
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
1.842
|
|
PSEN1
|
presenilin 1
|
1.837
|
|
MMP2
|
matrix metallopeptidase 2
|
1.833
|
|
LEP
|
leptin
|
1.829
|
|
MMUT
|
methylmalonyl-CoA mutase
|
1.827
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
1.819
|
|
F7
|
coagulation factor VII (serum prothrombin conversion accelerator)
|
1.817
|
|
NLRP3
|
NLR family, pyrin domain containing 3
|
1.814
|
|
CYBA
|
cytochrome b-245, alpha polypeptide
|
1.81
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
1.804
|
|
BACE1
|
beta-site APP-cleaving enzyme 1
|
1.802
|
|
SLC46A1
|
solute carrier family 46 (folate transporter), member 1
|
1.799
|
|
CYCS
|
cytochrome c, somatic
|
1.798
|
|
TIMP4
|
TIMP metallopeptidase inhibitor 4
|
1.798
|
|
CHDH
|
choline dehydrogenase
|
1.795
|
|
TYMS
|
thymidylate synthetase
|
1.789
|
|
DNMT3B
|
DNA (cytosine-5-)-methyltransferase 3 beta
|
1.788
|
|
IL10
|
interleukin 10
|
1.785
|
|
GPT
|
glutamic-pyruvate transaminase (alanine aminotransferase)
|
1.785
|
|
BDNF
|
brain-derived neurotrophic factor
|
1.784
|
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing
|
1.783
|
|
PPARA
|
peroxisome proliferator-activated receptor alpha
|
1.781
|
|
SREBF1
|
sterol regulatory element binding transcription factor 1
|
1.769
|
|
NFE2L2
|
nuclear factor, erythroid 2-like 2
|
1.767
|
|
TLR4
|
toll-like receptor 4
|
1.757
|
|
LRTOMT
|
leucine rich transmembrane and O-methyltransferase domain containing
|
1.757
|
|
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1
|
1.751
|
|
IL1A
|
interleukin 1, alpha
|
1.748
|
|
SREBF2
|
sterol regulatory element binding transcription factor 2
|
1.741
|
|
ERN1
|
endoplasmic reticulum to nucleus signaling 1
|
1.735
|
|
CST3
|
cystatin C
|
1.734
|
|
ACTB
|
actin, beta
|
1.731
|
|
NCF1
|
neutrophil cytosolic factor 1
|
1.731
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
1.729
|
|
F8
|
coagulation factor VIII, procoagulant component
|
1.728
|
|
ABCA1
|
ATP-binding cassette, sub-family A (ABC1), member 1
|
1.726
|
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
1.721
|
|
SQOR
|
sulfide quinone oxidoreductase
|
1.717
|
|
BCL2
|
B-cell CLL/lymphoma 2
|
1.708
|
|
SCARB1
|
scavenger receptor class B, member 1
|
1.707
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
1.705
|
|
DDIT3
|
DNA-damage-inducible transcript 3
|
1.695
|
|
DYRK1A
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
|
1.687
|
|
MMAA
|
methylmalonic aciduria (cobalamin deficiency) cblA type
|
1.686
|
|
GSR
|
glutathione reductase
|
1.684
|
|
CUBN
|
cubilin (intrinsic factor-cobalamin receptor)
|
1.684
|
|
IFNG
|
interferon, gamma
|
1.681
|
|
EPO
|
erythropoietin
|
1.678
|
|
JUN
|
jun proto-oncogene
|
1.671
|
|
PXDN
|
peroxidasin
|
1.665
|
|
PIK3CD
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
|
1.662
|
|
PIK3CB
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
|
1.661
|
|
NOS1
|
nitric oxide synthase 1 (neuronal)
|
1.66
|
|
MTOR
|
mechanistic target of rapamycin (serine/threonine kinase)
|
1.659
|
|
PPARGC1A
|
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
|
1.659
|
|
PXDNL
|
peroxidasin-like
|
1.659
|
|
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
1.657
|
|
PTH
|
parathyroid hormone
|
1.657
|
|
CD36
|
CD36 molecule (thrombospondin receptor)
|
1.654
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
1.652
|
|
KNG1
|
kininogen 1
|
1.651
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
1.65
|
|
XBP1
|
X-box binding protein 1
|
1.646
|
|
LCMT1
|
leucine carboxyl methyltransferase 1
|
1.632
|
|
AGTR1
|
angiotensin II receptor, type 1
|
1.632
|
|
AHCYL2
|
adenosylhomocysteinase-like 2
|
1.629
|
|
SCARB2
|
scavenger receptor class B, member 2
|
1.624
|
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
1.624
|
|
MAPT
|
microtubule-associated protein tau
|
1.623
|
|
IGF1
|
insulin-like growth factor 1 (somatomedin C)
|
1.62
|
|
ABCD4
|
ATP-binding cassette, sub-family D (ALD), member 4
|
1.62
|
|
FOLR1
|
folate receptor 1 (adult)
|
1.613
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
1.612
|
|
BGLAP
|
bone gamma-carboxyglutamate (gla) protein
|
1.604
|
|
DUOX1
|
dual oxidase 1
|
1.603
|
|
CALML4
|
calmodulin-like 4
|
1.602
|
|
CALML6
|
calmodulin-like 6
|
1.602
|
|
CALML5
|
calmodulin-like 5
|
1.599
|
|
CALML3
|
calmodulin-like 3
|
1.599
|
|
SMPD1
|
sphingomyelin phosphodiesterase 1, acid lysosomal
|
1.596
|
|
SHMT2
|
serine hydroxymethyltransferase 2 (mitochondrial)
|
1.594
|
|
MAPK3
|
mitogen-activated protein kinase 3
|
1.594
|
|
NOX1
|
NADPH oxidase 1
|
1.589
|
|
CALM3
|
calmodulin 3 (phosphorylase kinase, delta)
|
1.588
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
1.581
|
|
CDK5
|
cyclin-dependent kinase 5
|
1.576
|
|
DNAH8
|
dynein, axonemal, heavy chain 8
|
1.569
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
1.564
|
|
FHDC1
|
FH2 domain containing 1
|
1.563
|
|
BAX
|
BCL2-associated X protein
|
1.562
|
|
KEAP1
|
kelch-like ECH-associated protein 1
|
1.546
|
|
TXNIP
|
thioredoxin interacting protein
|
1.541
|
|
GRIN1
|
glutamate receptor, ionotropic, N-methyl D-aspartate 1
|
1.536
|
|
LOX
|
lysyl oxidase
|
1.534
|
|
IL17A
|
interleukin 17A
|
1.533
|
|
GSK3B
|
glycogen synthase kinase 3 beta
|
1.533
|
|
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
1.53
|
|
NPHS2
|
nephrosis 2, idiopathic, steroid-resistant (podocin)
|
1.529
|
|
TP53
|
tumor protein p53
|
1.528
|
|
NCF2
|
neutrophil cytosolic factor 2
|
1.524
|
|
DUOX2
|
dual oxidase 2
|
1.522
|
|
OCLN
|
occludin
|
1.52
|
|
MPO
|
myeloperoxidase
|
1.519
|
|
ACHE
|
acetylcholinesterase (Yt blood group)
|
1.519
|
|
CDH5
|
cadherin 5, type 2 (vascular endothelium)
|
1.516
|
|
NPHS1
|
nephrosis 1, congenital, Finnish type (nephrin)
|
1.514
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
1.51
|
|
DAO
|
D-amino-acid oxidase
|
1.51
|
|
HP
|
haptoglobin
|
1.502
|
|
AMN
|
amnion associated transmembrane protein
|
1.5
|
|
CD4
|
CD4 molecule
|
1.497
|
|
CLDN5
|
claudin 5
|
1.496
|
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase
|
1.495
|
|
MTHFS
|
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
|
1.495
|
|
TTR
|
transthyretin
|
1.494
|
|
GRIN2A
|
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
|
1.492
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
1.49
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
1.489
|
|
GJA5
|
gap junction protein, alpha 5, 40kDa
|
1.488
|
|
JAK2
|
Janus kinase 2
|
1.487
|
|
CYP2E1
|
cytochrome P450, family 2, subfamily E, polypeptide 1
|
1.486
|
|
ATP4A
|
ATPase, H+/K+ exchanging, alpha polypeptide
|
1.484
|
|
CPB2
|
carboxypeptidase B2 (plasma)
|
1.482
|
|
ATP12A
|
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
|
1.474
|
|
HMGB1
|
high mobility group box 1
|
1.471
|
|
NPPB
|
natriuretic peptide B
|
1.461
|
|
ANXA2
|
annexin A2
|
1.461
|
|
GAMT
|
guanidinoacetate N-methyltransferase
|
1.459
|
|
EIF2AK3
|
eukaryotic translation initiation factor 2-alpha kinase 3
|
1.458
|
|
CASP9
|
caspase 9, apoptosis-related cysteine peptidase
|
1.458
|
|
TST
|
thiosulfate sulfurtransferase (rhodanese)
|
1.458
|
|
FN1
|
fibronectin 1
|
1.455
|
|
MAT2A
|
methionine adenosyltransferase II, alpha
|
1.454
|
|
CDO1
|
cysteine dioxygenase type 1
|
1.454
|
|
RETN
|
resistin
|
1.452
|
|
CBLIF
|
cobalamin binding intrinsic factor
|
1.446
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
1.446
|
|
HDAC9
|
histone deacetylase 9
|
1.443
|
|
LPL
|
lipoprotein lipase
|
1.438
|
|
ADAMTS13
|
ADAM metallopeptidase with thrombospondin type 1 motif, 13
|
1.438
|
|
H3C13
|
H3 clustered histone 13
|
1.437
|
|
CKB
|
creatine kinase, brain
|
1.437
|
|
CKM
|
creatine kinase, muscle
|
1.435
|
|
RETNLB
|
resistin like beta
|
1.433
|
|
H3-5
|
H3.5 histone
|
1.433
|
|
CKMT2
|
creatine kinase, mitochondrial 2 (sarcomeric)
|
1.432
|
|
H3-4
|
H3.4 histone, cluster member
|
1.432
|
|
H3C12
|
H3 clustered histone 12
|
1.429
|
|
FOLR2
|
folate receptor 2 (fetal)
|
1.427
|
|
CKMT1B
|
creatine kinase, mitochondrial 1B
|
1.426
|
|
PRKACG
|
protein kinase, cAMP-dependent, catalytic, gamma
|
1.425
|
|
PRKACA
|
protein kinase, cAMP-dependent, catalytic, alpha
|
1.424
|
|
F9
|
coagulation factor IX
|
1.423
|
|
H3-3B
|
H3.3 histone B
|
1.422
|
|
ATF4
|
activating transcription factor 4
|
1.419
|
|
NOS2
|
nitric oxide synthase 2, inducible
|
1.416
|
|
SIRT3
|
sirtuin 3
|
1.414
|
|
GRIN2B
|
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
|
1.411
|
|
MAP3K5
|
mitogen-activated protein kinase kinase kinase 5
|
1.41
|
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta
|
1.41
|
|
BCHE
|
butyrylcholinesterase
|
1.408
|
|
SOD2
|
superoxide dismutase 2, mitochondrial
|
1.407
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
1.406
|
|
CREB1
|
cAMP responsive element binding protein 1
|
1.405
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
1.402
|
|
PECAM1
|
platelet/endothelial cell adhesion molecule 1
|
1.393
|
|
SOD1
|
superoxide dismutase 1, soluble
|
1.393
|
|
TNFRSF11B
|
tumor necrosis factor receptor superfamily, member 11b
|
1.392
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
1.391
|
|
NOX5
|
NADPH oxidase, EF-hand calcium binding domain 5
|
1.385
|
|
GJA1
|
gap junction protein, alpha 1, 43kDa
|
1.378
|
|
KDR
|
kinase insert domain receptor
|
1.375
|
|
NGF
|
nerve growth factor (beta polypeptide)
|
1.375
|
|
CD40LG
|
CD40 ligand
|
1.375
|
|
INSR
|
insulin receptor
|
1.371
|
|
TJP1
|
tight junction protein 1
|
1.369
|
|
GCG
|
glucagon
|
1.36
|
|
GSDMD
|
gasdermin D
|
1.359
|
|
F11
|
coagulation factor XI
|
1.355
|
|
CAV1
|
caveolin 1, caveolae protein, 22kDa
|
1.353
|
|
PIK3C3
|
phosphatidylinositol 3-kinase, catalytic subunit type 3
|
1.349
|
|
PKM
|
pyruvate kinase, muscle
|
1.349
|
|
PGF
|
placental growth factor
|
1.348
|
|
MYH14
|
myosin, heavy chain 14, non-muscle
|
1.347
|
|
ETHE1
|
ethylmalonic encephalopathy 1
|
1.346
|
|
UCP2
|
uncoupling protein 2 (mitochondrial, proton carrier)
|
1.346
|
|
MSRB2
|
methionine sulfoxide reductase B2
|
1.345
|
|
PPP2CA
|
protein phosphatase 2, catalytic subunit, alpha isozyme
|
1.34
|
|
AGER
|
advanced glycosylation end product-specific receptor
|
1.339
|
|
FBN1
|
fibrillin 1
|
1.339
|
|
IRS1
|
insulin receptor substrate 1
|
1.335
|
|
SLC2A4
|
solute carrier family 2 (facilitated glucose transporter), member 4
|
1.331
|
|
IL4
|
interleukin 4
|
1.331
|
|
AHCYL1
|
adenosylhomocysteinase-like 1
|
1.33
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
1.33
|
|
PPME1
|
protein phosphatase methylesterase 1
|
1.327
|
|
MAOB
|
monoamine oxidase B
|
1.324
|
|
NOTCH3
|
notch 3
|
1.322
|
|
ARG1
|
arginase 1
|
1.321
|
|
ABCG1
|
ATP-binding cassette, sub-family G (WHITE), member 1
|
1.319
|
|
GCLC
|
glutamate-cysteine ligase, catalytic subunit
|
1.316
|
|
SPP1
|
secreted phosphoprotein 1
|
1.315
|
|
DLG4
|
discs, large homolog 4 (Drosophila)
|
1.313
|
|
TLR2
|
toll-like receptor 2
|
1.313
|
|
MGP
|
matrix Gla protein
|
1.312
|
|
FOLR3
|
folate receptor 3 (gamma)
|
1.31
|
|
HAMP
|
hepcidin antimicrobial peptide
|
1.306
|
|
IL2
|
interleukin 2
|
1.306
|
|
CLU
|
clusterin
|
1.3
|
|
ITGB3
|
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
|
1.299
|
|
FOXO1
|
forkhead box O1
|
1.298
|
|
NPPA
|
natriuretic peptide A
|
1.296
|
|
BECN1
|
beclin 1, autophagy related
|
1.289
|
|
EIF2AK2
|
eukaryotic translation initiation factor 2-alpha kinase 2
|
1.289
|
|
APOC3
|
apolipoprotein C-III
|
1.287
|
|
MFN2
|
mitofusin 2
|
1.286
|
|
EPHX2
|
epoxide hydrolase 2, cytoplasmic
|
1.284
|
|
SOD3
|
superoxide dismutase 3, extracellular
|
1.284
|
|
FGF2
|
fibroblast growth factor 2 (basic)
|
1.282
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
1.278
|
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1
|
1.277
|
|
PDE5A
|
phosphodiesterase 5A, cGMP-specific
|
1.276
|
|
KLF2
|
Kruppel-like factor 2
|
1.273
|
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa
|
1.271
|
|
PF4
|
platelet factor 4
|
1.27
|
|
SP1
|
Sp1 transcription factor
|
1.27
|
|
KL
|
klotho
|
1.27
|
|
SERPIND1
|
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
|
1.268
|
|
TET2
|
tet methylcytosine dioxygenase 2
|
1.267
|
|
GCH1
|
GTP cyclohydrolase 1
|
1.266
|
|
MT1E
|
metallothionein 1E
|
1.262
|
|
PLA2G7
|
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
|
1.262
|
|
PCSK9
|
proprotein convertase subtilisin/kexin type 9
|
1.261
|
|
TNFSF11
|
tumor necrosis factor (ligand) superfamily, member 11
|
1.259
|
|
FOLH1
|
folate hydrolase (prostate-specific membrane antigen) 1
|
1.259
|
|
PRKN
|
parkin RBR E3 ubiquitin protein ligase
|
1.256
|
|
CETP
|
cholesteryl ester transfer protein, plasma
|
1.256
|
|
CCL5
|
chemokine (C-C motif) ligand 5
|
1.255
|
|
TXN2
|
thioredoxin 2
|
1.252
|
|
ENHO
|
energy homeostasis associated
|
1.249
|
|
ESR1
|
estrogen receptor 1
|
1.245
|
|
HDAC1
|
histone deacetylase 1
|
1.245
|
|
XPR1
|
xenotropic and polytropic retrovirus receptor 1
|
1.242
|
|
PSEN2
|
presenilin 2
|
1.242
|
|
LCAT
|
lecithin-cholesterol acyltransferase
|
1.242
|
|
CP
|
ceruloplasmin (ferroxidase)
|
1.239
|
|
FGF21
|
fibroblast growth factor 21
|
1.239
|
|
MTHFD1L
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
|
1.236
|
|
TET1
|
tet methylcytosine dioxygenase 1
|
1.235
|
|
GPX4
|
glutathione peroxidase 4
|
1.234
|
|
PON2
|
paraoxonase 2
|
1.234
|
|
APOA4
|
apolipoprotein A-IV
|
1.233
|
|
CAPN2
|
calpain 2, (m/II) large subunit
|
1.228
|
|
FGF23
|
fibroblast growth factor 23
|
1.228
|
|
FLT1
|
fms-related tyrosine kinase 1
|
1.227
|
|
MB
|
myoglobin
|
1.226
|
|
TIMP3
|
TIMP metallopeptidase inhibitor 3
|
1.221
|
|
GHRL
|
ghrelin/obestatin prepropeptide
|
1.22
|
|
CCN2
|
cellular communication network factor 2
|
1.219
|
|
EIF2S1
|
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
|
1.216
|
|
ARG2
|
arginase 2
|
1.213
|
|
AHR
|
aryl hydrocarbon receptor
|
1.213
|
|
CCNA1
|
cyclin A1
|
1.213
|
|
ANXA5
|
annexin A5
|
1.21
|
|
IDE
|
insulin-degrading enzyme
|
1.207
|
|
NAMPT
|
nicotinamide phosphoribosyltransferase
|
1.207
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
1.205
|
|
GPT2
|
glutamic pyruvate transaminase (alanine aminotransferase) 2
|
1.202
|
|
PINK1
|
PTEN induced putative kinase 1
|
1.201
|
|
S100B
|
S100 calcium binding protein B
|
1.201
|
|
SUOX
|
sulfite oxidase
|
1.198
|
|
TFAM
|
transcription factor A, mitochondrial
|
1.198
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
1.193
|
|
HDAC2
|
histone deacetylase 2
|
1.192
|
|
NSUN2
|
NOP2/Sun RNA methyltransferase family, member 2
|
1.191
|
|
MMP3
|
matrix metallopeptidase 3
|
1.191
|
|
DNAJC10
|
DnaJ (Hsp40) homolog, subfamily C, member 10
|
1.189
|
|
DNM1L
|
dynamin 1-like
|
1.187
|
|
NR1H4
|
nuclear receptor subfamily 1, group H, member 4
|
1.175
|
|
SMPDL3B
|
sphingomyelin phosphodiesterase, acid-like 3B
|
1.173
|
|
IGF2
|
insulin-like growth factor 2
|
1.173
|
|
CD8A
|
CD8a molecule
|
1.172
|
|
CSN3
|
casein kappa
|
1.169
|
|
PINX1
|
PIN2/TERF1 interacting, telomerase inhibitor 1
|
1.168
|
|
KDM6B
|
lysine (K)-specific demethylase 6B
|
1.167
|
|
MECP2
|
methyl CpG binding protein 2
|
1.166
|
|
KLF4
|
Kruppel-like factor 4 (gut)
|
1.164
|
|
PROCR
|
protein C receptor, endothelial
|
1.163
|
|
SLC1A1
|
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
|
1.162
|
|
CASP8
|
caspase 8, apoptosis-related cysteine peptidase
|
1.161
|
|
ADD1
|
adducin 1 (alpha)
|
1.16
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
1.157
|
|
RHOA
|
ras homolog family member A
|
1.156
|
|
SLC25A32
|
solute carrier family 25 (mitochondrial folate carrier), member 32
|
1.155
|
|
ITGA2B
|
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
|
1.154
|
|
LCN2
|
lipocalin 2
|
1.153
|
|
FOXP3
|
forkhead box P3
|
1.153
|
|
NEFL
|
neurofilament, light polypeptide
|
1.152
|
|
GRM5
|
glutamate receptor, metabotropic 5
|
1.151
|
|
CARS2
|
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
|
1.149
|
|
PRL
|
prolactin
|
1.147
|
|
CCNA2
|
cyclin A2
|
1.147
|
|
PDXK
|
pyridoxal (pyridoxine, vitamin B6) kinase
|
1.147
|
|
SAA1
|
serum amyloid A1
|
1.145
|
|
FOXO3
|
forkhead box O3
|
1.141
|
|
HMOX2
|
heme oxygenase 2
|
1.14
|
|
MAT2B
|
methionine adenosyltransferase II, beta
|
1.139
|
|
SAA2
|
serum amyloid A2
|
1.139
|
|
C1ORF167
|
chromosome 1 open reading frame 167
|
1.137
|
|
SERPINF2
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
|
1.137
|
|
SLC2A1
|
solute carrier family 2 (facilitated glucose transporter), member 1
|
1.135
|
|
CAST
|
calpastatin
|
1.133
|
|
CCR2
|
chemokine (C-C motif) receptor 2
|
1.133
|
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
1.132
|
|
GGH
|
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
|
1.13
|
|
NFE2
|
nuclear factor, erythroid 2
|
1.129
|
|
CYP2J2
|
cytochrome P450, family 2, subfamily J, polypeptide 2
|
1.129
|
|
MAOA
|
monoamine oxidase A
|
1.129
|
|
PRDX2
|
peroxiredoxin 2
|
1.127
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
1.127
|
|
AIF1
|
allograft inflammatory factor 1
|
1.127
|
|
ACOX1
|
acyl-CoA oxidase 1, palmitoyl
|
1.125
|
|
PPIG
|
peptidylprolyl isomerase G (cyclophilin G)
|
1.124
|
|
PON3
|
paraoxonase 3
|
1.124
|
|
MMEL1
|
membrane metallo-endopeptidase-like 1
|
1.123
|
|
PRDX1
|
peroxiredoxin 1
|
1.123
|
|
EGF
|
epidermal growth factor
|
1.12
|
|
RUNX2
|
runt-related transcription factor 2
|
1.119
|
|
B2M
|
beta-2-microglobulin
|
1.117
|
|
LRP2
|
low density lipoprotein receptor-related protein 2
|
1.116
|
|
GC
|
group-specific component (vitamin D binding protein)
|
1.115
|
|
PLLP
|
plasmolipin
|
1.115
|
|
MBP
|
myelin basic protein
|
1.115
|
|
ALDH2
|
aldehyde dehydrogenase 2 family (mitochondrial)
|
1.115
|
|
ITGAM
|
integrin, alpha M (complement component 3 receptor 3 subunit)
|
1.113
|
|
TNNI3
|
troponin I type 3 (cardiac)
|
1.113
|
|
CSAD
|
cysteine sulfinic acid decarboxylase
|
1.113
|
|
MAPK8
|
mitogen-activated protein kinase 8
|
1.111
|
|
NCF4
|
neutrophil cytosolic factor 4, 40kDa
|
1.109
|
|
PARK7
|
parkinson protein 7
|
1.106
|
|
ST20-MTHFS
|
ST20-MTHFS readthrough
|
1.106
|
|
PAH
|
phenylalanine hydroxylase
|
1.106
|
|
FGA
|
fibrinogen alpha chain
|
1.105
|
|
AIM2
|
absent in melanoma 2
|
1.104
|
|
AKR1B1
|
aldo-keto reductase family 1, member B1 (aldose reductase)
|
1.104
|
|
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
|
1.103
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
1.103
|
|
PTEN
|
phosphatase and tensin homolog
|
1.102
|
|
MYOCD
|
myocardin
|
1.1
|
|
TXNRD1
|
thioredoxin reductase 1
|
1.1
|
|
PPBP
|
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
|
1.098
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
1.098
|
|
IZUMO1R
|
IZUMO1 receptor, JUNO
|
1.095
|
|
GFAP
|
glial fibrillary acidic protein
|
1.094
|
|
SYN1
|
synapsin I
|
1.093
|
|
TNFRSF1A
|
tumor necrosis factor receptor superfamily, member 1A
|
1.092
|
|
GJA4
|
gap junction protein, alpha 4, 37kDa
|
1.091
|
|
DPP4
|
dipeptidyl-peptidase 4
|
1.09
|
|
SPTLC3
|
serine palmitoyltransferase, long chain base subunit 3
|
1.09
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
1.087
|
|
GATM
|
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
|
1.084
|
|
PRTN3
|
proteinase 3
|
1.083
|
|
NRF1
|
nuclear respiratory factor 1
|
1.083
|
|
TRDMT1
|
tRNA aspartic acid methyltransferase 1
|
1.082
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
1.082
|
|
CTSS
|
cathepsin S
|
1.082
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
1.081
|
|
FTO
|
fat mass and obesity associated
|
1.081
|
|
SERPINA1
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
|
1.079
|
|
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
|
1.078
|
|
EDNRB
|
endothelin receptor type B
|
1.078
|
|
LIPC
|
lipase, hepatic
|
1.078
|
|
PPARD
|
peroxisome proliferator-activated receptor delta
|
1.076
|
|
CARS1
|
cysteinyl-tRNA synthetase 1
|
1.074
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
1.074
|
|
PROC
|
protein C (inactivator of coagulation factors Va and VIIIa)
|
1.073
|
|
TH
|
tyrosine hydroxylase
|
1.072
|
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
1.07
|
|
AHSG
|
alpha-2-HS-glycoprotein
|
1.07
|
|
IL13
|
interleukin 13
|
1.07
|
|
NOX3
|
NADPH oxidase 3
|
1.067
|
|
ATG7
|
autophagy related 7
|
1.067
|
|
CYP7A1
|
cytochrome P450, family 7, subfamily A, polypeptide 1
|
1.066
|
|
HDAC3
|
histone deacetylase 3
|
1.065
|
|
CYP27A1
|
cytochrome P450, family 27, subfamily A, polypeptide 1
|
1.062
|
|
AGXT2
|
alanine--glyoxylate aminotransferase 2
|
1.062
|
|
ATP5F1A
|
ATP synthase F1 subunit alpha
|
1.059
|
|
EHMT2
|
euchromatic histone-lysine N-methyltransferase 2
|
1.059
|
|
APOA2
|
apolipoprotein A-II
|
1.058
|
|
ATF3
|
activating transcription factor 3
|
1.054
|
|
TFEB
|
transcription factor EB
|
1.054
|
|
SMAD3
|
SMAD family member 3
|
1.053
|
|
GSTM1
|
glutathione S-transferase mu 1
|
1.052
|
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
1.052
|
|
FGF9
|
fibroblast growth factor 9
|
1.048
|
|
NR1D1
|
nuclear receptor subfamily 1, group D, member 1
|
1.045
|
|
ACE2
|
angiotensin I converting enzyme 2
|
1.044
|
|
FGF20
|
fibroblast growth factor 20
|
1.044
|
|
LEPR
|
leptin receptor
|
1.044
|
|
MMP14
|
matrix metallopeptidase 14 (membrane-inserted)
|
1.043
|
|
HTR2A
|
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
|
1.043
|
|
MTTP
|
microsomal triglyceride transfer protein
|
1.043
|
|
CHAT
|
choline O-acetyltransferase
|
1.042
|
|
PTPN1
|
protein tyrosine phosphatase, non-receptor type 1
|
1.04
|
|
TAGLN
|
transgelin
|
1.039
|
|
FGF18
|
fibroblast growth factor 18
|
1.039
|
|
SLC1A2
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2
|
1.038
|
|
GLOD4
|
glyoxalase domain containing 4
|
1.037
|
|
FGF16
|
fibroblast growth factor 16
|
1.037
|
|
RNF213
|
ring finger protein 213
|
1.033
|
|
FGF3
|
fibroblast growth factor 3
|
1.033
|
|
FGF22
|
fibroblast growth factor 22
|
1.029
|
|
FGF5
|
fibroblast growth factor 5
|
1.029
|
|
BMP2
|
bone morphogenetic protein 2
|
1.029
|
|
AVP
|
arginine vasopressin
|
1.029
|
|
FGF6
|
fibroblast growth factor 6
|
1.027
|
|
CYP2C9
|
cytochrome P450, family 2, subfamily C, polypeptide 9
|
1.027
|
|
SLC25A26
|
solute carrier family 25 (S-adenosylmethionine carrier), member 26
|
1.027
|
|
FGF8
|
fibroblast growth factor 8 (androgen-induced)
|
1.024
|
|
FGF4
|
fibroblast growth factor 4
|
1.023
|
|
LGALS3
|
lectin, galactoside-binding, soluble, 3
|
1.022
|
|
FGF10
|
fibroblast growth factor 10
|
1.019
|
|
VAV2
|
vav 2 guanine nucleotide exchange factor
|
1.019
|
|
SOAT2
|
sterol O-acyltransferase 2
|
1.019
|
|
COL4A1
|
collagen, type IV, alpha 1
|
1.019
|
|
ITPR1
|
inositol 1,4,5-trisphosphate receptor, type 1
|
1.017
|
|
ADORA2A
|
adenosine A2a receptor
|
1.017
|
|
CFB
|
complement factor B
|
1.017
|
|
NLRP1
|
NLR family, pyrin domain containing 1
|
1.016
|
|
POMC
|
proopiomelanocortin
|
1.016
|
|
SMAD2
|
SMAD family member 2
|
1.016
|
|
COX4I1
|
cytochrome c oxidase subunit IV isoform 1
|
1.015
|
|
ENG
|
endoglin
|
1.015
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
1.014
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
1.013
|
|
DNTT
|
DNA nucleotidylexotransferase
|
1.013
|
|
CD68
|
CD68 molecule
|
1.012
|
|
FGF17
|
fibroblast growth factor 17
|
1.012
|
|
KYAT1
|
kynurenine aminotransferase 1
|
1.011
|
|
FASN
|
fatty acid synthase
|
1.01
|
|
HSPA4
|
heat shock 70kDa protein 4
|
1.01
|
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage)
|
1.01
|
|
MYD88
|
myeloid differentiation primary response 88
|
1.009
|
|
MMP1
|
matrix metallopeptidase 1
|
1.008
|
|
FGB
|
fibrinogen beta chain
|
1.008
|
|
SRF
|
serum response factor (c-fos serum response element-binding transcription factor)
|
1.007
|
|
MCEE
|
methylmalonyl CoA epimerase
|
1.007
|
|
APOA5
|
apolipoprotein A-V
|
1.006
|
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1
|
1.006
|
|
AS3MT
|
arsenite methyltransferase
|
1.005
|
|
F2R
|
coagulation factor II (thrombin) receptor
|
1.005
|
|
TKT
|
transketolase
|
1.005
|
|
H2AC20
|
H2A clustered histone 20
|
1.004
|
|
TKTL2
|
transketolase-like 2
|
1.003
|
|
NTRK2
|
neurotrophic tyrosine kinase, receptor, type 2
|
1.003
|
|
H2AC18
|
H2A clustered histone 18
|
1.002
|
|
IFNA1
|
interferon, alpha 1
|
1.001
|
