Hyperimmunoglobulinemia D periodic fever syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

108 genes co-occuring with the disease Hyperimmunoglobulinemia D periodic fever syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MVK mevalonate kinase 3.438
MEFV Mediterranean fever 2.74
NLRP3 NLR family, pyrin domain containing 3 2.442
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.306
NLRP12 NLR family, pyrin domain containing 12 2.231
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.178
IL1B interleukin 1, beta 2.11
NLRC4 NLR family, CARD domain containing 4 2.003
IL1RL2 interleukin 1 receptor-like 2 1.991
IL1RN interleukin 1 receptor antagonist 1.973
IL1A interleukin 1, alpha 1.931
IL36RN interleukin 36 receptor antagonist 1.93
LPIN2 lipin 2 1.887
CARD14 caspase recruitment domain family, member 14 1.877
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.854
WDR1 WD repeat domain 1 1.852
NOD2 nucleotide-binding oligomerization domain containing 2 1.851
PKN1 protein kinase N1 1.828
OTULIN OTU deubiquitinase with linear linkage specificity 1.822
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 1.786
IL18 interleukin 18 1.78
TNF tumor necrosis factor 1.757
ADA2 adenosine deaminase 2 1.684
NLRP1 NLR family, pyrin domain containing 1 1.666
PKN2 protein kinase N2 1.655
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.655
RNASEH2C ribonuclease H2, subunit C 1.65
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.642
IL1R1 interleukin 1 receptor, type I 1.628
UNC13D unc-13 homolog D (C. elegans) 1.58
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.563
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.541
IL1F10 interleukin 1 family, member 10 (theta) 1.538
AIM2 absent in melanoma 2 1.537
RNASEH2B ribonuclease H2, subunit B 1.53
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 1.522
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.505
IL6 interleukin 6 1.501
PMVK phosphomevalonate kinase 1.5
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.491
CRP C-reactive protein, pentraxin-related 1.49
STING1 stimulator of interferon response cGAMP interactor 1 1.487
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.475
IL18BP interleukin 18 binding protein 1.46
RNF31 ring finger protein 31 1.455
RHOA ras homolog family member A 1.454
SHARPIN SHANK-associated RH domain interactor 1.451
IL1RAP interleukin 1 receptor accessory protein 1.438
SAA2 serum amyloid A2 1.402
POMP proteasome maturation protein 1.4
SAA1 serum amyloid A1 1.397
ZNF318 zinc finger protein 318 1.38
IFNG interferon, gamma 1.354
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.333
SAMHD1 SAM domain and HD domain 1 1.314
FDPS farnesyl diphosphate synthase 1.297
STX11 syntaxin 11 1.295
RNASEH2A ribonuclease H2, subunit A 1.287
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 1.264
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.26
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.251
STAT1 signal transducer and activator of transcription 1, 91kDa 1.241
GSDMD gasdermin D 1.238
IL17A interleukin 17A 1.219
AICDA activation-induced cytidine deaminase 1.215
IL10 interleukin 10 1.211
SH2D1A SH2 domain containing 1A 1.202
ADAR adenosine deaminase, RNA-specific 1.191
IL36G interleukin 36, gamma 1.19
SAA2-SAA4 SAA2-SAA4 readthrough 1.189
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.186
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.178
MVD mevalonate (diphospho) decarboxylase 1.169
DNASE2 deoxyribonuclease II, lysosomal 1.163
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.163
IL37 interleukin 37 1.157
CD4 CD4 molecule 1.147
CARD8 caspase recruitment domain family, member 8 1.143
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.138
NLRP6 NLR family, pyrin domain containing 6 1.137
DOCK8 dedicator of cytokinesis 8 1.127
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 1.125
GZMM granzyme M (lymphocyte met-ase 1) 1.12
IFNB1 interferon, beta 1, fibroblast 1.112
SAA4 serum amyloid A4, constitutive 1.103
STXBP2 syntaxin binding protein 2 1.097
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.095
DCLRE1C DNA cross-link repair 1C 1.092
IRAK4 interleukin-1 receptor-associated kinase 4 1.085
CD40LG CD40 ligand 1.078
IL33 interleukin 33 1.076
CLEC7A C-type lectin domain family 7, member A 1.071
IFNA1 interferon, alpha 1 1.066
LYST lysosomal trafficking regulator 1.065
NLRP7 NLR family, pyrin domain containing 7 1.059
PRPF3 pre-mRNA processing factor 3 1.056
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.049
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.047
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.047
IFIH1 interferon induced with helicase C domain 1 1.039
DHDDS dehydrodolichyl diphosphate synthase 1.035
CGAS cyclic GMP-AMP synthase 1.023
CXCL8 chemokine (C-X-C motif) ligand 8 1.02
TLR4 toll-like receptor 4 1.016
IFT140 intraflagellar transport 140 1.013
ADA adenosine deaminase 1.01
IL2 interleukin 2 1.003
BAHD1 bromo adjacent homology domain containing 1 1.001