Hyperostosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A bone remodeling disease that results in an abnormal growth of located_in bone. (Human Disease Ontology, DOID_205)
External Link https://www.disgenet.org/browser/0/1/0/C0020492
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Genes

61 genes associated with the disease Hyperostosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALMS1 Alstrom syndrome protein 1
ALPL alkaline phosphatase, liver/bone/kidney
AMER1 APC membrane recruitment protein 1
ANXA5 annexin A5
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
BMPR1A bone morphogenetic protein receptor, type IA
CCL2 chemokine (C-C motif) ligand 2
CD38 CD38 molecule
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DMP1 dentin matrix acidic phosphoprotein 1
EBP emopamil binding protein (sterol isomerase)
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FGF23 fibroblast growth factor 23
FGFR3 fibroblast growth factor receptor 3
FLNA filamin A, alpha
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLI3 GLI family zinc finger 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
HHAT hedgehog acyltransferase
HLA-B major histocompatibility complex, class I, B
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
LEMD3 LEM domain containing 3
LEP leptin
LRP4 low density lipoprotein receptor-related protein 4
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
OSTM1 osteopetrosis associated transmembrane protein 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTEN phosphatase and tensin homolog
PTH parathyroid hormone
RPS19 ribosomal protein S19
RUNX2 runt-related transcription factor 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SFRP1 secreted frizzled-related protein 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOST sclerostin
SPP1 secreted phosphoprotein 1
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPH1 tryptophan hydroxylase 1
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1