Hyperparathyroidism Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A parathyroid gland disease characterized by an overactivity of the parathyroid glands, leading to an excess of parathyroid hormone in the body. (Human Disease Ontology, DOID_13543)
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Genes

545 genes co-occuring with the disease Hyperparathyroidism in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PTH parathyroid hormone 4.0
CASR calcium-sensing receptor 3.852
FGF23 fibroblast growth factor 23 3.813
MEN1 multiple endocrine neoplasia I 3.656
CDC73 cell division cycle 73 3.572
BGLAP bone gamma-carboxyglutamate (gla) protein 3.318
KL klotho 3.237
PTHLH parathyroid hormone-like hormone 3.183
ALB albumin 3.081
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 3.017
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.996
RET ret proto-oncogene 2.992
SOST sclerostin 2.964
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.9
GCM2 glial cells missing homolog 2 (Drosophila) 2.896
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.881
GC group-specific component (vitamin D binding protein) 2.863
EPO erythropoietin 2.81
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.799
PHEX phosphate regulating endopeptidase homolog, X-linked 2.79
PTH1R parathyroid hormone 1 receptor 2.782
REN renin 2.778
ACP5 acid phosphatase 5, tartrate resistant 2.744
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 2.743
GAST gastrin 2.72
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.592
EMP1 epithelial membrane protein 1 2.587
INS insulin 2.579
MGP matrix Gla protein 2.569
IGF1 insulin-like growth factor 1 (somatomedin C) 2.54
AHSG alpha-2-HS-glycoprotein 2.514
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.51
CRP C-reactive protein, pentraxin-related 2.507
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.504
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.471
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.457
RUNX2 runt-related transcription factor 2 2.45
PRL prolactin 2.445
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.444
SPP1 secreted phosphoprotein 1 2.386
DMP1 dentin matrix acidic phosphoprotein 1 2.385
ALPL alkaline phosphatase, liver/bone/kidney 2.383
ACE angiotensin I converting enzyme 2.367
IL6 interleukin 6 2.357
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.351
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.351
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.348
POMC proopiomelanocortin 2.341
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2.325
CHGA chromogranin A 2.317
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.234
MEPE matrix extracellular phosphoglycoprotein 2.23
SST somatostatin 2.217
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.216
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.209
SP7 Sp7 transcription factor 2.196
TNF tumor necrosis factor 2.185
FGFR1 fibroblast growth factor receptor 1 2.166
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.165
FGF7 fibroblast growth factor 7 2.15
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.15
S100G S100 calcium binding protein G 2.146
FGF3 fibroblast growth factor 3 2.144
FGF16 fibroblast growth factor 16 2.133
GNAS GNAS complex locus 2.132
FGF22 fibroblast growth factor 22 2.131
FGF17 fibroblast growth factor 17 2.13
CTSK cathepsin K 2.13
FGF6 fibroblast growth factor 6 2.129
FGF20 fibroblast growth factor 20 2.128
FGF18 fibroblast growth factor 18 2.128
FGF9 fibroblast growth factor 9 2.126
FGF5 fibroblast growth factor 5 2.125
LEP leptin 2.118
FGF8 fibroblast growth factor 8 (androgen-induced) 2.117
GCG glucagon 2.116
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.115
FGF4 fibroblast growth factor 4 2.112
FGF10 fibroblast growth factor 10 2.111
LRP5 low density lipoprotein receptor-related protein 5 2.11
ESR1 estrogen receptor 1 2.096
CCND1 cyclin D1 2.086
PPY pancreatic polypeptide 2.086
SCT secretin 2.076
B2M beta-2-microglobulin 2.071
IL1B interleukin 1, beta 2.057
TG thyroglobulin 2.055
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.054
CLDN16 claudin 16 2.051
BMP2 bone morphogenetic protein 2 2.044
COL1A2 collagen, type I, alpha 2 2.041
APOM apolipoprotein M 2.04
LRP2 low density lipoprotein receptor-related protein 2 2.017
TGFB1 transforming growth factor, beta 1 2.012
NR0B2 nuclear receptor subfamily 0, group B, member 2 2.004
GHRH growth hormone releasing hormone 1.991
NF1 neurofibromin 1 1.98
PTH2R parathyroid hormone 2 receptor 1.978
CST3 cystatin C 1.962
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.957
TMEM127 transmembrane protein 127 1.954
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.953
ALPG alkaline phosphatase, germ cell 1.951
IL1A interleukin 1, alpha 1.947
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.919
ALPI alkaline phosphatase, intestinal 1.917
IBSP integrin-binding sialoprotein 1.912
HAMP hepcidin antimicrobial peptide 1.911
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.904
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.902
ADIPOQ adiponectin, C1Q and collagen domain containing 1.901
CLDN14 claudin 14 1.898
ALPP alkaline phosphatase, placental 1.894
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.879
DNAH8 dynein, axonemal, heavy chain 8 1.873
VIP vasoactive intestinal peptide 1.873
SYP synaptophysin 1.863
WNT10B wingless-type MMTV integration site family, member 10B 1.861
CLDN19 claudin 19 1.859
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.846
ANKH ANKH inorganic pyrophosphate transport regulator 1.84
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.819
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.807
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.788
FGFR4 fibroblast growth factor receptor 4 1.787
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.784
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.783
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.778
SH3BP2 SH3-domain binding protein 2 1.774
MSX2 msh homeobox 2 1.773
AVP arginine vasopressin 1.765
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.76
PTH2 parathyroid hormone 2 1.758
CALB1 calbindin 1, 28kDa 1.755
TRPM6 transient receptor potential cation channel, subfamily M, member 6 1.744
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.743
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.739
NPPB natriuretic peptide B 1.735
FAM20C family with sequence similarity 20, member C 1.731
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.723
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.719
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.71
SFRP4 secreted frizzled-related protein 4 1.71
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.699
SHBG sex hormone-binding globulin 1.697
SDHAF2 succinate dehydrogenase complex assembly factor 2 1.696
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.694
COL1A1 collagen, type I, alpha 1 1.689
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.676
FNDC5 fibronectin type III domain containing 5 1.669
JUND jun D proto-oncogene 1.668
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.662
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.66
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.657
BMP7 bone morphogenetic protein 7 1.654
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.653
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.651
PRUNE2 prune homolog 2 (Drosophila) 1.649
NPPA natriuretic peptide A 1.646
IFNG interferon, gamma 1.642
AIP aryl hydrocarbon receptor interacting protein 1.642
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.641
CD4 CD4 molecule 1.639
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.636
CLCN5 chloride channel, voltage-sensitive 5 1.631
TP53 tumor protein p53 1.631
CSH2 chorionic somatomammotropin hormone 2 1.624
HRH2 histamine receptor H2 1.624
IL17A interleukin 17A 1.614
TGFA transforming growth factor, alpha 1.605
FDPS farnesyl diphosphate synthase 1.605
IL10 interleukin 10 1.604
ADCK1 aarF domain containing kinase 1 1.599
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.594
GHRL ghrelin/obestatin prepropeptide 1.586
MSTN myostatin 1.583
STX16 syntaxin 16 1.581
SPINK1 serine peptidase inhibitor, Kazal type 1 1.578
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.576
UMOD uromodulin 1.575
GH1 growth hormone 1 1.571
PPARG peroxisome proliferator-activated receptor gamma 1.568
PXDN peroxidasin 1.566
PXDNL peroxidasin-like 1.564
TCHP trichoplein, keratin filament binding 1.554
MAPK3 mitogen-activated protein kinase 3 1.554
EDN1 endothelin 1 1.54
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.536
LRP6 low density lipoprotein receptor-related protein 6 1.535
IGFBP3 insulin-like growth factor binding protein 3 1.529
PHOSPHO1 phosphatase, orphan 1 1.526
TTR transthyretin 1.525
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.524
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.523
CCL2 chemokine (C-C motif) ligand 2 1.515
TGM2 transglutaminase 2 1.498
GPR101 G protein-coupled receptor 101 1.497
LGALS3 lectin, galactoside-binding, soluble, 3 1.495
UCMA upper zone of growth plate and cartilage matrix associated 1.495
EGLN1 egl-9 family hypoxia-inducible factor 1 1.489
CKM creatine kinase, muscle 1.488
ENO2 enolase 2 (gamma, neuronal) 1.486
ELN elastin 1.485
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.484
CTRC chymotrypsin C (caldecrin) 1.483
CKB creatine kinase, brain 1.483
GDNF glial cell derived neurotrophic factor 1.483
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.48
CKMT1B creatine kinase, mitochondrial 1B 1.479
ZFX zinc finger protein, X-linked 1.478
SSTR2 somatostatin receptor 2 1.476
PCNA proliferating cell nuclear antigen 1.475
GH2 growth hormone 2 1.473
TPO thyroid peroxidase 1.473
AQP2 aquaporin 2 (collecting duct) 1.473
FOS FBJ murine osteosarcoma viral oncogene homolog 1.468
SDF4 stromal cell derived factor 4 1.467
FXYD2 FXYD domain containing ion transport regulator 2 1.465
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.464
F2 coagulation factor II (thrombin) 1.46
FGFR3 fibroblast growth factor receptor 3 1.457
HNF1B HNF1 homeobox B 1.456
CLCN7 chloride channel, voltage-sensitive 7 1.452
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.452
FN1 fibronectin 1 1.451
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.451
CSF1 colony stimulating factor 1 (macrophage) 1.45
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.444
FGF2 fibroblast growth factor 2 (basic) 1.441
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.44
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.439
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.439
CXCL8 chemokine (C-X-C motif) ligand 8 1.436
CLCNKB chloride channel, voltage-sensitive Kb 1.436
PYY peptide YY 1.435
LDLR low density lipoprotein receptor 1.432
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.432
ACTB actin, beta 1.432
CALCR calcitonin receptor 1.428
LCN2 lipocalin 2 1.427
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.423
IGF2 insulin-like growth factor 2 1.423
GHR growth hormone receptor 1.42
CD8A CD8a molecule 1.416
CDKN3 cyclin-dependent kinase inhibitor 3 1.414
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.409
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.409
IL11 interleukin 11 1.408
IL2 interleukin 2 1.407
NCAM1 neural cell adhesion molecule 1 1.402
BMP4 bone morphogenetic protein 4 1.399
DHCR7 7-dehydrocholesterol reductase 1.398
NOMO3 NODAL modulator 3 1.395
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.395
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.393
NOMO2 NODAL modulator 2 1.393
WNK4 WNK lysine deficient protein kinase 4 1.39
MMP9 matrix metallopeptidase 9 1.386
NOMO1 NODAL modulator 1 1.383
APOE apolipoprotein E 1.382
IL4 interleukin 4 1.381
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.379
GATA3 GATA binding protein 3 1.378
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.377
NOS3 nitric oxide synthase 3 (endothelial cell) 1.376
JUN jun proto-oncogene 1.374
CD34 CD34 molecule 1.373
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.372
BSND barttin CLCNK-type chloride channel accessory beta subunit 1.371
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.365
NKX2-1 NK2 homeobox 1 1.364
EGLN3 egl-9 family hypoxia-inducible factor 3 1.362
GGCX gamma-glutamyl carboxylase 1.36
INSR insulin receptor 1.36
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.359
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.359
AGXT alanine-glyoxylate aminotransferase 1.358
AGTR1 angiotensin II receptor, type 1 1.355
EGLN2 egl-9 family hypoxia-inducible factor 2 1.355
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.353
FGF13 fibroblast growth factor 13 1.349
MAX MYC associated factor X 1.349
TRH thyrotropin-releasing hormone 1.343
CREB1 cAMP responsive element binding protein 1 1.343
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.338
LPL lipoprotein lipase 1.338
PAX8 paired box 8 1.337
CALML6 calmodulin-like 6 1.336
CALML4 calmodulin-like 4 1.336
CALML3 calmodulin-like 3 1.334
GSK3B glycogen synthase kinase 3 beta 1.334
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.334
CALML5 calmodulin-like 5 1.333
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 1.333
EGFR epidermal growth factor receptor 1.332
RGS14 regulator of G-protein signaling 14 1.331
XDH xanthine dehydrogenase 1.327
PRSS1 protease, serine, 1 (trypsin 1) 1.327
APOB apolipoprotein B 1.326
GLP1R glucagon-like peptide 1 receptor 1.324
CAMP cathelicidin antimicrobial peptide 1.323
ARRB2 arrestin, beta 2 1.319
CRH corticotropin releasing hormone 1.318
CD68 CD68 molecule 1.316
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 1.315
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.309
USP6 ubiquitin specific peptidase 6 1.303
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.298
ARMC5 armadillo repeat containing 5 1.298
SMAD3 SMAD family member 3 1.298
H3-3B H3.3 histone B 1.298
TSHR thyroid stimulating hormone receptor 1.298
OCRL oculocerebrorenal syndrome of Lowe 1.297
FURIN furin (paired basic amino acid cleaving enzyme) 1.295
FRZB frizzled-related protein 1.292
ESPN espin 1.29
PSPN persephin 1.29
PNMT phenylethanolamine N-methyltransferase 1.288
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.285
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.285
THRAP3 thyroid hormone receptor associated protein 3 1.277
ARRB1 arrestin, beta 1 1.276
HRAS Harvey rat sarcoma viral oncogene homolog 1.275
ADAM17 ADAM metallopeptidase domain 17 1.274
EPOR erythropoietin receptor 1.274
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.272
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.272
PLPPR4 phospholipid phosphatase related 4 1.271
WNT3A wingless-type MMTV integration site family, member 3A 1.271
MYH14 myosin, heavy chain 14, non-muscle 1.268
CD40LG CD40 ligand 1.267
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.266
XPR1 xenotropic and polytropic retrovirus receptor 1 1.264
ALK anaplastic lymphoma receptor tyrosine kinase 1.262
DPP4 dipeptidyl-peptidase 4 1.26
EPAS1 endothelial PAS domain protein 1 1.26
PECAM1 platelet/endothelial cell adhesion molecule 1 1.26
KLK3 kallikrein-related peptidase 3 1.258
IL18 interleukin 18 1.258
EGF epidermal growth factor 1.255
PTPRC protein tyrosine phosphatase, receptor type, C 1.253
DCSTAMP dendrocyte expressed seven transmembrane protein 1.25
VCAM1 vascular cell adhesion molecule 1 1.248
BCL2 B-cell CLL/lymphoma 2 1.248
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.245
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.243
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.241
CA2 carbonic anhydrase II 1.241
F3 coagulation factor III (thromboplastin, tissue factor) 1.239
RTP2 receptor (chemosensory) transporter protein 2 1.238
CHSY3 chondroitin sulfate synthase 3 1.237
GIP gastric inhibitory polypeptide 1.232
TAC1 tachykinin, precursor 1 1.231
CDKN2A cyclin-dependent kinase inhibitor 2A 1.231
RETN resistin 1.23
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.228
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.226
GPX7 glutathione peroxidase 7 1.226
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.225
GPX6 glutathione peroxidase 6 1.225
GPX5 glutathione peroxidase 5 1.224
AIRE autoimmune regulator 1.224
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 1.221
BAAT bile acid CoA:amino acid N-acyltransferase 1.219
SAMD9 sterile alpha motif domain containing 9 1.218
SLC26A6 solute carrier family 26 (anion exchanger), member 6 1.218
GPX8 glutathione peroxidase 8 (putative) 1.218
FBXO32 F-box protein 32 1.217
ZNF410 zinc finger protein 410 1.216
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.214
GPX3 glutathione peroxidase 3 1.213
GPX2 glutathione peroxidase 2 1.211
RETNLB resistin like beta 1.211
IFNA16 interferon, alpha 16 1.208
IFNA7 interferon, alpha 7 1.208
IFNA8 interferon, alpha 8 1.207
IFNA10 interferon, alpha 10 1.207
IFNA14 interferon, alpha 14 1.207
HIC1 hypermethylated in cancer 1 1.207
IFNA21 interferon, alpha 21 1.207
WNT16 wingless-type MMTV integration site family, member 16 1.206
IFNA5 interferon, alpha 5 1.206
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.202
IFNA4 interferon, alpha 4 1.202
IFNA2 interferon, alpha 2 1.201
CCK cholecystokinin 1.201
IFNA6 interferon, alpha 6 1.2
SOX9 SRY (sex determining region Y)-box 9 1.2
APOA1 apolipoprotein A-I 1.198
IFNA13 interferon, alpha 13 1.198
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.197
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.195
SFRP1 secreted frizzled-related protein 1 1.195
SSTR5 somatostatin receptor 5 1.193
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.191
TRPM7 transient receptor potential cation channel, subfamily M, member 7 1.19
PLPPR3 phospholipid phosphatase related 3 1.187
IFNA17 interferon, alpha 17 1.185
ARTN artemin 1.182
EGR1 early growth response 1 1.182
RHOA ras homolog family member A 1.18
MMP13 matrix metallopeptidase 13 1.175
WT1 Wilms tumor 1 1.17
ACE2 angiotensin I converting enzyme 2 1.169
SMAD2 SMAD family member 2 1.168
AVPR2 arginine vasopressin receptor 2 1.167
DICER1 dicer 1, ribonuclease type III 1.166
LEPR leptin receptor 1.166
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.162
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.162
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.16
NPY neuropeptide Y 1.16
PRDM2 PR domain containing 2, with ZNF domain 1.157
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.156
PTEN phosphatase and tensin homolog 1.155
KIF1B kinesin family member 1B 1.155
BMP6 bone morphogenetic protein 6 1.154
KRAS Kirsten rat sarcoma viral oncogene homolog 1.152
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.152
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.15
KDR kinase insert domain receptor 1.148
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 1.148
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.146
TBX1 T-box 1 1.146
CSDE1 cold shock domain containing E1, RNA-binding 1.146
HAVCR1 hepatitis A virus cellular receptor 1 1.145
AMBP alpha-1-microglobulin/bikunin precursor 1.143
CLDN2 claudin 2 1.141
CSF1R colony stimulating factor 1 receptor 1.141
SIRT1 sirtuin 1 1.14
GRM1 glutamate receptor, metabotropic 1 1.14
HNF4A hepatocyte nuclear factor 4, alpha 1.14
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.137
IFNA1 interferon, alpha 1 1.136
CCN2 cellular communication network factor 2 1.135
FGF21 fibroblast growth factor 21 1.134
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.134
NRTN neurturin 1.134
FGF19 fibroblast growth factor 19 1.133
BSPRY B-box and SPRY domain containing 1.132
PTRH2 peptidyl-tRNA hydrolase 2 1.131
LPA lipoprotein, Lp(a) 1.126
BRCA2 breast cancer 2, early onset 1.125
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.124
TAGLN transgelin 1.124
FOXN3 forkhead box N3 1.123
MME membrane metallo-endopeptidase 1.122
TCF4 transcription factor 4 1.122
FH fumarate hydratase 1.12
ICAM1 intercellular adhesion molecule 1 1.117
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.112
POSTN periostin, osteoblast specific factor 1.111
PAX5 paired box 5 1.111
ESR2 estrogen receptor 2 (ER beta) 1.111
CHKA choline kinase alpha 1.11
GRHPR glyoxylate reductase/hydroxypyruvate reductase 1.104
TH tyrosine hydroxylase 1.103
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.102
TPM3 tropomyosin 3 1.097
CP ceruloplasmin (ferroxidase) 1.094
IAPP islet amyloid polypeptide 1.093
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.093
LOX lysyl oxidase 1.091
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.089
VWF von Willebrand factor 1.088
TLR4 toll-like receptor 4 1.088
SGK1 serum/glucocorticoid regulated kinase 1 1.087
KLB klotho beta 1.087
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.085
CELA1 chymotrypsin-like elastase family, member 1 1.085
H3-3A H3.3 histone A 1.083
H3-4 H3.4 histone, cluster member 1.082
FGF1 fibroblast growth factor 1 (acidic) 1.082
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.082
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.08
NTS neurotensin 1.078
H3C13 H3 clustered histone 13 1.076
H3-5 H3.5 histone 1.076
UBXN11 UBX domain protein 11 1.073
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.073
TBCE tubulin folding cofactor E 1.072
CLCN2 chloride channel, voltage-sensitive 2 1.072
FGFR2 fibroblast growth factor receptor 2 1.072
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 1.071
AR androgen receptor 1.07
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.07
MPO myeloperoxidase 1.067
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 1.066
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.066
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.065
CALCA calcitonin-related polypeptide alpha 1.064
H3C12 H3 clustered histone 12 1.064
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 1.063
MXD3 MAX dimerization protein 3 1.061
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 1.06
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.059
TSC2 tuberous sclerosis 2 1.058
ACVR2A activin A receptor, type IIA 1.057
HP haptoglobin 1.057
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.056
ADGRG2 adhesion G protein-coupled receptor G2 1.055
PRTN3 proteinase 3 1.055
CSF3 colony stimulating factor 3 (granulocyte) 1.053
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.051
AHR aryl hydrocarbon receptor 1.05
OXA1L oxidase (cytochrome c) assembly 1-like 1.049
MB myoglobin 1.048
FST follistatin 1.048
FLNA filamin A, alpha 1.044
ADRB2 adrenoceptor beta 2, surface 1.041
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.04
CELA3B chymotrypsin-like elastase family, member 3B 1.034
CRTAP cartilage associated protein 1.033
PAX1 paired box 1 1.031
GFRA1 GDNF family receptor alpha 1 1.03
IRS1 insulin receptor substrate 1 1.029
WNT1 wingless-type MMTV integration site family, member 1 1.025
MMP2 matrix metallopeptidase 2 1.022
TOR1A torsin family 1, member A (torsin A) 1.022
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 1.02
DNTT DNA nucleotidylexotransferase 1.02
IL7 interleukin 7 1.018
CDX2 caudal type homeobox 2 1.018
OXT oxytocin/neurophysin I prepropeptide 1.017
TCEA3 transcription elongation factor A (SII), 3 1.017
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 1.017
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.014
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.014
SLC26A1 solute carrier family 26 (anion exchanger), member 1 1.014
KITLG KIT ligand 1.013
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.013
GJA1 gap junction protein, alpha 1, 43kDa 1.013
THBD thrombomodulin 1.013
SMAD9 SMAD family member 9 1.012
KLHL3 kelch-like family member 3 1.012
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.008
APOC2 apolipoprotein C-II 1.008
FOXO1 forkhead box O1 1.007
OSTM1 osteopetrosis associated transmembrane protein 1 1.005
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.004
APOC3 apolipoprotein C-III 1.003
CD40 CD40 molecule, TNF receptor superfamily member 5 1.002
TLR2 toll-like receptor 2 1.002
WNT5A wingless-type MMTV integration site family, member 5A 1.001
MYORG myogenesis regulating glycosidase (putative) 1.001