Hyperplasia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement.|An abnormal increase in the number of (otherwise normal) cells in an organ or a tissue with consequent enlargement. (Experimental Factor Ontology, EFO_0000536)
External Link https://www.disgenet.org/browser/0/1/0/C1290590
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Genes

223 genes associated with the disease Hyperplasia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABI1 abl-interactor 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADIPOQ adiponectin, C1Q and collagen domain containing
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMACR alpha-methylacyl-CoA racemase
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BAAT bile acid CoA:amino acid N-acyltransferase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BGN biglycan
BHLHE22 basic helix-loop-helix family, member e22
BIRC2 baculoviral IAP repeat containing 2
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD2 bromodomain containing 2
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALCR calcitonin receptor
CALR calreticulin
CCKBR cholecystokinin B receptor
CCL5 chemokine (C-C motif) ligand 5
CCR4 chemokine (C-C motif) receptor 4
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD86 CD86 molecule
CDH13 cadherin 13
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COX2
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CXCL8 chemokine (C-X-C motif) ligand 8
DCLK1 doublecortin-like kinase 1
DCTN6 dynactin 6
DEFA5 defensin, alpha 5, Paneth cell-specific
DLC1 DLC1 Rho GTPase activating protein
DSPP dentin sialophosphoprotein
DVL2 dishevelled segment polarity protein 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHB2 EPH receptor B2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F3 coagulation factor III (thromboplastin, tissue factor)
FAP fibroblast activation protein, alpha
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FOXP3 forkhead box P3
GAST gastrin
GCG glucagon
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GHR growth hormone receptor
GIF gastric intrinsic factor (vitamin B synthesis)
GLI1 GLI family zinc finger 1
GLP1R glucagon-like peptide 1 receptor
GPI glucose-6-phosphate isomerase
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
HAVCR1 hepatitis A virus cellular receptor 1
HDAC1 histone deacetylase 1
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HDAC9 histone deacetylase 9
HDGF hepatoma-derived growth factor
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNF1B HNF1 homeobox B
HP haptoglobin
IFI27 interferon, alpha-inducible protein 27
IFITM5 interferon induced transmembrane protein 5
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IHH indian hedgehog
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL4 interleukin 4
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
IRF1 interferon regulatory factor 1
KLF4 Kruppel-like factor 4 (gut)
KLK3 kallikrein-related peptidase 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LCN2 lipocalin 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MBD4 methyl-CpG binding domain protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MCM2 minichromosome maintenance complex component 2
MGMT O-6-methylguanine-DNA methyltransferase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MORC2 MORC family CW-type zinc finger 2
MPO myeloperoxidase
MPPED2 metallophosphoesterase domain containing 2
MRC1 mannose receptor, C type 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MT1A metallothionein 1A
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUTYH mutY homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEUROG1 neurogenin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NTHL1 nth endonuclease III-like 1 (E. coli)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OLIG2 oligodendrocyte lineage transcription factor 2
OR10A4 olfactory receptor, family 10, subfamily A, member 4
PANX3 pannexin 3
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM7 PDZ and LIM domain 7 (enigma)
PDX1 pancreatic and duodenal homeobox 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGPEP1 pyroglutamyl-peptidase I
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PRL prolactin
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RERE arginine-glutamic acid dipeptide (RE) repeats
RNF43 ring finger protein 43
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
SATB2 SATB homeobox 2
SCYL1 SCY1-like 1 (S. cerevisiae)
SDC2 syndecan 2
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP2 secreted frizzled-related protein 2
SHH sonic hedgehog
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD4 SMAD family member 4
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SPART spartin
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STRADA STE20-related kinase adaptor alpha
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TCL1A T-cell leukemia/lymphoma 1A
TCL1B T-cell leukemia/lymphoma 1B
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TICAM2 toll-like receptor adaptor molecule 2
TIMELESS timeless circadian clock
TIPE2 TNF alpha induced protein 8 like 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1
TRIM21 tripartite motif containing 21
TSPAN1 tetraspanin 1
VIM vimentin
WIF1 WNT inhibitory factor 1
WNT5A wingless-type MMTV integration site family, member 5A
ZGLP1 zinc finger, GATA-like protein 1