Hypersomnia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description a large group of disorders characterized by excessive daytime sleepiness (Experimental Factor Ontology, EFO_0005246)
External Link https://www.disgenet.org/browser/0/1/0/C0917799
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Genes

68 genes associated with the disease Hypersomnia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADRB3 adrenoceptor beta 3
AIP aryl hydrocarbon receptor interacting protein
AMOT angiomotin
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BRD4 bromodomain containing 4
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK9 cyclin-dependent kinase 9
CHKB choline kinase beta
CLOCK clock circadian regulator
COMT catechol-O-methyltransferase
CPT1B carnitine palmitoyltransferase 1B (muscle)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
EXOSC3 exosome component 3
FOXE1 forkhead box E1
GAL galanin/GMAP prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNLY granulysin
GPR101 G protein-coupled receptor 101
HACD1 3-hydroxyacyl-CoA dehydratase 1
HCRT hypocretin (orexin) neuropeptide precursor
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HRH3 histamine receptor H3
IL17A interleukin 17A
IL6 interleukin 6
IYD iodotyrosine deiodinase
LGALS3 lectin, galactoside-binding, soluble, 3
LIFR leukemia inhibitory factor receptor alpha
LNPEP leucyl/cystinyl aminopeptidase
MAPK8 mitogen-activated protein kinase 8
MCHR1 melanin-concentrating hormone receptor 1
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NCKAP5 NCK-associated protein 5
NKX2-1 NK2 homeobox 1
NKX2-5 NK2 homeobox 5
NPAS2 neuronal PAS domain protein 2
PAX8 paired box 8
PER2 period circadian clock 2
PHGDH phosphoglycerate dehydrogenase
PNPLA6 patatin-like phospholipase domain containing 6
PRL prolactin
PRNP prion protein
PSG5 pregnancy specific beta-1-glycoprotein 5
PTPA protein phosphatase 2 phosphatase activator
REM1 RAS (RAD and GEM)-like GTP-binding 1
S100A10 S100 calcium binding protein A10
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SHBG sex hormone-binding globulin
SIK3 SIK family kinase 3
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SORBS1 sorbin and SH3 domain containing 1
STAR steroidogenic acute regulatory protein
TDP2 tyrosyl-DNA phosphodiesterase 2
TG thyroglobulin
TPO thyroid peroxidase
TSHR thyroid stimulating hormone receptor
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)