Hypertrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells. (Experimental Factor Ontology, EFO_0002460)
External Link https://www.disgenet.org/browser/0/1/0/C0575518
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Genes

129 genes associated with the disease Hypertrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTN4 actinin, alpha 4
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALOX12 arachidonate 12-lipoxygenase
ANPEP alanyl (membrane) aminopeptidase
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATR ATR serine/threonine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTNL2 butyrophilin-like 2
CAT catalase
CCN2 cellular communication network factor 2
CD40LG CD40 ligand
CD96 CD96 molecule
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDK13 cyclin-dependent kinase 13
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDT1 chromatin licensing and DNA replication factor 1
CLDN7 claudin 7
CNR1 cannabinoid receptor 1 (brain)
COX7B cytochrome c oxidase subunit VIIb
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYSLTR1 cysteinyl leukotriene receptor 1
DCN decorin
DEFB1 defensin, beta 1
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DHCR7 7-dehydrocholesterol reductase
DMRT3 doublesex and mab-3 related transcription factor 3
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESR1 estrogen receptor 1
FAM58A family with sequence similarity 58, member A
FGFR2 fibroblast growth factor receptor 2
FIG4 FIG4 phosphoinositide 5-phosphatase
FRAS1 Fraser extracellular matrix complex subunit 1
FZD6 frizzled class receptor 6
G6PD glucose-6-phosphate dehydrogenase
GALNS galactosamine (N-acetyl)-6-sulfatase
GAST gastrin
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GCG glucagon
GMNN geminin, DNA replication inhibitor
GPX1 glutathione peroxidase 1
GSK3B glycogen synthase kinase 3 beta
HCCS holocytochrome c synthase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IDUA iduronidase, alpha-L-
IL10 interleukin 10
IL18 interleukin 18
IL21 interleukin 21
IL22 interleukin 22
IL37 interleukin 37
INSR insulin receptor
KAT6B K(lysine) acetyltransferase 6B
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KL klotho
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NPPB natriuretic peptide B
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
OCLN occludin
OR10A4 olfactory receptor, family 10, subfamily A, member 4
ORC1 origin recognition complex, subunit 1
ORC4 origin recognition complex, subunit 4
ORC6 origin recognition complex, subunit 6
PAEP progestagen-associated endometrial protein
PAGR1 PAXIP1 associated glutamate-rich protein 1
PEX1 peroxisomal biogenesis factor 1
PEX10 peroxisomal biogenesis factor 10
PEX11B peroxisomal biogenesis factor 11 beta
PEX12 peroxisomal biogenesis factor 12
PEX13 peroxisomal biogenesis factor 13
PEX14 peroxisomal biogenesis factor 14
PEX16 peroxisomal biogenesis factor 16
PEX19 peroxisomal biogenesis factor 19
PEX2 peroxisomal biogenesis factor 2
PEX26 peroxisomal biogenesis factor 26
PEX3 peroxisomal biogenesis factor 3
PEX5 peroxisomal biogenesis factor 5
PEX6 peroxisomal biogenesis factor 6
POR P450 (cytochrome) oxidoreductase
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PRKCA protein kinase C, alpha
RASA1 RAS p21 protein activator (GTPase activating protein) 1
REN renin
RPS19 ribosomal protein S19
RSPO1 R-spondin 1
SCGB3A1 secretoglobin, family 3A, member 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPD surfactant protein D
SIRT6 sirtuin 6
SLC12A9 solute carrier family 12, member 9
SOD2 superoxide dismutase 2, mitochondrial
SOX9 SRY (sex determining region Y)-box 9
SPATA7 spermatogenesis associated 7
SRY sex determining region Y
TALDO1 transaldolase 1
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TOE1 target of EGR1, member 1 (nuclear)
TRAIP TRAF interacting protein
UBE3B ubiquitin protein ligase E3B
UBR1 ubiquitin protein ligase E3 component n-recognin 1
VAC14 Vac14 homolog (S. cerevisiae)
VAMP7 vesicle-associated membrane protein 7
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
ZFPM2 zinc finger protein, FOG family member 2