Hyperuricemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood. (Human Disease Ontology, DOID_1920)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D033461
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Genes

48 genes/proteins associated with the disease Hyperuricemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.88009
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.88009
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.88009
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 2.88009
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 1.70035
TNF tumor necrosis factor 1.57971
CAT catalase 1.44193
VCAM1 vascular cell adhesion molecule 1 1.39198
TGFB1 transforming growth factor, beta 1 1.35705
NOS3 nitric oxide synthase 3 (endothelial cell) 1.33169
BCL2 B-cell CLL/lymphoma 2 1.27813
ICAM1 intercellular adhesion molecule 1 1.27316
CCL2 chemokine (C-C motif) ligand 2 1.26947
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.24087
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.2393
IL6 interleukin 6 1.22853
EDN1 endothelin 1 1.22469
PPARA peroxisome proliferator-activated receptor alpha 1.21011
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.20946
NOS2 nitric oxide synthase 2, inducible 1.20654
BAX BCL2-associated X protein 1.20622
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.17235
INS insulin 1.16866
BCL2L1 BCL2-like 1 1.15729
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.15357
IL1B interleukin 1, beta 1.14268
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.13929
CP ceruloplasmin (ferroxidase) 1.13041
REN renin 1.12185
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.10942
AGTR1 angiotensin II receptor, type 1 1.10631
FAS Fas cell surface death receptor 1.09401
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.09011
IL5 interleukin 5 1.0894
NPPA natriuretic peptide A 1.08196
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 1.08161
JUN jun proto-oncogene 1.07625
CCND1 cyclin D1 1.07199
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.05349
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.05126
IFNG interferon, gamma 1.04239
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.03789
IL12B interleukin 12B 1.03046
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.02971
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.02933
GUCA2A guanylate cyclase activator 2A (guanylin) 1.02336
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.01776
ACACA acetyl-CoA carboxylase alpha 1.01701