Hypoglycemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007003
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Genes

294 genes/proteins associated with the disease Hypoglycemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SOD2 superoxide dismutase 2, mitochondrial 2.88009
TNF tumor necrosis factor 2.88009
HNF1A HNF1 homeobox A 2.88009
INS insulin 2.88009
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.88009
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.88009
GSR glutathione reductase 2.88009
IGF2 insulin-like growth factor 2 2.88009
IL1B interleukin 1, beta 2.88009
PPARA peroxisome proliferator-activated receptor alpha 2.88009
IL6 interleukin 6 1.91101
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.87958
NOS2 nitric oxide synthase 2, inducible 1.85204
BAX BCL2-associated X protein 1.79063
LEP leptin 1.78568
IFNG interferon, gamma 1.76868
CAT catalase 1.73659
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.72842
FAS Fas cell surface death receptor 1.71461
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.71173
IL10 interleukin 10 1.68697
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.68232
TP53 tumor protein p53 1.67398
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.64235
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.63698
IL2 interleukin 2 1.62535
GSK3B glycogen synthase kinase 3 beta 1.62199
MAPK3 mitogen-activated protein kinase 3 1.62013
DDIT3 DNA-damage-inducible transcript 3 1.60337
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.59989
VEGFA vascular endothelial growth factor A 1.59264
REN renin 1.58865
CXCL8 chemokine (C-X-C motif) ligand 8 1.58631
VCAM1 vascular cell adhesion molecule 1 1.57594
ALB albumin 1.56312
MAPK1 mitogen-activated protein kinase 1 1.53844
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.52963
HMOX1 heme oxygenase 1 1.52566
CCL2 chemokine (C-C motif) ligand 2 1.5138
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 1.5118
NOS3 nitric oxide synthase 3 (endothelial cell) 1.4989
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.46041
BCL2 B-cell CLL/lymphoma 2 1.45063
IL1A interleukin 1, alpha 1.4479
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.44111
TLR4 toll-like receptor 4 1.43864
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.43157
GCG glucagon 1.42156
IL4 interleukin 4 1.40373
HSPB1 heat shock 27kDa protein 1 1.40204
IGF1R insulin-like growth factor 1 receptor 1.40036
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.39952
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.3903
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.38527
CCL3 chemokine (C-C motif) ligand 3 1.38298
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.38156
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.37733
TGFB1 transforming growth factor, beta 1 1.37103
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.36447
FN1 fibronectin 1 1.36447
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.35357
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.34635
ADRB1 adrenoceptor beta 1 1.34576
NRAP nebulin-related anchoring protein 1.34459
CYBB cytochrome b-245, beta polypeptide 1.34372
GPX1 glutathione peroxidase 1 1.34372
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.34082
POMC proopiomelanocortin 1.34024
JUNB jun B proto-oncogene 1.33612
G6PD glucose-6-phosphate dehydrogenase 1.33052
CCND1 cyclin D1 1.32993
IRS1 insulin receptor substrate 1 1.32993
ICAM1 intercellular adhesion molecule 1 1.32964
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.32667
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.32577
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.32577
GJA1 gap junction protein, alpha 1, 43kDa 1.32458
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.32132
COL3A1 collagen, type III, alpha 1 1.32044
NFE2L2 nuclear factor, erythroid 2-like 2 1.31506
PRPF19 pre-mRNA processing factor 19 1.30696
EGFR epidermal growth factor receptor 1.30635
NUPR1 nuclear protein, transcriptional regulator, 1 1.30574
MMP13 matrix metallopeptidase 13 1.3039
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.29936
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.29781
PLIN2 perilipin 2 1.29011
SCARB1 scavenger receptor class B, member 1 1.28425
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.27595
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.27564
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.27409
PBX2 pre-B-cell leukemia homeobox 2 1.27378
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.27101
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.26638
PNPLA2 patatin-like phospholipase domain containing 2 1.26267
USP9X ubiquitin specific peptidase 9, X-linked 1.26175
APP amyloid beta (A4) precursor protein 1.2599
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.25807
COL5A3 collagen, type V, alpha 3 1.25619
LY6D lymphocyte antigen 6 complex, locus D 1.25619
AVP arginine vasopressin 1.25307
ARPP19 cAMP-regulated phosphoprotein, 19kDa 1.25028
SOD1 superoxide dismutase 1, soluble 1.24812
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.24244
JUN jun proto-oncogene 1.24087
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.23648
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.23488
PRKCA protein kinase C, alpha 1.23488
CALR calreticulin 1.2336
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.23169
PRKCE protein kinase C, epsilon 1.22758
PRKCB protein kinase C, beta 1.22566
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.22469
PARP1 poly (ADP-ribose) polymerase 1 1.22436
UBC ubiquitin C 1.22112
CTGF connective tissue growth factor 1.22016
BBC3 BCL2 binding component 3 1.21951
CD151 CD151 molecule (Raph blood group) 1.21887
DGAT2 diacylglycerol O-acyltransferase 2 1.21791
CYBA cytochrome b-245, alpha polypeptide 1.21727
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.21534
APOA1 apolipoprotein A-I 1.21304
FABP1 fatty acid binding protein 1, liver 1.20946
APOE apolipoprotein E 1.20848
MAP2K2 mitogen-activated protein kinase kinase 2 1.20751
GH1 growth hormone 1 1.20558
PKNOX2 PBX/knotted 1 homeobox 2 1.20163
PLCG1 phospholipase C, gamma 1 1.20064
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.19607
SDS serine dehydratase 1.19509
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.19477
RIOK2 RIO kinase 2 1.19279
NPY neuropeptide Y 1.19047
EDNRB endothelin receptor type B 1.19047
NET1 neuroepithelial cell transforming 1 1.19047
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.18783
ODC1 ornithine decarboxylase 1 1.18521
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.18456
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.18424
PPARG peroxisome proliferator-activated receptor gamma 1.18424
STAR steroidogenic acute regulatory protein 1.18391
MAPK8 mitogen-activated protein kinase 8 1.18259
DMXL2 Dmx-like 2 1.17596
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.17366
LAMB1 laminin, beta 1 1.17333
COL1A1 collagen, type I, alpha 1 1.17067
FOS FBJ murine osteosarcoma viral oncogene homolog 1.16933
LCN2 lipocalin 2 1.16733
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.166
ACTB actin, beta 1.16203
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.16035
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.16035
GSTM1 glutathione S-transferase mu 1 1.15627
CKB creatine kinase, brain 1.15593
MAPK9 mitogen-activated protein kinase 9 1.15593
FOXO1 forkhead box O1 1.15122
SEPP1 selenoprotein P, plasma, 1 1.15122
CTSD cathepsin D 1.14885
FOSL1 FOS-like antigen 1 1.14713
BCL2L1 BCL2-like 1 1.14644
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.14541
NOX4 NADPH oxidase 4 1.14404
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.14302
CXCL12 chemokine (C-X-C motif) ligand 12 1.142
ORM2 orosomucoid 2 1.142
TOB1 transducer of ERBB2, 1 1.14166
EGR1 early growth response 1 1.13929
PRKCD protein kinase C, delta 1.13895
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 1.13793
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.13484
IL13 interleukin 13 1.13415
INSR insulin receptor 1.13245
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 1.13211
SEPT2 septin 2 1.13177
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.12599
FKBP5 FK506 binding protein 5 1.12357
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 1.12357
CTSL cathepsin L 1.12117
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.12014
ADRB2 adrenoceptor beta 2, surface 1.12014
CREB1 cAMP responsive element binding protein 1 1.11707
SIRT1 sirtuin 1 1.11707
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.11673
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.11571
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.11466
CUL1 cullin 1 1.1129
ADORA1 adenosine A1 receptor 1.11255
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.11255
G6PC glucose-6-phosphatase, catalytic subunit 1.10838
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.10665
PF4 platelet factor 4 1.10317
RPS6 ribosomal protein S6 1.10211
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.09998
PYGL phosphorylase, glycogen, liver 1.09681
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.09681
FGF21 fibroblast growth factor 21 1.09681
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 1.09506
LPIN1 lipin 1 1.09332
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.0919
RGS2 regulator of G-protein signaling 2 1.0919
KIF3A kinesin family member 3A 1.08975
COL15A1 collagen, type XV, alpha 1 1.0894
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.0894
TIMP3 TIMP metallopeptidase inhibitor 3 1.08797
MAOB monoamine oxidase B 1.08797
CAPN1 calpain 1, (mu/I) large subunit 1.08478
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.08372
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.08231
THBS1 thrombospondin 1 1.08196
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.07875
CD81 CD81 molecule 1.0784
XDH xanthine dehydrogenase 1.07696
NPPA natriuretic peptide A 1.07696
FASLG Fas ligand (TNF superfamily, member 6) 1.07447
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 1.07305
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.07305
CPNE8 copine VIII 1.07305
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.07234
KEAP1 kelch-like ECH-associated protein 1 1.07057
MCL1 myeloid cell leukemia 1 1.07022
SREBF1 sterol regulatory element binding transcription factor 1 1.06917
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.06881
CD93 CD93 molecule 1.06771
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.06625
CYR61 cysteine-rich, angiogenic inducer, 61 1.06479
GJA4 gap junction protein, alpha 4, 37kDa 1.06261
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.06261
ADIPOQ adiponectin, C1Q and collagen domain containing 1.06116
PECAM1 platelet/endothelial cell adhesion molecule 1 1.05793
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.05498
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.05386
GMFB glia maturation factor, beta 1.05312
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.05237
ADRB3 adrenoceptor beta 3 1.05237
TH tyrosine hydroxylase 1.04941
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.04831
LPL lipoprotein lipase 1.04794
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.04794
FOSL2 FOS-like antigen 2 1.04647
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.04647
NCF1 neutrophil cytosolic factor 1 1.04276
COL4A1 collagen, type IV, alpha 1 1.04126
IL17A interleukin 17A 1.04126
GATA3 GATA binding protein 3 1.04126
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 1.04014
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.03939
CYCS cytochrome c, somatic 1.03864
TGFBR1 transforming growth factor, beta receptor 1 1.03864
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1.03827
UBE2B ubiquitin-conjugating enzyme E2B 1.03827
PRKD3 protein kinase D3 1.03827
F3 coagulation factor III (thromboplastin, tissue factor) 1.03752
AGTR1 angiotensin II receptor, type 1 1.03604
PER2 period circadian clock 2 1.03604
GRN granulin 1.03567
HCK HCK proto-oncogene, Src family tyrosine kinase 1.03382
PPAT phosphoribosyl pyrophosphate amidotransferase 1.03345
COG3 component of oligomeric golgi complex 3 1.03159
MAP2K6 mitogen-activated protein kinase kinase 6 1.03084
IGFBP1 insulin-like growth factor binding protein 1 1.03084
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.03084
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.03046
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.02933
GCLC glutamate-cysteine ligase, catalytic subunit 1.02896
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.02896
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.02821
GSTP1 glutathione S-transferase pi 1 1.02634
PRL prolactin 1.02559
COL7A1 collagen, type VII, alpha 1 1.02522
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.02522
COL8A1 collagen, type VIII, alpha 1 1.02447
ACO2 aconitase 2, mitochondrial 1.02299
CAV1 caveolin 1, caveolae protein, 22kDa 1.02225
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.02188
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.02151
PRDM16 PR domain containing 16 1.02077
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.02077
CD44 CD44 molecule (Indian blood group) 1.0189
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.01663
PER3 period circadian clock 3 1.01663
ACAA1 acetyl-CoA acyltransferase 1 1.01625
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.01587
ACE angiotensin I converting enzyme 1.01587
FABP4 fatty acid binding protein 4, adipocyte 1.01549
TIMP2 TIMP metallopeptidase inhibitor 2 1.01549
CDK2 cyclin-dependent kinase 2 1.01474
MMP3 matrix metallopeptidase 3 1.01399
GCK glucokinase (hexokinase 4) 1.01324
FBXL3 F-box and leucine-rich repeat protein 3 1.01249
PHF10 PHD finger protein 10 1.01249
PLA1A phospholipase A1 member A 1.01174
USP48 ubiquitin specific peptidase 48 1.01174
IL12B interleukin 12B 1.01137
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.01025