Hypogonadism Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A gonadal disease that is characterized by diminished functional activity of the gonads. (Human Disease Ontology, DOID_1924)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007006
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Genes

48 genes/proteins associated with the disease Hypogonadism from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.88009
LHB luteinizing hormone beta polypeptide 2.88009
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.88009
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.88009
LEP leptin 2.88009
TAC3 tachykinin 3 2.88009
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.88009
GNRHR gonadotropin-releasing hormone receptor 2.88009
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.88009
TACR3 tachykinin receptor 3 2.88009
PRL prolactin 2.88009
LEPR leptin receptor 2.88009
FSHB follicle stimulating hormone, beta polypeptide 2.88009
CGB chorionic gonadotropin, beta polypeptide 2.88009
HEPH hephaestin 1.20719
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.18915
TGFB1 transforming growth factor, beta 1 1.16035
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.1556
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.12872
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 1.12634
HOMER1 homer scaffolding protein 1 1.12599
TMCC3 transmembrane and coiled-coil domain family 3 1.12599
NOS2 nitric oxide synthase 2, inducible 1.12323
ARRDC3 arrestin domain containing 3 1.12288
CSHL1 chorionic somatomammotropin hormone-like 1 1.12082
EDNRB endothelin receptor type B 1.12048
POMC proopiomelanocortin 1.10493
GSK3B glycogen synthase kinase 3 beta 1.09436
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.0919
FBLIM1 filamin binding LIM protein 1 1.08337
PRKCD protein kinase C, delta 1.07804
CCK cholecystokinin 1.07482
COMT catechol-O-methyltransferase 1.05936
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.05685
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.05648
CYTIP cytohesin 1 interacting protein 1.04831
AOC3 amine oxidase, copper containing 3 1.04757
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.04314
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.03901
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.03567
MAPK3 mitogen-activated protein kinase 3 1.0353
G6PD glucose-6-phosphate dehydrogenase 1.03419
EGR1 early growth response 1 1.03271
VIM vimentin 1.02708
SLC38A4 solute carrier family 38, member 4 1.01739
IGF1 insulin-like growth factor 1 (somatomedin C) 1.01399
STAR steroidogenic acute regulatory protein 1.01212
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.01062