Hypohidrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

218 genes co-occuring with the disease Hypohidrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
GLA galactosidase, alpha 3.519
EDARADD EDAR-associated death domain 3.193
EDAR ectodysplasin A receptor 3.136
EDA ectodysplasin A 3.112
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.963
NGF nerve growth factor (beta polypeptide) 2.701
WNT10A wingless-type MMTV integration site family, member 10A 2.486
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 2.34
CLDN10 claudin 10 2.324
NIPAL4 NIPA-like domain containing 4 2.318
COG6 component of oligomeric golgi complex 6 2.307
PNPLA1 patatin-like phospholipase domain containing 1 2.307
ALPK1 alpha-kinase 1 2.306
TGM1 transglutaminase 1 2.283
STIM1 stromal interaction molecule 1 2.259
PRDM12 PR domain containing 12 2.248
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.225
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.223
ALOXE3 arachidonate lipoxygenase 3 2.218
ALOX12B arachidonate 12-lipoxygenase, 12R type 2.206
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.134
AQP5 aquaporin 5 2.121
SCN9A sodium channel, voltage gated, type IX alpha subunit 2.109
ELP1 elongator acetyltransferase complex subunit 1 2.059
NGFR nerve growth factor receptor 2.048
CERS3 ceramide synthase 3 2.03
FAM111B family with sequence similarity 111, member B 2.013
STIM2 stromal interaction molecule 2 1.995
EDA2R ectodysplasin A2 receptor 1.99
BEST2 bestrophin 2 1.987
TSPEAR thrombospondin-type laminin G domain and EAR repeats 1.961
PAX9 paired box 9 1.949
DCD dermcidin 1.939
ORAI1 ORAI calcium release-activated calcium modulator 1 1.928
CLDN16 claudin 16 1.925
OR6C74 olfactory receptor, family 6, subfamily C, member 74 1.911
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 1.891
CLDN19 claudin 19 1.876
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 1.845
ACTRT1 actin-related protein T1 1.842
NAGA N-acetylgalactosaminidase, alpha- 1.832
CHRM3 cholinergic receptor, muscarinic 3 1.815
TP63 tumor protein p63 1.8
GJB6 gap junction protein, beta 6, 30kDa 1.766
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.757
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.749
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.734
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.73
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.727
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.718
OR4A15 olfactory receptor, family 4, subfamily A, member 15 1.715
MSX1 msh homeobox 1 1.707
WNK1 WNK lysine deficient protein kinase 1 1.687
ST14 suppression of tumorigenicity 14 (colon carcinoma) 1.674
GJB2 gap junction protein, beta 2, 26kDa 1.648
KIF1A kinesin family member 1A 1.643
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.635
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.633
KRT85 keratin 85, type II 1.627
RETREG1 reticulophagy regulator 1 1.623
KRT1 keratin 1, type II 1.614
KRT14 keratin 14, type I 1.612
KDF1 keratinocyte differentiation factor 1 1.608
SPINK5 serine peptidase inhibitor, Kazal type 5 1.601
ALB albumin 1.575
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.566
FERMT1 fermitin family member 1 1.558
COG1 component of oligomeric golgi complex 1 1.543
COG5 component of oligomeric golgi complex 5 1.542
KRT83 keratin 83, type II 1.533
LIPN lipase, family member N 1.529
ANO1 anoctamin 1, calcium activated chloride channel 1.526
TAC1 tachykinin, precursor 1 1.525
ZFHX2 zinc finger homeobox 2 1.524
SCN10A sodium channel, voltage gated, type X alpha subunit 1.498
BDNF brain-derived neurotrophic factor 1.497
ORAI2 ORAI calcium release-activated calcium modulator 2 1.495
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.491
ACE angiotensin I converting enzyme 1.49
FLG filaggrin 1.489
COG8 component of oligomeric golgi complex 8 1.486
TNF tumor necrosis factor 1.482
KRT10 keratin 10, type I 1.473
KRT2 keratin 2, type II 1.473
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.468
VIP vasoactive intestinal peptide 1.467
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1.467
RPL36A-HNRNPH2 RPL36A-HNRNPH2 readthrough 1.46
ORAI3 ORAI calcium release-activated calcium modulator 3 1.458
PRSS8 protease, serine, 8 1.455
CLDN14 claudin 14 1.455
GJB4 gap junction protein, beta 4, 30.3kDa 1.445
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.443
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.443
FLG2 filaggrin family member 2 1.442
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.441
COG7 component of oligomeric golgi complex 7 1.441
CRLF1 cytokine receptor-like factor 1 1.433
CLDN3 claudin 3 1.429
OR51A7 olfactory receptor, family 51, subfamily A, member 7 1.426
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 1.424
MPDU1 mannose-P-dolichol utilization defect 1 1.419
SMAD9 SMAD family member 9 1.411
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.41
KRT74 keratin 74, type II 1.403
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.4
SRD5A3 steroid 5 alpha-reductase 3 1.377
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.374
RFC1 replication factor C (activator 1) 1, 145kDa 1.362
KCTD1 potassium channel tetramerization domain containing 1 1.358
CASP14 caspase 14, apoptosis-related cysteine peptidase 1.355
NTF4 neurotrophin 4 1.347
TTR transthyretin 1.344
CLDN1 claudin 1 1.331
PORCN porcupine homolog (Drosophila) 1.318
DNAH8 dynein, axonemal, heavy chain 8 1.304
KREMEN1 kringle containing transmembrane protein 1 1.296
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 1.295
HOXC13 homeobox C13 1.288
UGCG UDP-glucose ceramide glucosyltransferase 1.287
POMC proopiomelanocortin 1.286
FURIN furin (paired basic amino acid cleaving enzyme) 1.286
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 1.285
COG4 component of oligomeric golgi complex 4 1.283
PKP1 plakophilin 1 1.283
NTF3 neurotrophin 3 1.278
COG3 component of oligomeric golgi complex 3 1.273
CDSN corneodesmosin 1.272
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.27
IVL involucrin 1.268
MPLKIP M-phase specific PLK1 interacting protein 1.265
CHUK conserved helix-loop-helix ubiquitous kinase 1.262
TIFA TRAF-interacting protein with forkhead-associated domain 1.257
CRP C-reactive protein, pentraxin-related 1.254
CLCA4 chloride channel accessory 4 1.245
RIPK4 receptor-interacting serine-threonine kinase 4 1.245
AXIN2 axin 2 1.244
CLCA2 chloride channel accessory 2 1.244
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.241
REN renin 1.22
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.218
SCN1A sodium channel, voltage gated, type I alpha subunit 1.207
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.205
CLCNKB chloride channel, voltage-sensitive Kb 1.204
KRT9 keratin 9, type I 1.203
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.198
EVC2 Ellis van Creveld syndrome 2 1.197
SPRR2A small proline-rich protein 2A 1.196
GJB3 gap junction protein, beta 3, 31kDa 1.187
INS insulin 1.187
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.184
BSND barttin CLCNK-type chloride channel accessory beta subunit 1.182
SAMD9 sterile alpha motif domain containing 9 1.181
CD8A CD8a molecule 1.178
DOLK dolichol kinase 1.172
CD4 CD4 molecule 1.172
IL1B interleukin 1, beta 1.171
CLDN7 claudin 7 1.168
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.168
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.163
RECQL4 RecQ protein-like 4 1.159
DPYSL5 dihydropyrimidinase-like 5 1.155
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.151
SNAP29 synaptosomal-associated protein, 29kDa 1.136
FOXA1 forkhead box A1 1.133
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.128
CA2 carbonic anhydrase II 1.122
SPRR2B small proline-rich protein 2B 1.119
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.115
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.114
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.111
CLCA1 chloride channel accessory 1 1.11
AMPH amphiphysin 1.106
IDS iduronate 2-sulfatase 1.103
LTBP3 latent transforming growth factor beta binding protein 3 1.102
ENAM enamelin 1.097
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.091
CKMT1B creatine kinase, mitochondrial 1B 1.09
AMBN ameloblastin (enamel matrix protein) 1.088
CKB creatine kinase, brain 1.087
CKM creatine kinase, muscle 1.086
WDR35 WD repeat domain 35 1.083
IL6 interleukin 6 1.082
LTBP2 latent transforming growth factor beta binding protein 2 1.072
DSG1 desmoglein 1 1.071
NPPB natriuretic peptide B 1.066
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.063
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 1.063
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.063
LRP6 low density lipoprotein receptor-related protein 6 1.063
CST3 cystatin C 1.061
PTH parathyroid hormone 1.06
IFT122 intraflagellar transport 122 1.059
NDN necdin, melanoma antigen (MAGE) family member 1.059
SARAF store-operated calcium entry-associated regulatory factor 1.055
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.054
CLDN2 claudin 2 1.052
DSP desmoplakin 1.052
IGLON5 IgLON family member 5 1.049
LGI1 leucine-rich, glioma inactivated 1 1.045
SHD Src homology 2 domain containing transforming protein D 1.044
CRACR2A calcium release activated channel regulator 2A 1.044
OR7A17 olfactory receptor, family 7, subfamily A, member 17 1.035
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.028
KCNK18 potassium channel, two pore domain subfamily K, member 18 1.027
TH tyrosine hydroxylase 1.027
ACHE acetylcholinesterase (Yt blood group) 1.023
TRPV3 transient receptor potential cation channel, subfamily V, member 3 1.023
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.018
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 1.018
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.016
KRT24 keratin 24, type I 1.013
CLDN11 claudin 11 1.01
SHH sonic hedgehog 1.009
DST dystonin 1.007
FOS FBJ murine osteosarcoma viral oncogene homolog 1.007
TFG TRK-fused gene 1.002
COG2 component of oligomeric golgi complex 2 1.002