Hypokinesia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Abnormally diminished motor activity. In contrast to paralysis, hypokinesia is not characterized by a lack of motor strength, but rather by a poverty of movement. The typical habitual movements (e.g., folding the arms, crossing the legs) are reduced in frequency. (Human Phenotype Ontology, HP_0002375)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018476
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Genes

620 genes/proteins associated with the disease Hypokinesia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
APOD apolipoprotein D 2.88009
OPRL1 opiate receptor-like 1 2.88009
GCH1 GTP cyclohydrolase 1 2.88009
FOS FBJ murine osteosarcoma viral oncogene homolog 2.49932
DRD2 dopamine receptor D2 2.46967
BDNF brain-derived neurotrophic factor 2.46331
TH tyrosine hydroxylase 2.4441
CAT catalase 2.42553
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.35368
PRL prolactin 2.34144
MAPK1 mitogen-activated protein kinase 1 2.33399
MAPK3 mitogen-activated protein kinase 3 2.32178
BCL2 B-cell CLL/lymphoma 2 2.31114
BAX BCL2-associated X protein 2.30339
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.29823
TNF tumor necrosis factor 2.24165
ACHE acetylcholinesterase (Yt blood group) 2.22142
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.1317
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.12091
CRH corticotropin releasing hormone 2.11922
TP53 tumor protein p53 2.11821
CREB1 cAMP responsive element binding protein 1 2.11764
SOD1 superoxide dismutase 1, soluble 2.11045
DRD1 dopamine receptor D1 2.10408
PENK proenkephalin 2.08728
EGR1 early growth response 1 2.07745
JUN jun proto-oncogene 2.05758
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.05495
SOD2 superoxide dismutase 2, mitochondrial 2.04755
DRD3 dopamine receptor D3 2.03252
POMC proopiomelanocortin 2.01773
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.0101
GSK3B glycogen synthase kinase 3 beta 2.00495
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 2.00384
GFAP glial fibrillary acidic protein 2.00056
NPY neuropeptide Y 1.99786
NOS2 nitric oxide synthase 2, inducible 1.98726
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.97405
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.97376
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.96476
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.95827
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.95767
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.9539
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.95345
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.9495
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.94814
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.9296
MAOA monoamine oxidase A 1.92928
MAOB monoamine oxidase B 1.90375
ARC activity-regulated cytoskeleton-associated protein 1.88885
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.87892
IL1B interleukin 1, beta 1.85433
TAC1 tachykinin, precursor 1 1.84817
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.84464
LHB luteinizing hormone beta polypeptide 1.84126
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.83717
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.83095
IFNG interferon, gamma 1.82202
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.80265
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.79446
STAR steroidogenic acute regulatory protein 1.79178
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.78052
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.77257
FSHB follicle stimulating hormone, beta polypeptide 1.76771
CDK5 cyclin-dependent kinase 5 1.76733
HMOX1 heme oxygenase 1 1.76289
JUNB jun B proto-oncogene 1.7564
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.74842
GSTP1 glutathione S-transferase pi 1 1.74741
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.74541
MAPK8 mitogen-activated protein kinase 8 1.73659
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.72654
ESR1 estrogen receptor 1 1.72281
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.7185
INS insulin 1.71565
COMT catechol-O-methyltransferase 1.70823
LDLR low density lipoprotein receptor 1.70471
AVP arginine vasopressin 1.70056
VEGFA vascular endothelial growth factor A 1.6993
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.69617
RELN reelin 1.69189
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.68506
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.6774
FAS Fas cell surface death receptor 1.67569
GSR glutathione reductase 1.67289
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.66102
ADORA2A adenosine A2a receptor 1.65643
NFE2L2 nuclear factor, erythroid 2-like 2 1.65555
GH1 growth hormone 1 1.64618
GPX1 glutathione peroxidase 1 1.63855
SCN10A sodium channel, voltage gated, type X alpha subunit 1.63698
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.63027
OPRM1 opioid receptor, mu 1 1.62646
HINT1 histidine triad nucleotide binding protein 1 1.62423
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.61365
CHGA chromogranin A 1.61201
GDNF glial cell derived neurotrophic factor 1.60897
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.60012
CES2 carboxylesterase 2 1.59755
IL6 interleukin 6 1.59614
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.59614
IL2 interleukin 2 1.59427
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.59381
RGS2 regulator of G-protein signaling 2 1.58303
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.58303
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.57594
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.57354
SREBF1 sterol regulatory element binding transcription factor 1 1.57114
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.56582
CCND1 cyclin D1 1.56214
ODC1 ornithine decarboxylase 1 1.55971
TGFB1 transforming growth factor, beta 1 1.54184
RGS9 regulator of G-protein signaling 9 1.53772
PVALB parvalbumin 1.53675
NUPR1 nuclear protein, transcriptional regulator, 1 1.52187
HSPA8 heat shock 70kDa protein 8 1.51506
EGR2 early growth response 2 1.5108
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.5065
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.50018
SCN1B sodium channel, voltage gated, type I beta subunit 1.49864
DDIT3 DNA-damage-inducible transcript 3 1.49096
PDYN prodynorphin 1.48967
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.48813
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.48582
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.48351
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.48351
VIP vasoactive intestinal peptide 1.48325
BCL2L1 BCL2-like 1 1.48273
PARP1 poly (ADP-ribose) polymerase 1 1.4794
NCAM1 neural cell adhesion molecule 1 1.4794
HPCA hippocalcin 1.47711
PRKCD protein kinase C, delta 1.47582
CCL2 chemokine (C-C motif) ligand 2 1.47322
SREBF2 sterol regulatory element binding transcription factor 2 1.47141
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.46462
REN renin 1.46251
APP amyloid beta (A4) precursor protein 1.46067
FASN fatty acid synthase 1.45989
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.45511
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.4522
TXNIP thioredoxin interacting protein 1.45089
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.4479
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.44436
SST somatostatin 1.4294
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.42913
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.42374
ELK1 ELK1, member of ETS oncogene family 1.42238
GNAS GNAS complex locus 1.42047
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.42047
IGF1 insulin-like growth factor 1 (somatomedin C) 1.41992
GAL galanin/GMAP prepropeptide 1.41884
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.41559
NTS neurotensin 1.41559
MAP2 microtubule-associated protein 2 1.41559
GRIK2 glutamate receptor, ionotropic, kainate 2 1.41478
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.41257
CTSB cathepsin B 1.41202
MAPK14 mitogen-activated protein kinase 14 1.41091
GRM1 glutamate receptor, metabotropic 1 1.40815
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.40623
CCK cholecystokinin 1.40541
GJA1 gap junction protein, alpha 1, 43kDa 1.40401
DRD4 dopamine receptor D4 1.40345
TFRC transferrin receptor 1.39422
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.39282
EGFR epidermal growth factor receptor 1.39058
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.38974
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.3878
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.38555
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.38555
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.3827
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.38213
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.38128
GRM5 glutamate receptor, metabotropic 5 1.38128
BBC3 BCL2 binding component 3 1.37018
GSTA4 glutathione S-transferase alpha 4 1.36648
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.36591
GSTA1 glutathione S-transferase alpha 1 1.3639
NOS1 nitric oxide synthase 1 (neuronal) 1.36275
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.36076
DUSP6 dual specificity phosphatase 6 1.36076
SENP6 SUMO1/sentrin specific peptidase 6 1.35184
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.35127
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.34547
ADCY5 adenylate cyclase 5 1.34547
COX7C cytochrome c oxidase subunit VIIc 1.34547
EDN1 endothelin 1 1.34489
MAPK9 mitogen-activated protein kinase 9 1.3443
SYT4 synaptotagmin IV 1.34285
VGF VGF nerve growth factor inducible 1.33995
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.33909
ALB albumin 1.3382
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.33434
CARTPT CART prepropeptide 1.33434
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.33434
QKI QKI, KH domain containing, RNA binding 1.33405
SRP9 signal recognition particle 9kDa 1.33405
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.33287
PINK1 PTEN induced putative kinase 1 1.32905
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.32607
PHF14 PHD finger protein 14 1.32577
EFNB3 ephrin-B3 1.32577
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.32518
PPARG peroxisome proliferator-activated receptor gamma 1.32488
CHRM1 cholinergic receptor, muscarinic 1 1.32339
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.32339
CXCL8 chemokine (C-X-C motif) ligand 8 1.32221
GSK3A glycogen synthase kinase 3 alpha 1.31837
EN2 engrailed homeobox 2 1.31566
OXT oxytocin/neurophysin I prepropeptide 1.31506
TFF1 trefoil factor 1 1.31446
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.31416
G6PD glucose-6-phosphate dehydrogenase 1.31267
TAGLN transgelin 1.31237
IL10 interleukin 10 1.31148
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.30819
CTSL cathepsin L 1.30696
TRIM2 tripartite motif containing 2 1.30299
FGF2 fibroblast growth factor 2 (basic) 1.30087
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.29966
BCHE butyrylcholinesterase 1.2975
HRAS Harvey rat sarcoma viral oncogene homolog 1.29595
GSTM1 glutathione S-transferase mu 1 1.29533
MCL1 myeloid cell leukemia 1 1.2944
CYCS cytochrome c, somatic 1.2941
KLF6 Kruppel-like factor 6 1.29379
PDIA6 protein disulfide isomerase family A, member 6 1.2861
ADRA2A adrenoceptor alpha 2A 1.28272
GCLC glutamate-cysteine ligase, catalytic subunit 1.28241
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.27966
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.27905
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.27875
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.2744
CP ceruloplasmin (ferroxidase) 1.27378
ADCY9 adenylate cyclase 9 1.26576
GPATCH4 G patch domain containing 4 1.26576
ADCK3 aarF domain containing kinase 3 1.26514
S100B S100 calcium binding protein B 1.26329
SPP1 secreted phosphoprotein 1 1.26329
EPO erythropoietin 1.26175
FKBP1A FK506 binding protein 1A, 12kDa 1.26083
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.26021
GRK6 G protein-coupled receptor kinase 6 1.25929
GAP43 growth associated protein 43 1.25713
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.25651
SHH sonic hedgehog 1.25651
BIRC5 baculoviral IAP repeat containing 5 1.25463
RET ret proto-oncogene 1.254
ANXA5 annexin A5 1.25245
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.24997
TPI1 triosephosphate isomerase 1 1.24812
FABP1 fatty acid binding protein 1, liver 1.24781
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.24623
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.24591
MAP2K2 mitogen-activated protein kinase kinase 2 1.2456
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.24401
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.24401
TXN thioredoxin 1.24338
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.24087
IRS1 insulin receptor substrate 1 1.23868
CALCA calcitonin-related polypeptide alpha 1.2368
CCND3 cyclin D3 1.23424
GOLGA4 golgin A4 1.23392
S100A4 S100 calcium binding protein A4 1.23328
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.23233
KIF1B kinesin family member 1B 1.23169
NUCLEOLIN nucleolin multifunctional protein 1.23169
HOMER1 homer scaffolding protein 1 1.23169
PARK7 parkinson protein 7 1.22758
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.22758
MAP2K1 mitogen-activated protein kinase kinase 1 1.22632
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.22371
CALB2 calbindin 2 1.22209
PRKCI protein kinase C, iota 1.22177
FN1 fibronectin 1 1.22112
SC5D sterol-C5-desaturase 1.21984
HRH1 histamine receptor H1 1.21599
STX4 syntaxin 4 1.21599
IKBIP IKBKB interacting protein 1.21271
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.21271
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.21043
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.21043
CES1 carboxylesterase 1 1.20622
TTR transthyretin 1.20622
APOE apolipoprotein E 1.2059
CYC1 cytochrome c-1 1.20493
XBP1 X-box binding protein 1 1.20394
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.19933
VIM vimentin 1.199
NPPA natriuretic peptide A 1.199
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 1.1977
NES nestin 1.19704
MAPT microtubule-associated protein tau 1.19574
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.19542
PGR progesterone receptor 1.19477
PRRC2A proline-rich coiled-coil 2A 1.19477
RAB21 RAB21, member RAS oncogene family 1.19445
API5 apoptosis inhibitor 5 1.19445
NT5C2 5'-nucleotidase, cytosolic II 1.19445
WBP4 WW domain binding protein 4 1.19445
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 1.19445
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.19412
FANCG Fanconi anemia, complementation group G 1.19379
CCL5 chemokine (C-C motif) ligand 5 1.19213
FKBP5 FK506 binding protein 5 1.19146
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.18981
CTSK cathepsin K 1.1862
EIF5 eukaryotic translation initiation factor 5 1.1862
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 1.1862
ADCY1 adenylate cyclase 1 (brain) 1.1862
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.18424
RGS4 regulator of G-protein signaling 4 1.18259
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.18126
THRB thyroid hormone receptor, beta 1.1786
ADORA1 adenosine A1 receptor 1.1786
PRPF38B pre-mRNA processing factor 38B 1.17761
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.17596
TUBB3 tubulin, beta 3 class III 1.17563
MMP9 matrix metallopeptidase 9 1.1753
IL1A interleukin 1, alpha 1.17497
FOSL1 FOS-like antigen 1 1.17366
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.17333
LEP leptin 1.17235
SCN2A sodium channel, voltage gated, type II alpha subunit 1.17034
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.17
LRRK2 leucine-rich repeat kinase 2 1.16967
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 1.16933
RAB3A RAB3A, member RAS oncogene family 1.16933
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.169
JUND jun D proto-oncogene 1.16866
INHA inhibin, alpha 1.16833
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.167
PNPLA4 patatin-like phospholipase domain containing 4 1.16567
RAD50 RAD50 homolog (S. cerevisiae) 1.16567
EPYC epiphycan 1.16567
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.16567
HSPA1A heat shock 70kDa protein 1A 1.16401
LPL lipoprotein lipase 1.16401
LAMB1 laminin, beta 1 1.16335
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.16335
HSPB1 heat shock 27kDa protein 1 1.16236
NRIP3 nuclear receptor interacting protein 3 1.1617
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.1617
REST RE1-silencing transcription factor 1.1617
TOR1A torsin family 1, member A (torsin A) 1.1617
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.16104
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.15899
CD9 CD9 molecule 1.15899
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.15865
MPO myeloperoxidase 1.1556
CBS cystathionine-beta-synthase 1.1556
PRODH2 proline dehydrogenase (oxidase) 2 1.15391
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 1.15391
DCXR dicarbonyl/L-xylulose reductase 1.15391
HSPA2 heat shock 70kDa protein 2 1.15256
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.15256
FOSL2 FOS-like antigen 2 1.15256
NOVA2 neuro-oncological ventral antigen 2 1.15122
ACTA2 actin, alpha 2, smooth muscle, aorta 1.14885
AR androgen receptor 1.14644
GADD45A growth arrest and DNA-damage-inducible, alpha 1.14575
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.14473
IVNS1ABP influenza virus NS1A binding protein 1.14438
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.14268
PPARA peroxisome proliferator-activated receptor alpha 1.14064
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.13997
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.13963
ADRB1 adrenoceptor beta 1 1.13963
PKLR pyruvate kinase, liver and RBC 1.13963
MANEA mannosidase, endo-alpha 1.13929
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.13929
BBS4 Bardet-Biedl syndrome 4 1.13895
CCNA2 cyclin A2 1.13862
CDC42 cell division cycle 42 1.13655
ERN1 endoplasmic reticulum to nucleus signaling 1 1.13655
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.13347
FNDC4 fibronectin type III domain containing 4 1.13245
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 1.13211
RGS8 regulator of G-protein signaling 8 1.13211
MED13L mediator complex subunit 13-like 1.13211
BTG3 BTG family, member 3 1.13109
HSPA4 heat shock 70kDa protein 4 1.13041
NPPB natriuretic peptide B 1.13041
PRKCA protein kinase C, alpha 1.12737
GSTM2 glutathione S-transferase mu 2 (muscle) 1.12737
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.12703
SNAP25 synaptosomal-associated protein, 25kDa 1.12703
EN1 engrailed homeobox 1 1.1253
PDE10A phosphodiesterase 10A 1.1253
ATG12 autophagy related 12 1.12495
UROS uroporphyrinogen III synthase 1.12461
YIPF4 Yip1 domain family, member 4 1.12461
TIGD2 tigger transposable element derived 2 1.12426
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.12426
LMCD1 LIM and cysteine-rich domains 1 1.12254
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.12254
IRAK1 interleukin-1 receptor-associated kinase 1 1.12254
DCLK1 doublecortin-like kinase 1 1.12254
SCN3A sodium channel, voltage gated, type III alpha subunit 1.11945
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.11911
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.11877
MT1E metallothionein 1E 1.11843
TFDP1 transcription factor Dp-1 1.11843
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.11843
ATF3 activating transcription factor 3 1.11843
PHB prohibitin 1.11843
MAPK4 mitogen-activated protein kinase 4 1.11843
PARK2 parkin RBR E3 ubiquitin protein ligase 1.11843
CALB1 calbindin 1, 28kDa 1.11843
PAIP1 poly(A) binding protein interacting protein 1 1.11843
NGF nerve growth factor (beta polypeptide) 1.11707
UNG uracil-DNA glycosylase 1.11571
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.11571
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.11536
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 1.11255
NPTX2 neuronal pentraxin II 1.11186
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 1.11186
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.11081
S100A6 S100 calcium binding protein A6 1.10699
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.10596
FNTB farnesyltransferase, CAAX box, beta 1.10562
CKB creatine kinase, brain 1.10424
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.10211
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.10175
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.10175
HTRA1 HtrA serine peptidase 1 1.10175
CREM cAMP responsive element modulator 1.1014
RNF44 ring finger protein 44 1.10069
OFD1 oral-facial-digital syndrome 1 1.10069
U2SURP U2 snRNP-associated SURP domain containing 1.10069
FOXO1 forkhead box O1 1.09857
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.09786
CGA glycoprotein hormones, alpha polypeptide 1.09786
TLR4 toll-like receptor 4 1.09681
KIAA1467 KIAA1467 1.09611
CNR1 cannabinoid receptor 1 (brain) 1.09576
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.09541
CRYAB crystallin, alpha B 1.09366
SGK1 serum/glucocorticoid regulated kinase 1 1.09366
HEXA hexosaminidase A (alpha polypeptide) 1.09332
CPN1 carboxypeptidase N, polypeptide 1 1.09297
HES5 hes family bHLH transcription factor 5 1.09297
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.09297
CLU clusterin 1.09047
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.09011
PNPLA2 patatin-like phospholipase domain containing 2 1.09011
COL6A1 collagen, type VI, alpha 1 1.09011
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 1.08975
CCND2 cyclin D2 1.08762
FGA fibrinogen alpha chain 1.08726
UCK2 uridine-cytidine kinase 2 1.0869
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.08619
RBL1 retinoblastoma-like 1 1.08619
ERBB2 erb-b2 receptor tyrosine kinase 2 1.08549
E2F1 E2F transcription factor 1 1.08549
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.08231
KLHL24 kelch-like family member 24 1.08231
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.08196
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.08196
DRD5 dopamine receptor D5 1.08126
EFNA2 ephrin-A2 1.07947
HSPE1 heat shock 10kDa protein 1 1.07947
SCAMP2 secretory carrier membrane protein 2 1.07947
TRIP11 thyroid hormone receptor interactor 11 1.07911
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.07875
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.0784
ATF4 activating transcription factor 4 1.07732
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.07589
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.07553
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.07553
PDE4A phosphodiesterase 4A, cAMP-specific 1.07553
EGR4 early growth response 4 1.07553
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.07553
ADRBK2 adrenergic, beta, receptor kinase 2 1.07553
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.07518
ANGPTL2 angiopoietin-like 2 1.07518
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.07518
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.07411
CPT1A carnitine palmitoyltransferase 1A (liver) 1.0734
FAM45A family with sequence similarity 45, member A 1.07234
VCAN versican 1.07128
DUT deoxyuridine triphosphatase 1.07128
PHIP pleckstrin homology domain interacting protein 1.06952
SOS1 son of sevenless homolog 1 (Drosophila) 1.06952
TF transferrin 1.06952
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 1.06917
RBBP5 retinoblastoma binding protein 5 1.06917
ZCCHC6 zinc finger, CCHC domain containing 6 1.06881
ARMC10 armadillo repeat containing 10 1.06881
CASP12 caspase 12 (gene/pseudogene) 1.06625
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.06442
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.06442
NSF N-ethylmaleimide-sensitive factor 1.06406
SYP synaptophysin 1.06406
ACBD3 acyl-CoA binding domain containing 3 1.06406
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.0637
TIMP2 TIMP metallopeptidase inhibitor 2 1.0637
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 1.06044
CRHBP corticotropin releasing hormone binding protein 1.05972
TUBB4A tubulin, beta 4A class IVa 1.05972
AKR1C3 aldo-keto reductase family 1, member C3 1.05972
GJC2 gap junction protein, gamma 2, 47kDa 1.05936
PDS5B PDS5 cohesin associated factor B 1.059
RASD2 RASD family, member 2 1.059
WRN Werner syndrome, RecQ helicase-like 1.059
LCMT2 leucine carboxyl methyltransferase 2 1.05864
RPL5 ribosomal protein L5 1.05828
ETFDH electron-transferring-flavoprotein dehydrogenase 1.05828
PER1 period circadian clock 1 1.05685
NREP neuronal regeneration related protein 1.05685
FOLR1 folate receptor 1 (adult) 1.05685
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.05573
COL1A2 collagen, type I, alpha 2 1.05386
EFHD1 EF-hand domain family, member D1 1.05312
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1.05312
RHOQ ras homolog family member Q 1.05312
TJP1 tight junction protein 1 1.05089
C11ORF24 chromosome 11 open reading frame 24 1.05052
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 1.05052
VWA9 von Willebrand factor A domain containing 9 1.04978
ACP5 acid phosphatase 5, tartrate resistant 1.04978
GATA4 GATA binding protein 4 1.04978
WDYHV1 WDYHV motif containing 1 1.04978
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.04941
BCAS4 breast carcinoma amplified sequence 4 1.04941
PRNP prion protein 1.04831
ADCY7 adenylate cyclase 7 1.04794
ADAM9 ADAM metallopeptidase domain 9 1.04757
VAT1 vesicle amine transport 1 1.04757
ARF1 ADP-ribosylation factor 1 1.04276
UBC ubiquitin C 1.04276
LITAF lipopolysaccharide-induced TNF factor 1.04276
RANBP1 RAN binding protein 1 1.04239
TRAP1 TNF receptor-associated protein 1 1.04239
CCNE1 cyclin E1 1.04201
REM2 RAS (RAD and GEM)-like GTP binding 2 1.04088
CRYZL1 crystallin, zeta (quinone reductase)-like 1 1.04051
GLTSCR2 glioma tumor suppressor candidate region gene 2 1.04051
PHF3 PHD finger protein 3 1.04051
MRPL20 mitochondrial ribosomal protein L20 1.04051
RPS25 ribosomal protein S25 1.04051
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.04014
RBBP9 retinoblastoma binding protein 9 1.04014
MARS2 methionyl-tRNA synthetase 2, mitochondrial 1.04014
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.03939
FASLG Fas ligand (TNF superfamily, member 6) 1.03939
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.03864
BID BH3 interacting domain death agonist 1.03752
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.03715
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03604
STIP1 stress-induced phosphoprotein 1 1.03604
WEE1 WEE1 G2 checkpoint kinase 1.03567
TYMS thymidylate synthetase 1.03493
CALR calreticulin 1.03382
PRKCZ protein kinase C, zeta 1.03271
TFAM transcription factor A, mitochondrial 1.03235
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.03235
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.03159
RAD1 RAD1 checkpoint DNA exonuclease 1.03159
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 1.03159
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.03159
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.03159
NRAP nebulin-related anchoring protein 1.03159
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.03122
WDR61 WD repeat domain 61 1.03122
HSPH1 heat shock 105kDa/110kDa protein 1 1.03122
RBM12B RNA binding motif protein 12B 1.03009
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.02933
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.02933
FADS1 fatty acid desaturase 1 1.02933
NOS3 nitric oxide synthase 3 (endothelial cell) 1.02746
ERBB4 erb-b2 receptor tyrosine kinase 4 1.02708
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.02671
MT2A metallothionein 2A 1.02596
ADRB2 adrenoceptor beta 2, surface 1.02596
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.02447
SCN2B sodium channel, voltage gated, type II beta subunit 1.02447
PRKCB protein kinase C, beta 1.0241
TIMP3 TIMP metallopeptidase inhibitor 3 1.0241
RAD51 RAD51 recombinase 1.0241
HSPG2 heparan sulfate proteoglycan 2 1.02373
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 1.02336
FKBP8 FK506 binding protein 8, 38kDa 1.02299
ANGPTL6 angiopoietin-like 6 1.02299
PKN2 protein kinase N2 1.02262
PITPNB phosphatidylinositol transfer protein, beta 1.02262
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.02225
HPN hepsin 1.02225
ETFB electron-transfer-flavoprotein, beta polypeptide 1.02225
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.02225
GCLM glutamate-cysteine ligase, modifier subunit 1.02151
COL1A1 collagen, type I, alpha 1 1.02077
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.01966
UBB ubiquitin B 1.01776
IFNA1 interferon, alpha 1 1.01776
ANXA2 annexin A2 1.01739
DDB2 damage-specific DNA binding protein 2, 48kDa 1.01739
RHOA ras homolog family member A 1.01739
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.01739
PLG plasminogen 1.01663
GRM8 glutamate receptor, metabotropic 8 1.01549
SEPT7 septin 7 1.01549
RAB8A RAB8A, member RAS oncogene family 1.01512
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.01512
NIN ninein (GSK3B interacting protein) 1.01474
PRMT7 protein arginine methyltransferase 7 1.01474
SNAP23 synaptosomal-associated protein, 23kDa 1.01474
AKT1S1 AKT1 substrate 1 (proline-rich) 1.01437
IL27RA interleukin 27 receptor, alpha 1.01437
KDM5A lysine (K)-specific demethylase 5A 1.01437
HDAC7 histone deacetylase 7 1.01437
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.01324
GLDC glycine dehydrogenase (decarboxylating) 1.01286
ZNF644 zinc finger protein 644 1.01286
WDR73 WD repeat domain 73 1.01249
RB1 retinoblastoma 1 1.01249
AZIN1 antizyme inhibitor 1 1.01249
TXNDC15 thioredoxin domain containing 15 1.01249
TMEM216 transmembrane protein 216 1.01137
FAM32A family with sequence similarity 32, member A 1.01137