Hypolipoproteinemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

257 genes co-occuring with the disease Hypolipoproteinemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 3.729
APOB apolipoprotein B 3.505
APOA1 apolipoprotein A-I 3.449
MTTP microsomal triglyceride transfer protein 3.4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 3.07
ANGPTL3 angiopoietin-like 3 2.99
LCAT lecithin-cholesterol acyltransferase 2.948
APOA2 apolipoprotein A-II 2.825
SAR1B secretion associated, Ras related GTPase 1B 2.813
LDLR low density lipoprotein receptor 2.797
CETP cholesteryl ester transfer protein, plasma 2.69
PCSK9 proprotein convertase subtilisin/kexin type 9 2.636
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.631
APOE apolipoprotein E 2.61
APOC3 apolipoprotein C-III 2.562
LIPG lipase, endothelial 2.559
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.54
SCARB1 scavenger receptor class B, member 1 2.535
APOC2 apolipoprotein C-II 2.52
PLTP phospholipid transfer protein 2.479
LIPC lipase, hepatic 2.461
LPL lipoprotein lipase 2.456
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 2.361
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.352
XPR1 xenotropic and polytropic retrovirus receptor 1 2.329
APOA5 apolipoprotein A-V 2.327
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.318
LPA lipoprotein, Lp(a) 2.311
TTPA tocopherol (alpha) transfer protein 2.308
LDLRAP1 low density lipoprotein receptor adaptor protein 1 2.29
APOA4 apolipoprotein A-IV 2.236
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.208
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.194
SREBF2 sterol regulatory element binding transcription factor 2 2.167
NPC1L1 NPC1-like 1 2.14
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.11
NPC1 Niemann-Pick disease, type C1 2.102
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 2.093
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.076
LMF1 lipase maturation factor 1 2.053
SREBF1 sterol regulatory element binding transcription factor 1 2.039
PNPLA3 patatin-like phospholipase domain containing 3 2.019
TM6SF2 transmembrane 6 superfamily member 2 2.003
DGAT1 diacylglycerol O-acyltransferase 1 1.989
APOC1 apolipoprotein C-I 1.984
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 1.97
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.963
LIPA lipase A, lysosomal acid, cholesterol esterase 1.938
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.932
PPARA peroxisome proliferator-activated receptor alpha 1.909
APOD apolipoprotein D 1.894
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.888
PON1 paraoxonase 1 1.871
INS insulin 1.856
NPC2 Niemann-Pick disease, type C2 1.84
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 1.827
DGAT2 diacylglycerol O-acyltransferase 2 1.792
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.791
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 1.784
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.776
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.761
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 1.718
PPARG peroxisome proliferator-activated receptor gamma 1.717
NIPSNAP3A nipsnap homolog 3A (C. elegans) 1.71
ALB albumin 1.708
SCARB2 scavenger receptor class B, member 2 1.707
CD36 CD36 molecule (thrombospondin receptor) 1.7
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.699
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 1.693
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.682
ANGPTL4 angiopoietin-like 4 1.668
DHCR7 7-dehydrocholesterol reductase 1.652
VLDLR very low density lipoprotein receptor 1.641
APOM apolipoprotein M 1.639
ANGPTL8 angiopoietin like 8 1.637
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.637
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 1.633
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 1.627
APOF apolipoprotein F 1.617
APTX aprataxin 1.606
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.588
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.557
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.556
UBIAD1 UbiA prenyltransferase domain containing 1 1.551
SOAT2 sterol O-acyltransferase 2 1.537
MYLIP myosin regulatory light chain interacting protein 1.527
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.526
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.524
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.52
MLXIPL MLX interacting protein-like 1.516
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.511
SCAP SREBF chaperone 1.5
APOC4 apolipoprotein C-IV 1.496
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.485
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 1.478
SOAT1 sterol O-acyltransferase 1 1.477
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.476
SORT1 sortilin 1 1.47
FXN frataxin 1.455
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 1.442
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 1.438
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.437
CLU clusterin 1.427
GCKR glucokinase (hexokinase 4) regulator 1.426
FABP1 fatty acid binding protein 1, liver 1.421
LIPE lipase, hormone-sensitive 1.39
AWAT1 acyl-CoA wax alcohol acyltransferase 1 1.378
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.373
IL1B interleukin 1, beta 1.366
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.364
PNLIP pancreatic lipase 1.364
HDLBP high density lipoprotein binding protein 1.363
CRP C-reactive protein, pentraxin-related 1.359
IGBP1 immunoglobulin (CD79A) binding protein 1 1.358
CP ceruloplasmin (ferroxidase) 1.356
OSBP oxysterol binding protein 1.349
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 1.348
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 1.341
IL6 interleukin 6 1.334
TRIB1 tribbles pseudokinase 1 1.332
STARD4 StAR-related lipid transfer (START) domain containing 4 1.33
DOCK7 dedicator of cytokinesis 7 1.327
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.326
LEP leptin 1.321
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.321
LRRIQ4 leucine-rich repeats and IQ motif containing 4 1.313
PLA2G10 phospholipase A2, group X 1.304
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.301
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 1.267
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.267
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.266
HCAR3 hydroxycarboxylic acid receptor 3 1.265
POLG polymerase (DNA directed), gamma 1.265
SACS sacsin molecular chaperone 1.263
PANK2 pantothenate kinase 2 1.261
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.256
GCG glucagon 1.255
TLR4 toll-like receptor 4 1.253
TNF tumor necrosis factor 1.252
DNAH8 dynein, axonemal, heavy chain 8 1.251
CAV1 caveolin 1, caveolae protein, 22kDa 1.247
LRP1 low density lipoprotein receptor-related protein 1 1.244
VCAM1 vascular cell adhesion molecule 1 1.238
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.238
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 1.237
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 1.237
TTC39B tetratricopeptide repeat domain 39B 1.236
PNPLA2 patatin-like phospholipase domain containing 2 1.235
INSIG1 insulin induced gene 1 1.233
ARL1 ADP-ribosylation factor-like 1 1.225
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.222
PEX7 peroxisomal biogenesis factor 7 1.22
INSR insulin receptor 1.22
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.213
OSBPL2 oxysterol binding protein-like 2 1.213
PNPLA5 patatin-like phospholipase domain containing 5 1.208
SAR1A secretion associated, Ras related GTPase 1A 1.204
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.203
APOL1 apolipoprotein L, 1 1.202
SC5D sterol-C5-desaturase 1.201
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.199
CPT1A carnitine palmitoyltransferase 1A (liver) 1.194
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.193
LPIN1 lipin 1 1.19
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.186
PHYH phytanoyl-CoA 2-hydroxylase 1.185
ADIPOQ adiponectin, C1Q and collagen domain containing 1.184
CROT carnitine O-octanoyltransferase 1.182
DYNLRB1 dynein, light chain, roadblock-type 1 1.18
CEL carboxyl ester lipase 1.175
ACTB actin, beta 1.174
CANX calnexin 1.173
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.173
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 1.168
COQ8A coenzyme Q8A 1.167
LYPLAL1 lysophospholipase-like 1 1.166
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.165
PPP1R3B protein phosphatase 1, regulatory subunit 3B 1.164
ACACA acetyl-CoA carboxylase alpha 1.162
CKM creatine kinase, muscle 1.16
CCL2 chemokine (C-C motif) ligand 2 1.157
CKMT1B creatine kinase, mitochondrial 1B 1.153
NIPSNAP3B nipsnap homolog 3B (C. elegans) 1.151
ARFRP1 ADP-ribosylation factor related protein 1 1.15
CKB creatine kinase, brain 1.15
PPARD peroxisome proliferator-activated receptor delta 1.149
SETX senataxin 1.144
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.143
ATP7B ATPase, Cu++ transporting, beta polypeptide 1.143
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.143
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.137
P4HB prolyl 4-hydroxylase, beta polypeptide 1.131
ARL4C ADP-ribosylation factor-like 4C 1.129
ABHD5 abhydrolase domain containing 5 1.128
ACLY ATP citrate lyase 1.128
SEC13 SEC13 homolog (S. cerevisiae) 1.127
ETV3L ets variant 3-like 1.127
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.127
PCSK6 proprotein convertase subtilisin/kexin type 6 1.126
GRAMD1B GRAM domain containing 1B 1.118
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.116
DHCR24 24-dehydrocholesterol reductase 1.115
CES1 carboxylesterase 1 1.104
LRP2 low density lipoprotein receptor-related protein 2 1.103
CD1D CD1d molecule 1.096
HPR haptoglobin-related protein 1.095
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.093
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.089
PXDNL peroxidasin-like 1.089
RHO rhodopsin 1.087
PXDN peroxidasin 1.087
GBA2 glucosidase, beta (bile acid) 2 1.086
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.085
TSC22D4 TSC22 domain family, member 4 1.084
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.083
APP amyloid beta (A4) precursor protein 1.083
OSBPL7 oxysterol binding protein-like 7 1.08
FASN fatty acid synthase 1.075
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.072
SLC35F5 solute carrier family 35, member F5 1.068
PEMT phosphatidylethanolamine N-methyltransferase 1.058
ICAM1 intercellular adhesion molecule 1 1.055
MRPS7 mitochondrial ribosomal protein S7 1.054
SQLE squalene epoxidase 1.053
INSIG2 insulin induced gene 2 1.052
HNF4A hepatocyte nuclear factor 4, alpha 1.05
NOS3 nitric oxide synthase 3 (endothelial cell) 1.05
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.047
STARD3 StAR-related lipid transfer (START) domain containing 3 1.04
APOH apolipoprotein H (beta-2-glycoprotein I) 1.039
NAXE NAD(P)HX epimerase 1.039
SEC24B SEC24 family member B 1.038
ACSL5 acyl-CoA synthetase long-chain family member 5 1.036
PDIA4 protein disulfide isomerase family A, member 4 1.036
CDC42 cell division cycle 42 1.036
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.034
PMM2 phosphomannomutase 2 1.033
TBP TATA box binding protein 1.03
IFNG interferon, gamma 1.03
MYO5B myosin VB 1.029
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.027
SIL1 SIL1 nucleotide exchange factor 1.025
ZNF202 zinc finger protein 202 1.02
NCEH1 neutral cholesterol ester hydrolase 1 1.019
CPT2 carnitine palmitoyltransferase 2 1.018
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.018
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.018
PLIN2 perilipin 2 1.018
PON3 paraoxonase 3 1.017
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.014
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.011
UGCG UDP-glucose ceramide glucosyltransferase 1.009
SELE selectin E 1.008
BCO1 beta-carotene oxygenase 1 1.006
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 1.004
PDZK1 PDZ domain containing 1 1.003
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.003