Hypopituitarism Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.|A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions. (Experimental Factor Ontology, EFO_0001380)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007018
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Genes

33 genes/proteins associated with the disease Hypopituitarism from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.88009
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.88009
PRL prolactin 2.88009
GH1 growth hormone 1 1.72158
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.39674
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.36677
MAPK3 mitogen-activated protein kinase 3 1.29996
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.29471
MAPK1 mitogen-activated protein kinase 1 1.29256
POMC proopiomelanocortin 1.2818
EGR3 early growth response 3 1.23806
PER1 period circadian clock 1 1.22853
VEGFA vascular endothelial growth factor A 1.21919
FAS Fas cell surface death receptor 1.21727
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.19379
TNF tumor necrosis factor 1.14954
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.14816
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.14644
NPPC natriuretic peptide C 1.12737
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.12703
CRH corticotropin releasing hormone 1.10527
TGFB1 transforming growth factor, beta 1 1.09786
SGK1 serum/glucocorticoid regulated kinase 1 1.0869
AKR1D1 aldo-keto reductase family 1, member D1 1.07482
CALB1 calbindin 1, 28kDa 1.06844
PCNA proliferating cell nuclear antigen 1.06771
IL1A interleukin 1, alpha 1.05757
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.05757
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.0561
FOS FBJ murine osteosarcoma viral oncogene homolog 1.02596
ART5 ADP-ribosyltransferase 5 1.02151
CCL2 chemokine (C-C motif) ligand 2 1.02077
FGF2 fibroblast growth factor 2 (basic) 1.01399