Hypopituitarism Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.|A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions. (Experimental Factor Ontology, EFO_0001380)
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Genes

12 genes involed in the disease Hypopituitarism from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LHX3 LIM homeobox 3 5.0
GLI2 GLI family zinc finger 2 5.0
GHRHR growth hormone releasing hormone receptor 5.0
SOX2 SRY (sex determining region Y)-box 2 5.0
PROKR2 prokineticin receptor 2 5.0
BTK Bruton agammaglobulinemia tyrosine kinase 5.0
OTX2 orthodenticle homeobox 2 5.0
GH1 growth hormone 1 5.0
POU1F1 POU class 1 homeobox 1 5.0
HESX1 HESX homeobox 1 5.0
LHX4 LIM homeobox 4 5.0
PROP1 PROP paired-like homeobox 1 5.0