Hypopituitarism Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.|A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions. (Experimental Factor Ontology, EFO_0001380)
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Genes

760 genes co-occuring with the disease Hypopituitarism in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
POMC proopiomelanocortin 3.651
PROP1 PROP paired-like homeobox 1 3.623
HESX1 HESX homeobox 1 3.514
POU1F1 POU class 1 homeobox 1 3.45
IGF1 insulin-like growth factor 1 (somatomedin C) 3.434
PRL prolactin 3.427
LHX4 LIM homeobox 4 3.407
GHRHR growth hormone releasing hormone receptor 3.365
ESX1 ESX homeobox 1 3.36
LHX3 LIM homeobox 3 3.315
GH1 growth hormone 1 3.231
GHRH growth hormone releasing hormone 3.146
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 3.023
SOX3 SRY (sex determining region Y)-box 3 2.966
GH2 growth hormone 2 2.912
AVP arginine vasopressin 2.889
GHR growth hormone receptor 2.853
RNPC3 RNA-binding region (RNP1, RRM) containing 3 2.819
TRH thyrotropin-releasing hormone 2.815
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 2.805
INS insulin 2.795
CSH2 chorionic somatomammotropin hormone 2 2.794
TBX19 T-box 19 2.779
OTX2 orthodenticle homeobox 2 2.769
IGLL5 immunoglobulin lambda-like polypeptide 5 2.709
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.683
PCNT pericentrin 2.681
SST somatostatin 2.677
TSHB thyroid stimulating hormone, beta 2.671
IGFBP3 insulin-like growth factor binding protein 3 2.656
PROKR2 prokineticin receptor 2 2.637
CRH corticotropin releasing hormone 2.615
MZB1 marginal zone B and B1 cell-specific protein 2.591
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 2.59
ORC4 origin recognition complex, subunit 4 2.517
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 2.501
GLI2 GLI family zinc finger 2 2.497
IGSF1 immunoglobulin superfamily, member 1 2.475
CD27 CD27 molecule 2.443
GCG glucagon 2.442
ORC6 origin recognition complex, subunit 6 2.414
GHSR growth hormone secretagogue receptor 2.363
JCHAIN joining chain of multimeric IgA and IgM 2.341
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.293
POC1A POC1 centriolar protein A 2.292
TCL1A T-cell leukemia/lymphoma 1A 2.229
ANOS1 anosmin 1 2.214
CD79A CD79a molecule, immunoglobulin-associated alpha 2.212
NKG7 natural killer cell granule protein 7 2.159
TRHR thyrotropin-releasing hormone receptor 2.158
FSHB follicle stimulating hormone, beta polypeptide 2.146
BTK Bruton agammaglobulinemia tyrosine kinase 2.141
CHD7 chromodomain helicase DNA binding protein 7 2.13
CEP152 centrosomal protein 152kDa 2.119
GNRHR gonadotropin-releasing hormone receptor 2.117
OXT oxytocin/neurophysin I prepropeptide 2.11
PITX1 paired-like homeodomain 1 2.108
CDT1 chromatin licensing and DNA replication factor 1 2.105
CD19 CD19 molecule 2.104
SHOX short stature homeobox 2.103
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.087
SOX2 SRY (sex determining region Y)-box 2 2.079
RTTN rotatin 2.073
GHRL ghrelin/obestatin prepropeptide 2.069
CD1C CD1c molecule 2.066
CNTLN centlein, centrosomal protein 2.063
SHBG sex hormone-binding globulin 2.058
CD274 CD274 molecule 2.057
SHH sonic hedgehog 2.049
FCRL5 Fc receptor-like 5 2.043
SIX3 SIX homeobox 3 2.041
TG thyroglobulin 2.037
GZMK granzyme K (granzyme 3; tryptase II) 2.034
AIP aryl hydrocarbon receptor interacting protein 2.032
TACR3 tachykinin receptor 3 2.02
PDCD1 programmed cell death 1 2.018
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 2.018
GPR101 G protein-coupled receptor 101 2.016
LARP7 La ribonucleoprotein domain family, member 7 2.016
TRAIP TRAF interacting protein 2.014
CD38 CD38 molecule 1.994
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.987
VPREB3 pre-B lymphocyte 3 1.979
CD3D CD3d molecule, delta (CD3-TCR complex) 1.978
CDC6 cell division cycle 6 1.976
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.974
LEP leptin 1.974
CD79B CD79b molecule, immunoglobulin-associated beta 1.969
SSTR5 somatostatin receptor 5 1.959
WDR4 WD repeat domain 4 1.954
CEP63 centrosomal protein 63kDa 1.949
SIX6 SIX homeobox 6 1.944
FGFR1 fibroblast growth factor receptor 1 1.941
GNLY granulysin 1.937
PITX2 paired-like homeodomain 2 1.937
IGF2 insulin-like growth factor 2 1.934
MKI67 marker of proliferation Ki-67 1.922
PROK2 prokineticin 2 1.921
CRIPT cysteine-rich PDZ-binding protein 1.916
TAC3 tachykinin 3 1.912
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.91
PRDM1 PR domain containing 1, with ZNF domain 1.903
CD4 CD4 molecule 1.897
MEN1 multiple endocrine neoplasia I 1.894
CD8A CD8a molecule 1.892
XBP1 X-box binding protein 1 1.887
FGF8 fibroblast growth factor 8 (androgen-induced) 1.885
KISS1R KISS1 receptor 1.885
CCR7 chemokine (C-C motif) receptor 7 1.883
AICDA activation-induced cytidine deaminase 1.881
GPR183 G protein-coupled receptor 183 1.88
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.871
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.857
TPO thyroid peroxidase 1.854
LYZ lysozyme 1.852
BCR breakpoint cluster region 1.851
CDC45 cell division cycle 45 1.844
SSTR2 somatostatin receptor 2 1.831
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.83
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.826
NKX2-1 NK2 homeobox 1 1.825
CDON cell adhesion associated, oncogene regulated 1.821
GMNN geminin, DNA replication inhibitor 1.815
CRP C-reactive protein, pentraxin-related 1.813
PNPLA6 patatin-like phospholipase domain containing 6 1.812
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 1.807
HLA-DRA major histocompatibility complex, class II, DR alpha 1.805
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.802
IL4R interleukin 4 receptor 1.802
MAGEL2 melanoma antigen family L2 1.798
ALB albumin 1.797
KISS1 KiSS-1 metastasis-suppressor 1.796
REN renin 1.791
AMH anti-Mullerian hormone 1.78
DONSON downstream neighbor of SON 1.776
BANK1 B-cell scaffold protein with ankyrin repeats 1 1.774
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 1.762
CSHL1 chorionic somatomammotropin hormone-like 1 1.762
GLI3 GLI family zinc finger 3 1.76
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.754
CD1E CD1e molecule 1.744
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 1.73
PLK4 polo-like kinase 4 1.729
WDR62 WD repeat domain 62 1.727
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 1.724
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.723
SDC1 syndecan 1 1.722
HNF1A HNF1 homeobox A 1.722
CD1A CD1a molecule 1.72
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.713
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.711
TP53 tumor protein p53 1.71
IL6 interleukin 6 1.707
CEP135 centrosomal protein 135kDa 1.707
METTL1 methyltransferase like 1 1.705
SYP synaptophysin 1.698
STIL SCL/TAL1 interrupting locus 1.697
CD5 CD5 molecule 1.694
IGFALS insulin-like growth factor binding protein, acid labile subunit 1.693
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.692
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.69
IL7R interleukin 7 receptor 1.689
PTH parathyroid hormone 1.689
CD1B CD1b molecule 1.688
IGSF10 immunoglobulin superfamily, member 10 1.686
BCL6 B-cell CLL/lymphoma 6 1.684
CD68 CD68 molecule 1.679
USP8 ubiquitin specific peptidase 8 1.675
GNAS GNAS complex locus 1.674
RGS13 regulator of G-protein signaling 13 1.674
PCSK1 proprotein convertase subtilisin/kexin type 1 1.673
CD8B CD8b molecule 1.669
BMP4 bone morphogenetic protein 4 1.666
TNF tumor necrosis factor 1.662
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.66
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.658
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12) 1.655
PAX6 paired box 6 1.654
FGFBP2 fibroblast growth factor binding protein 2 1.653
RPH3A rabphilin 3A 1.652
TBC1D32 TBC1 domain family, member 32 1.65
SUCO SUN domain containing ossification factor 1.642
IGFBP1 insulin-like growth factor binding protein 1 1.636
PAPPA2 pappalysin 2 1.633
IRF4 interferon regulatory factor 4 1.632
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 1.632
RGS18 regulator of G-protein signaling 18 1.631
CCDC141 coiled-coil domain containing 141 1.629
POC1B POC1 centriolar protein B 1.628
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.627
CD69 CD69 molecule 1.626
ZIC2 Zic family member 2 1.626
SRY sex determining region Y 1.625
FCRL4 Fc receptor-like 4 1.618
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.617
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.616
CXCR5 chemokine (C-X-C motif) receptor 5 1.612
PAX5 paired box 5 1.612
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.611
SEC11C SEC11 homolog C (S. cerevisiae) 1.609
CD1D CD1d molecule 1.608
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.603
IGLL1 immunoglobulin lambda-like polypeptide 1 1.6
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.597
CD86 CD86 molecule 1.596
SASS6 spindle assembly 6 homolog (C. elegans) 1.593
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.587
IL17RD interleukin 17 receptor D 1.587
MCM5 minichromosome maintenance complex component 5 1.586
CD24 CD24 molecule 1.578
SSTR1 somatostatin receptor 1 1.574
PRLR prolactin receptor 1.568
IYD iodotyrosine deiodinase 1.565
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.562
IGF1R insulin-like growth factor 1 receptor 1.562
STAT5B signal transducer and activator of transcription 5B 1.561
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 1.561
AIRE autoimmune regulator 1.561
AFP alpha-fetoprotein 1.56
CXCR4 chemokine (C-X-C motif) receptor 4 1.56
GPR161 G protein-coupled receptor 161 1.559
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.558
PDCD1LG2 programmed cell death 1 ligand 2 1.557
SSTR3 somatostatin receptor 3 1.553
IFNG interferon, gamma 1.552
TCF7 transcription factor 7 (T-cell specific, HMG-box) 1.552
IL1B interleukin 1, beta 1.548
NIN ninein (GSK3B interacting protein) 1.546
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.546
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 1.545
IFI6 interferon, alpha-inducible protein 6 1.545
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.544
FOXA2 forkhead box A2 1.543
SMC5 structural maintenance of chromosomes 5 1.541
OBSL1 obscurin-like 1 1.54
MCPH1 microcephalin 1 1.537
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.537
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.536
LHX2 LIM homeobox 2 1.535
ORC3 origin recognition complex, subunit 3 1.535
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.534
PTPRC protein tyrosine phosphatase, receptor type, C 1.532
CD72 CD72 molecule 1.52
NF1 neurofibromin 1 1.519
CUL7 cullin 7 1.517
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 1.514
FKBP11 FK506 binding protein 11, 19 kDa 1.511
FEZF1 FEZ family zinc finger 1 1.511
FOXP3 forkhead box P3 1.509
DMXL2 Dmx-like 2 1.509
NCAM1 neural cell adhesion molecule 1 1.504
CD83 CD83 molecule 1.501
CD80 CD80 molecule 1.5
TGIF1 TGFB-induced factor homeobox 1 1.499
ISL1 ISL LIM homeobox 1 1.496
CCDC8 coiled-coil domain containing 8 1.493
IFI44L interferon-induced protein 44-like 1.492
DRD2 dopamine receptor D2 1.49
INSR insulin receptor 1.489
KLRF1 killer cell lectin-like receptor subfamily F, member 1 1.489
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.485
LEF1 lymphoid enhancer-binding factor 1 1.48
ACE angiotensin I converting enzyme 1.479
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.479
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 1.478
CLEC9A C-type lectin domain family 9, member A 1.474
DNA2 DNA replication helicase/nuclease 2 1.469
IFNA1 interferon, alpha 1 1.469
TGFB1 transforming growth factor, beta 1 1.468
CD40 CD40 molecule, TNF receptor superfamily member 5 1.468
IL2 interleukin 2 1.467
TBX21 T-box 21 1.467
COG4 component of oligomeric golgi complex 4 1.465
CD28 CD28 molecule 1.461
ISG15 ISG15 ubiquitin-like modifier 1.461
ADIPOQ adiponectin, C1Q and collagen domain containing 1.459
MKRN3 makorin ring finger protein 3 1.458
CD40LG CD40 ligand 1.458
ESR1 estrogen receptor 1 1.456
CD22 CD22 molecule 1.455
DUSP1 dual specificity phosphatase 1 1.453
MC4R melanocortin 4 receptor 1.453
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.451
BGLAP bone gamma-carboxyglutamate (gla) protein 1.449
FLRT3 fibronectin leucine rich transmembrane protein 3 1.449
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.447
ZBTB32 zinc finger and BTB domain containing 32 1.446
TSHR thyroid stimulating hormone receptor 1.444
PRPF31 pre-mRNA processing factor 31 1.444
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.44
GATA2 GATA binding protein 2 1.44
GLI1 GLI family zinc finger 1 1.438
MME membrane metallo-endopeptidase 1.437
NCOR2 nuclear receptor corepressor 2 1.437
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 1.437
DUSP5 dual specificity phosphatase 5 1.436
BLNK B-cell linker 1.434
SNU13 small nuclear ribonucleoprotein 13 1.429
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.429
SPRY4 sprouty homolog 4 (Drosophila) 1.429
IL10 interleukin 10 1.429
ORC5 origin recognition complex, subunit 5 1.428
SOX10 SRY (sex determining region Y)-box 10 1.426
TBL1X transducin (beta)-like 1X-linked 1.425
RBBP8 retinoblastoma binding protein 8 1.425
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.425
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.421
MCM7 minichromosome maintenance complex component 7 1.42
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.42
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.419
DUOXA2 dual oxidase maturation factor 2 1.418
CD207 CD207 molecule, langerin 1.415
PXDN peroxidasin 1.414
SIM1 single-minded family bHLH transcription factor 1 1.414
ATRIP ATR interacting protein 1.414
CD163 CD163 molecule 1.413
KATNB1 katanin p80 (WD repeat containing) subunit B 1 1.413
CLEC4C C-type lectin domain family 4, member C 1.413
IFITM1 interferon induced transmembrane protein 1 1.413
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 1.412
USP48 ubiquitin specific peptidase 48 1.411
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.408
ORC1 origin recognition complex, subunit 1 1.406
SOX9 SRY (sex determining region Y)-box 9 1.405
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.403
PXDNL peroxidasin-like 1.398
STMN1 stathmin 1 1.391
C1QA complement component 1, q subcomponent, A chain 1.391
IFITM3 interferon induced transmembrane protein 3 1.388
INSL3 insulin-like 3 (Leydig cell) 1.387
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.386
IL3RA interleukin 3 receptor, alpha (low affinity) 1.381
ELL3 elongation factor RNA polymerase II-like 3 1.379
CHGA chromogranin A 1.378
AGRP agouti related neuropeptide 1.376
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.375
CEP192 centrosomal protein 192kDa 1.372
LGALS1 lectin, galactoside-binding, soluble, 1 1.371
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.37
PRPF3 pre-mRNA processing factor 3 1.37
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.369
FCRL3 Fc receptor-like 3 1.367
WDHD1 WD repeat and HMG-box DNA binding protein 1 1.364
VPREB1 pre-B lymphocyte 1 1.364
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.363
CTSW cathepsin W 1.363
CXCR3 chemokine (C-X-C motif) receptor 3 1.362
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.361
NDN necdin, melanoma antigen (MAGE) family member 1.361
IRS4 insulin receptor substrate 4 1.36
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.358
CEP120 centrosomal protein 120kDa 1.358
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.354
LEPR leptin receptor 1.353
CXCL13 chemokine (C-X-C motif) ligand 13 1.352
TDRD6 tudor domain containing 6 1.349
CLEC10A C-type lectin domain family 10, member A 1.349
FGF17 fibroblast growth factor 17 1.348
VWF von Willebrand factor 1.347
CD34 CD34 molecule 1.346
DNTT DNA nucleotidylexotransferase 1.346
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 1.345
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 1.345
FGF10 fibroblast growth factor 10 1.344
NEUROD1 neuronal differentiation 1 1.343
NPY neuropeptide Y 1.34
ACE2 angiotensin I converting enzyme 2 1.338
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.338
COL1A2 collagen, type I, alpha 2 1.335
FOXE1 forkhead box E1 1.331
HID1 HID1 domain containing 1.331
TMEM67 transmembrane protein 67 1.331
XCL2 chemokine (C motif) ligand 2 1.33
F2 coagulation factor II (thrombin) 1.329
RBM28 RNA binding motif protein 28 1.329
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.329
OTUD4 OTU deubiquitinase 4 1.325
MCM4 minichromosome maintenance complex component 4 1.325
FSHR follicle stimulating hormone receptor 1.325
XCL1 chemokine (C motif) ligand 1 1.325
PTCH1 patched 1 1.319
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.318
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 1.317
AQP2 aquaporin 2 (collecting duct) 1.317
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.315
SSR4 signal sequence receptor, delta 1.315
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.315
CCR6 chemokine (C-C motif) receptor 6 1.315
MEF2B myocyte enhancer factor 2B 1.314
ACTB actin, beta 1.311
FOXH1 forkhead box H1 1.311
ALMS1 Alstrom syndrome protein 1 1.306
CCRL2 chemokine (C-C motif) receptor-like 2 1.305
NDE1 nudE neurodevelopment protein 1 1.304
KIF7 kinesin family member 7 1.301
CCDC191 coiled-coil domain containing 191 1.297
GFAP glial fibrillary acidic protein 1.296
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.294
HYLS1 hydrolethalus syndrome 1 1.293
GATA3 GATA binding protein 3 1.291
NES nestin 1.291
FOS FBJ murine osteosarcoma viral oncogene homolog 1.291
INSM2 insulinoma-associated 2 1.29
PLD4 phospholipase D family, member 4 1.287
OFD1 oral-facial-digital syndrome 1 1.285
CCL5 chemokine (C-C motif) ligand 5 1.284
PTPRN protein tyrosine phosphatase, receptor type, N 1.283
POU2AF1 POU class 2 associating factor 1 1.282
NEUROD4 neuronal differentiation 4 1.279
OR6V1 olfactory receptor, family 6, subfamily V, member 1 1.278
EGFR epidermal growth factor receptor 1.276
ATR ATR serine/threonine kinase 1.274
S100A12 S100 calcium binding protein A12 1.274
LAG3 lymphocyte-activation gene 3 1.273
IFT172 intraflagellar transport 172 1.272
IRF8 interferon regulatory factor 8 1.271
KIAA0586 KIAA0586 1.268
IL2RA interleukin 2 receptor, alpha 1.266
IL1A interleukin 1, alpha 1.265
ZNF683 zinc finger protein 683 1.262
CEP164 centrosomal protein 164kDa 1.262
IHH indian hedgehog 1.26
ENO1 enolase 1, (alpha) 1.26
AR androgen receptor 1.259
EOMES eomesodermin 1.257
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.256
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 1.256
STAT1 signal transducer and activator of transcription 1, 91kDa 1.255
LIG4 ligase IV, DNA, ATP-dependent 1.253
IFNA2 interferon, alpha 2 1.252
ITGB7 integrin, beta 7 1.252
PLPP5 phospholipid phosphatase 5 1.251
NOTCH2 notch 2 1.251
PRPF4 pre-mRNA processing factor 4 1.249
PIGR polymeric immunoglobulin receptor 1.247
BCL2 B-cell CLL/lymphoma 2 1.244
IL4 interleukin 4 1.244
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.241
BLK BLK proto-oncogene, Src family tyrosine kinase 1.241
PCNA proliferating cell nuclear antigen 1.24
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.239
SCG2 secretogranin II 1.238
TPSAB1 tryptase alpha/beta 1 1.237
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.234
FGR FGR proto-oncogene, Src family tyrosine kinase 1.233
TBX3 T-box 3 1.233
PMEL premelanosome protein 1.233
OR2T29 olfactory receptor, family 2, subfamily T, member 29 1.233
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.23
CCL3 chemokine (C-C motif) ligand 3 1.228
HLA-A major histocompatibility complex, class I, A 1.227
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.227
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.226
JAK2 Janus kinase 2 1.225
MGMT O-6-methylguanine-DNA methyltransferase 1.222
CD2 CD2 molecule 1.221
JUN jun proto-oncogene 1.22
EMX1 empty spiracles homeobox 1 1.219
THRB thyroid hormone receptor, beta 1.216
RNF216 ring finger protein 216 1.216
CD84 CD84 molecule 1.215
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.213
CKB creatine kinase, brain 1.212
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.211
ALPP alkaline phosphatase, placental 1.211
CEP41 centrosomal protein 41kDa 1.211
APOB apolipoprotein B 1.209
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.208
PAX8 paired box 8 1.208
FOXP1 forkhead box P1 1.207
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.204
DUSP8 dual specificity phosphatase 8 1.204
STAT5A signal transducer and activator of transcription 5A 1.204
CCL2 chemokine (C-C motif) ligand 2 1.203
ICOS inducible T-cell co-stimulator 1.203
FOXL2 forkhead box L2 1.203
COL1A1 collagen, type I, alpha 1 1.203
CD180 CD180 molecule 1.201
IL32 interleukin 32 1.2
CC2D2A coiled-coil and C2 domain containing 2A 1.199
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.199
VCAN versican 1.199
ITM2B integral membrane protein 2B 1.199
S100B S100 calcium binding protein B 1.199
GLP1R glucagon-like peptide 1 receptor 1.197
CXCL9 chemokine (C-X-C motif) ligand 9 1.196
RPGRIP1L RPGRIP1-like 1.195
CD37 CD37 molecule 1.194
IFI27 interferon, alpha-inducible protein 27 1.194
VAX1 ventral anterior homeobox 1 1.193
CKM creatine kinase, muscle 1.192
CXCL8 chemokine (C-X-C motif) ligand 8 1.191
CKMT1B creatine kinase, mitochondrial 1B 1.19
CXCL12 chemokine (C-X-C motif) ligand 12 1.189
CNTRL centriolin 1.189
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.188
HHIP hedgehog interacting protein 1.188
RAG1 recombination activating gene 1 1.188
POTEF POTE ankyrin domain family, member F 1.188
HFE hemochromatosis 1.188
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.188
CEP290 centrosomal protein 290kDa 1.187
HAVCR2 hepatitis A virus cellular receptor 2 1.186
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.185
SLC30A10 solute carrier family 30, member 10 1.185
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.185
DBF4 DBF4 zinc finger 1.184
FGF18 fibroblast growth factor 18 1.183
CHEK1 checkpoint kinase 1 1.183
IFNA5 interferon, alpha 5 1.183
ENO2 enolase 2 (gamma, neuronal) 1.183
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.182
LHX1 LIM homeobox 1 1.182
OTX1 orthodenticle homeobox 1 1.179
HVCN1 hydrogen voltage gated channel 1 1.179
IFNA4 interferon, alpha 4 1.179
CCL4 chemokine (C-C motif) ligand 4 1.179
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 1.177
JUND jun D proto-oncogene 1.177
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.176
ZNF335 zinc finger protein 335 1.176
B2M beta-2-microglobulin 1.175
SOCS2 suppressor of cytokine signaling 2 1.174
APOE apolipoprotein E 1.173
FGF4 fibroblast growth factor 4 1.173
F3 coagulation factor III (thromboplastin, tissue factor) 1.171
IFNA17 interferon, alpha 17 1.17
IGFBP5 insulin-like growth factor binding protein 5 1.169
IER2 immediate early response 2 1.169
IL17A interleukin 17A 1.169
CGA glycoprotein hormones, alpha polypeptide 1.166
IFI44 interferon-induced protein 44 1.166
DLK1 delta-like 1 homolog (Drosophila) 1.165
EBF1 early B-cell factor 1 1.165
IFNA13 interferon, alpha 13 1.164
LY9 lymphocyte antigen 9 1.162
IFITM2 interferon induced transmembrane protein 2 1.16
FGFR3 fibroblast growth factor receptor 3 1.16
DERL3 derlin 3 1.16
IFNA7 interferon, alpha 7 1.159
IFNA16 interferon, alpha 16 1.159
IFNA10 interferon, alpha 10 1.158
ACAN aggrecan 1.158
IFNA21 interferon, alpha 21 1.158
IFNA8 interferon, alpha 8 1.158
IFNA14 interferon, alpha 14 1.158
IFNA6 interferon, alpha 6 1.157
SNRPN small nuclear ribonucleoprotein polypeptide N 1.154
PCSK2 proprotein convertase subtilisin/kexin type 2 1.152
WDR11 WD repeat domain 11 1.152
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 1.152
PF4 platelet factor 4 1.152
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.151
CNTROB centrobin, centrosomal BRCA2 interacting protein 1.151
ITM2C integral membrane protein 2C 1.147
WNT4 wingless-type MMTV integration site family, member 4 1.146
FAM90A1 family with sequence similarity 90, member A1 1.146
EGR1 early growth response 1 1.145
IFT80 intraflagellar transport 80 1.143
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.143
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.142
TCTN1 tectonic family member 1 1.14
CD70 CD70 molecule 1.138
CCDC74B coiled-coil domain containing 74B 1.137
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.136
CCL3L1 chemokine (C-C motif) ligand 3-like 1 1.135
IRF7 interferon regulatory factor 7 1.132
HLA-C major histocompatibility complex, class I, C 1.132
PRTN3 proteinase 3 1.132
GFRA2 GDNF family receptor alpha 2 1.131
ARL13B ADP-ribosylation factor-like 13B 1.131
TOP2A topoisomerase (DNA) II alpha 170kDa 1.13
H3C12 H3 clustered histone 12 1.129
TUBGCP6 tubulin, gamma complex associated protein 6 1.129
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.126
DCHS1 dachsous cadherin-related 1 1.125
FOXG1 forkhead box G1 1.125
ZCCHC8 zinc finger, CCHC domain containing 8 1.124
FGF3 fibroblast growth factor 3 1.123
CEP131 centrosomal protein 131kDa 1.121
H3-3B H3.3 histone B 1.121
CCL19 chemokine (C-C motif) ligand 19 1.12
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.12
CCND1 cyclin D1 1.117
ATM ATM serine/threonine kinase 1.117
PHC1 polyhomeotic homolog 1 (Drosophila) 1.115
FDCSP follicular dendritic cell secreted protein 1.114
C1QB complement component 1, q subcomponent, B chain 1.114
OR10T2 olfactory receptor, family 10, subfamily T, member 2 1.113
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.111
NKX2-2 NK2 homeobox 2 1.111
OR3A1 olfactory receptor, family 3, subfamily A, member 1 1.109
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.109
MC3R melanocortin 3 receptor 1.108
EGF epidermal growth factor 1.108
HOPX HOP homeobox 1.108
HBB hemoglobin, beta 1.108
FGF7 fibroblast growth factor 7 1.108
S100A4 S100 calcium binding protein A4 1.105
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.105
MNDA myeloid cell nuclear differentiation antigen 1.105
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.105
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.105
FGF9 fibroblast growth factor 9 1.103
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.102
APOC1 apolipoprotein C-I 1.102
CABLES1 Cdk5 and Abl enzyme substrate 1 1.102
FCGBP Fc fragment of IgG binding protein 1.101
FGF20 fibroblast growth factor 20 1.101
H3C13 H3 clustered histone 13 1.101
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.1
CXCR6 chemokine (C-X-C motif) receptor 6 1.1
CD200 CD200 molecule 1.1
TUBA1A tubulin, alpha 1a 1.099
BBS4 Bardet-Biedl syndrome 4 1.098
SLAMF7 SLAM family member 7 1.098
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.098
SOX4 SRY (sex determining region Y)-box 4 1.096
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.095
RAB2A RAB2A, member RAS oncogene family 1.094
IL21R interleukin 21 receptor 1.094
KRAS Kirsten rat sarcoma viral oncogene homolog 1.094
OR10K1 olfactory receptor, family 10, subfamily K, member 1 1.093
AHI1 Abelson helper integration site 1 1.092
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.092
COL3A1 collagen, type III, alpha 1 1.091
AVPR1B arginine vasopressin receptor 1B 1.09
WFS1 Wolfram syndrome 1 (wolframin) 1.09
MCM10 minichromosome maintenance complex component 10 1.089
ISG20 interferon stimulated exonuclease gene 20kDa 1.089
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 1.088
KIAA0753 KIAA0753 1.087
CDKN2A cyclin-dependent kinase inhibitor 2A 1.087
FGF6 fibroblast growth factor 6 1.087
H3-5 H3.5 histone 1.087
PTTG1 pituitary tumor-transforming 1 1.086
H3-4 H3.4 histone, cluster member 1.086
CETN2 centrin, EF-hand protein, 2 1.082
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.082
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.082
LGALS3 lectin, galactoside-binding, soluble, 3 1.082
KRT8 keratin 8, type II 1.082
AKAP9 A kinase (PRKA) anchor protein 9 1.082
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.081
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.08
FGF22 fibroblast growth factor 22 1.08
FGF5 fibroblast growth factor 5 1.079
C1QC complement component 1, q subcomponent, C chain 1.079
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.078
FGF16 fibroblast growth factor 16 1.078
IRS1 insulin receptor substrate 1 1.078
MCM6 minichromosome maintenance complex component 6 1.076
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.076
KNL1 kinetochore scaffold 1 1.076
PRPF8 pre-mRNA processing factor 8 1.075
TP53BP1 tumor protein p53 binding protein 1 1.075
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 1.073
NOTCH1 notch 1 1.073
ICAM1 intercellular adhesion molecule 1 1.073
TMEM231 transmembrane protein 231 1.071
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.07
C1ORF54 chromosome 1 open reading frame 54 1.068
AIM2 absent in melanoma 2 1.068
ERBB2 erb-b2 receptor tyrosine kinase 2 1.066
FGFR2 fibroblast growth factor receptor 2 1.066
SLC44A4 solute carrier family 44, member 4 1.065
KLK3 kallikrein-related peptidase 3 1.065
PPARG peroxisome proliferator-activated receptor gamma 1.065
TUBB2B tubulin, beta 2B class IIb 1.065
ASPH aspartate beta-hydroxylase 1.065
DUOX2 dual oxidase 2 1.063
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.063
GZMM granzyme M (lymphocyte met-ase 1) 1.062
ANKRD33 ankyrin repeat domain 33 1.061
CXCL10 chemokine (C-X-C motif) ligand 10 1.061
IFI30 interferon, gamma-inducible protein 30 1.061
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.06
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.059
MX1 MX dynamin-like GTPase 1 1.058
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.057
KRT18 keratin 18, type I 1.057
ZNF316 zinc finger protein 316 1.055
DPP4 dipeptidyl-peptidase 4 1.055
NPAP1 nuclear pore associated protein 1 1.053
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.052
IL7 interleukin 7 1.05
HMGA2 high mobility group AT-hook 2 1.049
DUSP6 dual specificity phosphatase 6 1.048
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.048
EPCAM epithelial cell adhesion molecule 1.048
NODAL nodal growth differentiation factor 1.048
CD160 CD160 molecule 1.047
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 1.047
OR2M4 olfactory receptor, family 2, subfamily M, member 4 1.046
MCM3 minichromosome maintenance complex component 3 1.046
SOS1 son of sevenless homolog 1 (Drosophila) 1.045
PECAM1 platelet/endothelial cell adhesion molecule 1 1.044
CENPF centromere protein F, 350/400kDa 1.043
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.043
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.043
LHB luteinizing hormone beta polypeptide 1.04
HCRT hypocretin (orexin) neuropeptide precursor 1.04
TXNRD2 thioredoxin reductase 2 1.04
SH2B1 SH2B adaptor protein 1 1.039
ACTA2 actin, alpha 2, smooth muscle, aorta 1.037
GCK glucokinase (hexokinase 4) 1.037
ANXA1 annexin A1 1.036
CREB3L2 cAMP responsive element binding protein 3-like 2 1.034
FCRLA Fc receptor-like A 1.033
TCTN3 tectonic family member 3 1.033
SNED1 sushi, nidogen and EGF-like domains 1 1.031
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.031
NPHP1 nephronophthisis 1 (juvenile) 1.031
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.03
CD44 CD44 molecule (Indian blood group) 1.029
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.028
GINS4 GINS complex subunit 4 (Sld5 homolog) 1.028
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.026
SOX5 SRY (sex determining region Y)-box 5 1.026
DISP1 dispatched homolog 1 (Drosophila) 1.026
CIITA class II, major histocompatibility complex, transactivator 1.026
FGF2 fibroblast growth factor 2 (basic) 1.025
CRTAM cytotoxic and regulatory T cell molecule 1.025
POU3F4 POU class 3 homeobox 4 1.025
PIBF1 progesterone immunomodulatory binding factor 1 1.024
YBX3 Y box binding protein 3 1.022
MARCKSL1 MARCKS-like 1 1.021
DUSP2 dual specificity phosphatase 2 1.02
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.02
BTLA B and T lymphocyte associated 1.018
H4C6 H4 clustered histone 6 1.017
PMM2 phosphomannomutase 2 1.017
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.016
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.016
CD52 CD52 molecule 1.015
BDNF brain-derived neurotrophic factor 1.014
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.014
MKS1 Meckel syndrome, type 1 1.014
MAP2K1 mitogen-activated protein kinase kinase 1 1.013
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.013
APOA1 apolipoprotein A-I 1.011
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.011
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.011
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.01
TRIM8 tripartite motif containing 8 1.01
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.01
PTEN phosphatase and tensin homolog 1.009
SOX21 SRY (sex determining region Y)-box 21 1.009
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.008
ZEB2 zinc finger E-box binding homeobox 2 1.008
PLVAP plasmalemma vesicle associated protein 1.006
CST7 cystatin F (leukocystatin) 1.005
NPHP4 nephronophthisis 4 1.005
RAB3D RAB3D, member RAS oncogene family 1.005
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.002
GLI4 GLI family zinc finger 4 1.002
JAG1 jagged 1 1.001
CASR calcium-sensing receptor 1.001
TOX thymocyte selection-associated high mobility group box 1.0
XYLT1 xylosyltransferase I 1.0