Hypotension, Orthostatic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007024
Similar Terms
Downloads & Tools

Genes

146 genes/proteins associated with the disease Hypotension, Orthostatic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
OPRM1 opioid receptor, mu 1 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
OPRD1 opioid receptor, delta 1 2.88009
REN renin 2.44806
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.41712
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.38539
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.33053
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.32279
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.30242
FOS FBJ murine osteosarcoma viral oncogene homolog 2.28606
PRL prolactin 2.20048
TNF tumor necrosis factor 2.14469
BCL2 B-cell CLL/lymphoma 2 2.07902
CAT catalase 2.0725
MAPK1 mitogen-activated protein kinase 1 2.05645
MAPK3 mitogen-activated protein kinase 3 2.03078
BAX BCL2-associated X protein 1.98338
AVP arginine vasopressin 1.97303
NPY neuropeptide Y 1.97082
NPPA natriuretic peptide A 1.97067
IL6 interleukin 6 1.93659
ADRB1 adrenoceptor beta 1 1.93552
DRD2 dopamine receptor D2 1.90787
BDNF brain-derived neurotrophic factor 1.88523
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.88159
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.87211
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.86585
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.85468
ADRB2 adrenoceptor beta 2, surface 1.82919
INS insulin 1.8172
ADRA1A adrenoceptor alpha 1A 1.77277
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.75361
VEGFA vascular endothelial growth factor A 1.71338
ADRA1D adrenoceptor alpha 1D 1.70988
FASLG Fas ligand (TNF superfamily, member 6) 1.70326
CRH corticotropin releasing hormone 1.69846
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.69805
TGFB1 transforming growth factor, beta 1 1.69405
TH tyrosine hydroxylase 1.67333
EGR1 early growth response 1 1.63788
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.63743
NOS2 nitric oxide synthase 2, inducible 1.63541
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.63072
NPPB natriuretic peptide B 1.6199
EDN1 endothelin 1 1.61944
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.60454
C10ORF10 chromosome 10 open reading frame 10 1.59404
DRD1 dopamine receptor D1 1.59264
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.59007
NOS3 nitric oxide synthase 3 (endothelial cell) 1.58018
MMP2 matrix metallopeptidase 2 1.57806
INHBE inhibin, beta E 1.5745
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.56484
ADRA1B adrenoceptor alpha 1B 1.55206
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.54475
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.54232
IL1B interleukin 1, beta 1.52938
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.52338
POMC proopiomelanocortin 1.51708
TAC1 tachykinin, precursor 1 1.50979
SOD2 superoxide dismutase 2, mitochondrial 1.50675
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.49941
CCL2 chemokine (C-C motif) ligand 2 1.48941
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.4522
MAOB monoamine oxidase B 1.45036
MMP9 matrix metallopeptidase 9 1.44927
CREB1 cAMP responsive element binding protein 1 1.44029
FAS Fas cell surface death receptor 1.40486
HMOX1 heme oxygenase 1 1.40429
NUPR1 nuclear protein, transcriptional regulator, 1 1.39226
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.38974
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.38441
ADRA2A adrenoceptor alpha 2A 1.37389
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.37389
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.36476
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.35386
GSTP1 glutathione S-transferase pi 1 1.34694
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.3382
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.32935
GH1 growth hormone 1 1.32221
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.31686
COMT catechol-O-methyltransferase 1.31566
CALCA calcitonin-related polypeptide alpha 1.30635
JUN jun proto-oncogene 1.30269
HPN hepsin 1.28858
OXT oxytocin/neurophysin I prepropeptide 1.28518
TAGLN transgelin 1.28241
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.28149
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.27905
G6PD glucose-6-phosphate dehydrogenase 1.27751
IL10 interleukin 10 1.26607
FNDC4 fibronectin type III domain containing 4 1.26452
ADRB3 adrenoceptor beta 3 1.25838
CYCS cytochrome c, somatic 1.25338
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.23584
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.23137
EPO erythropoietin 1.23106
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.23074
IL1A interleukin 1, alpha 1.22664
FABP1 fatty acid binding protein 1, liver 1.21663
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.20946
DDIT3 DNA-damage-inducible transcript 3 1.19445
CXCL8 chemokine (C-X-C motif) ligand 8 1.19379
DRD3 dopamine receptor D3 1.19246
SOD1 superoxide dismutase 1, soluble 1.19047
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.18685
MAOA monoamine oxidase A 1.18685
FN1 fibronectin 1 1.18391
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.17431
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.17268
GNAS GNAS complex locus 1.16203
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.15391
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.14919
ACE angiotensin I converting enzyme 1.14713
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.14064
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.13963
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.13655
PRKCD protein kinase C, delta 1.13109
IL2 interleukin 2 1.12973
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.12838
LPL lipoprotein lipase 1.12838
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.12599
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.12048
TP53 tumor protein p53 1.11639
IGF1 insulin-like growth factor 1 (somatomedin C) 1.11186
BCL2L1 BCL2-like 1 1.10562
LDLR low density lipoprotein receptor 1.09927
COL1A1 collagen, type I, alpha 1 1.08337
MAPK14 mitogen-activated protein kinase 14 1.08019
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.07983
CREM cAMP responsive element modulator 1.07305
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.07057
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.06333
GJA1 gap junction protein, alpha 1, 43kDa 1.059
F3 coagulation factor III (thromboplastin, tissue factor) 1.05828
APP amyloid beta (A4) precursor protein 1.05721
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.0561
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.05312
CCL5 chemokine (C-C motif) ligand 5 1.05237
CHGA chromogranin A 1.04757
MCL1 myeloid cell leukemia 1 1.04757
SREBF1 sterol regulatory element binding transcription factor 1 1.04574
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.03752
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.03345
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.02634
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.02522