Hypotensive episode_Renal Tissue_GSE2401 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2401
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Genes

600 genes differentially expressed during Hypotensive episode_Renal Tissue_GSE2401 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3.78189
WBP1L WW domain binding protein 1-like 3.71736
TMEM140 transmembrane protein 140 3.60407
UBXN4 UBX domain protein 4 3.55806
FBXO31 F-box protein 31 3.38585
DDT D-dopachrome tautomerase 3.2975
GSK3A glycogen synthase kinase 3 alpha 3.25641
CHKB choline kinase beta 3.22929
SPRYD7 SPRY domain containing 7 3.14253
MSRB1 methionine sulfoxide reductase B1 3.07393
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 3.03372
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 2.98337
KLF15 Kruppel-like factor 15 2.94705
RPL31 ribosomal protein L31 2.91557
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.84391
YPEL5 yippee-like 5 (Drosophila) 2.83597
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 2.79863
PBLD phenazine biosynthesis-like protein domain containing 2.7827
GPR146 G protein-coupled receptor 146 2.76611
HDGF hepatoma-derived growth factor 2.71222
BCAP31 B-cell receptor-associated protein 31 2.66561
MAP4 microtubule-associated protein 4 2.59153
CRYL1 crystallin, lambda 1 2.58029
TSC22D3 TSC22 domain family, member 3 2.56597
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.51711
RTN4IP1 reticulon 4 interacting protein 1 2.50018
MFN1 mitofusin 1 2.48606
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 2.47358
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 2.4557
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 2.43581
MINK1 misshapen-like kinase 1 2.42422
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.42307
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.42262
FAM35A family with sequence similarity 35, member A 2.41294
TST thiosulfate sulfurtransferase (rhodanese) 2.40497
GHITM growth hormone inducible transmembrane protein 2.39785
SRA1 steroid receptor RNA activator 1 2.38617
RPL38 ribosomal protein L38 2.38334
ALAD aminolevulinate dehydratase 2.36531
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2.3598
RAB24 RAB24, member RAS oncogene family 2.35001
RPL5 ribosomal protein L5 2.34893
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 2.33044
RPL3 ribosomal protein L3 2.3249
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.32169
RPL18A ribosomal protein L18a 2.29226
DNAL4 dynein, axonemal, light chain 4 2.28432
LAMA1 laminin, alpha 1 2.27025
GNS glucosamine (N-acetyl)-6-sulfatase 2.24815
LARS leucyl-tRNA synthetase 2.24648
GABARAPL1 GABA(A) receptor-associated protein like 1 2.24509
AK3 adenylate kinase 3 2.24305
STX18 syntaxin 18 2.2349
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.21554
RNASEH1 ribonuclease H1 2.19225
NDRG1 N-myc downstream regulated 1 2.1738
RPS28 ribosomal protein S28 2.16956
ETHE1 ethylmalonic encephalopathy 1 2.1572
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 2.11882
PSENEN presenilin enhancer gamma secretase subunit 2.10859
CYC1 cytochrome c-1 2.07769
ZFR zinc finger RNA binding protein 2.05312
NUB1 negative regulator of ubiquitin-like proteins 1 2.04478
USP24 ubiquitin specific peptidase 24 2.04159
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.04048
NTPCR nucleoside-triphosphatase, cancer-related 2.03155
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.02117
XDH xanthine dehydrogenase 2.01784
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.01632
NDEL1 nudE neurodevelopment protein 1-like 1 2.01571
CD320 CD320 molecule 2.00811
GSTZ1 glutathione S-transferase zeta 1 1.99551
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 1.99135
NUBP2 nucleotide binding protein 2 1.97946
MRPS18B mitochondrial ribosomal protein S18B 1.97588
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.97533
PSME4 proteasome (prosome, macropain) activator subunit 4 1.96796
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 1.96057
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 1.95766
DHPS deoxyhypusine synthase 1.9522
TBC1D14 TBC1 domain family, member 14 1.94631
RPS20 ribosomal protein S20 1.9375
TMED9 transmembrane emp24 protein transport domain containing 9 1.93293
DYM dymeclin 1.92686
UCK1 uridine-cytidine kinase 1 1.92105
PRDX1 peroxiredoxin 1 1.91493
TRIM32 tripartite motif containing 32 1.9142
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 1.91151
PGRMC2 progesterone receptor membrane component 2 1.90242
ETFB electron-transfer-flavoprotein, beta polypeptide 1.9019
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.89628
EXOC3 exocyst complex component 3 1.88365
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.88137
ZFAND2A zinc finger, AN1-type domain 2A 1.88014
ABLIM1 actin binding LIM protein 1 1.87762
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 1.87032
NPHP1 nephronophthisis 1 (juvenile) 1.84874
MRPS23 mitochondrial ribosomal protein S23 1.84413
ERLIN1 ER lipid raft associated 1 1.83201
TBRG4 transforming growth factor beta regulator 4 1.82621
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 1.8228
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.82004
RPS11 ribosomal protein S11 1.81939
ZFP36L1 ZFP36 ring finger protein-like 1 1.816
MRPL19 mitochondrial ribosomal protein L19 1.80722
TMBIM1 transmembrane BAX inhibitor motif containing 1 1.80547
ACP6 acid phosphatase 6, lysophosphatidic 1.79419
USPL1 ubiquitin specific peptidase like 1 1.79152
UBC ubiquitin C 1.78993
PREPL prolyl endopeptidase-like 1.78992
TRAK1 trafficking protein, kinesin binding 1 1.7726
KRT8 keratin 8, type II 1.77151
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.76867
CLDN7 claudin 7 1.75821
FLOT2 flotillin 2 1.75706
FUCA1 fucosidase, alpha-L- 1, tissue 1.7544
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.74521
USP11 ubiquitin specific peptidase 11 1.74112
RHBDD2 rhomboid domain containing 2 1.73926
MAN1B1 mannosidase, alpha, class 1B, member 1 1.7326
NQO1 NAD(P)H dehydrogenase, quinone 1 1.73057
SCYL2 SCY1-like 2 (S. cerevisiae) 1.73052
SUN2 Sad1 and UNC84 domain containing 2 1.72504
RPS25 ribosomal protein S25 1.72263
GARS glycyl-tRNA synthetase 1.72007
HEXA hexosaminidase A (alpha polypeptide) 1.71763
RPL35 ribosomal protein L35 1.71393
GLTSCR2 glioma tumor suppressor candidate region gene 2 1.68721
IGFBP1 insulin-like growth factor binding protein 1 1.68457
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.67505
STAU2 staufen double-stranded RNA binding protein 2 1.67079
CA12 carbonic anhydrase XII 1.66799
TESK2 testis-specific kinase 2 1.66682
DDIT3 DNA-damage-inducible transcript 3 1.66445
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.66439
IGF1R insulin-like growth factor 1 receptor 1.66345
ITGB5 integrin, beta 5 1.65423
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.64268
LONP2 lon peptidase 2, peroxisomal 1.64215
AKAP13 A kinase (PRKA) anchor protein 13 1.63565
ORC2 origin recognition complex, subunit 2 1.63196
PPP1R13B protein phosphatase 1, regulatory subunit 13B 1.63137
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.63049
EIF3C eukaryotic translation initiation factor 3, subunit C 1.62043
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.6184
SIN3B SIN3 transcription regulator family member B 1.61796
COASY CoA synthase 1.61021
DENND3 DENN/MADD domain containing 3 1.60788
GADD45B growth arrest and DNA-damage-inducible, beta 1.60228
PTGES2 prostaglandin E synthase 2 1.59426
NPC2 Niemann-Pick disease, type C2 1.5939
DOPEY2 dopey family member 2 1.59069
MECR mitochondrial trans-2-enoyl-CoA reductase 1.58993
DNPEP aspartyl aminopeptidase 1.58231
NT5E 5'-nucleotidase, ecto (CD73) 1.5742
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.57211
SELENBP1 selenium binding protein 1 1.57025
PRPF8 pre-mRNA processing factor 8 1.55948
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.55627
GSTA3 glutathione S-transferase alpha 3 1.55375
FNTB farnesyltransferase, CAAX box, beta 1.55197
PNPLA7 patatin-like phospholipase domain containing 7 1.54974
DHDDS dehydrodolichyl diphosphate synthase 1.54527
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.5451
STIM1 stromal interaction molecule 1 1.54478
TACC2 transforming, acidic coiled-coil containing protein 2 1.54467
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.54454
SETD2 SET domain containing 2 1.54275
TSPO translocator protein (18kDa) 1.53597
COTL1 coactosin-like F-actin binding protein 1 1.5278
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.52675
GNB5 guanine nucleotide binding protein (G protein), beta 5 1.52081
CNPPD1 cyclin Pas1/PHO80 domain containing 1 1.5203
RPL10A ribosomal protein L10a 1.51821
ZNF787 zinc finger protein 787 1.51606
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.51605
GCHFR GTP cyclohydrolase I feedback regulator 1.51359
SHISA5 shisa family member 5 1.51293
RPS4Y1 ribosomal protein S4, Y-linked 1 1.51165
TXN thioredoxin 1.50234
NRD1 nardilysin (N-arginine dibasic convertase) 1.50013
TNRC6A trinucleotide repeat containing 6A 1.49618
EIF3D eukaryotic translation initiation factor 3, subunit D 1.48153
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 1.47969
DMBT1 deleted in malignant brain tumors 1 1.46563
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.45789
TMED4 transmembrane emp24 protein transport domain containing 4 1.45071
FAM168A family with sequence similarity 168, member A 1.44777
FBXW5 F-box and WD repeat domain containing 5 1.44135
ACADVL acyl-CoA dehydrogenase, very long chain 1.43991
SRPR signal recognition particle receptor (docking protein) 1.43315
SAE1 SUMO1 activating enzyme subunit 1 1.42956
FDX1 ferredoxin 1 1.42935
CIZ1 CDKN1A interacting zinc finger protein 1 1.42703
LARP1 La ribonucleoprotein domain family, member 1 1.4245
CCNG1 cyclin G1 1.41851
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.41632
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.41403
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.41314
CNN3 calponin 3, acidic 1.41307
UPB1 ureidopropionase, beta 1.41191
RIPK4 receptor-interacting serine-threonine kinase 4 1.41152
GCDH glutaryl-CoA dehydrogenase 1.40736
BDH2 3-hydroxybutyrate dehydrogenase, type 2 1.40703
CHKA choline kinase alpha 1.40689
C1QBP complement component 1, q subcomponent binding protein 1.40521
ARL4A ADP-ribosylation factor-like 4A 1.40506
RNF216 ring finger protein 216 1.40441
FAIM Fas apoptotic inhibitory molecule 1.4035
AS3MT arsenite methyltransferase 1.40329
TBCB tubulin folding cofactor B 1.39983
MEPCE methylphosphate capping enzyme 1.39746
MCRS1 microspherule protein 1 1.39683
ELAC2 elaC ribonuclease Z 2 1.39638
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 1.39564
OPTN optineurin 1.39409
DCAF7 DDB1 and CUL4 associated factor 7 1.38802
MRPL17 mitochondrial ribosomal protein L17 1.38757
AASS aminoadipate-semialdehyde synthase 1.38455
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 1.37604
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.37582
HYAL3 hyaluronoglucosaminidase 3 1.3708
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 1.37005
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.36528
LITAF lipopolysaccharide-induced TNF factor 1.35915
GSTP1 glutathione S-transferase pi 1 1.35817
LRRC59 leucine rich repeat containing 59 1.35782
MARK3 MAP/microtubule affinity-regulating kinase 3 1.35748
KIFC3 kinesin family member C3 1.35454
VPS9D1 VPS9 domain containing 1 1.35415
PCID2 PCI domain containing 2 1.35273
PDZK1IP1 PDZK1 interacting protein 1 1.34961
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.34535
TRAPPC2L trafficking protein particle complex 2-like 1.34264
PTDSS1 phosphatidylserine synthase 1 1.34243
MGP matrix Gla protein 1.33804
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.3354
ZFYVE27 zinc finger, FYVE domain containing 27 1.33519
ECH1 enoyl CoA hydratase 1, peroxisomal 1.33458
SUMF1 sulfatase modifying factor 1 1.33354
HBP1 HMG-box transcription factor 1 1.33098
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.32712
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.32673
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.32227
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.32215
CST3 cystatin C 1.32016
SAMD11 sterile alpha motif domain containing 11 1.31798
CPQ carboxypeptidase Q 1.31784
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.31661
RPS8 ribosomal protein S8 1.31477
PDRG1 p53 and DNA-damage regulated 1 1.3131
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.3103
GLA galactosidase, alpha 1.3088
HTRA2 HtrA serine peptidase 2 1.30832
F3 coagulation factor III (thromboplastin, tissue factor) 1.3076
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.30732
XBP1 X-box binding protein 1 1.3047
ZFAND5 zinc finger, AN1-type domain 5 1.30037
PYGL phosphorylase, glycogen, liver 1.29873
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 1.29834
PALM3 paralemmin 3 1.29711
UBXN6 UBX domain protein 6 1.29016
MPV17L2 MPV17 mitochondrial membrane protein-like 2 1.28868
SEC14L1 SEC14-like 1 (S. cerevisiae) 1.28687
RAB11FIP4 RAB11 family interacting protein 4 (class II) 1.28658
MOSPD3 motile sperm domain containing 3 1.28628
ACO1 aconitase 1, soluble 1.28149
CCDC6 coiled-coil domain containing 6 1.27986
TMEM248 transmembrane protein 248 1.27981
ANAPC16 anaphase promoting complex subunit 16 1.27619
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.2747
SLC26A1 solute carrier family 26 (anion exchanger), member 1 1.27451
ACP2 acid phosphatase 2, lysosomal 1.27385
PHF23 PHD finger protein 23 1.27149
RABEPK Rab9 effector protein with kelch motifs 1.27041
BUB3 BUB3 mitotic checkpoint protein 1.2682
LAMB2 laminin, beta 2 (laminin S) 1.2672
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.26209
EIF3H eukaryotic translation initiation factor 3, subunit H 1.25929
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.25884
CTPS2 CTP synthase 2 1.25875
MRPL43 mitochondrial ribosomal protein L43 1.25868
CDK20 cyclin-dependent kinase 20 1.25699
CRAT carnitine O-acetyltransferase 1.25433
RABAC1 Rab acceptor 1 (prenylated) 1.25308
TSC22D1 TSC22 domain family, member 1 1.24945
TBC1D10A TBC1 domain family, member 10A 1.24862
DCAF11 DDB1 and CUL4 associated factor 11 1.24836
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.24821
WRB tryptophan rich basic protein 1.24561
TMEM127 transmembrane protein 127 1.24296
PARL presenilin associated, rhomboid-like 1.2429
GSTM5 glutathione S-transferase mu 5 1.24278
GUSB glucuronidase, beta 1.24124
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 1.24037
EIF4B eukaryotic translation initiation factor 4B 1.23994
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.23625
PITPNA phosphatidylinositol transfer protein, alpha 1.23333
DGKD diacylglycerol kinase, delta 130kDa 1.23236
ATF4 activating transcription factor 4 1.2318

decreased expression

Symbol Name Standardized Value
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -4.59926
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -4.01211
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.90961
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -3.72154
NID2 nidogen 2 (osteonidogen) -3.67294
HUS1 HUS1 checkpoint homolog (S. pombe) -3.60762
FAM49B family with sequence similarity 49, member B -3.50585
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -3.39151
ENTHD2 ENTH domain containing 2 -3.33221
UBE2K ubiquitin-conjugating enzyme E2K -3.25633
MAD2L1BP MAD2L1 binding protein -3.21497
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -3.10466
CLMP CXADR-like membrane protein -3.02392
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.01204
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.8883
TMED7 transmembrane emp24 protein transport domain containing 7 -2.87462
STK17B serine/threonine kinase 17b -2.78241
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.77098
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.73876
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.71464
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -2.64956
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -2.6368
VWA8 von Willebrand factor A domain containing 8 -2.60766
ARL5A ADP-ribosylation factor-like 5A -2.58254
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -2.57738
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.57512
MARCKSL1 MARCKS-like 1 -2.56709
FAM111A family with sequence similarity 111, member A -2.56264
PCGF3 polycomb group ring finger 3 -2.40098
ART3 ADP-ribosyltransferase 3 -2.38142
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.36279
TBK1 TANK-binding kinase 1 -2.29715
NUP93 nucleoporin 93kDa -2.28934
DENND5A DENN/MADD domain containing 5A -2.27632
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.27196
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -2.2411
WDR89 WD repeat domain 89 -2.23588
SLC35E1 solute carrier family 35, member E1 -2.23134
CORO1C coronin, actin binding protein, 1C -2.22875
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.21502
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -2.20115
LAPTM4A lysosomal protein transmembrane 4 alpha -2.19221
IGFBP7 insulin-like growth factor binding protein 7 -2.18861
SFN stratifin -2.16107
INPP5J inositol polyphosphate-5-phosphatase J -2.15947
MRPS25 mitochondrial ribosomal protein S25 -2.14718
SELT selenoprotein T -2.13881
KANK1 KN motif and ankyrin repeat domains 1 -2.13092
M6PR mannose-6-phosphate receptor (cation dependent) -2.11005
CDADC1 cytidine and dCMP deaminase domain containing 1 -2.08945
MYBBP1A MYB binding protein (P160) 1a -2.08173
ZBTB39 zinc finger and BTB domain containing 39 -2.07416
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.06576
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.05778
CLDN2 claudin 2 -2.05067
DET1 de-etiolated homolog 1 (Arabidopsis) -2.02968
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -2.02297
ORC5 origin recognition complex, subunit 5 -2.01614
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.01016
MYH11 myosin, heavy chain 11, smooth muscle -2.00363
ACSL5 acyl-CoA synthetase long-chain family member 5 -2.003
HHEX hematopoietically expressed homeobox -2.00022
AKAP10 A kinase (PRKA) anchor protein 10 -1.99075
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -1.9827
IL15 interleukin 15 -1.98076
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -1.96748
PTCD2 pentatricopeptide repeat domain 2 -1.9671
PTRH2 peptidyl-tRNA hydrolase 2 -1.95282
ARHGAP17 Rho GTPase activating protein 17 -1.95149
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.95109
H2AFY H2A histone family, member Y -1.93314
ANXA1 annexin A1 -1.92297
CPN1 carboxypeptidase N, polypeptide 1 -1.91762
PRKCQ protein kinase C, theta -1.91584
AGK acylglycerol kinase -1.90885
QDPR quinoid dihydropteridine reductase -1.90707
SRSF6 serine/arginine-rich splicing factor 6 -1.8895
SP110 SP110 nuclear body protein -1.88942
CXCL10 chemokine (C-X-C motif) ligand 10 -1.88794
TIPIN TIMELESS interacting protein -1.86681
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -1.85353
BIRC3 baculoviral IAP repeat containing 3 -1.84971
LMAN2L lectin, mannose-binding 2-like -1.84729
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -1.84498
SQRDL sulfide quinone reductase-like (yeast) -1.83747
TRMT6 tRNA methyltransferase 6 -1.82842
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.82687
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -1.81956
INTS5 integrator complex subunit 5 -1.8162
OCEL1 occludin/ELL domain containing 1 -1.8154
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.80816
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -1.80468
TMEM98 transmembrane protein 98 -1.79761
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 -1.78995
DUSP16 dual specificity phosphatase 16 -1.78743
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.78679
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -1.76773
MFSD6 major facilitator superfamily domain containing 6 -1.76589
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -1.76283
GLIS2 GLIS family zinc finger 2 -1.75941
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -1.75884
MANF mesencephalic astrocyte-derived neurotrophic factor -1.75766
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -1.75612
PGAM1 phosphoglycerate mutase 1 (brain) -1.74898
SLC35B1 solute carrier family 35, member B1 -1.73971
FXYD6 FXYD domain containing ion transport regulator 6 -1.73492
CD63 CD63 molecule -1.73285
ASB6 ankyrin repeat and SOCS box containing 6 -1.73012
RGS5 regulator of G-protein signaling 5 -1.7289
PGGT1B protein geranylgeranyltransferase type I, beta subunit -1.707
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -1.70343
MOCS2 molybdenum cofactor synthesis 2 -1.69996
SNX6 sorting nexin 6 -1.68309
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha -1.68267
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -1.67985
DYNLL1 dynein, light chain, LC8-type 1 -1.67218
C1QTNF3 C1q and tumor necrosis factor related protein 3 -1.66365
NARF nuclear prelamin A recognition factor -1.66052
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 -1.65973
DCAKD dephospho-CoA kinase domain containing -1.65394
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 -1.65234
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -1.6521
SRSF1 serine/arginine-rich splicing factor 1 -1.65007
XPO5 exportin 5 -1.64874
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -1.64405
EXOC5 exocyst complex component 5 -1.63631
TTYH3 tweety family member 3 -1.6304
ZNF580 zinc finger protein 580 -1.62864
SIAE sialic acid acetylesterase -1.62314
MAPK12 mitogen-activated protein kinase 12 -1.62149
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -1.61788
CLIP2 CAP-GLY domain containing linker protein 2 -1.61284
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -1.61012
TGFBR1 transforming growth factor, beta receptor 1 -1.6076
RNF4 ring finger protein 4 -1.60679
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 -1.60469
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -1.60272
NXF1 nuclear RNA export factor 1 -1.59849
AQR aquarius intron-binding spliceosomal factor -1.59703
PGS1 phosphatidylglycerophosphate synthase 1 -1.59691
KLHL22 kelch-like family member 22 -1.59636
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.59539
ADGRL2 adhesion G protein-coupled receptor L2 -1.59456
SDF2L1 stromal cell-derived factor 2-like 1 -1.59161
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -1.5868
GMFB glia maturation factor, beta -1.58447
NTF3 neurotrophin 3 -1.58273
GJB4 gap junction protein, beta 4, 30.3kDa -1.57821
SRSF3 serine/arginine-rich splicing factor 3 -1.57694
RNF213 ring finger protein 213 -1.5733
ARFIP1 ADP-ribosylation factor interacting protein 1 -1.573
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.57223
TM4SF1 transmembrane 4 L six family member 1 -1.56928
HABP4 hyaluronan binding protein 4 -1.56777
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -1.56705
SHARPIN SHANK-associated RH domain interactor -1.56201
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -1.56119
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.56024
GLTP glycolipid transfer protein -1.55909
YLPM1 YLP motif containing 1 -1.55155
GMPR2 guanosine monophosphate reductase 2 -1.55131
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -1.54739
RILPL1 Rab interacting lysosomal protein-like 1 -1.54663
METAP1 methionyl aminopeptidase 1 -1.54607
TRIP10 thyroid hormone receptor interactor 10 -1.54403
ANXA6 annexin A6 -1.53459
SLFN12L schlafen family member 12-like -1.52987
CCND1 cyclin D1 -1.52886
LMO4 LIM domain only 4 -1.52241
VTA1 vesicle (multivesicular body) trafficking 1 -1.5221
NUP205 nucleoporin 205kDa -1.52096
PLLP plasmolipin -1.5143
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -1.50784
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.50783
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -1.50671
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.50398
XAB2 XPA binding protein 2 -1.49931
PTRHD1 peptidyl-tRNA hydrolase domain containing 1 -1.49922
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -1.49868
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.49077
ACMSD aminocarboxymuconate semialdehyde decarboxylase -1.48707
USP18 ubiquitin specific peptidase 18 -1.48154
FAM114A1 family with sequence similarity 114, member A1 -1.47892
RNF26 ring finger protein 26 -1.47863
RSAD2 radical S-adenosyl methionine domain containing 2 -1.47716
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.47622
TYSND1 trypsin domain containing 1 -1.47593
COL4A4 collagen, type IV, alpha 4 -1.47333
HSPA2 heat shock 70kDa protein 2 -1.46995
PTER phosphotriesterase related -1.46602
GLYCTK glycerate kinase -1.46399
CALR calreticulin -1.45812
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -1.45793
KARS lysyl-tRNA synthetase -1.45777
SLC44A1 solute carrier family 44 (choline transporter), member 1 -1.45553
MFSD5 major facilitator superfamily domain containing 5 -1.44632
BMP3 bone morphogenetic protein 3 -1.44363
HN1 hematological and neurological expressed 1 -1.44087
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.44066
CD46 CD46 molecule, complement regulatory protein -1.43847
CLIC4 chloride intracellular channel 4 -1.43688
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.43598
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.43578
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -1.43231
MTPN myotrophin -1.42419
ARFRP1 ADP-ribosylation factor related protein 1 -1.41799
ZNF180 zinc finger protein 180 -1.41495
TMBIM4 transmembrane BAX inhibitor motif containing 4 -1.41234
SYNJ2BP synaptojanin 2 binding protein -1.40573
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.40325
CBWD1 COBW domain containing 1 -1.40293
LHFP lipoma HMGIC fusion partner -1.39804
AFAP1L2 actin filament associated protein 1-like 2 -1.39711
SEPT11 septin 11 -1.39692
SEPT2 septin 2 -1.39517
RAB2A RAB2A, member RAS oncogene family -1.39226
RFC4 replication factor C (activator 1) 4, 37kDa -1.39002
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -1.38807
BIRC5 baculoviral IAP repeat containing 5 -1.38718
CDCA7 cell division cycle associated 7 -1.38698
GALT galactose-1-phosphate uridylyltransferase -1.38697
NEXN nexilin (F actin binding protein) -1.3819
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -1.38144
SAYSD1 SAYSVFN motif domain containing 1 -1.37995
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.37904
CD83 CD83 molecule -1.37885
KIF3B kinesin family member 3B -1.37847
COPS7A COP9 signalosome subunit 7A -1.37703
WBP1 WW domain binding protein 1 -1.37629
WDR5 WD repeat domain 5 -1.37599
CERCAM cerebral endothelial cell adhesion molecule -1.37423
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.37031
TOP2A topoisomerase (DNA) II alpha 170kDa -1.37001
SIKE1 suppressor of IKBKE 1 -1.36862
SH2B3 SH2B adaptor protein 3 -1.36393
NUP155 nucleoporin 155kDa -1.36131
LDHA lactate dehydrogenase A -1.3592
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 -1.35672
IFT122 intraflagellar transport 122 -1.35646
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -1.35555
RNF167 ring finger protein 167 -1.3553
MPC1 mitochondrial pyruvate carrier 1 -1.35434
APLN apelin -1.354
CYR61 cysteine-rich, angiogenic inducer, 61 -1.35284
PIAS2 protein inhibitor of activated STAT, 2 -1.34985
CCNB2 cyclin B2 -1.34824
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) -1.34645
RAB6A RAB6A, member RAS oncogene family -1.34582
MSN moesin -1.34386
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -1.34234
CCDC8 coiled-coil domain containing 8 -1.34192
RAB11B RAB11B, member RAS oncogene family -1.33845
AMPD2 adenosine monophosphate deaminase 2 -1.33681
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.33433
TMEM80 transmembrane protein 80 -1.33156
FKBP1A FK506 binding protein 1A, 12kDa -1.33119
SEP15 15 kDa selenoprotein -1.32824
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.32787
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -1.32643
USP8 ubiquitin specific peptidase 8 -1.32458
HIRIP3 HIRA interacting protein 3 -1.3227
TBC1D10B TBC1 domain family, member 10B -1.32197
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 -1.31957
GOLPH3 golgi phosphoprotein 3 (coat-protein) -1.31872
OAZ1 ornithine decarboxylase antizyme 1 -1.31123
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.3094
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -1.30556
NUDCD1 NudC domain containing 1 -1.30131
WBSCR16 Williams-Beuren syndrome chromosome region 16 -1.29942
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -1.29663
ARF1 ADP-ribosylation factor 1 -1.29449
FBXO34 F-box protein 34 -1.29143
MXI1 MAX interactor 1, dimerization protein -1.28278
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -1.28064
HTT huntingtin -1.27894
IL33 interleukin 33 -1.27879
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -1.27532
IMPACT impact RWD domain protein -1.27438
PTPRF protein tyrosine phosphatase, receptor type, F -1.27369
CHMP1A charged multivesicular body protein 1A -1.27349
PARP14 poly (ADP-ribose) polymerase family, member 14 -1.27313
SCHIP1 schwannomin interacting protein 1 -1.27221
STRN3 striatin, calmodulin binding protein 3 -1.26944
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -1.26742
TFG TRK-fused gene -1.26169
CRNKL1 crooked neck pre-mRNA splicing factor 1 -1.26164
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -1.26073
EPM2AIP1 EPM2A (laforin) interacting protein 1 -1.25975
SKAP2 src kinase associated phosphoprotein 2 -1.25933
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.25725
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -1.25722
HNF1B HNF1 homeobox B -1.2559
BOK BCL2-related ovarian killer -1.25444
TTC23 tetratricopeptide repeat domain 23 -1.25305
HSPA4 heat shock 70kDa protein 4 -1.24604
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.24121
ERCC2 excision repair cross-complementation group 2 -1.23403
ITGAD integrin, alpha D -1.23333
HSPA9 heat shock 70kDa protein 9 (mortalin) -1.23224
PDIA6 protein disulfide isomerase family A, member 6 -1.23169
Funding