Hypothermia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Reduced body temperature due to failed thermoregulation. (Human Phenotype Ontology, HP_0002045)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007035
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Genes

1086 genes/proteins associated with the disease Hypothermia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CNR1 cannabinoid receptor 1 (brain) 2.88009
SOD1 superoxide dismutase 1, soluble 2.88009
TNF tumor necrosis factor 2.88009
IL12B interleukin 12B 2.88009
IL12A interleukin 12A 2.88009
LHB luteinizing hormone beta polypeptide 2.88009
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.88009
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.88009
TRH thyrotropin-releasing hormone 2.88009
TSHB thyroid stimulating hormone, beta 2.88009
GCG glucagon 2.88009
FOS FBJ murine osteosarcoma viral oncogene homolog 2.53651
DRD2 dopamine receptor D2 2.50751
CAT catalase 2.46061
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.46035
MAPK1 mitogen-activated protein kinase 1 2.45353
MAPK3 mitogen-activated protein kinase 3 2.44828
NPY neuropeptide Y 2.43061
BDNF brain-derived neurotrophic factor 2.42518
BAX BCL2-associated X protein 2.41559
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.41503
EGR1 early growth response 1 2.41206
JUN jun proto-oncogene 2.4065
JUNB jun B proto-oncogene 2.38427
TH tyrosine hydroxylase 2.38206
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.37241
PRL prolactin 2.36894
CREB1 cAMP responsive element binding protein 1 2.34981
TAC1 tachykinin, precursor 1 2.33823
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.32861
NOS2 nitric oxide synthase 2, inducible 2.32202
IL1B interleukin 1, beta 2.30854
CRH corticotropin releasing hormone 2.30707
BCL2 B-cell CLL/lymphoma 2 2.30483
ACHE acetylcholinesterase (Yt blood group) 2.3047
IL6 interleukin 6 2.30207
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.2958
DRD1 dopamine receptor D1 2.29498
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.26478
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.25975
SOD2 superoxide dismutase 2, mitochondrial 2.24066
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.23241
GSK3B glycogen synthase kinase 3 beta 2.23165
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.22357
GFAP glial fibrillary acidic protein 2.22207
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.21857
TP53 tumor protein p53 2.21815
IFNG interferon, gamma 2.21438
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.21023
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.20977
POMC proopiomelanocortin 2.20805
FAS Fas cell surface death receptor 2.20212
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.20157
ARC activity-regulated cytoskeleton-associated protein 2.19776
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.19389
BCL2L1 BCL2-like 1 2.18561
PENK proenkephalin 2.17987
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.17009
HMOX1 heme oxygenase 1 2.16006
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.15976
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.15771
MAPK8 mitogen-activated protein kinase 8 2.14742
NOS1 nitric oxide synthase 1 (neuronal) 2.13535
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.11612
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.11553
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.11104
IL10 interleukin 10 2.10575
DDIT3 DNA-damage-inducible transcript 3 2.10297
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.09997
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.09499
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.09119
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.08918
IL2 interleukin 2 2.08308
DUSP1 dual specificity phosphatase 1 2.06997
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.05918
PRKCD protein kinase C, delta 2.05193
CXCL8 chemokine (C-X-C motif) ligand 8 2.04618
MAOA monoamine oxidase A 2.04593
IL1A interleukin 1, alpha 2.04371
ADORA2A adenosine A2a receptor 2.04267
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.03912
PARP1 poly (ADP-ribose) polymerase 1 2.03573
MAOB monoamine oxidase B 2.03198
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.02782
GSTP1 glutathione S-transferase pi 1 2.02417
PDYN prodynorphin 2.01159
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.0055
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.97771
PRKCB protein kinase C, beta 1.97332
VEGFA vascular endothelial growth factor A 1.96876
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.95676
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.9542
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.95209
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.9498
GSR glutathione reductase 1.93521
OPRM1 opioid receptor, mu 1 1.93353
ALB albumin 1.93231
LEP leptin 1.9269
NUPR1 nuclear protein, transcriptional regulator, 1 1.92156
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.91862
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.9183
GAL galanin/GMAP prepropeptide 1.91384
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.91384
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.91368
RELN reelin 1.8965
CDK5 cyclin-dependent kinase 5 1.89232
MMP9 matrix metallopeptidase 9 1.88655
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.87908
IGF1 insulin-like growth factor 1 (somatomedin C) 1.87492
GRM1 glutamate receptor, metabotropic 1 1.8641
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.86201
CES2 carboxylesterase 2 1.85957
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.8538
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.85186
CALR calreticulin 1.84994
RGS2 regulator of G-protein signaling 2 1.84517
CALCA calcitonin-related polypeptide alpha 1.84287
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.84269
HSPA1A heat shock 70kDa protein 1A 1.83771
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.83592
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.83485
PRKCZ protein kinase C, zeta 1.83485
NGF nerve growth factor (beta polypeptide) 1.83272
EDN1 endothelin 1 1.82761
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.82743
CCK cholecystokinin 1.82516
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.82481
GRIK2 glutamate receptor, ionotropic, kainate 2 1.82359
CHRM1 cholinergic receptor, muscarinic 1 1.8222
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.82202
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.82185
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.81976
HOMER1 homer scaffolding protein 1 1.81702
CYCS cytochrome c, somatic 1.80491
BCHE butyrylcholinesterase 1.80172
GAP43 growth associated protein 43 1.79618
ADORA1 adenosine A1 receptor 1.79579
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.79369
MAPK14 mitogen-activated protein kinase 14 1.79197
ODC1 ornithine decarboxylase 1 1.78568
JUND jun D proto-oncogene 1.78568
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.78511
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.78492
GADD45A growth arrest and DNA-damage-inducible, alpha 1.78359
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.78149
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.77994
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.77413
DRD4 dopamine receptor D4 1.77296
LPL lipoprotein lipase 1.77179
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.77179
INS insulin 1.7714
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.77043
CCL5 chemokine (C-C motif) ligand 5 1.76481
MAP2K1 mitogen-activated protein kinase kinase 1 1.76405
CCND1 cyclin D1 1.7621
DRD3 dopamine receptor D3 1.76032
MPO myeloperoxidase 1.76013
BBC3 BCL2 binding component 3 1.75875
HSPA8 heat shock 70kDa protein 8 1.75875
FABP1 fatty acid binding protein 1, liver 1.74701
MAP2K2 mitogen-activated protein kinase kinase 2 1.7446
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.7422
FGF2 fibroblast growth factor 2 (basic) 1.73516
CCND3 cyclin D3 1.73332
GDNF glial cell derived neurotrophic factor 1.73211
ESR1 estrogen receptor 1 1.73069
EGFR epidermal growth factor receptor 1.72884
CCL2 chemokine (C-C motif) ligand 2 1.728
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.72675
SREBF1 sterol regulatory element binding transcription factor 1 1.72675
REN renin 1.72529
GPX3 glutathione peroxidase 3 1.72426
PER2 period circadian clock 2 1.72199
AVP arginine vasopressin 1.71871
S100B S100 calcium binding protein B 1.71871
EGR2 early growth response 2 1.71606
STAR steroidogenic acute regulatory protein 1.71379
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.71358
COMT catechol-O-methyltransferase 1.71029
PRKCA protein kinase C, alpha 1.70119
ICAM1 intercellular adhesion molecule 1 1.69972
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.69951
SYP synaptophysin 1.69659
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.69659
TGFB1 transforming growth factor, beta 1 1.69638
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.69513
OPRK1 opioid receptor, kappa 1 1.6906
PRKCE protein kinase C, epsilon 1.68825
NEFH neurofilament, heavy polypeptide 1.68464
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.6819
CHAT choline O-acetyltransferase 1.68148
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.67847
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.67547
UBC ubiquitin C 1.67398
APP amyloid beta (A4) precursor protein 1.669
DUSP6 dual specificity phosphatase 6 1.66878
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.66749
C10ORF10 chromosome 10 open reading frame 10 1.66446
MAP2 microtubule-associated protein 2 1.66317
IL4 interleukin 4 1.66274
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.66102
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.65864
GRM5 glutamate receptor, metabotropic 5 1.65533
ATF3 activating transcription factor 3 1.65467
ADCY5 adenylate cyclase 5 1.65091
OXT oxytocin/neurophysin I prepropeptide 1.65
PLCG1 phospholipase C, gamma 1 1.64933
TAGLN transgelin 1.6473
FOSL2 FOS-like antigen 2 1.64573
NQO1 NAD(P)H dehydrogenase, quinone 1 1.64438
PPARG peroxisome proliferator-activated receptor gamma 1.64348
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.64235
BAK1 BCL2-antagonist/killer 1 1.63877
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.63765
INHBE inhibin, beta E 1.63563
NCAM1 neural cell adhesion molecule 1 1.63339
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.63294
GRIK5 glutamate receptor, ionotropic, kainate 5 1.6287
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.62669
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.62246
POR P450 (cytochrome) oxidoreductase 1.62036
RET ret proto-oncogene 1.6192
IGFBP1 insulin-like growth factor binding protein 1 1.6146
DLG4 discs, large homolog 4 (Drosophila) 1.61342
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.61295
ACTB actin, beta 1.60804
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.60804
BID BH3 interacting domain death agonist 1.60758
GSTM1 glutathione S-transferase mu 1 1.60734
CHRM3 cholinergic receptor, muscarinic 3 1.60641
UNG uracil-DNA glycosylase 1.60641
CPT1A carnitine palmitoyltransferase 1A (liver) 1.60594
MAPK9 mitogen-activated protein kinase 9 1.60454
CCL3 chemokine (C-C motif) ligand 3 1.60151
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.59849
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.59802
GSTA2 glutathione S-transferase alpha 2 1.59685
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.59567
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.59381
CREM cAMP responsive element modulator 1.59101
FOSL1 FOS-like antigen 1 1.58936
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.58912
GJA1 gap junction protein, alpha 1, 43kDa 1.58748
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.58561
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.58537
EIF5 eukaryotic translation initiation factor 5 1.58514
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.58255
FN1 fibronectin 1 1.579
HRAS Harvey rat sarcoma viral oncogene homolog 1.57712
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.57018
NTS neurotensin 1.56681
NTSR1 neurotensin receptor 1 (high affinity) 1.56509
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.56312
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.56141
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.56141
MMP7 matrix metallopeptidase 7 1.55946
ADCY8 adenylate cyclase 8 (brain) 1.55921
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.55747
ADRB2 adrenoceptor beta 2, surface 1.5555
GPX1 glutathione peroxidase 1 1.55255
ADRA2A adrenoceptor alpha 2A 1.55231
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.55206
COL1A1 collagen, type I, alpha 1 1.55206
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.55206
SIRT1 sirtuin 1 1.55157
LDLR low density lipoprotein receptor 1.54596
HSPB1 heat shock 27kDa protein 1 1.54548
PPARA peroxisome proliferator-activated receptor alpha 1.54306
CXCL10 chemokine (C-X-C motif) ligand 10 1.53917
TJP1 tight junction protein 1 1.53675
CES1 carboxylesterase 1 1.53627
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.53456
CCNE1 cyclin E1 1.53283
ERN1 endoplasmic reticulum to nucleus signaling 1 1.53209
FSHB follicle stimulating hormone, beta polypeptide 1.5311
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.53036
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.52914
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.52865
CARTPT CART prepropeptide 1.5284
CTSB cathepsin B 1.52743
KRAS Kirsten rat sarcoma viral oncogene homolog 1.52743
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.52591
PCNA proliferating cell nuclear antigen 1.52413
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.52338
ATF4 activating transcription factor 4 1.52313
GCLC glutamate-cysteine ligase, catalytic subunit 1.52061
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.51936
ABAT 4-aminobutyrate aminotransferase 1.51759
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.51557
PLAT plasminogen activator, tissue 1.51305
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.51305
BAD BCL2-associated agonist of cell death 1.5113
IGF1R insulin-like growth factor 1 receptor 1.5103
FNDC4 fibronectin type III domain containing 4 1.50852
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.50801
TLR4 toll-like receptor 4 1.50776
HPN hepsin 1.50599
CTSD cathepsin D 1.50423
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.50423
PDE10A phosphodiesterase 10A 1.50095
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.50095
NPPA natriuretic peptide A 1.50069
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.50069
ADRB1 adrenoceptor beta 1 1.49787
POU5F1 POU class 5 homeobox 1 1.49736
OPRD1 opioid receptor, delta 1 1.49736
HDAC1 histone deacetylase 1 1.49686
CYBB cytochrome b-245, beta polypeptide 1.49558
TFRC transferrin receptor 1.49381
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.49356
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.48967
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.4871
ADCY9 adenylate cyclase 9 1.48608
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.48531
CHRM2 cholinergic receptor, muscarinic 2 1.48479
GH1 growth hormone 1 1.48325
NFE2L2 nuclear factor, erythroid 2-like 2 1.48299
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.48196
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.4817
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.4817
HRH1 histamine receptor H1 1.4817
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.4817
CFLAR CASP8 and FADD-like apoptosis regulator 1.48093
PVALB parvalbumin 1.47991
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.47991
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.47991
MSMO1 methylsterol monooxygenase 1 1.47889
IRS1 insulin receptor substrate 1 1.47864
RGS4 regulator of G-protein signaling 4 1.47813
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.47504
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.47452
LITAF lipopolysaccharide-induced TNF factor 1.47452
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.47296
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.4727
EFNA1 ephrin-A1 1.47089
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.46701
RB1 retinoblastoma 1 1.46674
FASN fatty acid synthase 1.46542
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.46515
EDNRB endothelin receptor type B 1.46462
MBP myelin basic protein 1.46436
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.46356
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.46251
FGFR1 fibroblast growth factor receptor 1 1.46172
MAP1B microtubule-associated protein 1B 1.46041
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.45857
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.45857
GRM7 glutamate receptor, metabotropic 7 1.45697
ARRB2 arrestin, beta 2 1.45564
GSTM2 glutathione S-transferase mu 2 (muscle) 1.45299
ATF6 activating transcription factor 6 1.44927
CRYAB crystallin, alpha B 1.44872
SGK1 serum/glucocorticoid regulated kinase 1 1.44872
SHH sonic hedgehog 1.44626
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.44544
IL1R1 interleukin 1 receptor, type I 1.4449
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.44219
EZR ezrin 1.44219
PRDX2 peroxiredoxin 2 1.44193
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1.44166
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.44166
E2F1 E2F transcription factor 1 1.43974
TIMP1 TIMP metallopeptidase inhibitor 1 1.43919
TRIB3 tribbles pseudokinase 3 1.43727
S100A9 S100 calcium binding protein A9 1.43646
BTG2 BTG family, member 2 1.43293
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.43266
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.43266
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.43266
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.43184
RPS6 ribosomal protein S6 1.42859
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.42804
GCLM glutamate-cysteine ligase, modifier subunit 1.42723
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.42642
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.42642
H2AFX H2A histone family, member X 1.42508
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.42508
MYD88 myeloid differentiation primary response 88 1.42508
HSPA4 heat shock 70kDa protein 4 1.42183
PRKD3 protein kinase D3 1.42047
EFNB3 ephrin-B3 1.41938
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41802
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.41559
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.41313
SREBF2 sterol regulatory element binding transcription factor 2 1.41091
EIF5A eukaryotic translation initiation factor 5A 1.41091
SQSTM1 sequestosome 1 1.4098
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.40897
GPX2 glutathione peroxidase 2 1.40541
TMEM125 transmembrane protein 125 1.40486
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.40486
MAP2K5 mitogen-activated protein kinase kinase 5 1.40316
OPRL1 opiate receptor-like 1 1.40316
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.40232
CYBA cytochrome b-245, alpha polypeptide 1.40036
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.39869
EGR3 early growth response 3 1.39451
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.39451
HPCAL4 hippocalcin like 4 1.39394
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.39394
HNF4A hepatocyte nuclear factor 4, alpha 1.3931
CCNG1 cyclin G1 1.39058
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.39002
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.38807
FOXO1 forkhead box O1 1.38724
MEF2C myocyte enhancer factor 2C 1.38669
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 1.38612
ATF2 activating transcription factor 2 1.38412
CDC6 cell division cycle 6 1.38412
CCNA1 cyclin A1 1.3827
FAAH fatty acid amide hydrolase 1.3827
INHA inhibin, alpha 1.38128
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.37874
PER1 period circadian clock 1 1.37874
CDK4 cyclin-dependent kinase 4 1.37874
IGF2 insulin-like growth factor 2 1.37846
SRXN1 sulfiredoxin 1 1.37846
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.37817
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.37532
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.37332
CTSK cathepsin K 1.37103
ACP5 acid phosphatase 5, tartrate resistant 1.37103
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.37075
DPYSL2 dihydropyrimidinase-like 2 1.37075
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.36933
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.36905
INSIG1 insulin induced gene 1 1.36677
EFNA2 ephrin-A2 1.36677
HMBS hydroxymethylbilane synthase 1.36562
CHRM4 cholinergic receptor, muscarinic 4 1.36562
GRM2 glutamate receptor, metabotropic 2 1.36332
SCG2 secretogranin II 1.36332
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.36047
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.36019
SDC4 syndecan 4 1.35991
ELK1 ELK1, member of ETS oncogene family 1.35991
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.35991
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 1.35589
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.35502
NCF1 neutrophil cytosolic factor 1 1.35299
CASP12 caspase 12 (gene/pseudogene) 1.35213
GNAS GNAS complex locus 1.35213
PGD phosphogluconate dehydrogenase 1.35213
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1.34897
MMP13 matrix metallopeptidase 13 1.3484
CCNA2 cyclin A2 1.34811
BIRC5 baculoviral IAP repeat containing 5 1.34664
ENO1 enolase 1, (alpha) 1.34401
CRHR1 corticotropin releasing hormone receptor 1 1.34111
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.3388
ADRA1A adrenoceptor alpha 1A 1.3382
TXNRD1 thioredoxin reductase 1 1.33731
CCKBR cholecystokinin B receptor 1.33612
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.33612
ACSL5 acyl-CoA synthetase long-chain family member 5 1.33612
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.33553
MAPT microtubule-associated protein tau 1.33523
SP1 Sp1 transcription factor 1.33523
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.33523
LEPR leptin receptor 1.33523
PTEN phosphatase and tensin homolog 1.33228
IL5 interleukin 5 1.33228
G6PD glucose-6-phosphate dehydrogenase 1.33052
ATM ATM serine/threonine kinase 1.32876
IL17A interleukin 17A 1.32786
GATA3 GATA binding protein 3 1.32786
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.32696
SMAD1 SMAD family member 1 1.32696
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.32696
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.32458
CLDN1 claudin 1 1.32458
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.32221
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.32192
TIMP2 TIMP metallopeptidase inhibitor 2 1.31807
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.31807
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.31776
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.31686
FASLG Fas ligand (TNF superfamily, member 6) 1.31656
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 1.31566
NCEH1 neutral cholesterol ester hydrolase 1 1.31566
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.31566
PDE4A phosphodiesterase 4A, cAMP-specific 1.31566
FGF1 fibroblast growth factor 1 (acidic) 1.31446
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.31446
MAP2K6 mitogen-activated protein kinase kinase 6 1.31446
LIN7C lin-7 homolog C (C. elegans) 1.31327
CD40 CD40 molecule, TNF receptor superfamily member 5 1.31178
JAK1 Janus kinase 1 1.31119
SYN2 synapsin II 1.30941
GMFB glia maturation factor, beta 1.30941
CHGA chromogranin A 1.30941
PRKCI protein kinase C, iota 1.30941
GLUL glutamate-ammonia ligase 1.30911
VCAM1 vascular cell adhesion molecule 1 1.30758
STMN1 stathmin 1 1.30666
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.3039
SYT11 synaptotagmin XI 1.3036
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.30299
APAF1 apoptotic peptidase activating factor 1 1.30147
ADRA1B adrenoceptor alpha 1B 1.30117
MGLL monoglyceride lipase 1.30117
NUCLEOLIN nucleolin multifunctional protein 1.30026
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.30026
PTK2 protein tyrosine kinase 2 1.29905
PHB prohibitin 1.29812
VLDLR very low density lipoprotein receptor 1.29812
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.29812
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.29688
TXN2 thioredoxin 2 1.29595
PARK7 parkinson protein 7 1.29595
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.29471
SYT4 synaptotagmin IV 1.2944
DVL2 dishevelled segment polarity protein 2 1.2941
NTNG1 netrin G1 1.2941
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.2941
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.29379
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.29164
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.29103
LMO7 LIM domain 7 1.29103
MMP2 matrix metallopeptidase 2 1.2898
ACACA acetyl-CoA carboxylase alpha 1.28889
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.28765
TLR2 toll-like receptor 2 1.28641
HPCA hippocalcin 1.28518
CLSTN1 calsyntenin 1 1.28518
AK5 adenylate kinase 5 1.28518
HPCAL1 hippocalcin-like 1 1.28487
NFE2L1 nuclear factor, erythroid 2-like 1 1.28487
ADIPOR2 adiponectin receptor 2 1.28333
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.28333
AR androgen receptor 1.28241
PDE4B phosphodiesterase 4B, cAMP-specific 1.2821
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.27936
PYGL phosphorylase, glycogen, liver 1.27936
KLF4 Kruppel-like factor 4 (gut) 1.27905
IGFBP3 insulin-like growth factor binding protein 3 1.2772
CYR61 cysteine-rich, angiogenic inducer, 61 1.27689
PLCD4 phospholipase C, delta 4 1.27626
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.27626
SEPP1 selenoprotein P, plasma, 1 1.27626
IL2RA interleukin 2 receptor, alpha 1.27626
DUT deoxyuridine triphosphatase 1.27533
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.27378
HDAC5 histone deacetylase 5 1.27347
ASL argininosuccinate lyase 1.27347
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.27347
SYK spleen tyrosine kinase 1.27347
ALDOA aldolase A, fructose-bisphosphate 1.27316
CLIP3 CAP-GLY domain containing linker protein 3 1.27224
AQP4 aquaporin 4 1.27132
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.26978
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.26794
DUSP8 dual specificity phosphatase 8 1.26794
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.26452
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.26359
NES nestin 1.26359
GSK3A glycogen synthase kinase 3 alpha 1.26267
SOX18 SRY (sex determining region Y)-box 18 1.26267
SRSF5 serine/arginine-rich splicing factor 5 1.26267
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.26267
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.26113
CHGB chromogranin B 1.2599
NRXN3 neurexin 3 1.2596
LBP lipopolysaccharide binding protein 1.2596
ACIN1 apoptotic chromatin condensation inducer 1 1.2596
SH3GL1 SH3-domain GRB2-like 1 1.25807
GSTT1 glutathione S-transferase theta 1 1.25807
EEF2 eukaryotic translation elongation factor 2 1.25557
GPX4 glutathione peroxidase 4 1.25557
SOCS3 suppressor of cytokine signaling 3 1.25369
INSR insulin receptor 1.25276
CRP C-reactive protein, pentraxin-related 1.25245
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.25183
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.25183
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.24997
INHBA inhibin, beta A 1.24997
SST somatostatin 1.24843
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.24687
SYT9 synaptotagmin IX 1.24496
TKT transketolase 1.24465
TCF4 transcription factor 4 1.24465
CFL1 cofilin 1 (non-muscle) 1.24465
HDC histidine decarboxylase 1.24465
OPALIN oligodendrocytic myelin paranodal and inner loop protein 1.24433
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 1.24401
CTGF connective tissue growth factor 1.24338
F3 coagulation factor III (thromboplastin, tissue factor) 1.24244
TTR transthyretin 1.24244
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.24181
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.24181
PDPK1 3-phosphoinositide dependent protein kinase 1 1.24181
PDIA3 protein disulfide isomerase family A, member 3 1.2415
PYCARD PYD and CARD domain containing 1.24087
XBP1 X-box binding protein 1 1.24024
CCND2 cyclin D2 1.24024
CTH cystathionine gamma-lyase 1.23868
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.23743
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.2368
RGS8 regulator of G-protein signaling 8 1.23648
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 1.23648
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.23648
GIPC1 GIPC PDZ domain containing family, member 1 1.23648
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.23584
APOA1 apolipoprotein A-I 1.23456
BCL6 B-cell CLL/lymphoma 6 1.23392
HYDIN HYDIN, axonemal central pair apparatus protein 1.23233
SOWAHA sosondowah ankyrin repeat domain family member A 1.23201
AXIN2 axin 2 1.23169
PDLIM7 PDZ and LIM domain 7 (enigma) 1.23169
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.23074
NGFR nerve growth factor receptor 1.23011
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.23011
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.23011
THRB thyroid hormone receptor, beta 1.2279
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.22696
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.22696
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.22664
NTF3 neurotrophin 3 1.22664
RXRG retinoid X receptor, gamma 1.22664
FYN FYN proto-oncogene, Src family tyrosine kinase 1.22664
TAT tyrosine aminotransferase 1.22306
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.22209
XDH xanthine dehydrogenase 1.22209
CLU clusterin 1.22209
VIM vimentin 1.22209
PLCD1 phospholipase C, delta 1 1.22177
GRM4 glutamate receptor, metabotropic 4 1.22177
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.22177
TF transferrin 1.2208
FXYD7 FXYD domain containing ion transport regulator 7 1.22016
CBLN1 cerebellin 1 precursor 1.21984
CD44 CD44 molecule (Indian blood group) 1.21855
DDIT4 DNA-damage-inducible transcript 4 1.21663
CDC25A cell division cycle 25A 1.21631
TRIM28 tripartite motif containing 28 1.21468
NPTX2 neuronal pentraxin II 1.21468
CDK6 cyclin-dependent kinase 6 1.21435
PTK2B protein tyrosine kinase 2 beta 1.21271
LDHB lactate dehydrogenase B 1.20946
SOCS2 suppressor of cytokine signaling 2 1.20946
ACVR1B activin A receptor, type IB 1.20848
NOS3 nitric oxide synthase 3 (endothelial cell) 1.20751
TBX21 T-box 21 1.20751
SIGMAR1 sigma non-opioid intracellular receptor 1 1.2059
TGFBR1 transforming growth factor, beta receptor 1 1.2059
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.20394
IRAK1 interleukin-1 receptor-associated kinase 1 1.20295
GRN granulin 1.20262
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.20196
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.2013
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 1.20064
CDC42 cell division cycle 42 1.19933
TFDP1 transcription factor Dp-1 1.19868
SRSF1 serine/arginine-rich splicing factor 1 1.19868
SHOX2 short stature homeobox 2 1.19704
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 1.19704
S100A8 S100 calcium binding protein A8 1.19639
CA2 carbonic anhydrase II 1.19639
BAG3 BCL2-associated athanogene 3 1.19607
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.19607
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.19607
CD86 CD86 molecule 1.19574
NCOA3 nuclear receptor coactivator 3 1.19412
MAP2K7 mitogen-activated protein kinase kinase 7 1.19412
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.19412
UBE2I ubiquitin-conjugating enzyme E2I 1.19412
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.19412
NRN1 neuritin 1 1.19412
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.19279
IL13 interleukin 13 1.19179
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.18948
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.18948
PTGES prostaglandin E synthase 1.18948
APEH acylaminoacyl-peptide hydrolase 1.18783
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.18783
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 1.18751
FER fer (fps/fes related) tyrosine kinase 1.18652
SSTR4 somatostatin receptor 4 1.18652
TUBB4A tubulin, beta 4A class IVa 1.18652
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.18652
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.1862
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.1862
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.1862
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.18521
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.18521
GSTA1 glutathione S-transferase alpha 1 1.18293
CHUK conserved helix-loop-helix ubiquitous kinase 1.18159
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.18126
COX7B cytochrome c oxidase subunit VIIb 1.18126
IL23A interleukin 23, alpha subunit p19 1.18093
CXCL2 chemokine (C-X-C motif) ligand 2 1.17761
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.17662
CAPN10 calpain 10 1.17629
SCN1B sodium channel, voltage gated, type I beta subunit 1.17497
COX6C cytochrome c oxidase subunit VIc 1.17497
ADRBK2 adrenergic, beta, receptor kinase 2 1.17497
HSF1 heat shock transcription factor 1 1.17366
TGFB3 transforming growth factor, beta 3 1.17366
GCK glucokinase (hexokinase 4) 1.17366
ALAS2 5'-aminolevulinate synthase 2 1.17235
TXN thioredoxin 1.17168
FZD5 frizzled class receptor 5 1.169
GSTK1 glutathione S-transferase kappa 1 1.16833
G6PC3 glucose 6 phosphatase, catalytic, 3 1.16633
REM2 RAS (RAD and GEM)-like GTP binding 2 1.16633
NXPH3 neurexophilin 3 1.16633
TEX261 testis expressed 261 1.16633
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.16467
CD80 CD80 molecule 1.16467
CKB creatine kinase, brain 1.16467
RPL6 ribosomal protein L6 1.16434
RTN4 reticulon 4 1.16434
SOCS1 suppressor of cytokine signaling 1 1.16434
ADRA2C adrenoceptor alpha 2C 1.16335
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.16302
PLA2G12A phospholipase A2, group XIIA 1.16302
GALE UDP-galactose-4-epimerase 1.16302
CD151 CD151 molecule (Raph blood group) 1.16302
NSF N-ethylmaleimide-sensitive factor 1.16302
SC5D sterol-C5-desaturase 1.16035
HBB hemoglobin, beta 1.15865
GRID2 glutamate receptor, ionotropic, delta 2 1.15831
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.15695
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.15627
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.15627
FABP7 fatty acid binding protein 7, brain 1.15593
BIK BCL2-interacting killer (apoptosis-inducing) 1.15593
GSTA3 glutathione S-transferase alpha 3 1.15526
IL1RN interleukin 1 receptor antagonist 1.15324
EFHD1 EF-hand domain family, member D1 1.15122
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.15122
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.15122
ARRB1 arrestin, beta 1 1.15122
GFRA2 GDNF family receptor alpha 2 1.15122
RHOQ ras homolog family member Q 1.15122
EFNB1 ephrin-B1 1.15122
HSPA1B heat shock 70kDa protein 1B 1.15089
ARG2 arginase 2 1.14989
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.14989
CIRBP cold inducible RNA binding protein 1.14816
HMHA1 histocompatibility (minor) HA-1 1.14747
EYA2 EYA transcriptional coactivator and phosphatase 2 1.14747
GPR88 G protein-coupled receptor 88 1.14747
PRRC2A proline-rich coiled-coil 2A 1.14747
DHCR7 7-dehydrocholesterol reductase 1.14678
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.14678
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.14644
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.1461
VGF VGF nerve growth factor inducible 1.14575
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.14575
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.14541
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.14438
CDKN2A cyclin-dependent kinase inhibitor 2A 1.14234
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 1.14098
ZEB1 zinc finger E-box binding homeobox 1 1.1403
HDAC3 histone deacetylase 3 1.13997
PRKCH protein kinase C, eta 1.13997
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 1.13862
ADCY1 adenylate cyclase 1 (brain) 1.13862
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.13862
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 1.13862
RPL26 ribosomal protein L26 1.13862
ANO3 anoctamin 3 1.13862
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.13655
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.13518
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.13518
SDS serine dehydratase 1.13449
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.13449
CXCR4 chemokine (C-X-C motif) receptor 4 1.13279
CSTB cystatin B (stefin B) 1.13279
IDI1 isopentenyl-diphosphate delta isomerase 1 1.13245
TOP2A topoisomerase (DNA) II alpha 170kDa 1.13143
PON1 paraoxonase 1 1.13143
TRHR thyrotropin-releasing hormone receptor 1.13007
GRIK3 glutamate receptor, ionotropic, kainate 3 1.13007
GRM3 glutamate receptor, metabotropic 3 1.13007
STRIP2 striatin interacting protein 2 1.13007
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.13007
STX1B syntaxin 1B 1.13007
DUSP7 dual specificity phosphatase 7 1.13007
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 1.12973
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.12973
NRG1 neuregulin 1 1.12973
TGIF2 TGFB-induced factor homeobox 2 1.12973
TK1 thymidine kinase 1, soluble 1.12703
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.12703
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.1253
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.12391
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.12391
SYNE1 spectrin repeat containing, nuclear envelope 1 1.12391
DLG1 discs, large homolog 1 (Drosophila) 1.12391
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.12391
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.12391
POU2F1 POU class 2 homeobox 1 1.12391
HTRA2 HtrA serine peptidase 2 1.12391
STAT1 signal transducer and activator of transcription 1, 91kDa 1.12288
GSTM3 glutathione S-transferase mu 3 (brain) 1.12219
CCNF cyclin F 1.12185
GRIK1 glutamate receptor, ionotropic, kainate 1 1.12185
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.12185
CTSL cathepsin L 1.12151
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 1.12151
SOX13 SRY (sex determining region Y)-box 13 1.12151
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.11877
SOD3 superoxide dismutase 3, extracellular 1.11877
BMP4 bone morphogenetic protein 4 1.11877
ACSL6 acyl-CoA synthetase long-chain family member 6 1.11877
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.11809
FOXO3 forkhead box O3 1.11639
PSEN1 presenilin 1 1.11466
MAP1A microtubule-associated protein 1A 1.1136
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.1136
DCAF8 DDB1 and CUL4 associated factor 8 1.1136
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.1136
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.1136
UBB ubiquitin B 1.1136
SQLE squalene epoxidase 1.1136
GNB5 guanine nucleotide binding protein (G protein), beta 5 1.1136
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.1136
SLIT2 slit homolog 2 (Drosophila) 1.1136
TOP2B topoisomerase (DNA) II beta 180kDa 1.1136
TREX1 three prime repair exonuclease 1 1.1136
BCL10 B-cell CLL/lymphoma 10 1.1136
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.1136
SNCB synuclein, beta 1.11325
SCARB1 scavenger receptor class B, member 1 1.11151
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.11081
MCL1 myeloid cell leukemia 1 1.11081
STIP1 stress-induced phosphoprotein 1 1.11081
GLDC glycine dehydrogenase (decarboxylating) 1.10838
GADD45G growth arrest and DNA-damage-inducible, gamma 1.10838
GRB14 growth factor receptor-bound protein 14 1.10838
LSP1 lymphocyte-specific protein 1 1.10838
TFAM transcription factor A, mitochondrial 1.10734
TLR5 toll-like receptor 5 1.10596
ADRA2B adrenoceptor alpha 2B 1.10562
APLP1 amyloid beta (A4) precursor-like protein 1 1.10562
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.10562
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.10562
ZIC1 Zic family member 1 1.10562
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.10562
PCBP1 poly(rC) binding protein 1 1.10562
RAD50 RAD50 homolog (S. cerevisiae) 1.10388
BOK BCL2-related ovarian killer 1.10353
MMP3 matrix metallopeptidase 3 1.10353
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.10353
ILK integrin-linked kinase 1.10353
PDE4D phosphodiesterase 4D, cAMP-specific 1.10353
CREBBP CREB binding protein 1.10282
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.10033
DCXR dicarbonyl/L-xylulose reductase 1.09857
VTN vitronectin 1.09857
PLLP plasmolipin 1.09786
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.09786
TK2 thymidine kinase 2, mitochondrial 1.09786
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.09786
MADD MAP-kinase activating death domain 1.09786
DVL1 dishevelled segment polarity protein 1 1.09786
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.09506
EPOR erythropoietin receptor 1.09366
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 1.09366
ADORA3 adenosine A3 receptor 1.09366
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.09366
TMPO thymopoietin 1.09366
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.09366
EIF4A1 eukaryotic translation initiation factor 4A1 1.09366
ALDOC aldolase C, fructose-bisphosphate 1.09366
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.09262
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.09262
AHR aryl hydrocarbon receptor 1.0919
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.09119
ADCY2 adenylate cyclase 2 (brain) 1.09047
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.09047
KLK6 kallikrein-related peptidase 6 1.09047
INADL InaD-like (Drosophila) 1.09047
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.09011
PPAP2B phosphatidic acid phosphatase type 2B 1.09011
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.09011
HSPA2 heat shock 70kDa protein 2 1.09011
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.08904
EDN3 endothelin 3 1.08904
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.08904
SSTR2 somatostatin receptor 2 1.08904
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.08904
ARG1 arginase 1 1.08762
OGG1 8-oxoguanine DNA glycosylase 1.08513
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.08407
CHKA choline kinase alpha 1.08407
JUP junction plakoglobin 1.08407
FMO2 flavin containing monooxygenase 2 (non-functional) 1.08407
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.08372
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.08337
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.08337
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.08301
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.08301
GPRC5B G protein-coupled receptor, class C, group 5, member B 1.08301
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 1.08266
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.08231
TIMP3 TIMP metallopeptidase inhibitor 3 1.08019
PKM pyruvate kinase, muscle 1.08019
SESN2 sestrin 2 1.08019
F2 coagulation factor II (thrombin) 1.07911
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.07768
GSTA4 glutathione S-transferase alpha 4 1.07732
GSTO1 glutathione S-transferase omega 1 1.07696
ALPP alkaline phosphatase, placental 1.07625
CHRM5 cholinergic receptor, muscarinic 5 1.07625
PBX2 pre-B-cell leukemia homeobox 2 1.07589
GABPA GA binding protein transcription factor, alpha subunit 60kDa 1.07589
LZTFL1 leucine zipper transcription factor-like 1 1.07589
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.07589
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 1.07589
RPL21 ribosomal protein L21 1.07589
MET MET proto-oncogene, receptor tyrosine kinase 1.07518
EPO erythropoietin 1.07518
GRB10 growth factor receptor-bound protein 10 1.07482
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.07482
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.07482
ECH1 enoyl CoA hydratase 1, peroxisomal 1.07376
MARCKS myristoylated alanine-rich protein kinase C substrate 1.07376
NCF2 neutrophil cytosolic factor 2 1.07376
VDAC1 voltage-dependent anion channel 1 1.07376
EPHX2 epoxide hydrolase 2, cytoplasmic 1.07269
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.07163
TAAR1 trace amine associated receptor 1 1.07128
PSAT1 phosphoserine aminotransferase 1 1.07057
TLR3 toll-like receptor 3 1.07057
LTF lactotransferrin 1.07057
COX1 1.07057
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.06987
CDC23 cell division cycle 23 1.06987
MT1A metallothionein 1A 1.06952
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.06917
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.06881
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.06734
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.06734
PNPLA6 patatin-like phospholipase domain containing 6 1.06625
MT2A metallothionein 2A 1.06588
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.06588
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 1.06588
NINJ1 ninjurin 1 1.06588
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.06588
JAK2 Janus kinase 2 1.06552
ANXA5 annexin A5 1.06552
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.06406
KDR kinase insert domain receptor 1.06406
RGS9 regulator of G-protein signaling 9 1.06261
BPTF bromodomain PHD finger transcription factor 1.06225
MYBBP1A MYB binding protein (P160) 1a 1.06188
FGF12 fibroblast growth factor 12 1.06188
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.06188
CCL4 chemokine (C-C motif) ligand 4 1.06188
FAM46C family with sequence similarity 46, member C 1.06188
CALB1 calbindin 1, 28kDa 1.06152
TBXA2R thromboxane A2 receptor 1.06152
SNAI2 snail family zinc finger 2 1.06152
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.06152
GATA2 GATA binding protein 2 1.06152
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.06116
NPPB natriuretic peptide B 1.0608
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.06008
ADCY4 adenylate cyclase 4 1.05864
GRIK4 glutamate receptor, ionotropic, kainate 4 1.05828
NEUROD2 neuronal differentiation 2 1.05828
NCAN neurocan 1.05828
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.05828
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 1.05793
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.05793
ULBP2 UL16 binding protein 2 1.05793
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.05793
DDN dendrin 1.05757
PRRT1 proline-rich transmembrane protein 1 1.05757
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.05721
MX1 MX dynamin-like GTPase 1 1.05721
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.0561
MRPS18B mitochondrial ribosomal protein S18B 1.05573
GRK6 G protein-coupled receptor kinase 6 1.05573
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.05573
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.05535
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.05535
ARHGAP5 Rho GTPase activating protein 5 1.05535
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.05163
RRM2 ribonucleotide reductase M2 1.05126
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.05126
CKS1B CDC28 protein kinase regulatory subunit 1B 1.04868
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.04868
KLF9 Kruppel-like factor 9 1.04868
GHR growth hormone receptor 1.04868
CDC25B cell division cycle 25B 1.04868
PRDM2 PR domain containing 2, with ZNF domain 1.04868
AVPR1A arginine vasopressin receptor 1A 1.04868
ATR ATR serine/threonine kinase 1.04831
DCAF6 DDB1 and CUL4 associated factor 6 1.04647
MCRS1 microspherule protein 1 1.04647
ANXA1 annexin A1 1.04647
CCNB2 cyclin B2 1.04647
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.04574
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.04427
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.04427
TEK TEK tyrosine kinase, endothelial 1.04427
CPN1 carboxypeptidase N, polypeptide 1 1.04239
S100A4 S100 calcium binding protein A4 1.04239
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 1.04239
HES5 hes family bHLH transcription factor 5 1.04239
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.04239
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.04014
VIP vasoactive intestinal peptide 1.04014
CD47 CD47 molecule 1.04014
COL3A1 collagen, type III, alpha 1 1.03976
BECN1 beclin 1, autophagy related 1.03641
HMGB2 high mobility group box 2 1.03641
BHLHE40 basic helix-loop-helix family, member e40 1.03641
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.03604
SARS seryl-tRNA synthetase 1.03604
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.03604
SIRT3 sirtuin 3 1.03604
STXBP1 syntaxin binding protein 1 1.03604
CTNND1 catenin (cadherin-associated protein), delta 1 1.03567
MXD1 MAX dimerization protein 1 1.03567
MAP2K3 mitogen-activated protein kinase kinase 3 1.03567
CXCL14 chemokine (C-X-C motif) ligand 14 1.03567
AQR aquarius intron-binding spliceosomal factor 1.0353
DPF1 D4, zinc and double PHD fingers family 1 1.0353
TGFB2 transforming growth factor, beta 2 1.03493
CCNB1 cyclin B1 1.03493
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.03456
G0S2 G0/G1 switch 2 1.03345
TSC22D3 TSC22 domain family, member 3 1.03345
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.03271
GLUD1 glutamate dehydrogenase 1 1.03197
PNPLA2 patatin-like phospholipase domain containing 2 1.03159
PLP1 proteolipid protein 1 1.03009
HMGN2 high mobility group nucleosomal binding domain 2 1.02971
SIRT2 sirtuin 2 1.02971
GJA4 gap junction protein, alpha 4, 37kDa 1.02971
CLTB clathrin, light chain B 1.02971
HINT1 histidine triad nucleotide binding protein 1 1.02971
CUL3 cullin 3 1.02971
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.02858
ALPL alkaline phosphatase, liver/bone/kidney 1.02821
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.02783
ACACB acetyl-CoA carboxylase beta 1.02783
LYN LYN proto-oncogene, Src family tyrosine kinase 1.02783
LRP1 low density lipoprotein receptor-related protein 1 1.02783
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.02783
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.02783
OCLN occludin 1.02783
SCP2 sterol carrier protein 2 1.02783
CD36 CD36 molecule (thrombospondin receptor) 1.02708
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.02485
MIR150 microRNA 150 1.02485
IFRD1 interferon-related developmental regulator 1 1.02485
NOX4 NADPH oxidase 4 1.02485
RBBP5 retinoblastoma binding protein 5 1.02485
PKNOX2 PBX/knotted 1 homeobox 2 1.02447
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.02373
PF4 platelet factor 4 1.02373
HHIP hedgehog interacting protein 1.02373
PGAM1 phosphoglycerate mutase 1 (brain) 1.02373
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.02373
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.02373
IL18 interleukin 18 1.02336
GDF15 growth differentiation factor 15 1.02336
UBE2C ubiquitin-conjugating enzyme E2C 1.02188
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.01928
LMNA lamin A/C 1.01928
MCM6 minichromosome maintenance complex component 6 1.01928
AADAT aminoadipate aminotransferase 1.01814
APOE apolipoprotein E 1.01814
ITGA1 integrin, alpha 1 1.01776
TANK TRAF family member-associated NFKB activator 1.01776
PSEN2 presenilin 2 1.01776
H1FX H1 histone family, member X 1.01776
REPIN1 replication initiator 1 1.01474
CERS4 ceramide synthase 4 1.01437
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 1.01437
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 1.01361
FBXO45 F-box protein 45 1.01286
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 1.01249
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.01212
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 1.01212
WNT5A wingless-type MMTV integration site family, member 5A 1.01212
ALCAM activated leukocyte cell adhesion molecule 1.01212
LPIN1 lipin 1 1.01212
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 1.01174
PGK1 phosphoglycerate kinase 1 1.01062