Hypotrichosis Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A hair disease that is characterized by sparse hair on the scalp resulting from abnormal hair follicle development and has_material_basis in mutations in proteins involved in hair growth, division or proliferation of cells within hair follicles. (Human Disease Ontology, DOID_4535)
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Genes

45 genes involed in the disease Hypotrichosis from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AR androgen receptor 5.0
KRT85 keratin 85, type II 4.0
ST14 suppression of tumorigenicity 14 (colon carcinoma) 4.0
CDH3 cadherin 3, type 1, P-cadherin (placental) 4.0
LIPH lipase, member H 4.0
SPINK5 serine peptidase inhibitor, Kazal type 5 4.0
EPS8L3 EPS8-like 3 4.0
C3ORF52 chromosome 3 open reading frame 52 4.0
SOX18 SRY (sex determining region Y)-box 18 4.0
KRT25 keratin 25, type I 4.0
GJA1 gap junction protein, alpha 1, 43kDa 4.0
SNRPE small nuclear ribonucleoprotein polypeptide E 4.0
APCS amyloid P component, serum 4.0
HR hair growth associated 4.0
RPL21 ribosomal protein L21 4.0
ZPR1 ZPR1 zinc finger 4.0
RECQL4 RecQ protein-like 4 4.0
SASH1 SAM and SH3 domain containing 1 4.0
CDSN corneodesmosin 4.0
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 4.0
DSG1 desmoglein 1 4.0
DSG4 desmoglein 4 4.0
ARHGAP36 Rho GTPase activating protein 36 4.0
CRIPT cysteine-rich PDZ-binding protein 4.0
DSC3 desmocollin 3 4.0
ANTXR1 anthrax toxin receptor 1 4.0
RBM28 RNA binding motif protein 28 4.0
DPH2 DPH2 homolog (S. cerevisiae) 4.0
DPH1 diphthamide biosynthesis 1 4.0
ANAPC1 anaphase promoting complex subunit 1 4.0
POC1A POC1 centriolar protein A 4.0
WNT10A wingless-type MMTV integration site family, member 10A 4.0
ODC1 ornithine decarboxylase 1 4.0
PHF6 PHD finger protein 6 4.0
DNA2 DNA replication helicase/nuclease 2 4.0
KRT71 keratin 71, type II 4.0
KRT74 keratin 74, type II 4.0
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 4.0
APCDD1 adenomatosis polyposis coli down-regulated 1 4.0
DCAF17 DDB1 and CUL4 associated factor 17 4.0
AHSG alpha-2-HS-glycoprotein 4.0
LPAR6 lysophosphatidic acid receptor 6 4.0
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 4.0
EDNRA endothelin receptor type A 4.0
FOXN1 forkhead box N1 4.0