Hypotrichosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A hair disease that is characterized by sparse hair on the scalp resulting from abnormal hair follicle development and has_material_basis in mutations in proteins involved in hair growth, division or proliferation of cells within hair follicles. (Human Disease Ontology, DOID_4535)
External Link https://www.disgenet.org/browser/0/1/0/C0020678
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Genes

109 genes associated with the disease Hypotrichosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACKR3 atypical chemokine receptor 3
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
ANTXR1 anthrax toxin receptor 1
APCDD1 adenomatosis polyposis coli down-regulated 1
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDNF brain-derived neurotrophic factor
BRS3 bombesin-like receptor 3
CANT1 calcium activated nucleotidase 1
CCL2 chemokine (C-C motif) ligand 2
CCN2 cellular communication network factor 2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDSN corneodesmosin
CLDN1 claudin 1
CLMP CXADR-like membrane protein
COL11A1 collagen, type XI, alpha 1
CSMD1 CUB and Sushi multiple domains 1
CST6 cystatin E/M
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR6 chemokine (C-X-C motif) receptor 6
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
DCAF17 DDB1 and CUL4 associated factor 17
DCTN6 dynactin 6
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG4 desmoglein 4
DSP desmoplakin
EDA ectodysplasin A
EDA2R ectodysplasin A2 receptor
EDAR ectodysplasin A receptor
EDARADD EDAR-associated death domain
EDNRA endothelin receptor type A
ERBB3 erb-b2 receptor tyrosine kinase 3
FLNA filamin A, alpha
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJB6 gap junction protein, beta 6, 30kDa
GLUD1 glutamate dehydrogenase 1
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSN gelsolin
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HOXC13 homeobox C13
HR hair growth associated
HRAS Harvey rat sarcoma viral oncogene homolog
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL6 interleukin 6
KDF1 keratinocyte differentiation factor 1
KRT25 keratin 25, type I
KRT71 keratin 71, type II
KRT74 keratin 74, type II
KRT81 keratin 81, type II
KRT83 keratin 83, type II
KRT86 keratin 86, type II
LIPH lipase, member H
LIPN lipase, family member N
LMNA lamin A/C
LPAR2 lysophosphatidic acid receptor 2
LPAR6 lysophosphatidic acid receptor 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MTG1 mitochondrial ribosome-associated GTPase 1
MYD88 myeloid differentiation primary response 88
NIPAL4 NIPA-like domain containing 4
NME1 NME/NM23 nucleoside diphosphate kinase 1
NRG1 neuregulin 1
PERP PERP, TP53 apoptosis effector
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKP1 plakophilin 1
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
PRDX6 peroxiredoxin 6
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RPL21 ribosomal protein L21
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNRPE small nuclear ribonucleoprotein polypeptide E
SOX18 SRY (sex determining region Y)-box 18
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SSTR4 somatostatin receptor 4
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TGIF1 TGFB-induced factor homeobox 1
TGM1 transglutaminase 1
TICAM2 toll-like receptor adaptor molecule 2
TLR4 toll-like receptor 4
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPV3 transient receptor potential cation channel, subfamily V, member 3
WNT10A wingless-type MMTV integration site family, member 10A
XYLT1 xylosyltransferase I
ZMPSTE24 zinc metallopeptidase STE24