| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. (Gene Ontology, GO_0007252) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0007252 |
| Similar Terms | |
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7 genes participating in the I-kappaB phosphorylation biological process from the curated GO Biological Process Annotations 2025 dataset.
